Tubulin polyglutamylation is a general traffic-control mechanism in hippocampal neurons

Polyglutamylation of tubulin’s C-terminal tail controls pausing and motility of kinesin-3 family member KIF1A

(2019) Dominique V Lessard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biallelic variant in AGTPBP1 causes infantile lower motor neuron degeneration and cerebellar atrophy

(2019) Mert Karakaya et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Biallelic variants in AGTPBP1, involved in tubulin deglutamylation, are associated with cerebellar degeneration and motor neuropathy

(2019) Ruth Sheffer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Axonal transport and neurological disease

(2019) James N. Sleigh et al.   Nature Reviews Neurology

Axonal transport: Driving synaptic function

(2019) Pedro Guedes-Dias et al.   SCIENCE

Microtubule-Associated Proteins: Structuring the Cytoskeleton

(2019) Satish Bodakuntla et al.   TRENDS IN CELL BIOLOGY

Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons

(2018) Xiu-Tang Cheng et al.   JOURNAL OF CELL BIOLOGY

The cytoplasmic dynein transport machinery and its many cargoes

(2018) Samara L. Reck-Peterson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cytoskeleton stability is essential for the integrity of the cerebellum and its motor- and affective-related behaviors

(2018) Rodrigo Muñoz-Castañeda et al.   Scientific Reports

Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease

(2018) Amandine Virlogeux et al.   Cell Reports

Neuronal network maturation differently affects secretory vesicles and mitochondria transport in axons

(2018) Eve Moutaux et al.   Scientific Reports

Loss of tubulin deglutamylase CCP1 causes infantile‐onset neurodegeneration

(2018) Vandana Shashi et al.   EMBO JOURNAL

Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport

(2018) Maria M Magiera et al.   EMBO JOURNAL

CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice

(2018) Stephen Gilmore-Hall et al.   JOURNAL OF CELL BIOLOGY

The impact of cytoskeletal organization on the local regulation of neuronal transport

(2017) Jeffrey J. Nirschl et al.   NATURE REVIEWS NEUROSCIENCE

Neuronal cell-type classification: challenges, opportunities and the path forward

(2017) Hongkui Zeng et al.   NATURE REVIEWS NEUROSCIENCE

Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases

(2017) Scott T. Brady et al.   NEUROBIOLOGY OF DISEASE

Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

(2017) Roderick P. Tas et al.   NEURON

Mutations modifying sporadic Alzheimer's disease age of onset

(2016) Jorge I. Vélez et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Graded Control of Microtubule Severing by Tubulin Glutamylation

(2016) Max L. Valenstein et al.   CELL

Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits

(2016) Bing Zhou et al.   JOURNAL OF CELL BIOLOGY

Mechanisms and functions of lysosome positioning

(2016) Jing Pu et al.   JOURNAL OF CELL SCIENCE

The cellular mechanisms that maintain neuronal polarity

(2016) Marvin Bentley et al.   NATURE REVIEWS NEUROSCIENCE

Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B

(2016) Amy E. Ghiretti et al.   NEURON

Microtubule Organization Determines Axonal Transport Dynamics

(2016) Shaul Yogev et al.   NEURON

HDAC6 Inhibitors Rescued the Defective Axonal Mitochondrial Movement in Motor Neurons Derived from the Induced Pluripotent Stem Cells of Peripheral Neuropathy Patients with HSPB1 Mutation

(2016) Ji-Yon Kim et al.   Stem Cells International

Hierarchical Microtubule Organization Controls Axon Caliber and Transport and Determines Synaptic Structure and Stability

(2015) Raiko Stephan et al.   DEVELOPMENTAL CELL

Microtubule detyrosination guides chromosomes during mitosis

(2015) M. Barisic et al.   SCIENCE

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

(2014) Ghazaleh Ashrafi et al.   JOURNAL OF CELL BIOLOGY

The tubulin code: Molecular components, readout mechanisms, and functions

(2014) Carsten Janke   JOURNAL OF CELL BIOLOGY

The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids

(2014) Olivia Tort et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

(2014) Sandra Maday et al.   NEURON

Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport

(2013) Diana Zala et al.   CELL

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

The Dynamic Synapse

(2013) Daniel Choquet et al.   NEURON

One-Step Sequence- and Ligation-Independent Cloning as a Rapid and Versatile Cloning Method for Functional Genomics Studies

(2012) Jae-Yeon Jeong et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Regulation of Mitochondrial Transport and Inter-Microtubule Spacing by Tau Phosphorylation at the Sites Hyperphosphorylated in Alzheimer's Disease

(2012) K. Shahpasand et al.   JOURNAL OF NEUROSCIENCE

Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy

(2011) S. Lee et al.   JOURNAL OF NEUROSCIENCE

KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons

(2011) K.Y. Lo et al.   NEUROSCIENCE LETTERS

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration

(2010) Krzysztof Rogowski et al.   CELL

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

(2010) Benjamin Lacroix et al.   JOURNAL OF CELL BIOLOGY

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

(2009) Yoshiyuki Konishi et al.   NATURE NEUROSCIENCE

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Synaptic activation modifies microtubules underlying transport of postsynaptic cargo

(2009) C. Maas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced Sensitivity of Striatal Neurons to Axonal Transport Defects Induced by Mutant Huntingtin

(2008) L.-S. Her et al.   JOURNAL OF NEUROSCIENCE

The Function of Mitochondria in Presynaptic Development at the Neuromuscular Junction

(2007) Chi Wai Lee et al.   MOLECULAR BIOLOGY OF THE CELL