Derivation of notochordal cells from human embryonic stem cells reveals unique regulatory networks by single cell‐transcriptomics

Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis

(2018) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells

(2018) Ruhang Tang et al.   Stem Cell Research & Therapy

Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes

(2017) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis

(2017) Nahid Akhtar et al.   NUTRITION

A Polyphenol-rich Pomegranate Fruit Extract Suppresses NF-κB and IL-6 Expression by Blocking the Activation of IKKβ and NIK in Primary Human Chondrocytes

(2017) Abdul Haseeb et al.   PHYTOTHERAPY RESEARCH

A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects by suppressing IL-1β-induced activation of AP-1 in human OA chondrocytes

(2017) Nazir M. Khan et al.   Scientific Reports

Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes

(2017) Abdul Haseeb et al.   Scientific Reports

Sucrose, But Not Glucose, Blocks IL1-β-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway

(2016) Nazir M. Khan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Regeneration of Articular Cartilage by Human ESC-Derived Mesenchymal Progenitors Treated Sequentially with BMP-2 and Wnt5a

(2016) Jason D. Gibson et al.   Stem Cells Translational Medicine

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Native nucleus pulposus tissue matrix promotes notochordal differentiation of human induced pluripotent stem cells with potential for treating intervertebral disc degeneration

(2014) Yongxing Liu et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Modulating Notochordal Differentiation of Human Induced Pluripotent Stem Cells Using Natural Nucleus Pulposus Tissue Matrix

(2014) Yongxing Liu et al.   PLoS One

Establishment of Human cell Type-Specific iPS cells with Enhanced Chondrogenic Potential

(2014) Rosa M. Guzzo et al.   Stem Cell Reviews and Reports

Differentiation of Mouse Induced Pluripotent Stem Cells (iPSCs) into Nucleus Pulposus-Like Cells In Vitro

(2013) Jun Chen et al.   PLoS One

Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system

(2013) Brian H Chon et al.   Stem Cell Research & Therapy

Bilirubin augments radiation injury and leads to increased infection and mortality in mice: Molecular mechanisms

(2012) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Why Patients Visit Their Doctors: Assessing the Most Prevalent Conditions in a Defined American Population

(2012) Jennifer L. St. Sauver et al.   MAYO CLINIC PROCEEDINGS

A Novel Mammal-Specific Three Partite Enhancer Element Regulates Node and Notochord-Specific Noto Expression

(2012) Leonie Alten et al.   PLoS One

TCF/LEFs and Wnt Signaling in the Nucleus

(2012) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

Pro-oxidants ameliorate radiation-induced apoptosis through activation of the calcium–ERK1/2–Nrf2 pathway

(2011) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Immunomodulatory and immunotoxic effects of bilirubin: molecular mechanisms

(2011) Nazir M. Khan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

Isolation and Characterization of Node/Notochord-Like Cells from Mouse Embryonic Stem Cells

(2011) Maria K. Winzi et al.   STEM CELLS AND DEVELOPMENT

Exploiting notochord cells for stem cell-based regeneration of the intervertebral disc

(2011) Matthew R. McCann et al.   Journal of Cell Communication and Signaling

Foxd3 is an essential Nodal-dependent regulator of zebrafish dorsal mesoderm development

(2010) Lisa L. Chang et al.   DEVELOPMENTAL BIOLOGY

Toward an understanding of the role of notochordal cells in the adult intervertebral disc: From discord to accord

(2010) Makarand V. Risbud et al.   DEVELOPMENTAL DYNAMICS

Debating the Value of Spine Surgery*

(2010) Edward N Hanley et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord

(2009) Kanako Ukita et al.   MECHANISMS OF DEVELOPMENT

Future perspectives of cell-based therapy for intervertebral disc disease

(2008) Daisuke Sakai   EUROPEAN SPINE JOURNAL

Marking Embryonic Stem Cells with a 2A Self-Cleaving Peptide: A NKX2-5 Emerald GFP BAC Reporter

(2008) Edward C. Hsiao et al.   PLoS One