Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing

(2018) Charissa Kim et al.   CELL

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation

(2018) Jason D. Buenrostro et al.   CELL

Histone Variant H2A.Z is Required for the Maintenance of Smooth Muscle Cell Identity as Revealed by Single-Cell Transcriptomics

(2018) Fang Yao et al.   CIRCULATION

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation

(2018) Monika M. Gladka et al.   CIRCULATION

THO Complex--Dependent Posttranscriptional Control Contributes to Vascular Smooth Muscle Cell Fate Decision

(2018) Li Wang et al.   CIRCULATION RESEARCH

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

The human heart contains distinct macrophage subsets with divergent origins and functions

(2018) Geetika Bajpai et al.   NATURE MEDICINE

A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart

(2018) Lavanya M Iyer et al.   NUCLEIC ACIDS RESEARCH

Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction

(2018) Yonggang Ma et al.   Translational Research

Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart

(2018) Daniel A. Skelly et al.   Cell Reports

A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility

(2018) Darren A. Cusanovich et al.   CELL

Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts

(2018) Peng Hu et al.   GENES & DEVELOPMENT

Single-Cell Sequencing of the Mammalian Heart

(2018) Bas Molenaar et al.   CIRCULATION RESEARCH

Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

(2018) Jared M. Churko et al.   Nature Communications

Heart failure

(2017) Marco Metra et al.   LANCET

IRF3 and type I interferons fuel a fatal response to myocardial infarction

(2017) Kevin R King et al.   NATURE MEDICINE

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Ensembl 2018

(2017) Daniel R Zerbino et al.   NUCLEIC ACIDS RESEARCH

p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure

(2017) Chih-Yang Huang et al.   Cell Death & Disease

Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo

(2017) Kelvin See et al.   Nature Communications

Region and cell-type resolved quantitative proteomic map of the human heart

(2017) Sophia Doll et al.   Nature Communications

Single-Cell Resolution of Temporal Gene Expression during Heart Development

(2016) Daniel M. DeLaughter et al.   DEVELOPMENTAL CELL

Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells

(2016) Guang Li et al.   DEVELOPMENTAL CELL

The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome

(2016) Elizabeth V. Wasmuth et al.   NUCLEIC ACIDS RESEARCH

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells

(2016) Qi Chen et al.   Nature Communications

Immune Cell and Other Noncardiomyocyte Regulation of Cardiac Hypertrophy and Remodeling

(2015) R. A. Frieler et al.   CIRCULATION

Recent Developments in Heart Failure

(2015) Sujith Dassanayaka et al.   CIRCULATION RESEARCH

Cardiac Nonmyocytes in the Hub of Cardiac Hypertrophy

(2015) T. Kamo et al.   CIRCULATION RESEARCH

Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction

(2015) Mihai Gheorghiade et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Left Ventricular Assist Devices

(2015) Donna Mancini et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

circlize implements and enhances circular visualization in R

(2014) Zuguang Gu et al.   BIOINFORMATICS

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Endothelial Cells Contribute to Generation of Adult Ventricular Myocytes during Cardiac Homeostasis

(2014) Bryan A. Fioret et al.   Cell Reports

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming

(2013) Li Wang et al.   Cell Stem Cell

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

C/EBP Transcription Factors Mediate Epicardial Activation During Heart Development and Injury

(2012) G. N. Huang et al.   SCIENCE

E4BP4 is a cardiac survival factor and essential for embryonic heart development

(2010) Yi-Jiun Weng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Chromatin regulation by Brg1 underlies heart muscle development and disease

(2010) Calvin T. Hang et al.   NATURE

The role of the unfolded protein response in the heart

(2007) Christopher C. Glembotski   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY