The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation

VPAC1 couples with TRPV4 channel to promote calcium-dependent gastric cancer progression via a novel autocrine mechanism

(2019) Bo Tang et al.   ONCOGENE

Enhanced junctional epithelial permeability in TRPV4‐deficient mice

(2019) Tomoko Kitsuki et al.   JOURNAL OF PERIODONTAL RESEARCH

TRPV4 promotes the migration and invasion of glioma cells via AKT/Rac1 signaling

(2018) Qing Ou-yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacological inhibition of TRPV4 channel suppresses malignant biological behavior of hepatocellular carcinoma via modulation of ERK signaling pathway

(2018) Yu Fang et al.   BIOMEDICINE & PHARMACOTHERAPY

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

(2018) Changwei Dou et al.   GASTROENTEROLOGY

RAP2 mediates mechanoresponses of the Hippo pathway

(2018) Zhipeng Meng et al.   NATURE

GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas

(2017) Yurie Mikami et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Calmodulin kinases: essential regulators in health and disease

(2017) Sayaka Takemoto-Kimura et al.   JOURNAL OF NEUROCHEMISTRY

TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein

(2017) W H Lee et al.   Oncogenesis

4-isopropylcyclohexanol has potential analgesic effects through the inhibition of anoctamin 1, TRPV1 and TRPA1 channel activities

(2017) Yasunori Takayama et al.   Scientific Reports

Oral cancer: Deregulated molecular events and their use as biomarkers

(2016) Nicoleta Sinevici et al.   ORAL ONCOLOGY

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy

(2015) R K Adapala et al.   ONCOGENE

Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways

(2015) P Jie et al.   Cell Death & Disease

Current concepts and future of noninvasive procedures for diagnosing oral squamous cell carcinoma - a systematic review

(2015) Esam Omar   Head & Face Medicine

Force Engages Vinculin and Promotes Tumor Progression by Enhancing PI3K Activation of Phosphatidylinositol (3,4,5)-Triphosphate

(2014) Matthew G. Rubashkin et al.   CANCER RESEARCH

A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures

(2014) S. Matsumoto et al.   EMBO JOURNAL

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target

(2014) S Fujii et al.   ONCOGENE

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress

(2009) Suelhem A. Mendoza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

TRPV4 Channels Mediate Cyclic Strain–Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling

(2009) Charles K. Thodeti et al.   CIRCULATION RESEARCH

Global epidemiology of oral and oropharyngeal cancer

(2008) Saman Warnakulasuriya   ORAL ONCOLOGY