Article
Environmental Sciences
Mang Sun, Xining Cao, Yuhao Wu, Lianju Shen, Guanghui Wei
Summary: Prenatal exposure to organochlorines and PFAS may be associated with lower neonatal TT4 levels.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Xiyuan Yao, Yidong Wang, Yifei Ma, Mengmeng Fu, Huimin Wang, Deliang Tang, Jisheng Nie
Summary: We investigated the link between maternal urinary polycyclic aromatic hydrocarbon (PAH) metabolites and thyroid hormones in 120 pairs of pregnant women and newborns. PAH metabolites were measured through high-performance liquid chromatography with tandem mass spectrometry, while thyroid hormones were measured using a flow fluorescence assay. The study found that there was a negative impact of total OH PAHs in maternal urine on triiodothyronine (T3) levels. The results also showed associations between maternal urinary PAH metabolites and thyroid hormones in umbilical cord blood plasma, suggesting that prenatal exposure to PAHs may disrupt neonatal thyroid function.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Chenhui Yang, Jing Fang, Xiaojie Sun, Wenxin Zhang, Juxiao Li, Xiaomei Chen, Ling Yu, Wei Xia, Shunqing Xu, Zongwei Cai, Yuanyuan Li
Summary: The study found that prenatal exposure to beta-HCH was associated with increased BMI z-score and higher risk of overweight status in infants, especially at 12 and 24 months of age, with stronger effects observed in girls. Other OCPs did not show significant relationships with infant growth.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Zorimar Rivera-Nunez, Carolyn W. Kinkade, Leena Khoury, Jessica Brunner, Hannah Murphy, Christina Wang, Kurunthachalam Kannan, Richard K. Miller, Thomas G. O'Connor, Emily S. Barrett
Summary: The study found that maternal serum levels of poly- and perfluoroalkyl substances (PFAS) are associated with sex steroid hormone levels during pregnancy. Specifically, PFHxS is associated with increased testosterone levels in male fetuses, while PFNA and PFDA are associated with increased free testosterone levels in male fetuses. For female fetuses, PFHxS is associated with increased levels of estradiol and estriol. No associations were found for PFOS and PFOA.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Brendan Bos, Ben Barratt, Dafnis Batalle, Oliver Gale-Grant, Emer J. Hughes, Sean Beevers, Lucilio Cordero-Grande, Anthony N. Price, Jana Hutter, Joseph V. Hajnal, Frank J. Kelly, David Edwards, Serena J. Counsell
Summary: The study suggests that prenatal exposure to air pollution is associated with altered brain development in newborns. Specifically, higher exposure to PM10 and lower exposure to NO2 are linked to changes in ventricular volume and cerebellum size. These findings highlight the importance of reducing maternal exposure to particulate matter during pregnancy.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Zorimar Rivera-Nunez, Megan Hansel, Camila Capurro, Danielle Kozlosky, Christina Wang, Cathleen L. Doherty, Brian Buckley, Pamela Ohman-Strickland, Richard K. Miller, Thomas G. O'Connor, Lauren M. Aleksunes, Emily S. Barrett
Summary: This study found that cadmium exposure during pregnancy may lead to lower testosterone levels in pregnant women, while estrogen levels remain unchanged. This effect may be stronger in pregnancies carrying female fetuses. Further research is needed to understand how alterations in gestational testosterone activity may impact pregnancy and child health.
Article
Endocrinology & Metabolism
Mengmeng Yang, Man Sun, Chenyu Jiang, Qianqian Wu, Ying Jiang, Jian Xu, Qiong Luo
Summary: This study investigated the effects of thyroid hormones and carnitine on neonate birth weight, and found that routine examination of C0 and thyroid hormones during the second trimester has a positive effect on the intervention of birth weight.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Environmental Sciences
Shengju Yin, Ying Sun, Jinhui Yu, Zaiming Su, Mingkun Tong, Yali Zhang, Jufen Liu, Linlin Wang, Zhiwen Li, Aiguo Ren, Lei Jin
Summary: Neural tube defects (NTDs) are associated with prenatal exposure to organochlorine pesticides (OCPs), with specific OCPs showing significant correlation with increased NTD risk. Additionally, there is a linear relationship between the concentration of OCPs mixture and NTD risk, indicating a joint effect on NTD risk.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Tina Kold Jensen, Anna-Maria Andersson, Katharina M. Main, Trine Holm Johannsen, Marianne S. Andersen, Henriette Boye Kyhl, Anders Juul, Hanne Frederiksen
Summary: The study found that maternal exposure to parabens was associated with reproductive hormone levels and anogenital distance in male and female infants, with greater effects observed in girls and inconsistent effects in boys. This suggests potential endocrine-disrupting effects of parabens on human development, particularly in vulnerable periods.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Dan Ma, Chaitra Badve, Jessie E. P. Sun, Siyuan Hu, Xiaofeng Wang, Yong Chen, Ameya Nayate, Michael Wien, Douglas Martin, Lynn T. T. Singer, Jared C. C. Durieux, Chris Flask, Deanne Wilson Costello
Summary: This study aimed to investigate whether MR fingerprinting (MRF) scans can provide motion-robust and quantitative brain tissue measurements for non-sedated infants with prenatal opioid exposure (POE). The image quality of MRF and MRI was assessed and compared, and the T1 and T2 values of different age groups were analyzed. The results showed that MRF images had significantly higher quality ratings in all three feature types compared to MRI images. Therefore, MR fingerprinting has the potential to be a motion-robust and efficient method for nonsedated infants.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Environmental Sciences
Ju Wang, Lu-Lu Cao, Zhen-Yan Gao, Hong Zhang, Jun-Xia Liu, Su-Su Wang, Hui Pan, Chong-Huai Yan
Summary: This study investigated the associations of prenatal exposure to a mixture of OCPs, Hg, DHA, EPA and Se with thyroid hormone parameters in newborns, revealing dose-response relationships between mixture components and outcomes, but overall effects were not significant. The results suggest that prenatal exposure to p,p'-DDE, HCB and EPA as part of a mixture might affect thyroid function of newborns in independent and interactive ways, warranting further investigation into potential biological mechanisms.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Katerina Margetaki, Marina Vafeiadi, Mariza Kampouri, Theano Roumeliotaki, Polyxeni Karakosta, Vasiliki Daraki, Manolis Kogevinas, Howard Hu, Maria Kippler, Leda Chatzi
Summary: Maintaining thyroid homeostasis during pregnancy is crucial for fetal development. Studies have shown that exposure to toxic metals, particularly high concentrations of cadmium, antimony, and lead, can significantly affect thyroid hormone levels. Simultaneous exposure to multiple toxic metals may also have a synergistic interaction, exacerbating the effects on thyroid function.
ENVIRONMENTAL POLLUTION
(2021)
Article
Biochemistry & Molecular Biology
Teresa Peluso, Valeria Nittoli, Carla Reale, Immacolata Porreca, Filomena Russo, Luca Roberto, Antonia Giacco, Elena Silvestri, Massimo Mallardo, Mario De Felice, Concetta Ambrosino
Summary: Early life exposure to Endocrine Disruptor Chemicals (EDCs), such as the pesticide Chlorpyrifos (CPF), has been found to affect thyroid activity, glucose metabolism, and lipid metabolism. In this study, the researchers investigated the effects of CPF exposure on the metabolism and signaling of thyroid hormones (THs) and lipid/glucose metabolism in mice. They found that these processes were altered in males that were exposed to CPF, leading to hypothyroidism and systemic hyperglycemia. Additionally, the researchers discovered that CPF affected glucose metabolism and TH levels through the modulation of FOXO1 activity in liver cells. These findings highlight the importance of considering the intergenerational and sex-specific effects of CPF exposure on metabolic homeostasis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Qian Yao, Angela Vinturache, Xiaoning Lei, Zixia Wang, Chengyu Pan, Rong Shi, Tao Yuan, Yu Gao, Ying Tian
Summary: This study found potential associations between prenatal PFAS exposure and early neurodevelopmental deficiencies, particularly in the gross motor domain. The associations were partly explained by thyroid hormone mediator effects.
ENVIRONMENTAL RESEARCH
(2022)
Article
Oncology
William C. Strohsnitter, Marianne Hyer, Kimberly A. Bertrand, Andrea L. Cheville, Julie R. Palmer, Elizabeth E. Hatch, Kjersti M. Aagaard, Linda Titus, Iris L. Romero, Dezheng Huo, Robert N. Hoover, Rebecca Troisi
Summary: A study on the influence of prenatal diethylstilbestrol (DES) exposure on cancer incidence among middle-aged men showed that there was no increase in overall or prostate cancer rates among men prenatally DES-exposed, but a reduction in urinary tract cancer risk was observed. These findings suggest that prenatal DES exposure is unlikely to significantly impact cancer development in middle-aged men.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Psychiatry
Bahar Azemati, Ramin Heshmat, Mostafa Qorbani, Zeinab Ahadi, Ali Azemati, Gita Shafiee, Hasan Ziaodini, Mohammad Esmail Motlagh, Roya Kelishadi
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2020)
Review
Food Science & Technology
Maryam Bahreynian, Awat Feizi, Roya Kelishadi
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2020)
Article
Peripheral Vascular Disease
Maryam Yazdi, Farahnak Assadi, Seyed S. Daniali, Ramin Heshmat, Mehryar Mehrkash, Mohammad E. Motlagh, Mostafa Qorbani, Roya Kelishadi
JOURNAL OF CLINICAL HYPERTENSION
(2020)
Article
Biochemistry & Molecular Biology
Shoresh Barkhordari, Omid Mirmosayyeb, Marjan Mansourian, Fahimeh Hosseininasab, Saba Ramezani, Mahdi Barzegar, Mohammad Mehdi Amin, Parinaz Poursafa, Nafiseh Esmaeil, Roya Kelishadi
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
(2020)
Review
Pediatrics
Zeinab Hemati, Mojtaba Keikha, Roya Riahi, Seyede Shahrbanoo Daniali, Masoumeh Goudarzi, Roya Kelishadi
Summary: This systematic review suggests that individuals born in cold season may have higher BMI and weight in childhood, and birth month may have an impact on weight and BMI in boys. However, there is no clear association between season/month of birth and birth weight. Further research should focus on identifying the impact of confounding factors such as vitamin D status in the pathway of this association.
PEDIATRIC RESEARCH
(2021)
Article
Biodiversity Conservation
Saeid Fadaei, Hamidreza Pourzamani, Karim Ebrahimpour, Awat Feizi, Seyede Shahrbanoo Daniali, Roya Kelishadi
Summary: The study evaluated urinary parabens concentration among 117 Iranian pregnant women in their first trimester. Methylparaben, ethylparaben, propylparaben, and butylparaben were detected with certain median concentrations, and significant associations were found with variables such as educational level, plastic packaging, physical activity, sampling season, and use of personal care products. This suggests that Iranian pregnant women are at high risk of paraben exposure.
HUMAN AND ECOLOGICAL RISK ASSESSMENT
(2021)
Article
Immunology
Piotr Rzymski, Carlos A. Camargo, Andrzej Fal, Robert Flisiak, Willis Gwenzi, Roya Kelishadi, Alexander Leemans, Juan J. Nieto, Ahmet Ozen, Matjaz Perc, Barbara Poniedzialek, Constantine Sedikides, Frank Sellke, Emilia C. Skirmuntt, Anzhela Stashchak, Nima Rezaei
Summary: Pursuing COVID-19 vaccinations is crucial to controlling the pandemic and bringing hope for global health. Despite challenges such as shortages, inequity, and immunity durability concerns, booster doses of vaccines are essential. Balancing immunity optimization in wealthy populations with addressing vaccine availability issues in low-income regions is critical.
Article
Psychiatry
Zahra Aslani, Maryam Bahreynian, Nazli Namazi, Nitin Shivappa, James R. Hebert, Hamid Asayesh, Mohammad Esmaeil Motlagh, Mohammad Ali Pourmirzaei, Amir Kasaeian, Armita Mahdavi-Gorabi, Mostafa Qorbani, Roya Kelishadi
Summary: This study aimed to examine the association between dietary acid load (DAL) and anthropometric indices in Iranian children and adolescents. The findings revealed a direct association between diet-induced acid load and neck circumference, as well as an inverse association between DAL indices and parental BMI. Further well-designed clinical studies are needed to confirm these results and explore the underlying mechanisms.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2021)
Article
Psychiatry
Hanieh-Sadat Ejtahed, Zohreh Mahmoodi, Mostafa Qorbani, Pooneh Angoorani, Mohammad Esmaeil Motlagh, Shirin Hasani-Ranjbar, Hasan Ziaodini, Majzoubeh Taheri, Ramin Heshmat, Roya Kelishadi
Summary: This study found a stronger association between waist circumference and continuous metabolic syndrome risk score components compared to body mass index in school-aged children, emphasizing the need for more attention to central obesity during childhood.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2021)
Review
Information Science & Library Science
Azra Daei, Mohammad Reza Soleymani, Hasan Ashrafi-rizi, Roya Kelishadi, Ali Zargham-Boroujeni
Summary: This review identified personal, technical, and organizational facilitators in physicians' information-seeking behavior during patient care. Factors such as internet utilization, information searching skills, available time, personal interests, and knowing preferred sites or textbooks were found to promote clinical information-seeking behavior among doctors. Technical factors such as navigation support, ease of searching, and finding needed information also played a crucial role, along with organizational factors like proximity to internet facilities and access during consultations.
HEALTH INFORMATION AND LIBRARIES JOURNAL
(2021)
Article
Public, Environmental & Occupational Health
Zahra Esfandiari, Maryam Mirlohi, Jila M. Tanha, Marjan Hadian, Sayed Isa Mossavi, Akbar Ansariyan, Neda Ghassami, Shahnaz Adib, Tahereh Bahraini, Leila Safaeian, Farzaneh Pakmehr, Farnaz Mashhadian, Maryam Abolhasani, Mohammad Reza Marasi, Fatemeh Isteki, Roya Abedi, Parvin Ghorbani, Parisa Shoaei, Roya Kelishadi
Summary: This study showed that education through face-to-face sessions had a positive impact on the knowledge, attitudes, and practices of the respondents towards Traffic Light (TL) food labeling. The intervention resulted in significant improvements in scores before and after education, demonstrating the effectiveness of targeted education in promoting healthier food choices.
INTERNATIONAL QUARTERLY OF COMMUNITY HEALTH EDUCATION
(2021)
Meeting Abstract
Clinical Neurology
Negin Badihian, Shervin Badihian, Seyede Shahrbanoo Daniali, Roya Kelishadi
Article
Psychiatry
Kumars Pourrostami, Ramin Heshmat, Zeinab Hemati, Motahar Heidari-Beni, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Alireza Raeisi, Gita Shafiee, Hasan Ziaodini, Shagayegh Beshtar, Majzoubeh Taheri, Armita Mahdavi-Gorabi, Tahereh Aminaei, Roya Kelishadi
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2020)
Review
Medicine, General & Internal
Mehri Khoshhali, Mohammad Mehdi Amin, Ali Fatehizadeh, Afshin Ebrahimi, Ensiyeh Taheri, Roya Kelishadi
JOURNAL OF RESEARCH IN MEDICAL SCIENCES
(2020)
Review
Pediatrics
Maryam Bahreynian, Marjan Mansourian, Nafiseh Mozaffarian, Parinaz Poursafa, Mehri Khoshhali, Roya Kelishadi
JOURNAL OF PEDIATRICS REVIEW
(2020)