SPEN integrates transcriptional and epigenetic control of X-inactivation

Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

(2019) Tatyana B. Nesterova et al.   Nature Communications

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d

(2018) Philip Knuckles et al.   GENES & DEVELOPMENT

The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression

(2018) Susanne Bornelöv et al.   MOLECULAR CELL

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

(2018) Jan J Zylicz et al.   eLife

The Implication of Early Chromatin Changes in X Chromosome Inactivation

(2018) Jan Jakub Żylicz et al.   CELL

Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation

(2017) Houda Belaghzal et al.   METHODS

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

(2017) Maud Borensztein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

(2017) Maud Borensztein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition

(2017) Yun Huang et al.   eLife

An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

(2017) Peter J Skene et al.   eLife

RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure

(2016) Zhipeng Lu et al.   CELL

Structural organization of the inactive X chromosome in the mouse

(2016) Luca Giorgetti et al.   NATURE

m6A RNA methylation promotes XIST-mediated transcriptional repression

(2016) Deepak P. Patil et al.   NATURE

A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes

(2016) Franz Oswald et al.   NUCLEIC ACIDS RESEARCH

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity

(2016) Joan Barau et al.   SCIENCE

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

A general method to improve fluorophores for live-cell and single-molecule microscopy

(2015) Jonathan B Grimm et al.   NATURE METHODS

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

(2015) A. Minajigi et al.   SCIENCE

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

(2015) Benoit Moindrot et al.   Cell Reports

Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells

(2015) Asun Monfort et al.   Cell Reports

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

The Two Active X Chromosomes in Female ESCs Block Exit from the Pluripotent State by Modulating the ESC Signaling Network

(2014) Edda G. Schulz et al.   Cell Stem Cell

The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

(2013) J. M. Engreitz et al.   SCIENCE

MassChroQ: A versatile tool for mass spectrometry quantification

(2011) Benoît Valot et al.   PROTEOMICS

RNA-Seq analysis to capture the transcriptome landscape of a single cell

(2010) Fuchou Tang et al.   Nature Protocols

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis

(2009) J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA