Anti‐inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor‐bearing mice

Novel modulation on myeloid-derived suppressor cells (MDSCs) by methionine encephalin (MENK)

(2019) Jin Geng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

mTOR-mediated glycolysis contributes to the enhanced suppressive function of murine tumor-infiltrating monocytic myeloid-derived suppressor cells

(2018) Yuting Deng et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Upregulation of IL-11, an IL-6 Family Cytokine, Promotes Tumor Progression and Correlates with Poor Prognosis in Non-Small Cell Lung Cancer

(2018) Meng Zhao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Fenofibrate prevents skeletal muscle loss in mice with lung cancer

(2018) Marcus D. Goncalves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenformin Inhibits Myeloid-Derived Suppressor Cells and Enhances the Anti-Tumor Activity of PD-1 Blockade in Melanoma

(2017) Sun Hye Kim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Connecting the Metabolic and Immune Responses to Cancer

(2017) Thomas R. Flint et al.   TRENDS IN MOLECULAR MEDICINE

CD13hi Neutrophil-like myeloid-derived suppressor cells exert immune suppression through Arginase 1 expression in pancreatic ductal adenocarcinoma

(2017) Jing Zhang et al.   OncoImmunology

Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis

(2016) Selma Masri et al.   CELL

Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity

(2016) Thomas R. Flint et al.   Cell Metabolism

Methionine enkephalin, its role in immunoregulation and cancer therapy

(2016) Dingliang Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer

(2016) Lucia D’Amico et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Elevated levels of polymorphonuclear myeloid-derived suppressor cells in patients with glioblastoma highly express S100A8/9 and arginase and suppress T cell function

(2016) Paul R. Gielen et al.   NEURO-ONCOLOGY

mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors

(2016) Tingting Wu et al.   Scientific Reports

Metabolic Reprogramming of Immune Cells in Cancer Progression

(2015) Subhra K. Biswas   IMMUNITY

Versatile functions for IL-6 in metabolism and cancer

(2015) Jan Mauer et al.   TRENDS IN IMMUNOLOGY

SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells

(2015) H. Yu et al.   Cancer Immunology Research

Phenotype, development, and biological function of myeloid-derived suppressor cells

(2015) Yang Zhao et al.   OncoImmunology

IFN-γ regulates survival and function of tumor-induced CD11b+Gr-1highmyeloid derived suppressor cells by modulating the anti-apoptotic molecule Bcl2a1

(2014) José Medina-Echeverz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-155 and MicroRNA-21 Promote the Expansion of Functional Myeloid-Derived Suppressor Cells

(2014) L. Li et al.   JOURNAL OF IMMUNOLOGY

Opioid growth factor – opioid growth factor receptor axis inhibits proliferation of triple negative breast cancer

(2013) Ian S Zagon et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Targeting the opioid growth factor: Opioid growth factor receptor axis for treatment of human ovarian cancer

(2013) Ian S Zagon et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma

(2013) Tamar Kapanadze et al.   JOURNAL OF HEPATOLOGY

Opioid growth factor (OGF) for hepatoblastoma: a novel non-toxic treatment

(2012) Moshe Rogosnitzky et al.   INVESTIGATIONAL NEW DRUGS

Cyclophosphamide Promotes Chronic Inflammation–Dependent Immunosuppression and Prevents Antitumor Response in Melanoma

(2012) Alexandra Sevko et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis

(2011) Lei Zhao et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

(2011) C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

(2010) Cesar A. Corzo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cell proliferation of human ovarian cancer is regulated by the opioid growth factor-opioid growth factor receptor axis

(2009) Renee N. Donahue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis

(2009) Patricia J McLaughlin et al.   BMC CANCER

Myeloid-derived suppressor cells in mammary tumor progression in FVB Neu transgenic mice

(2009) Fuminori Abe et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Liver Is a Site for Tumor-Induced Myeloid-Derived Suppressor Cell Accumulation and Immunosuppression

(2009) Dan Ilkovitch et al.   CANCER RESEARCH

Therapeutic targeting of myeloid-derived suppressor cells

(2009) Stefano Ugel et al.   CURRENT OPINION IN PHARMACOLOGY

CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver

(2009) H. Kuniyasu et al.   GUT

Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells

(2009) C. A. Corzo et al.   JOURNAL OF IMMUNOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE