Article
Neuroimaging
Mohamed M. Salem, Brian T. Jankowitz, Jan-Karl Burkhardt, Lori Lyn Price, Osama O. Zaidat
Summary: This study compared the outcome of using different devices for treating wide necked aneurysms. The Neuroform Atlas showed higher occlusion rates compared to LVIS and WEB devices, while LVIS and WEB devices had similar retreatment rates.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Neuroimaging
Brian T. Jankowitz, Ashutosh P. Jadhav, Bradley Gross, Tudor G. Jovin, Abdulnasser A. Alhajeri, Justin F. Fraser, Ricardo A. Hanel, Eric Sauvageau, Amin Aghaebrahim, Donald Frei, Richard Bellon, David Loy, Ajit S. Puri, Adel M. Malek, Ajith Thomas, Gabor Toth, Demetrius Klee Lopes, R. Webster Crowley, Adam S. Arthur, John Reavey-Cantwell, Eugene Lin, Adnan H. Siddiqui, Michael J. Alexander, Ahmad Khaldi, Geoffrey P. Colby, Justin M. Caplan, Sudhakar R. Satti, Aquilla S. Turk, Alejandro M. Spiotta, Richard Klucznik, Danial K. Hallam, David Kung, Michael T. Froehler, R. Charles Callison, Peter Kan, Steven W. Hetts, Osama O. Zaidat
Summary: The ATLAS trial in patients with posterior circulation aneurysms demonstrated high rates of technical efficacy and safety performance, achieving the primary effectiveness and safety endpoints. The results showed that the Neuroform Atlas Stent System with adjunctive coiling had a good technical success rate and high safety performance in patients with wide-necked posterior circulation aneurysms.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
Ho Jun Yi, Dong-Seong Shin, Bum-Tae Kim, Dong Hoon Lee, Jae Hoon Sung
Summary: The safety and efficacy of SAC using Neuroform Atlas for treating RIA were assessed compared with coiling alone through propensity score matching analysis. The SAC using Neuroform Atlas group showed higher complete occlusion rate, lower recanalization rate, and lesser need for retreatment compared with the coiling-alone group.
Article
Neuroimaging
Justin R. Mascitelli, Michael R. Levitt, Christoph J. Griessenauer, Louis J. Kim, Bradley Gross, Adib Abla, Ethan Winkler, Brian Jankowitz, Ramesh Grandhi, Oded Goren, Clemens M. Schirmer
Summary: The multicenter experience using the transcirculation approach for stent-assisted coiling of intracranial aneurysms showed low complication rates and good clinical outcomes, demonstrating its effectiveness for a variety of aneurysms.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2021)
Article
Clinical Neurology
Eung Koo Yeon, Young Dae Cho, Dong Hyun Yoo, Jeong Eun Kim, Kang Min Kim, Sung Ho Lee, Won-Sang Cho, Hyun-Seung Kang
Summary: Midterm outcomes of stent-assisted coil embolization with LVIS and Atlas devices were similar, despite the theory of LVIS superiority. Further randomized comparative studies are needed to confirm these findings.
Article
Neuroimaging
Ricardo A. Hanel, Gustavo M. Cortez, Brian T. Jankowitz, Eric Sauvageau, Amin Aghaebrahim, Eugene Lin, Ashutosh P. Jadhav, Bradley Gross, Ahmad Khaldi, Rishi Gupta, Donald Frei, David Loy, Lori Lyn Price, Steven W. Hetts, Osama O. Zaidat
Summary: This study compared the efficacy and safety outcomes of the Neuroform Atlas Stent System for intracranial aneurysms in different locations. The results suggest that the system is a safe and effective treatment modality regardless of aneurysm location.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Clinical Neurology
David C. Lauzier, Brandon K. Root, Arindam R. Chatterjee, Joshua W. Osbun, Christopher J. Moran, Akash P. Kansagra
Summary: The type of the first stent does not significantly influence the need for subsequent Y-stenting in stent-assisted coiling of wide neck bifurcation aneurysms in the anterior communicating segment and basilar tip region. A larger cohort may reveal differences between these two stents in aneurysms with large neck sizes.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2023)
Article
Clinical Neurology
Philipp Dietrich, Alica Gravius, Ruben Muehl-Benninghaus, Umut Yilmaz, Michael Kettner, Hagen Bomberg, Wolfgang Reith, Andreas Simgen
Summary: The study evaluated the clinical and angiographic outcomes of patients with complex intracranial aneurysms treated with ACCLINO (R) and ACCLINO (R) flex stents. The results showed no significant difference between the initial and follow-up angiographic outcomes of the two stent systems, leading to satisfactory treatment results.
CLINICAL NEURORADIOLOGY
(2021)
Article
Clinical Neurology
Ahmed Kashkoush, Mohamed E. El-Abtah, Shaarada Srivatsa, Ansh Desai, Mark Davison, Rebecca Achey, Ashutosh Mahapatra, Thomas Patterson, Nina Moore, Mark Bain
Summary: This study aims to compare the effects of Woven EndoBridge (WEB) and stent-assisted coiling (SAC) on wide-neck bifurcation intracranial aneurysms (WNBAs). The mid-term complete and adequate occlusion rates were similar between the two groups, suggesting equipoise in treatment options for WNBAs.
JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Zhe Ji, Wanxin Yang, Yongjie Ma, Lisong Bian, Guilin Li, Yongjuan Fu, Yueshan Piao, Hongqi Zhang
Summary: Vertebrobasilar dolichoectasia (VBD) is a rare cerebrovascular disorder with high morbidity and mortality rates. The fragmented internal elastic lamina and multiple dissections make VBD difficult to treat. Stent-assisted coil embolization is a main treatment modality, but the healing duration and evaluation of endothelial coverage remain uncertain. We present an autopsy case of late in-stent thrombosis and review the literature to provide reference for endovascular treatment and antiplatelet regimen of VBD.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Yeon Soo Choo, Eun-Joo Kim, Sang-Min Sung, Lee Hwangbo, Tae-Hong Lee, Jun Kyeung Ko
Summary: In this study, the efficacy and safety of additional rescue stenting (ARS) with Neuroform Atlas stent (NAS) in the endovascular treatment of cerebral aneurysms were evaluated. The results showed good technical safety and favorable clinical and angiographic outcomes. However, delayed in-stent stenosis was not uncommon, highlighting the need for regular imaging follow-up.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2023)
Article
Neuroimaging
Stefan Wanderer, Basil Erwin Gruter, Gwendoline Boillat, Sivani Sivanrupan, Jeannine Rey, Kristina Catalano, Michael VonGunten, Hans Rudolf Widmer, Lukas Andereggen, Serge Marbacher
Summary: This study investigates the origin of endothelial cells in the neointima of endovascular treated aneurysms and found that cell migration forming a neointima seemed mainly dependent on the adjacent vessel.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Clinical Neurology
Taichi Ishiguro, Akitsugu Kawashima, Shunsuke Nomura, Kenichi Hodotsuka, Atsushi Kuwano, Yukiko Tanaka, Masato Murakami, Takakazu Kawamata
Summary: Accessing the PCA via EC-IC bypass grafts and deploying a horizontal stent across the neck of BAA for coil embolization is a safe and effective treatment strategy for large, wide-necked aneurysms.
ACTA NEUROCHIRURGICA
(2022)
Review
Surgery
Lorenzo Gibello, Gianfranco Varetto, Vittorio Pasta, Matteo Ripepi, Andrea Discalzi, Fabio Verzini
Summary: This article presents the results of an unconventional endovascular treatment for a large (65 mm) saccular visceral aortic aneurysm in a 78-year-old patient who was deemed unfit for open surgery. The treatment involved the deployment of an aortic stent and embolization of the aneurysm sac using coils. The study concludes that this technique can be considered as an alternative when traditional treatments are not feasible. Rating: 8/10.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Review
Medicine, General & Internal
Jia-Lin Xia, Guang-Lei Li, Hong-En Liu, Xia Feng-Fei, Xin-Dong Gu
Summary: For the treatment of unruptured intracranial aneurysms (IAs), flow-diverting devices (FDDs) show a relatively higher complete occlusion rate, especially in patients with large or giant IAs. However, for patients with non-large/giant IAs, there is no significant difference in treatment effects between FDD and coil embolization (CE). The retreatment and complication rates are similar between the two treatment methods, but CE treatment has a higher rate of parent artery patency.
Article
Clinical Neurology
Andrey Petrov, Ganbaatar Rentsenkhuu, Baatarjan Nota, Erdenebat Ganzorig, Boldbat Regzengombo, Sara Jagusch, Elina Henkes, Hans Henkes
Summary: The study evaluated the safety and efficacy of p64MW HPC in Mongolian patients under dual antiplatelet therapy. The results showed a low procedural complication rate and high early aneurysm occlusion rate with p64MW HPC implantation under dual antiplatelet therapy.
INTERVENTIONAL NEURORADIOLOGY
(2021)
Editorial Material
Clinical Neurology
Victoria Hellstern, Marta Aguilar-Perez, Maike Dukiewicz, Gottlieb Maier, Hansjoerg Baezner, Hans Henkes
CLINICAL NEURORADIOLOGY
(2021)
Article
Clinical Neurology
Marta Aguilar Perez, Elina Henkes, Victoria Hellstern, Carmen Serna Candel, Christina Wendl, Hansjoerg Baezner, Oliver Ganslandt, Hans Henkes
Summary: The use of p64 for the treatment of intracranial saccular unruptured aneurysms from the anterior circulation is a safe and effective option, showing a high rate of occlusion in long-term follow-ups with low morbimortality.
OPERATIVE NEUROSURGERY
(2021)
Review
Clinical Neurology
William Crinnion, Pervinder Bhogal, Hegoda Levansri Dilrukshan Makalanda, Ken Wong, Adam Arthur, Christophe Cognard, Hans Henkes, Dave Fiorella, Laurent Pierot
Summary: The Woven Endobridge (WEB) device has shown to be safe and effective for treating wide necked bifurcation aneurysms in multiple prospective studies, although primarily focusing on unruptured aneurysms. This review aims to summarize the current evidence available on using WEB for treating ruptured aneurysms.
INTERVENTIONAL NEURORADIOLOGY
(2021)
Article
Clinical Neurology
Pervinder Bhogal, Andrey Petrov, Ganbaatar Rentsenkhu, Baatarjan Nota, Erdenebat Ganzorig, Boldbat Regzengombo, Sara Jagusch, Elina Henkes, Hans Henkes
Summary: The study evaluated the safety and efficacy of using p64MW HPC and p48MW HPC flow diverters in Mongolian patients under single antiplatelet therapy (SAPT). The results showed that patients treated with coated flow diverters under SAPT demonstrated good occlusion rates and low complication rates.
INTERVENTIONAL NEURORADIOLOGY
(2022)
Article
Medicine, General & Internal
Marta Aguilar Perez, Hans Henkes, Wiebke Kurre, Carlos Bleise, Pedro Nicolas Lylyk, Javier Lundquist, Francis Turjman, Hanan Alhazmi, Christian Loehr, Stephan Felber, Hannes Deutschmann, Stephan Lowens, Luigi Delehaye, Markus Moehlenbruch, Joerg Hattingen, Pedro Lylyk
Summary: Coil embolization is a well-established treatment for intracranial aneurysms, but wide-neck bifurcation aneurysms (WNBAs) remain challenging. The pCONUS, a stent-like implant, has shown to be a safe and effective option for the treatment of WNBAs, with acceptable rates of aneurysm occlusion and low risks of adverse neurologic events.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Ali Khanafer, Alexandru Cimpoca, Paul Bhogal, Oksana Babiy-Pachomow, Peter Kurucz, Oliver Ganslandt, Hans Henkes
Summary: This study retrospectively evaluated the use of Prasugrel as single antiplatelet therapy in open surgical procedures and found that it did not lead to excessive intraoperative and postoperative hemorrhage in neurovascular surgeries.
JOURNAL OF NEURORADIOLOGY
(2023)
Article
Medicine, General & Internal
Kamran Hajiyev, Victoria Hellstern, Alexandru Cimpoca, Christina Wendl, Hansjorg Baezner, Hans Henkes, Philipp von Gottberg
Summary: The in-hospital outcomes of 1158 patients undergoing carotid artery stenting (CAS) at a single neurovascular center were evaluated, confirming the procedure's excellent safety profile with a low rate of complications.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Philipp Buecke, Victoria Hellstern, Alexandru Cimpoca, Jose E. Cohen, Thomas Horvath, Oliver Ganslandt, Hansjoerg Baezner, Hans Henkes
Summary: This systematic review examines the use of endovascular treatment (EVT) for cerebral venous sinus/vein thromboses (SVT), focusing on patient selection, treatment strategies, and the impact of the COVID-19 pandemic. The study found that EVT was feasible and safe in a highly selected patient cohort, but did not lead to increased favorable functional outcomes according to randomized controlled trial (RCT) data. However, observational data showed frequent good functional outcomes despite an anticipated poor prognosis. Further research is needed to identify high-risk patients, determine optimal methods and devices, and establish best timing for treatment initiation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Ali Khanafer, Pervinder Bhogal, Victoria Hellstern, Christoph Harmening, Hansjoerg Baezner, Oliver Ganslandt, Hans Henkes
Summary: This study analyzed the diagnosis and management of patients with aneurysmal subarachnoid hemorrhage who died from ischemic brain damage caused by vasospasm. It was found that early recognition of severe vasospasm is crucial for treatment, but aggressive treatment may not prevent death.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Georg Gihr, Diana Horvath-Rizea, Patricia Kohlhof-Meinecke, Oliver Ganslandt, Hans Henkes, Wolfgang Haertig, Aneta Donitza, Martin Skalej, Stefan Schob
Summary: This study investigated the potential of diffusion weighted imaging (DWI) using a radiomic approach to provide complementary information for tumor differentiation and cell proliferation, as well as the underlying genetic and epigenetic tumor profile. The researchers found several histogram features that could assist in presurgical tumor grading and potentially provide insights into tumor characteristics on a cellular and subcellular scale.
Editorial Material
Cardiac & Cardiovascular Systems
Hans Henkes, Ali Khanafer, Alexandru Cimpoca
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Review
Medicine, General & Internal
Sebastian Johannes Mueller, Elina Henkes, Matthew J. Gounis, Stephan Felber, Oliver Ganslandt, Hans Henkes
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Marcel Alfter, Pablo Albina-Palmarola, Alexandru Cimpoca, Roberto Diaz-Peregrino, Paul Jans, Oliver Ganslandt, Dietmar Kuehne, Hans Henkes
Summary: This study reports the experience of two centers in treating high-grade brain AVMs using a multi-stage approach. Age >80 years and poor baseline neurological condition were associated with poor outcomes. The devascularization percentage did not affect the results.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Clinical Neurology
Keng Siang Lee, Cheyenne Lee, Permesh S. Dhillon, Ramez Kirollos, Vincent D. W. Nga, Tseng Tsai Yeo, Hans Henkes, Adam S. Arthur, Leonard L. L. Yeo, Pervinder Bhogal
Summary: Antiplatelet therapy (AT) may help reduce the pro-coagulant state in the cerebral circulation caused by aneurysmal subarachnoid hemorrhage (aSAH). This meta-analysis study showed that AT is associated with lower rates of delayed cerebral ischemia, symptomatic vasospasm, and moderate/severe angiographic vasospasm, without increasing the risk of hemorrhagic events.
NEUROSURGICAL REVIEW
(2023)