CRISPR‐Cas systems in oral microbiome: From immune defense to physiological regulation

Deletion of cas3 gene in Streptococcus mutans affects biofilm formation and increases fluoride sensitivity

(2019) Boyu Tang et al.   ARCHIVES OF ORAL BIOLOGY

Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

(2019) Kevin J Forsberg et al.   eLife

Drug Resistance and Gene Transfer Mechanisms in Respiratory/Oral Bacteria

(2018) S. Jiang et al.   JOURNAL OF DENTAL RESEARCH

Genome Editing: A New Horizon for Oral and Craniofacial Research

(2018) N. Yu et al.   JOURNAL OF DENTAL RESEARCH

Genome editing in Streptococcus mutans through self-targeting CRISPR arrays

(2018) Tao Gong et al.   Molecular Oral Microbiology

The oral microbiota: dynamic communities and host interactions

(2018) Richard J. Lamont et al.   NATURE REVIEWS MICROBIOLOGY

Deciphering, Communicating, and Engineering the CRISPR PAM

(2017) Ryan T. Leenay et al.   JOURNAL OF MOLECULAR BIOLOGY

Anti-CRISPR: discovery, mechanism and function

(2017) April Pawluk et al.   NATURE REVIEWS MICROBIOLOGY

Diversity and evolution of class 2 CRISPR–Cas systems

(2017) Sergey Shmakov et al.   NATURE REVIEWS MICROBIOLOGY

An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9

(2017) Alexander P. Hynes et al.   Nature Microbiology

Disabling Cas9 by an anti-CRISPR DNA mimic

(2017) Jiyung Shin et al.   Science Advances

DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation

(2016) Emil Mladenov et al.   SEMINARS IN CANCER BIOLOGY

Crystal Structure of Streptococcus pyogenes Cas1 and Its Interaction with Csn2 in the Type II CRISPR-Cas System

(2016) Donghyun Ka et al.   STRUCTURE

Global transcription of CRISPR loci in the human oral cavity

(2015) Andrew G Lum et al.   BMC GENOMICS

Regulation of oxidative response and extracellular polysaccharide synthesis by a diadenylate cyclase in S treptococcus mutans

(2015) Xingqun Cheng et al.   ENVIRONMENTAL MICROBIOLOGY

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Functional signatures of oral dysbiosis during periodontitis progression revealed by microbial metatranscriptome analysis

(2015) Susan Yost et al.   Genome Medicine

Characterization of bacteriophage communities and CRISPR profiles from dental plaque

(2014) Mayuri Naidu et al.   BMC MICROBIOLOGY

Comparative genome analysis and identification of competitive and cooperative interactions in a polymicrobial disease

(2014) Akiko Endo et al.   ISME Journal

Role of the Streptococcus mutans CRISPR-Cas Systems in Immunity and Cell Physiology

(2014) M. A. Serbanescu et al.   JOURNAL OF BACTERIOLOGY

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

(2014) Robert J Citorik et al.   NATURE BIOTECHNOLOGY

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

CRISPR Regulation of Intraspecies Diversification by Limiting IS Transposition and Intercellular Recombination

(2013) Takayasu Watanabe et al.   Genome Biology and Evolution

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

(2013) Prashant Mali et al.   NATURE BIOTECHNOLOGY

Repair of Double-Strand Breaks by End Joining

(2013) K. K. Chiruvella et al.   Cold Spring Harbor Perspectives in Biology

CRISPR-Cas systems and RNA-guided interference

(2013) Rodolphe Barrangou   Wiley Interdisciplinary Reviews-RNA

Comparisons of clustered regularly interspaced short palindromic repeats and viromes in human saliva reveal bacterial adaptations to salivary viruses

(2012) David T. Pride et al.   ENVIRONMENTAL MICROBIOLOGY

CRISPR-Cas, a Prokaryotic Adaptive Immune System, in Endodontic, Oral, and Multidrug-resistant Hospital-acquired Enterococcus faecalis

(2012) Katie M. Burley et al.   JOURNAL OF ENDODONTICS

Essential Features and Rational Design of CRISPR RNAs that Function with the Cas RAMP Module Complex to Cleave RNAs

(2012) Caryn R. Hale et al.   MOLECULAR CELL

RNA-guided genetic silencing systems in bacteria and archaea

(2012) Blake Wiedenheft et al.   NATURE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Nature and Intensity of Selection Pressure on CRISPR-Associated Genes

(2011) N. Takeuchi et al.   JOURNAL OF BACTERIOLOGY

Evolution and classification of the CRISPR–Cas systems

(2011) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

The oral microbiome in health and disease and the potential impact on personalized dental medicine

(2011) MF Zarco et al.   ORAL DISEASES

Comparison of genotypic and phenotypic cluster analyses of virulence determinants and possible role of CRISPR elements towards their incidence in Enterococcus faecalis and Enterococcus faecium

(2011) Angela G. Lindenstrauß et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY

A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

(2010) Mohan Babu et al.   MOLECULAR MICROBIOLOGY

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

(2010) Josiane E. Garneau et al.   NATURE

Periodontitis: a polymicrobial disruption of host homeostasis

(2010) Richard P. Darveau   NATURE REVIEWS MICROBIOLOGY

Self-targeting by CRISPR: gene regulation or autoimmunity?

(2010) Adi Stern et al.   TRENDS IN GENETICS

Multidrug-Resistant Enterococci Lack CRISPR-cas

(2010) K. L. Palmer et al.   mBio