Article
Clinical Neurology
Ding Chen, Chang Xiao, Wangyan Xiao, Linjing Lou, Zhuo Gao, Xinlun Li
Summary: This study explored the risk factors for cognitive impairment in patients undergoing maintenance hemodialysis (MHD) and constructed a predictive model with a high predictive value for cognitive impairment. The factors associated with an increased risk of cognitive impairment in MHD patients were age, duration of dialysis, and smoking status.
Article
Urology & Nephrology
Kelly H. Beers, C. John Sperati, David S. Weisman, Khaled Abdel-Kader, Sandeep Soman, Laura Plantinga, Michael J. Choi, Bernard G. Jaar, Raquel C. Greer
Summary: The article discusses the role, challenges, and improvement strategies of primary care for patients receiving hemodialysis, while also suggesting future research needs for enhancing primary care delivery for this high-risk population.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)
Review
Urology & Nephrology
Maurizio Bossola, S. Susan Hedayati, Astrid D. H. Brys, L. Parker Gregg
Summary: Fatigue is a common symptom in patients undergoing hemodialysis that affects their quality of life. There is limited understanding of the associated risk factors and pathophysiology. Several hypotheses have been proposed to explain the pathophysiology, but there is currently no convincing data to support them. Fatigue is associated with various clinical factors, including cardiovascular and hemodynamic effects of the dialysis procedure, laboratory abnormalities, depression, and physical inactivity. Further robust studies are needed to establish the pathophysiology and management of this symptom.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2023)
Article
Clinical Neurology
Melissa Schorr, Mariah Zalitach, Cindy House, Janice Gomes, Conor J. Wild, Fabio R. Salerno, Christopher McIntyre
Summary: Abnormalities in cognitive function are common among patients receiving hemodialysis (HD) and are associated with impairments in verbal processing, reasoning, and short-term memory. These impairments may be attributed to the HD treatment itself. Further research is needed to understand the development of cognitive impairment in this patient population and to test interventions aimed at preventing or slowing its progression.
FRONTIERS IN NEUROLOGY
(2022)
Article
Medicine, General & Internal
Rachel L. Nosheny, Daniel Yen, Taylor Howell, Monica Camacho, Krista Moulder, Shilpa Gummadi, Chau Bui, Sandhya Kannan, Miriam T. Ashford, Kristen Knight, Connie Mayo, Maureen McMillan, Ronald C. Petersen, Nikki H. Stricker, Erik D. Roberson, Carol Chambless, Adam Gersteneker, Roy Martin, Richard Kennedy, Yue Zhang, Walter Kukull, Derek Flenniken, Juliet Fockler, Diana Truran, R. Scott Mackin, Michael W. Weiner, John C. Morris, Yan Li
Summary: The study found high concordance between eCDR and CDR, suggesting potential use for screening and assessment of cognitive and functional decline related to Alzheimer disease in older adults. Continued optimization and validation in diverse cohorts in remote settings are important for evaluating scalability and utility in clinical research, trials, and health care settings.
Article
Clinical Neurology
Xiaolin Tian, Xiaoshuang Xia, Haibo Yu, Haiyan Chen, Aili Jiang, Li Xin
Summary: Cognitive impairment in patients undergoing maintenance hemodialysis (MHD) is a significant concern. This study suggests a high prevalence of cognitive dysfunction in MHD patients without a history of stroke, with attention and executive abilities being significantly affected. Lower hemoglobin levels and higher levels of parathyroid hormone (PTH) and uric acid are associated with cognitive impairment, while diabetes and depressive and anxiety states may worsen cognitive dysfunction in MHD patients.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Article
Clinical Neurology
Sheridan D. Chappelle, Christina Gigliotti, Gabriel C. Leger, Guerry M. Peavy, Diane M. Jacobs, Sarah J. Banks, Emily A. Little, Douglas Galasko, David P. Salmon
Summary: Remote screening for cognitive impairment associated with Alzheimer's disease is important due to the aging population and possible treatment options. In this study, the Telephone Interview for Cognitive Status (TICS) and the telephone adaptation of the Montreal Cognitive Assessment (T-MoCA) were effective in detecting cognitive impairment remotely, and both tests correlated with AD biomarkers.
ALZHEIMERS & DEMENTIA
(2023)
Article
Psychiatry
Maolu Tian, Jing Yuan, Pinghong He, Fangfang Yu, Changzhu Long, Yan Zha
Summary: This study aimed to explore the effect of lean-to-fat (L/F) tissue ratio on the risk of incident cognitive impairment in patients undergoing maintenance hemodialysis (MHD). It found that the L/F tissue ratio, rather than BMI, was an independent risk factor of incident cognitive impairment in MHD patients.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Urology & Nephrology
Wenmei Lv, Hualong Liao, Xue Wang, Shaobin Yu, Yuan Peng, Xianghong Li, Ping Fu, Huaihong Yuan, Yu Chen
Summary: This study developed an assistant tool based on machine learning for early frailty screening in patients receiving maintenance hemodialysis. After feature selection, data split and oversampling, a voting classifier based on Support Vector Machine, Adaptive Boosting and Naive Bayes achieved a good screening performance.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2023)
Article
Medicine, General & Internal
Sinee Disthabanchong, Sarunya Saeseow, Sirote Khunapornphairote, Ronnarat Suvikapakornkul, Yodying Wasutit, Jumroon Tungkeeratichai
Summary: Parathyroidectomy is associated with improvement in nutritional status in maintenance hemodialysis patients, especially for those with severe hyperparathyroidism. This finding is crucial as protein-energy wasting is common in kidney failure patients and can have negative impacts on survival and outcomes.
FRONTIERS IN MEDICINE
(2023)
Review
Public, Environmental & Occupational Health
Spela Bogataj, Katja Kurnik Mesaric, Maja Pajek, Tanja Petrusic, Jernej Pajek
Summary: The present review suggests that physical exercise might improve or at least not worsen cognitive performance in HD patients, whereas the effect of cognitive training has not yet been adequately studied. More sensitive and specific cognitive tests are needed to adequately measure the effects of interventions in the HD population.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Endocrinology & Metabolism
Yidan Guo, Ru Tian, Pengpeng Ye, Xin Li, Guogang Li, Fangping Lu, Yingchun Ma, Yi Sun, Yuzhu Wang, Yuefei Xiao, Qimeng Zhang, Xuefeng Zhao, Haidan Zhao, Yang Luo
Summary: A study found that cognitive impairment is associated with all-cause mortality in hemodialysis patients, especially in the executive and memory cognitive domains. These findings suggest that detecting impairments in these cognitive domains may help in the early identification of hemodialysis patients at risk of death.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Neurosciences
Aoyu Li, Jingwen Li, Dongxu Zhang, Wei Wu, Juanjuan Zhao, Yan Qiang
Summary: Advancements in mobile computing platforms and wearable devices have allowed for continuous monitoring of patients with mild cognitive impairment (MCI) and their daily activities. This study investigated the feasibility and validity of using digital cognitive tests and physiological sensors to assess MCI. The results showed promising classification accuracy and identified key differences in cognitive performance and physiological markers between MCI patients and healthy controls.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Urology & Nephrology
Ping-Hsun Wu, Yi-Ting Lin, Jia-Sin Liu, Yi-Chun Tsai, Mei-Chuan Kuo, Yi-Wen Chiu, Shang-Jyh Hwang, Juan-Jesus Carrero
Summary: This study compared the health outcomes associated with the two most commonly used beta-blockers, carvedilol and bisoprolol, in patients undergoing hemodialysis, finding that bisoprolol initiation was associated with a lower 2-year risk of death and major adverse cardiovascular events, mainly due to lower risks of heart failure and ischemic stroke.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Oncology
Wendong Li, Jing Wang, Yanqin Wang, Rui Guan, Fan Zhao, Rongrong Zhang
Summary: The study found that hemodialysis combined with acupuncture and blood perfusion can regulate immune function, increase blood calcium content without affecting nutritional status, but it has no significant effect on the efficacy in patients.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2023)