☆ 4.6 Article

Emerging threats from zoonotic coronaviruses-from SARS and MERS to 2019-nCoV

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2020)

期刊

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

卷 53, 期 3, 页码 365-367

出版社

ELSEVIER TAIWAN

DOI: 10.1016/j.jmii.2020.02.001

关键词

-

类别

Immunology Infectious Diseases Microbiology

向作者/读者索取更多资源

Protocol

Reagent

作者

我是这篇论文的作者

点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6

评分不足

次要评分

新颖性

-

重要性

-

科学严谨性

-

评价这篇论文

推荐

Article Multidisciplinary Sciences

Phenotypic and genetic characterization of MERS coronaviruses from Africa to understand their zoonotic potential

Ziqi Zhou, Kenrie P. Y. Hui, Ray T. Y. So, Huibin Lv, Ranawaka A. P. M. Perera, Daniel K. W. Chu, Esayas Gelaye, Harry Oyas, Obadiah Njagi, Takele Abayneh, Wilson Kuria, Elias Walelign, Rinah Wanglia, Ihab El Masry, Sophie Von Dobschuetz, Wantanee Kalpravidh, Veronique Chevalier, Eve Miguel, Ouafaa Fassi-Fihri, Amadou Trarore, Weiwen Liang, Yanqun Wang, John M. Nicholls, Jincun Zhao, Michael C. W. Chan, Leo L. M. Poon, Chris Ka Pun Mok, Malik Peiris

Summary: The study revealed that coronaviruses from Africa have lower replication competence, leading to reduced virus activity in human lung cell cultures and experimentally infected mouse lungs. Additionally, the spike protein of African subtype viruses was associated with decreased virus entry into respiratory cells, resulting in lower virus replication competence in vitro and in vivo.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

添加到收藏夹

Article Virology

A Novel Frameshifting Inhibitor Having Antiviral Activity against Zoonotic Coronaviruses

Dae-Gyun Ahn, Gun Young Yoon, Sunhee Lee, Keun Bon Ku, Chonsaeng Kim, Kyun-Do Kim, Young-Chan Kwon, Geon-Woo Kim, Bum-Tae Kim, Seong-Jun Kim

Summary: Recent outbreaks of zoonotic coronaviruses, such as MERS-CoV and SARS-CoV-2, have caused significant casualties and economic shock. A novel compound, KCB261770, has been identified to effectively inhibit MERS-CoV frameshifting, showing potential as a drug candidate for interfering with pan-coronavirus frameshifting.

VIRUSES-BASEL (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice

Alexander A. Cohen, Priyanthi N. P. Gnanapragasam, Yu E. Lee, Pauline R. Hoffman, Susan Ou, Leesa M. Kakutani, Jennifer R. Keeffe, Hung-Jen Wu, Mark Howarth, Anthony P. West, Christopher O. Barnes, Michel C. Nussenzweig, Pamela J. Bjorkman

Summary: The study developed nanoparticles displaying the receptor binding domain (RBD) of SARS-CoV-2 and other animal coronaviruses, which induced cross-reactive antibody responses in mice. Immunization with mosaic RBD nanoparticles resulted in superior neutralization of heterologous viruses, providing a potential strategy for simultaneous protection against multiple coronaviruses.

SCIENCE (2021)

添加到收藏夹

Review Cell Biology

Emerging viruses: Cross-species transmission of coronaviruses, filoviruses, henipaviruses, and rotaviruses from bats

Jin Tian, Jiumeng Sun, Dongyan Li, Ningning Wang, Lifang Wang, Chang Zhang, Xiaorong Meng, Xiang Ji, Marc A. Suchard, Xu Zhang, Alexander Lai, Shuo Su, Michael Veit

Summary: This article mainly introduces the taxonomy, geographic distribution, and unique traits of bats as virus reservoirs, as well as the origin, intermediate hosts, and interspecies transmission mechanisms of Middle East respiratory syndrome coronavirus, severe acute respiratory syndrome coronavirus, SARS-CoV-2, and other viruses associated with bats. The molecular interactions between viral surface proteins and host cell receptors are also studied, comparing these interactions in humans, intermediate hosts, and bats.

CELL REPORTS (2022)

添加到收藏夹

Article Immunology

A Yellow Fever 17D Virus Replicon-Based Vaccine Platform for Emerging Coronaviruses

Nadia Oreshkova, Sebenzile K. Myeni, Niraj Mishra, Irina C. Albulescu, Tim J. Dalebout, Eric J. Snijder, Peter J. Bredenbeek, Kai Dallmeier, Marjolein Kikkert

Summary: The study successfully generated a novel vaccine platform by inserting subunits from three different betacoronaviruses into the yellow fever virus 17D vaccine, which elicited good immune responses in mice. These YF17D replicon-based vaccines could be a promising and safe option for current and future emerging coronaviruses.

VACCINES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

The human pandemic coronaviruses on the show: The spike glycoprotein as the main actor in the coronaviruses play

Pedro F. N. Souza, Felipe P. Mesquita, Jackson L. Amaral, Patricia G. C. Landim, Karollyny R. P. Lima, Marilia B. Costa, Izabelle R. Farias, Luina B. Lima, Raquel C. Montenegro

Summary: This review discusses the sequence and structural differences of S proteins among SARS-CoV, MERS-CoV, and SARS-CoV-2, highlighting their importance in infection, transmission, and evolution. It also explores the mutations in the receptor-binding domain (RBD) of these coronaviruses, as well as the mutations in the S protein of new isolates of SARS-CoV-2.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Gordian Knot: Gastrointestinal lesions caused by three highly pathogenic coronaviruses from SARS-CoV and MERS-CoV to SARS-CoV-2

Xiang Meng, Qiu-yue Lou, Wen-ying Yang, Ran Chen, Wen-hua Xu, Yang Yang, Lei Zhang, Tao Xu, Hui-fen Xiang

Summary: This article summarizes the characteristics and mechanisms of gastrointestinal lesions caused by three highly pathogenic human coronavirus infections, including SARS-CoV, MERS-CoV, and SARS-CoV-2. It points out that controlling gastrointestinal lesions can not only be used as a basis for early diagnosis, but also helps to block the transmission route of the virus, thereby better controlling the spread of the epidemic.

EUROPEAN JOURNAL OF PHARMACOLOGY (2021)

添加到收藏夹

Article Biology

Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses

Rui P. Silva, Yimin Huang, Annalee W. Nguyen, Ching-Lin Hsieh, Oladimeji S. Olaluwoye, Tamer S. Kaoud, Rebecca E. Wilen, Ahlam N. Qerqez, Jun-Gyu Park, Ahmed M. Khalil, Laura R. Azouz, Kevin C. Le, Amanda L. Bohanon, Andrea M. DiVenere, Yutong Liu, Alison G. Lee, Dzifa A. Amengor, Sophie R. Shoemaker, Shawn M. Costello, Eduardo A. Padlan, Susan Marqusee, Luis Martinez-Sobrido, Kevin N. Dalby, Sheena D'Arcy, Jason S. McLellan, Jennifer A. Maynard, Leslie Goo

Summary: Understanding the protective potential of conserved epitopes in SARS-CoV-2 and other coronaviruses is crucial for addressing the current pandemic and future outbreaks. Researchers have identified a highly conserved epitope in the S2 domain of beta-coronaviruses, specifically in the hinge region. An antibody called RAY53 targets this epitope and has been found to mediate immune responses against SARS-CoV-2 spike protein. However, mutations in the hinge region and other spike protein changes may impact antibody binding and evade existing serum antibodies. This study provides valuable insights into the targeting of S2 core epitopes and the limitations of this approach.

ELIFE (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Applying high throughput and comprehensive immunoinformatics approaches to design a trivalent subunit vaccine for induction of immune response against emerging human coronaviruses SARS-CoV, MERS-CoV and SARS-CoV-2

Abolfazl Rahmani, Masoud Baee, Kiarash Saleki, Saead Moradi, Hamid Reza Nouri

Summary: The study aimed to combat major CoVs by constructing a trivalent subunit vaccine with predicted epitopes showing strong potential to stimulate T and B-cell mediated immune responses. The vaccine exhibited strong antigenicity and stability, potentially providing a new horizon for combating SARS-CoV, MERS-CoV, and SARS-CoV-2.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)

添加到收藏夹

Review Immunology

Contribution to pathogenesis of accessory proteins of deadly human coronaviruses

Jesus Hurtado-Tamayo, Ricardo Requena-Platek, Luis Enjuanes, Melissa Bello-Perez, Isabel Sola

Summary: Coronaviruses have a large genome and include essential genes as well as variable accessory genes. The functions of accessory proteins in virus-host interactions and pathogenesis are important. Analysis of accessory proteins in the scientific literature generally involves deleting or mutating the genes, but the complexities of protein interactions during virus infection are often overlooked. A critical review of the literature helps to explain discrepancies in experimental results obtained through different approaches.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2023)

添加到收藏夹

Review Virology

Evolutionary Dynamics and Epidemiology of Endemic and Emerging Coronaviruses in Humans, Domestic Animals, and Wildlife

Ariful Islam, Jinnat Ferdous, Shariful Islam, Md Abu Sayeed, Shusmita Dutta Choudhury, Otun Saha, Mohammad Mahmudul Hassan, Tahmina Shirin

Summary: Coronaviruses can infect a variety of animals and humans, causing different diseases and significant impacts on public health and the global economy. Therefore, understanding and preventing the transmission of novel coronaviruses in different animals and humans is crucial.

VIRUSES-BASEL (2021)

添加到收藏夹

Review Environmental Sciences

Coronaviruses in humans and animals: the role of bats in viral evolution

Amr El-Sayed, Mohamed Kamel

Summary: Bats serve as a natural reservoir for many viruses, including coronaviruses, and have played a significant role in the emergence of viral diseases. Since 2002, bat-borne viruses have led to fatal epidemics like SARS and MERS. The COVID-19 pandemic in 2020, caused by a coronavirus believed to have originated from bats, has been the most devastating viral outbreak to date.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Highly pathogenic coronaviruses and the kidney

Fang Wang, Xiao-Guo Suo, Cong Wang, Jia-Nan Wang, Xiao-Yan He, Fa-Cai Wang, Juan Jin, Jia-Gen Wen, Wei-Jian Ni, Bing -Xiang Shen, Xiao-Ming Meng

Summary: The outbreak of SARS-CoV-2 since the end of 2019 has posed a significant public health challenge globally. This virus not only causes pneumonia but also leads to multiple organ failure, including kidney damage, which results in increased mortality and morbidity.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹

Review Immunology

Profile of Circulatory Cytokines and Chemokines in Human Coronaviruses: A Systematic Review and Meta-Analysis

Ayat Zawawi, Abdallah Y. Naser, Hassan Alwafi, Faisal Minshawi

Summary: This study evaluated the inflammatory cytokine profile associated with MERS-CoV, SARS-CoV, and SARS-CoV-2. The results suggest that a high level of circulating IL-6 could be associated with the severity of infection of these three coronavirus strains. The findings highlight the potential use of IL-6 as a therapeutic target to improve outcomes in severe cases.

FRONTIERS IN IMMUNOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Infection of primary nasal epithelial cells differentiates among lethal and seasonal human coronaviruses

Clayton J. Otter, Alejandra Fausto, Li Hui Tan, Alisha S. Khosla, Noam A. Cohen, Susan R. Weiss

Summary: This study compares the replication and cytotoxicity of several coronaviruses in human nasal epithelial cells. The results show that different viruses have different replication abilities and cytotoxic effects, and the status of nasal epithelial cells (such as asthma inflammation) also affects the availability of viral receptors and replication.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2023)

添加到收藏夹

Article Immunology

Species identification and antifungal susceptibility testing of Aspergillus strains isolated from patients with otomycosis in northern China

Ran Jing, Wen-Hang Yang, Meng Xiao, Ying Li, Gui-Ling Zou, Cheng-Ying Wang, Xiu-Wen Li, Ying-Chun Xu, Po-Ren Hsueh

Summary: This study provides valuable insights on the species distribution and susceptibility of Aspergillus strains isolated from otomycosis patients in China. The findings highlight the prevalence of A. welwitschiae and the existence of azole-resistance, which can guide clinical medication for otomycosis.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2022)

添加到收藏夹

Article Immunology

Potentially conjugative plasmids harboring Tn6636, a multidrug-resistant and composite mobile element, in Staphylococcus aureus

Tsai-Wen Wan, Yu-Jung Liu, Yu-Ting Wang, Yu-Tzu Lin, Jia-Chuan Hsu, Jui-Chang Tsai, Hao-Chieh Chiu, Po -Ren Hsueh, Wei-Chun Hung, Lee-Jene Teng

Summary: This study provides detailed genetic characterization of Tn6636, a multidrug-resistant mobile element, in clinical isolates of Staphylococcus aureus. The prevalence of Tn6636 in methicillin-susceptible S. aureus (MSSA) is higher than that in methicillin-resistant S. aureus (MRSA). The presence of this mobile element with various sequence types suggests its broad dissemination and the potential for continued spread of resistant plasmids.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2022)

添加到收藏夹

Article Immunology

Nationwide surveillance of antimicrobial resistance in invasive isolates of Streptococcus pneumoniae in Taiwan from 2017 to 2019

Yu-Te Tsai, Yu-Lin Lee, Min-Chi Lu, Pei-Lan Shao, Po-Liang Lu, Shu-Hsing Cheng, Wen-Chien Ko, Chi-Ying Lin, Ting-Shu Wu, Muh-Yong Yen, Lih-Shinn Wang, Chang-Pan Liu, Wen-Sen Lee, Zhi-Yuan Shi, Yao-Shen Chen, Fu-Der Wang, Shu-Hui Tseng, Chao-Nan Lin, Yu-Hui Chen, Wang-Huei Sheng, Chun-Ming Lee, Hung-Jen Tang, Chun-Yu Lin, Yen-Hsu Chen, Po-Ren Hsueh

Summary: The study suggests that empirical treatment with ceftriaxone monotherapy for pneumococcal meningitis should be carefully monitored due to its high non-susceptibility rate. However, the high susceptibility rates of most isolates to other antibiotics such as penicillin, carbapenems, respiratory quinolones, vancomycin, and linezolid indicate their potential in treating pneumococcal diseases in Taiwan.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2022)

添加到收藏夹

Article Microbiology

Geographic Patterns of Carbapenem-Resistant Pseudomonas aeruginosa in the Asia-Pacific Region: Results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) Program, 2015-2019

Yu-Lin Lee, Wen-Chien Ko, Po-Ren Hsueh

Summary: This study investigated the resistance patterns and mechanisms of Pseudomonas aeruginosa in the Asia-Pacific region from 2015 to 2019. The results showed significant variations in resistance patterns and associated genes among different countries in the region.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2022)

添加到收藏夹

Letter Infectious Diseases

BioFire FilmArray respiratory panel RP2.1 for SARS-CoV-2 detection: The pitfalls

Yu-Chang Chang, Chiung-Tzu Hsiao, Wan-Li Chen, Yang-Di Su, Po-Ren Hsueh

JOURNAL OF INFECTION (2022)

添加到收藏夹

Article Microbiology

Utility of Metagenomic Next-Generation Sequencing for Etiological Diagnosis of Patients with Sepsis in Intensive Care Units

Jung-Yien Chien, Chong-Jen Yu, Po-Ren Hsueh

Summary: The performance of metagenomic next-generation sequencing (mNGS) was evaluated and compared with that of conventional culture testing in patients with sepsis. mNGS had higher detection rates than blood culture and BALF culture, especially for bacteria, viruses, and multipathogen infections. RNA-based mNGS increased the detection rate of several bacteria, fungi, and viruses. mNGS offers a sensitive diagnostic method for patients with sepsis, but clinical correlation is advised to interpret the data due to the lack of unified diagnostic criteria.

MICROBIOLOGY SPECTRUM (2022)

添加到收藏夹

Letter Infectious Diseases

Rapid emergence of ceftazidime-avibactam resistance among carbapenem-resistant Enterobacterales in a tertiary-care hospital in Taiwan

Jia-Arng Lee, Shin-Hei Du, Tai-fen Lee, Yu-Shan Huang, Chun-Hsing Liao, Yu-Tsung Huang, Po-Ren Hsueh

JOURNAL OF INFECTION (2023)

添加到收藏夹

Letter Infectious Diseases

Catheter-related bloodstream infection due to Bordetella trematum

Jia-Arng Lee, Tai-Fen Lee, Yu-Tsung Huang, Po-Ren Hsueh

JOURNAL OF INFECTION (2022)

添加到收藏夹

Letter Infectious Diseases

In vitro activity of imipenem/relebactam, meropenem/vaborbactam and comparators against Pseudomonas aeruginosa in Taiwan: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART) in 2020

Yuag-Meng Liu, Wen-Chien Ko, Mao-Wang Ho, Yu-Lin Lee, Po-Ren Hsueh

JOURNAL OF INFECTION (2023)

添加到收藏夹

Letter Infectious Diseases

Direct prediction of ceftazidime-resistant Stenotrophomonas maltophilia from routine MALDI-TOF mass spectra using machine learning

Jiaxin Yu, Hsiu-Hsien Lin, Kun-Hao Tseng, Ni Tien, Po-Ren Hsueh, Der-Yang Cho

JOURNAL OF INFECTION (2023)

添加到收藏夹

Review Virology

Multisystem inflammatory syndrome in adults: Characteristics, treatment, and outcomes

Chih-Cheng Lai, Chi-Kuei Hsu, Shun-Chung Hsueh, Muh-Yong Yen, Wen-Chien Ko, Po-Ren Hsueh

Summary: Following the emergence of multisystem inflammatory syndrome in children (MIS-C), a similar clinical scenario called multisystem inflammatory syndrome in adults (MIS-A) has been observed. Although the prevalence of MIS-A is low and likely underdiagnosed, it can be associated with high mortality. MIS-A is a multisystem disease that affects the cardiovascular, respiratory, gastrointestinal, dermatologic, hematologic, and neurologic systems. The diagnosis of MIS-A requires clinical manifestations, laboratory evidence of inflammation, and SARS-CoV-2 infection. The appropriate treatment for MIS-A is still uncertain, but anti-inflammatory agents like intravenous immunoglobulin and corticosteroids are commonly used. Further research is needed to determine the true prevalence, pathogenesis, and effective treatment for MIS-A.

JOURNAL OF MEDICAL VIROLOGY (2023)

添加到收藏夹

Review Virology

Coronavirus disease 2019 rebounds following nirmatrelvir/ritonavir treatment

Chih-Cheng Lai, Po-Ren Hsueh

Summary: Nirmatrelvir/ritonavir (NMV-r) is an effective antiviral agent for treating nonhospitalized COVID-19 patients. However, there have been rare cases of virologic and symptomatic rebound after NMV-r treatment, which is a cause for concern. This review provides comprehensive information on the frequency, mechanism, outcomes, and management of COVID-19 rebound after NMV-r. The incidence of rebound was less than 2% and most cases had mild symptoms, with favorable clinical outcomes.

JOURNAL OF MEDICAL VIROLOGY (2023)

添加到收藏夹

Letter Infectious Diseases

Emergence of meropenem and levofloxacin resistance in Burkholderia pseudomallei in Taiwan

Pin-Han Wu, Chih-Hao Chen, Wen-Hsin Hsih, Chia-Huei Chou, Chih-Yu Chi, Mao-Wang Ho, Yu-Tzu Lin, Hsiu-Hsien Lin, Kun-Hao Tseng, Po-Ren Hsueh

JOURNAL OF INFECTION (2023)

添加到收藏夹

Article Immunology

Immune responses and safety of COVID-19 vaccination in atypical hemolytic uremic syndrome patients in Taiwan

I-Ru Chen, Guei-Jane Wang, Po-Ren Hsueh, Chia-Hui Chou, Long-Bin Jeng, Hui-Ju Lin, Huang-Jiun Liao, Ping-Chin Lai, Jan-Gowth Chang, Chiu-Ching Huang

Summary: This study evaluated the immune responses and safety of COVID-19 vaccination in patients with atypical hemolytic uremic syndrome (aHUS) in Taiwan. The results showed that the vaccines effectively protected aHUS patients from severe COVID-19 complications without significant safety concerns. Transplant aHUS patients had lower immune response titers, indicating a need for additional vaccine doses.

VACCINE (2023)

添加到收藏夹

Article Microbiology

Evaluating NG-Test CARBA 5 Multiplex Immunochromatographic and Cepheid Xpert CARBA-R Assays among Carbapenem-Resistant Enterobacterales Isolates Associated with Bloodstream Infection

Yu-Tsung Huang, Yao-Wen Kuo, Nan-Yao Lee, Ni Tien, Chun-Hsing Liao, Lee-Jene Teng, Wen-Chien Ko, Po-Ren Hsueh

Summary: Detection of carbapenemase-producing Enterobacterales is important for therapeutic decisions and infection control. The Xpert CARBA-R and NG-Test CARBA 5 assays showed high sensitivity and specificity in detecting carbapenemases in carbapenem-resistant Enterobacterales isolates.

MICROBIOLOGY SPECTRUM (2022)

添加到收藏夹

暂无数据

© Peeref 2019-2024. All rights reserved.