Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro

Spreading of α-Synuclein and Tau: A Systematic Comparison of the Mechanisms Involved

(2019) Eftychia Vasili et al.   Frontiers in Molecular Neuroscience

Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer’s disease

(2019) Maike Hartlage-Rübsamen et al.   Acta Neuropathologica Communications

Diverse Misfolded Conformational Strains and Cross-seeding of Misfolded Proteins Implicated in Neurodegenerative Diseases

(2019) Kwang Hun Lim   Frontiers in Molecular Neuroscience

Association of microtubule-associated protein tau gene polymorphisms with the risk of sporadic Alzheimer's disease: a meta-analysis

(2018) Hai Yuan et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation

(2018) Maike Hartlage-Rübsamen et al.   MOLECULES

α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton

(2018) Dalila G. Ordonez et al.   NEURON

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies

(2018) Iryna Prots et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development

(2017) Dilina Tuerde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Microtubule-Associated Protein Tau Mediates the Organization of Microtubules and Their Dynamic Exploration of Actin-Rich Lamellipodia and Filopodia of Cortical Growth Cones

(2017) Sayantanee Biswas et al.   JOURNAL OF NEUROSCIENCE

Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates

(2017) Sean Chia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau

(2017) Yunior Cabrales Fontela et al.   Nature Communications

Atypical, non-standard functions of the microtubule associated Tau protein

(2017) Ioannis Sotiropoulos et al.   Acta Neuropathologica Communications

Qualitative analysis of Parkinson’s disease information on social media: the case of YouTube™

(2017) Ibrahim Saleh Al-Busaidi et al.   EPMA Journal

Polymorphism of Amyloid Fibrils In Vivo

(2016) Karthikeyan Annamalai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes

(2016) Andreas Becker et al.   BIOLOGICAL CHEMISTRY

Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity

(2016) Sha Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis

(2016) Jinghui Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant

(2016) Claire Hoenen et al.   PLoS One

Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis

(2015) Chris Stinton et al.   AMERICAN JOURNAL OF PSYCHIATRY

Steady-state and time-resolved Thioflavin-T fluorescence can report on morphological differences in amyloid fibrils formed by Aβ(1-40) and Aβ(1-42)

(2015) David J. Lindberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lewy body dementias

(2015) Zuzana Walker et al.   LANCET

The amyloid state and its association with protein misfolding diseases

(2014) Tuomas P. J. Knowles et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour

(2014) Giuliana Fusco et al.   Nature Communications

Wildtype and A30P Mutant Alpha-Synuclein Form Different Fibril Structures

(2013) Søren Bang Nielsen et al.   PLoS One

Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism

(2013) S. I. A. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of Ser129 phosphorylation of α-synuclein in neurodegeneration of Parkinson’s disease: a review of in vivo models

(2013) Hiroyasu Sato et al.   REVIEWS IN THE NEUROSCIENCES

Cross-seeding effects of amyloid β-protein and α-synuclein

(2012) Kenjiro Ono et al.   JOURNAL OF NEUROCHEMISTRY

N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation

(2012) Dagmar Schlenzig et al.   JOURNAL OF NEUROCHEMISTRY

Microglial Activation and Antioxidant Responses Induced by the Parkinson’s Disease Protein α-Synuclein

(2012) Dawn Béraud et al.   Journal of Neuroimmune Pharmacology

Mechanisms of Protein Oligomerization: Inhibitor of Functional Amyloids Templates α-Synuclein Fibrillation

(2012) Istvan Horvath et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

Pyroglutamate Formation Influences Solubility and Amyloidogenicity of Amyloid Peptides

(2009) Dagmar Schlenzig et al.   BIOCHEMISTRY

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

(2008) Igor F. Tsigelny et al.   PLoS One

The phosphorylation state of Ser-129 in human  -synuclein determines neurodegeneration in a rat model of Parkinson disease

(2008) O. S. Gorbatyuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA