Article
Biochemistry & Molecular Biology
Fuqiang Ge, Qiaoling Yu, Jun Zhang, Yaoyao Han, Dongfa Zhu, Xi Xie
Summary: The E93 gene was identified and found to be widely distributed in adult tissues of the swimming crab. The expression levels of PtE93 mRNA in Y-organ and epidermis fluctuated during the molt cycle, suggesting its involvement in juvenile molting. Treatment with 20E induced PtE93 expression, while treatment with MF showed the opposite effect. The study also observed a negative correlation between PtE93 and ecdysteroid biosynthesis genes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biotechnology & Applied Microbiology
Huanyu Du, Runting Ge, Ling Zhang, Jiangyan Zhang, Keping Chen, Chengjun Li
Summary: In this study, we used RNA-seq and qRT-PCR analysis to identify differentially expressed transcripts in Tribolium castaneum during different developmental stages. Functional enrichment analysis revealed that genes related to DNA replication, cell cycle, and insect hormone biosynthesis were significantly enriched. The transcription of DNA replication and cell cycle genes decreased after hatching but increased after pupation. The study also showed that silencing the ecdysteroid degradation gene CYP18A1 resulted in developmental arrest at the late larval stage. Overall, this research contributes to our understanding of insect growth and development.
Article
Chemistry, Multidisciplinary
Hunter S. Sims, Pedro Andrade Horn, Ryota Isshiki, Melissa Lim, Yan Xu, Robert H. Grubbs, Mingji Dai
Summary: The concise and stereoselective total synthesis of the clinically relevant tricyclic prostaglandin D-2 metabolite methyl ester was achieved in eight steps using a variety of organic reactions. The synthesis also accumulated a significant amount of valuable material for clinical research purposes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Endocrinology & Metabolism
Yin Fu, Fengying Zhang, Chunyan Ma, Wei Wang, Zhiqiang Liu, Wei Chen, Ming Zhao, Lingbo Ma
Summary: This study evaluated the effects of multiple hormones on the ovarian development of the mud crab and identified key metabolic pathways. It was found that different hormones had varying effects on lipid metabolism and ovarian maturation.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Xilei Li, Tiantian Chen, Yang Han, Mengting Huang, Hucheng Jiang, Jiawei Huang, Minhui Tao, Ruihan Xu, Qiming Xie, Shiping Su
Summary: The study identified the Met gene in the Chinese mitten crab as a potential receptor for MF, involved in regulating vitellogenesis. The expression of EsMet and EsVg in the hepatopancreas varied significantly during different developmental stages, with a corresponding change in MF concentration.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2021)
Article
Fisheries
Yotsawan Tinikul, Ruchanok Tinikul, Attakorn Engsusophon, Prasert Sobhon
Summary: In this study, the effects of two short neuropeptide F (Mro-sNPF) mature sequences on ovarian maturation and spawning in Macrobrachium rosenbergii females were investigated. The results showed that both Mro-sNPF peptides significantly shortened the ovarian developmental period, enhanced the gonadosomatic index, oocyte diameter, and cell proliferation. Additionally, the peptides induced spawning, elevating hemolymph vitellogenin concentrations and upregulating MrEcR transcripts.
Article
Biochemistry & Molecular Biology
Xilei Li, Tiantian Chen, Ruihan Xu, Mengting Huang, Jiawei Huang, Qiming Xie, Fan Liu, Shiping Su, Keyi Ma
Summary: MF is a crucial substance in regulating physiological processes in crustaceans, and understanding its synthetic and degradation pathways is important for maintaining appropriate levels of MF. This study identified Es-CXE5 as potentially responsible for degrading MF in the hepatopancreas of Chinese mitten crab, potentially impacting ovarian development.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2021)
Article
Marine & Freshwater Biology
F. N. Lambert, H. R. Gracy, A. J. Gracy, S. H. Yoon, R. W. Scott, D. M. Rincon, C. D. Vulpe
Summary: Chronic exposure to organic UV filters can adversely affect the development and long-term health of crustaceans, such as Daphnia magna, with significant alterations in the expression of certain endocrine-related genes.
AQUATIC TOXICOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Ming Zhao, Fengying Zhang, Wei Wang, Zhiqiang Liu, Chunyan Ma, Yin Fu, Wei Chen, Lingbo Ma
Summary: The study identified the complete MF biosynthesis pathway in Scylla paramamosain and found that most genes involved in or related to MF synthesis were highly expressed in the mandibular organ, suggesting a crucial regulatory role for the methionine cycle pathway genes during MF synthesis. The phylogenetic and tissue distribution analysis also revealed a possible regulatory discrepancy in the methionine cycle between crustaceans and insects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Physiology
Takumi Kamiyama, Ryusuke Niwa
Summary: This review summarizes the crucial transcriptional regulators controlling the expression of ecdysteroid biosynthetic enzymes and their roles in insect development, using the fruit fly Drosophila melanogaster as a model organism.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Fisheries
Chang Xu, Xiaolong Yang, Zhenye Liang, Zongzheng Jiang, Hu Chen, Fenglu Han, Yongyi Jia, Erchao Li
Summary: The optimal supplementation of lipid nutrients, particularly krill oil, showed significant improvement in gonadal development and maturation in adult female aquatic animals. It increased gonadosomatic index, cholesterol deposition, and yolk granule deposition, while reducing the secretion of gonad-inhibiting hormones.
AQUACULTURE NUTRITION
(2023)
Article
Toxicology
Kenji Toyota, Tomomi Sato, Taisen Iguchi, Tsuyoshi Ohira
Summary: The freshwater zooplanktonDaphnia magna has been used in ecotoxicology studies for males offspring production. A reliable male- or female-producing system was established using Daphnia pulexWTN6 strain by changing the rearing photoperiod, revealing factors such as ionotropic glutamate receptors and protein kinase C. The study provided an experimental method for in vivo screening of both JH agonists and antagonists and suggested divergent male sex-determining processes betweenD. magnaandD. pulex.
JOURNAL OF APPLIED TOXICOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Xilei Li, Tiantian Chen, Hucheng Jiang, Jiawei Huang, Mengting Huang, Ruihan Xu, Qiming Xie, Haojie Zhu, Shiping Su
Summary: The study explored the role of Es-Kr-h1 gene in crustacean development, suggesting its involvement in ovarian maturation and the JH/MF signaling pathway in E. sinensis. The results also indicated potential conservation of these pathways in crustaceans.
ANIMAL REPRODUCTION SCIENCE
(2021)
Article
Marine & Freshwater Biology
Juan C. F. Pardo, Tania M. Costa
Summary: This study investigated the combined effects of elevated temperature and decreased pH on the embryonic development of the estuarine fiddler crab Leptuca thayeri. Results showed that higher temperature led to faster embryo development but lower survival rate, while lower pH resulted in more advanced embryonic stages. The study provides insights on the synergistic effects of warming and acidification on burrowing estuarine organisms.
ESTUARINE COASTAL AND SHELF SCIENCE
(2021)
Review
Pharmacology & Pharmacy
Zhiran Ju, Menglan Li, Junde Xu, Daniel C. Howell, Zhiyun Li, Fen-Er Chen
Summary: Cyclooxygenases play a vital role in inflammation, but currently used anti-inflammatory drugs have associated adverse effects. Researchers are searching for novel selective COX-2 inhibitors.
ACTA PHARMACEUTICA SINICA B
(2022)
Article
Endocrinology & Metabolism
B. P. Girish, Ch. Swetha, P. Sreenivasula Reddy
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2015)
Article
Multidisciplinary Sciences
B. P. Girish, Ch. Swetha, P. Sreenivasula Reddy
Article
Toxicology
Ch. Supriya, B. Akhila, K. Pratap Reddy, B. P. Girish, P. Sreenivasula Reddy
TOXICOLOGY MECHANISMS AND METHODS
(2016)
Article
Chemistry, Multidisciplinary
C. H. Swetha, B. P. Girish, P. Sreenivasula Reddy
Article
Toxicology
Ch. Supriya, B. Akhila, K. Pratap Reddy, B. P. Girish, P. Sreenivasula Reddy
TOXICOLOGY MECHANISMS AND METHODS
(2016)
Article
Biochemistry & Molecular Biology
B. P. Girish, P. Sreenivasula Reddy
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
(2018)
Article
Biochemistry & Molecular Biology
B. P. Girish, C. H. Swetha, M. Srilatha, M. Hemalatha, P. Sreenivasula Reddy
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2018)
Article
Food Science & Technology
D. Archana, Ch. Supriya, B. P. Girish, B. Kishori, P. Sreenivasula Reddy
FOOD AND CHEMICAL TOXICOLOGY
(2018)
Article
Toxicology
A. K. Sai Siva Ram, K. Pratap Reddy, B. P. Girish, Ch. Supriya, P. Sreenivasula Reddy
TOXICOLOGY RESEARCH
(2018)
Article
Oncology
Bala Prabhakar Girish, Begum Dariya, Mastan Mannarapu, Ganji Purnachandra Nagaraju, Ganji Seeta Rama Raju
Summary: Pancreatic cancer faces challenges from abnormal proliferation of stromal cells, and traditional treatments may cause excessive toxicity to normal cells. Nanotechnology can deliver drugs directly to tumor sites, enhancing treatment efficacy.
SEMINARS IN CANCER BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Saritha Marella, Peddanna Kotha, S. Abdul Nabi, B. P. Girish, Kameswara Rao Badri, Apparao Chippada
Summary: The Mcy protein has insulin-like structure and/or function, and it increases the expression of key regulators of glucose and lipid metabolism. Additionally, it enhances insulin-receptor binding and alters the number and affinity of insulin receptors on erythrocyte membranes.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Review
Nutrition & Dietetics
Begum Dariya, Bala Prabhakar Girish, Neha Merchant, Mundla Srilatha, Ganji Purnachandra Nagaraju
Summary: Resveratrol, a natural phytochemical, shows potential in inhibiting colorectal cancer progression and reducing multidrug resistance. It targets multiple cancer-promoting pathways and transcription factors, inhibiting CRC development and reducing the formation of an immunosuppressive tumor microenvironment.
Article
Agriculture, Multidisciplinary
T. N. V. K. V. Prasad, G. C. Satisha, A. R. Nirmal Kumar, M. Swethasree, B. P. Girish, P. Sudhakar, B. Ravindra Reddy, M. Saritha, N. Sabitha, B. V. Bhaskar Reddy, P. Rajasekhar, L. Prasanthi
Summary: In this study, the effects of foliar spray of nanoscale silica and osic acid on chili plants were investigated. The results showed that foliar application of particulate nanoscale silica increased the flexural rigidity and nutrient content of chili plants.
ACS AGRICULTURAL SCIENCE & TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
B. P. Girish, Ch Swetha, P. Sreenivasula Reddy
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2017)