期刊
MOLECULES
卷 25, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/molecules25030493
关键词
gedunin; limonoid; Meliaceae family; bioactive compound; biological activity
资金
- Bio4Life4You
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Several biological activities have been attributed to gedunin, including antibacterial, insecticidal, antimalarial, antiallergic, anti-inflammatory, anticancer, and neuroprotective effects. The discovery of gedunin as a heat shock protein (Hsp) inhibitor represented a very important landmark for its application as a biological therapeutic agent. The current study is a critical literature review based on the several biological activities so far described for gedunin, its therapeutic effect on some human diseases, and future directions of research for this natural compound.
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