Article
Psychology, Multidisciplinary
Yan Zhou, Xue-Ping Zhu, Jing-Jing Shi, Guo-Zhen Yuan, Zi-Ang Yao, Yu-Guang Chu, Shuai Shi, Qiu-Lei Jia, Ting Chen, Yuan-Hui Hu
Summary: This study conducted a bibliometric analysis on the association between coronary heart disease (CHD) and depression or anxiety, identifying leading authors, institutions, and countries. The research hotspots were found to be the relationship between depression and CHD, depression and myocardial infarction, and characteristics of women suffering depression after MI. Potential future research directions include treating depression in CHD patients with multimorbidity, assessing psychometric properties of instruments for depression and anxiety in CHD patients, exploring depression or anxiety in post-PCI patients, and investigating other mental diseases in CHD patients.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Wen-Yi Zhang, Nan Nan, Yi He, Hui-Juan Zuo, Xian-Tao Song, Min Zhang, Yuan Zhou
Summary: This study aimed to assess the prevalence of depression and anxiety in CHD patients and explore the association between established cardiovascular risk factors and depression as well as anxiety. The study found that the prevalence rates of depression and anxiety in CHD patients were 8.2% and 5.4%, respectively. Female gender, smoking, and hyperlipidemia were associated with a higher occurrence of depression, while female gender was associated with a higher occurrence of anxiety.
PSYCHOLOGY HEALTH & MEDICINE
(2023)
Review
Pharmacology & Pharmacy
Baofu Wang, Yu Teng, Yang Li, Sijia Lai, Yang Wu, Shiqi Chen, Tong Li, Xiaowan Han, Hufang Zhou, Yu Wang, Ziwen Lu, Haiyan Li, Yukun Ding, Liang Ma, Mingjing Zhao, Xian Wang
Summary: This study found that Chinese herbal medicine showed significant efficacy in treating coronary heart disease patients with anxiety or depression, especially in improving the symptom of angina pectoris. The active compounds of Chinese herbal medicine could simultaneously act on the pathological targets of CHD, anxiety, and depression, with advantages of multiple effective components and multiple targets compared with Western medicine.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Plant Sciences
Qian Liu, Mengxi Wang, Haiyan Wang, Haitao Xie, Jie Han, Jiandong Chen, Peng Yu, Le Shen, Yehui Li, Ruina Tian, Xiaohu Chen
Summary: This study aimed to systematically evaluate the efficacy and safety of Xinkeshu (XKS) for coronary heart disease (CHD) complicated with anxiety or depression. The study included 18 randomized controlled trials (RCTs) with a total of 1907 subjects. The results showed that compared with single-use western medicine, XKS combined with western medicine significantly reduced anxiety and depression scores, improved clinical efficacy, and had mild adverse reactions. However, more high-quality RCTs are needed to validate the conclusions.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Psychology, Multidisciplinary
Toril Dammen, Kristoffer Tunheim, John Munkhaugen, Costas Papageorgiou
Summary: The study evaluates the feasibility of attention training technique (ATT) in coronary heart disease (CHD) patients with symptoms of anxiety and depression. The results suggest that ATT in a group format appears to be a feasible stand-alone metacognitive treatment for CHD patients, effectively reducing anxiety, depression, and other related symptoms.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Ashley S. Manchanda, Alan C. Kwan, Mariko Ishimori, Louise E. J. Thomson, Debiao Li, Daniel S. Berman, C. Noel Bairey Merz, Caroline Jefferies, Janet Wei
Summary: Chest pain is a common symptom in patients with systemic lupus erythematosus (SLE), and approximately half of these patients are suspected to have coronary microvascular dysfunction (CMD). It is crucial to assess cardiovascular risk and diagnose possible CMD in these patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jaskanwal D. S. Sara, Ali Ahmad, Takumi Toya, Laura Suarez Pardo, Lilach O. Lerman, Amir Lerman
Summary: Anxiety disorders are significantly associated with coronary endothelial dysfunction in women presenting with chest pain and nonobstructive coronary artery disease, potentially serving as a mechanism underlying the association between anxiety disorders and coronary artery disease and its complications.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Lina Wang, Yangli Sun, Jie Zhan, Zhiyuan Wu, Peiming Zhang, Xiaopeng Wen, Shuqi Ge, Xu Han, Liming Lu
Summary: The meta-analysis suggests that exercise therapy may effectively alleviate anxiety and depression symptoms in patients with coronary heart disease, as well as improve aerobic fitness and athletic endurance. Rigorous research is needed to further confirm these findings.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Plant Sciences
Mingtai Chen, Mengnan Liu, Xin Guo, Jie Zhou, Huayi Yang, Guofu Zhong, Ling Men, Ying Xie, Guangdong Tong, Qiang Liu, Jienan Luan, Hua Zhou
Summary: This meta-analysis evaluated the clinical effects of Xinkeshu tablets (XKS) for treating coronary heart disease (CHD) patients with anxiety and depression after percutaneous coronary intervention (PCI). The results suggested that XKS combined with conventional treatment significantly improved anxiety and depression scores, as well as blood lipid levels. However, more rigorous clinical trials are needed due to the limitations of the included studies.
Article
Psychology, Multidisciplinary
Kristoffer Tunheim, Toril Dammen, Silje Baardstu, Torbjorn Moum, John Munkhaugen, Costas Papageorgiou
Summary: Psychological distress, including depression and anxiety, and Type-D personality are prevalent in patients with coronary heart disease (CHD) and associated with poor cardiovascular outcomes. Worry and rumination may be core features responsible for driving psychological distress in these patients. The study found an overlap between depression and negative affectivity, with worry being most strongly associated with anxiety and rumination being most strongly associated with depression and negative affectivity. Targeting worry and/or rumination in the treatment of CHD outpatients presenting with symptoms of psychological distress could be beneficial.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
James A. Blumenthal, Patrick J. Smith, Wei Jiang, Alan Hinderliter, Lana L. Watkins, Benson M. Hoffman, William E. Kraus, Stephanie Mabe, Lawrence Liao, Jonathan Davidson, Andrew Sherwood
Summary: Anxiety is common among patients with coronary heart disease and is associated with a worse prognosis. A clinical trial showed that escitalopram, but not exercise, was effective in reducing anxiety and depression. Participants randomized to exercise reported higher levels of physical activity at1-year follow-up but did not experience a decrease in anxiety or depression.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Medicine, General & Internal
Rei-Yeuh Chang, Sheri Hsueh-Hua Ho, Han-Lin Tsai, Malcolm Koo
Summary: The causes of noncardiac chest pain may be related to anxiety, depression, and chronic liver disease. This study found a significant association between anxiety, depression, and alcoholic liver disease in patients with noncardiac chest pain. Fatty liver disease and chronic hepatitis C were also associated with anxiety and depression, respectively. Clinicians should be aware of these correlations in their practice.
Article
Health Care Sciences & Services
Noor Hanita Zaini, Khatijah Lim Abdullah, Raja Amin Raja Mokhtar, Karuthan Chinna, Shahrul Bahyah Kamaruzzaman
Summary: This study aimed to assess the relationship between psychological distress and demographic data in coronary artery bypass graft (CABG) surgery patients. The results showed that the levels of anxiety, depression, and pain were significant, particularly among older patients. Participants with moderate anxiety levels were more likely to be aged between 60 and 74 years old, married, and have a tertiary level education.
Article
Psychology, Multidisciplinary
Toril Dammen, Kristoffer Tunheim, John Munkhaugen, Ole Klungsoyr, Costas Papageorgiou
Summary: This paper presents the methodology of a randomized controlled trial that aims to test the effectiveness of Attention Training Technique (ATT) as a stand-alone treatment for symptoms of anxiety and depression in patients with coronary heart disease (CHD). The study will also explore correlations between changes in psychological distress and C-Reactive protein (CRP).
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hannah M. Malian, Patrick J. Smith, Benson Hoffman, Wei Jiang, Katharine Ammerman, William E. Kraus, Alan Hinderliter, Andrew Sherwood, James A. Blumenthal
Summary: The study found that among anxious patients with diagnosed coronary heart disease, only higher baseline anxiety levels were associated with a reduction in anxiety following acute exercise. Other factors such as sex, severity of trait anxiety did not show significant differences in anxiety reduction.
JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION
(2021)
Article
Health Care Sciences & Services
Johanna M. van Dongen, Angela Jornada Ben, Aureliano P. Finch, Milou M. M. Rossenaar, Karolien E. M. Biesheuvel-Leliefeld, Adrie T. Apeldoorn, Raymond W. J. G. Ostelo, Maurits W. van Tulder, Harm W. J. van Marwijk, Judith E. Bosmans
Summary: The study demonstrates that the use of different EQ-5D country-specific value sets significantly impacts cost-utility outcomes. Country-specific QALY estimates differ significantly from that of the United Kingdom, and there are extensive differences in incremental cost-effectiveness ratios between countries.
Article
Medical Informatics
Elizabeth Ford, Natalie Edelman, Laura Somers, Duncan Shrewsbury, Marcela Lopez Levy, Harm van Marwijk, Vasa Curcin, Talya Porat
Summary: The study explored the factors influencing the adoption of CDSSs by GPs in the UK, identifying trust, usability, and situational context as key determinants. Recommendations included co-producing CDSSs with GPs for better fit within clinical workflow, ensuring accuracy and providing training to reduce alert fatigue and improve decision-support utilization.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2021)
Article
Psychiatry
S. E. M. van Dijk, A. D. Pols, M. C. Adriaanse, H. W. J. van Marwijk, M. W. van Tulder, J. E. Bosmans
Summary: The Step-Dep intervention is not cost-effective compared to usual care in a population of patients with DM2/CHD and subthreshold depression, so widespread implementation is not recommended.
Article
Psychology, Clinical
Nora Eilert, Ladislav Timulak, Daniel Duffy, Caroline Earley, Angel Enrique, Polly Kennedy, Clare McCormack, Jorge Palacios, Rebecca Wogan, Derek Richards
Summary: The study found that clients receiving internet-delivered CBT treatment learn and continue to effectively use a variety of CBT skills during and post-treatment. The results are consistent with similar research on face-to-face CBT and may help drive innovation and development in internet-delivered CBT interventions.
CLINICAL PSYCHOLOGY & PSYCHOTHERAPY
(2022)
Review
Medicine, General & Internal
Khulud Alharbi, Thomas Blakeman, Harm van Marwijk, David Reeves, Jung Yin Tsang
Summary: This study aimed to explore the enabling and constraining factors in the implementation of interventions for frail older persons in primary care. The results highlighted the importance of resource allocation, patient engagement, and professional skill sets in translating frailty interventions into practice. Recommendations included targeted allocation of resources for specific needs and earlier patient involvement to improve intervention implementation.
Article
Psychology, Clinical
Jorge E. Palacios, Angel Enrique, Olwyn Mooney, Simon Farrell, Caroline Earley, Daniel Duffy, Nora Eilert, Siobhan Harty, Ladislav Timulak, Derek Richards
Summary: This study investigates the rates of remission and relapse after completing acute phase of iCBT treatment in routine care setting. The results provide valuable insights into the durability of iCBT effects in routine care settings, where follow-up is not typically conducted after completion of treatment.
CLINICAL PSYCHOLOGY & PSYCHOTHERAPY
(2022)
Article
Computer Science, Cybernetics
Anja Thieme, Maryann Hanratty, Maria Lyons, Jorge Palacios, Rita Faia Marques, Cecily Morrison, Gavin Doherty
Summary: Recent advances in AI and machine learning have the potential to revolutionize healthcare delivery in the future. However, there is a need for more research and development in AI applications specific to healthcare contexts. This article presents a collaborative human-centered approach to developing an AI application that predicts treatment outcomes for patients receiving iCBT for depression and anxiety. By addressing the challenges of identifying clinically relevant AI applications and designing for sensitive contexts like mental health, the authors demonstrate how their approach integrates insights from both clinical practice and technical feasibility.
ACM TRANSACTIONS ON COMPUTER-HUMAN INTERACTION
(2023)
Review
Health Care Sciences & Services
Alexander Hodkinson, Evangelos Kontopantelis, Salwa S. Zghebi, Christos Grigoroglou, Brian McMillan, Harm van Marwijk, Peter Bower, Dialechti Tsimpida, Charles F. Emery, Mark R. Burge, Hunter Esmiol, Margaret E. Cupples, Mark A. Tully, Kaberi Dasgupta, Stella S. Daskalopoulou, Alexandra B. Cooke, Ayorinde F. Fayehun, Julie Houle, Paul Poirier, Thomas Yates, Joseph Henson, Derek R. Anderson, Elisabeth B. Grey, Maria Panagioti
Summary: In patients with cardiometabolic conditions, interventions using wearable trackers to improve steps per day mostly benefited older White men without multimorbidity.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Jorge Palacios, Adedeji Adegoke, Rebecca Wogan, Daniel Duffy, Caroline Earley, Nora Eilert, Angel Enrique, Sarah Sollesse, Judith Chapman, Derek Richards
Summary: This study compares the treatment effects of three low-intensity interventions for common mental disorders and finds that internet-delivered cognitive behavioural therapy shows the most significant improvements in depression, anxiety, and functioning.
BRITISH JOURNAL OF PSYCHOLOGY
(2023)
Review
Multidisciplinary Sciences
Sarah Partridge, Lisa Quadt, Monica Bolton, Jessica Eccles, Charlie Thompson, Alessandro Colasanti, Stephen Bremner, Christopher Iain Jones, Karin Due Bruun, Harm Van Marwijk
Summary: This article summarizes the evidence for the use of low dose naltrexone (LDN) in the treatment of fibromyalgia. The systematic literature review indicates that LDN may reduce pain and improve quality of life. Studies on LDN mechanisms suggest that ESR and inflammatory biomarkers may be involved. However, the current evidence from randomized controlled trials supporting the use of LDN in fibromyalgia patients is weak and further research is needed.
Article
Health Care Sciences & Services
Deborah Ikhile, Devyn Glass, Kat Frere-Smith, Sam Fraser, Keith Turner, Hasu Ramji, Georgie Gremesty, Elizabeth Ford, Harm van Marwijk
Summary: Co-production is recognized as a good way to facilitate collaboration among stakeholders, but it lacks a definitive model or clear understanding. This paper explores the reflections of researchers, practitioners, and advisors involved in a co-production exercise. The results highlight the importance of shared values and understanding, as well as shared power, responsibilities, and ownership in achieving positive outcomes.
HEALTH EXPECTATIONS
(2023)
Article
Health Care Sciences & Services
Diana Catalina Cumpanasoiu, Angel Enrique, Jorge E. Palacios, Daniel Duffy, Scott McNamara, Derek Richards
Summary: This study aimed to identify the trajectory of symptom change during internet-delivered cognitive behavioral therapy (iCBT) for depression and anxiety and investigate the patients' characteristics and platform use for each trajectory. The results showed that most patients benefited from treatment, but there were variations in patterns of improvement. Identifying predictors of nonresponse or early response can help tailor interventions and identify patients who are less likely to benefit from treatment.
JMIR MHEALTH AND UHEALTH
(2023)
Article
Public, Environmental & Occupational Health
Thomas Grice-Jackson, Imogen Rogers, Elizabeth Ford, Harm Van Marwijk, Catherine Topham, Geofrey Musinguzi, Hilde Bastiaens, Linda Gibson, Mark Bower, Papreen Nahar
Summary: The aim of this study was to understand the views, needs, and experiences of community members who would be involved in a community-based cardiovascular disease prevention intervention. The findings showed that participants were willing to engage in the intervention and highlighted the importance of sociocultural factors. Based on the findings, recommendations were made for intervention design, including a bottom-up approach, recruitment of skilled local volunteers, and emphasis on fun and simplicity.
HEALTH PROMOTION PRACTICE
(2023)
Article
Psychiatry
Noortje P. Janssen, Peter Lucassen, Marcus J. H. Huibers, David Ekers, Theo Broekman, Judith E. Bosmans, Harm Van Marwijk, Jan Spijker, Richard Oude Voshaar, Gert-Jan Hendriks
Summary: This study evaluated the effectiveness of behavioural activation (BA) by mental health nurses (MHNs) for depressed older adults in primary care. The results showed that BA was more effective than treatment as usual (TAU) in reducing depressive symptoms at post-treatment and 3-month follow-up, but not at 6- to 12-month follow-up.
PSYCHOTHERAPY AND PSYCHOSOMATICS
(2023)
Article
Cardiac & Cardiovascular Systems
Salwa S. Zghebi, Mamas A. Mamas, Darren M. Ashcroft, Martin K. Rutter, Harm VanMarwijk, Chris Salisbury, Christian D. Mallen, Caroline A. Chew-Graham, Nadeem Qureshi, Stephen F. Weng, Tim Holt, Iain Buchan, Niels Peek, Sally Giles, David Reeves, Evangelos Kontopantelis
Summary: This study developed and validated a CVD severity score for coronary heart disease (CHD) patients, finding that higher severity scores were associated with increased risks of hospitalisation and mortality.
Article
Psychiatry
Xiuxiu Zhao, Junlin Li, Xianhai Xie, Zhaojing Fang, Yue Feng, Yi Zhong, Chen Chen, Kaizong Huang, Chun Ge, Hongwei Shi, Yanna Si, Jianjun Zou
Summary: This study developed dynamic prediction models for postoperative delirium (POD) after cardiac surgery using machine learning algorithms. The models showed satisfactory predictive performance and were used to create online risk calculators for identifying high-risk patients and facilitating early intervention or care.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2024)
Article
Psychiatry
Miaolan Guo, Jing Su, Shaoyan Zheng, Baixin Chen
Summary: Psoriasis is associated with poor sleep quality and higher risk for sleep disturbance, especially among patients with psoriatic arthritis, severe psoriasis, shorter duration of psoriasis, and younger age. Patients with psoriasis are also more likely to experience insomnia, restless legs syndrome (RLS), and depression.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2024)