Protein aggregate formation permits millennium-old brain preservation

A guide to ancient protein studies

(2018) Jessica Hendy et al.   Nature Ecology & Evolution

Neurofilaments as biomarkers in neurological disorders

(2018) Michael Khalil et al.   Nature Reviews Neurology

Evolutionary interplay between structure, energy and epistasis in the coat protein of theϕX174 phage family

(2017) Rodrigo A. F. Redondo et al.   Journal of the Royal Society Interface

Preservation of protein expression systems at elevated temperatures for portable therapeutic production

(2017) David K. Karig et al.   Journal of the Royal Society Interface

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

A fossil protein chimera; difficulties in discriminating dinosaur peptide sequences from modern cross-contamination

(2017) Michael Buckley et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Dancing Protein Clouds: The Strange Biology and Chaotic Physics of Intrinsically Disordered Proteins

(2016) Vladimir N. Uversky   JOURNAL OF BIOLOGICAL CHEMISTRY

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

(2016) Bob Olsson et al.   LANCET NEUROLOGY

Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases

(2016) Mehtap Bacioglu et al.   NEURON

Identification of proteins from 4200-year-old skin and muscle tissue biopsies from ancient Egyptian mummies of the first intermediate period shows evidence of acute inflammation and severe immune response

(2016) Jana Jones et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne

(2016) Frido Welker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular evidence of keratin and melanosomes in feathers of the Early Cretaceous birdEoconfuciusornis

(2016) Yanhong Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteins and their modifications in a medieval mummy

(2016) Ivan Mikšík et al.   PROTEIN SCIENCE

Protein sequences bound to mineral surfaces persist into deep time

(2016) Beatrice Demarchi et al.   eLife

Glial fibrillary acidic protein is a body fluid biomarker for glial pathology in human disease

(2015) Axel Petzold   BRAIN RESEARCH

Proteins in Art, Archaeology, and Paleontology: From Detection to Identification

(2015) Sophie Dallongeville et al.   CHEMICAL REVIEWS

Protein power

(2015) R. F. Service   SCIENCE

Behavioral and Psychiatric Symptoms in Prion Disease

(2014) Andrew Thompson et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Idiopathic Intracranial Hypertension Treatment Trial

(2014) Deborah I. Friedman et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Biophysics of protein evolution and evolutionary protein biophysics

(2014) T. Sikosek et al.   Journal of the Royal Society Interface

Unlocking Ancient Protein Palimpsests

(2014) E. Cappellini et al.   SCIENCE

Body fluid biomarkers in multiple sclerosis

(2013) Manuel Comabella et al.   LANCET NEUROLOGY

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury

(2013) J. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

(2013) J. A. Moreno et al.   Science Translational Medicine

Neurofilament sidearms modulate parallel and crossed-filament orientations inducing nematic to isotropic and re-entrant birefringent hydrogels

(2013) Joanna Deek et al.   Nature Communications

Versatility from Protein Disorder

(2012) M. M. Babu et al.   SCIENCE

New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing

(2012) Andreas Keller et al.   Nature Communications

The neurofilament light chain is not stable in vitro

(2011) Marleen J.A. Koel-Simmelink et al.   ANNALS OF NEUROLOGY

Axonal damage in the making: Neurofilament phosphorylation, proton mobility and magnetisation transfer in multiple sclerosis normal appearing white matter

(2011) A. Petzold et al.   EXPERIMENTAL NEUROLOGY

Exceptional preservation of a prehistoric human brain from Heslington, Yorkshire, UK

(2011) Sonia O’Connor et al.   JOURNAL OF ARCHAEOLOGICAL SCIENCE

Multiplexed protein analysis using encoded antibody-conjugated microbeads

(2011) N. Theilacker et al.   Journal of the Royal Society Interface

Multidisciplinary analysis of a mummified cranium claimed to be that of a medieval execution victim

(2011) Martin J. Smith et al.   Archaeological and Anthropological Sciences

A method to solubilise protein aggregates for immunoassay quantification which overcomes the neurofilament “hook” effect

(2010) Ching-Hua Lu et al.   JOURNAL OF NEUROSCIENCE METHODS

Prion-like transmission of protein aggregates in neurodegenerative diseases

(2010) Patrik Brundin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Archaeologists See Big Promise In Going Molecular

(2010) J. Travis   SCIENCE

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

(2010) Peter Csermely et al.   TRENDS IN BIOCHEMICAL SCIENCES

Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans

(2010) Della C. David et al.   PLOS BIOLOGY

Neurofilament ELISA validation

(2009) Axel Petzold et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Gel-expanded to gel-condensed transition in neurofilament networks revealed by direct force measurements

(2009) Roy Beck et al.   NATURE MATERIALS

Molecular Mechanisms and Pathophysiology of Necrotic Cell Death

(2008) Nele Vanlangenakker et al.   CURRENT MOLECULAR MEDICINE

Phosphorylation and compactness of neurofilaments in multiple sclerosis: Indicators of axonal pathology

(2008) Axel Petzold et al.   EXPERIMENTAL NEUROLOGY

The Phosphorylated Axonal Form of the Neurofilament Subunit NF-H (pNF-H) as a Blood Biomarker of Traumatic Brain Injury

(2008) Kevin J. Anderson et al.   JOURNAL OF NEUROTRAUMA

Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice

(2008) J. D. F. Wadsworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time-dependent evolution of tissue markers by MALDI-MS imaging

(2008) Richard J. A. Goodwin et al.   PROTEOMICS

THIRD INTERNATIONAL SYMPOSIUM ON BIOMOLECULAR ARCHAEOLOGY: Hope for the Rhone's Missing Sturgeon

(2008) J. Travis   SCIENCE

The Threat of Instability: Neurodegeneration Predicted by Protein Destabilization and Aggregation Propensity

(2008) Elizabeth M Meiering   PLOS BIOLOGY