Article
Engineering, Chemical
Jia Du, Leilei Fan, Qinghe Wang, Fanfei Min
Summary: The research demonstrates that illite can be stripped to increase adsorption sites and regulating the generated Cr(III) hydrolysate can enhance or weaken adsorption on the illite surface, thus optimizing the regeneration performance of clay mineral materials.
Article
Chemistry, Multidisciplinary
Qing Wang, Yanzhao Xu, Jianhe Hu
Summary: This study explored the intracellular mechanism of antimicrobial peptide HJH-3 in killing Salmonella. The results showed that HJH-3 can bind bacterial DNA, inhibit its diffusion and migration, penetrate the bacterial cell membrane, and cause DNA fragmentation and release of intracellular contents. The death rate of Salmonella increased significantly after exposure to HJH-3, indicating its potential as a candidate antimicrobial agent for Salmonella pullorum infections.
Editorial Material
Medicine, Research & Experimental
Karin E. Bornfeldt
Summary: Recent research shows that omega-3 fatty acids can reduce plasma triglyceride levels through a mechanism involving N-acyl taurines, inhibiting intestinal triglyceride hydrolysis, and reducing lipid absorption, providing protection against high-fat diet-induced plasma triglyceride levels and hepatic triacylglycerol accumulation.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Veterinary Sciences
John N. Hertzer, Madeline Fujishiro, Sara D. Lawhon, Kate E. Creevy
Summary: This case report discusses the diagnosis and management of Salmonella prostatitis in a five-year-old intact male Labrador Retriever mix dog, along with comorbidities such as heartworm infestation. Recommendations to mitigate zoonotic spread were emphasized, including frequent hand washing and using an isolated area for urination and defecation.
BMC VETERINARY RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Hanis Hidayu Kasim, Laurentya Olga, Stuart Snowden, Eliza Cropp, Albert Koulman, Kathryn Beardsall
Summary: This study reveals differences in desaturase enzyme activity between preterm and term infants, especially during the first few weeks of life. It suggests that lipid metabolism in preterm infants may have implications for later metabolic health.
LIPIDS IN HEALTH AND DISEASE
(2023)
Article
Immunology
Frank E. A. Hayford, Mumin Ozturk, Robin C. Dolman, Renee Blaauw, Arista Nienaber, Du Toit Loots, Frank Brombacher, Cornelius M. Smuts, Suraj P. Parihar, Linda Malan
Summary: Experimental results of using ibuprofen and n-3 LCPUFA as adjunct therapies in tuberculosis treatment show that n-3 LCPUFAs help reduce lung bacterial load, increase alveolar space, and exhibit higher levels of lipid mediators. Ibuprofen benefits the host in the short term, but its effectiveness is not consistent throughout the entire course of tuberculosis treatment.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Haydar A. Mohammad-Salim, Huda Ahmed Basheer, Hassan H. Abdallah, Abdellah Zeroual, Lazgin Abdi Jamil
Summary: The [3+2] cycloaddition reactions of N-benzylcyclohexylnitrone with methyl-3-butenoate were studied using molecular electron density theory. The zwitterionic reactions occur through a one-step mechanism and result in the formation of four different products. Analysis using global electron density transfer revealed differences in activation enthalpy among the reaction paths. Bonding evolution theory suggests the formation of new covalent bonds in the transition states of these reactions.
NEW JOURNAL OF CHEMISTRY
(2021)
Review
Pharmacology & Pharmacy
Ram Prasad Aganja, Chandran Sivasankar, Amal Senevirathne, John Hwa Lee
Summary: Bacteria-mediated cancer therapy, particularly using Salmonella, shows promise in localizing and inhibiting tumor growth. Salmonella can deliver toxins or tumor antigens to specifically target cancer cells and stimulate the host immune system. It can also deliver prodrug converting enzymes against cancer. While the results from clinical trials have been unsatisfactory, Salmonella-mediated therapy opens up possibilities for combinatorial treatments with chemotherapy, radiotherapy, and surgery, especially for drug-resistant and advanced stage cancers.
Article
Materials Science, Multidisciplinary
H. Akther, M. Mahbubur Rahman, A. H. Bhuiyan, Humayun Kabir, Sm Amir-Al Zumahi, J. A. Syed, Rahima Nasrin
Summary: In this study, PPTMA thin films were produced through plasma polymerisation process and evaluated using various characterisation techniques. The results showed that iodine-doped PPTMA films exhibited higher conductivity compared to the as-deposited ones.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Nutrition & Dietetics
Lauren A. Roach, Mitchell K. Byrne, Steven J. Howard, Stuart J. Johnstone, Marijka Batterham, Ian M. R. Wright, Anthony D. Okely, Renate H. M. de Groot, Inge S. M. van der Wurff, Alison L. Jones, Barbara J. Meyer
Summary: The study investigated the effect of n-3 LCPUFA supplementation on self-regulation and executive functioning in typically developing preschool-aged children, showing no significant improvements in these areas. Further research is needed to target children with sub-optimal self-regulation who may benefit most from n-3 LCPUFA supplementation.
Article
Cell Biology
Shiyao Xu, Guiqiu Hu, Di Wu, Xingchi Kan, Hisashi Oishi, Satoru Takahashi, Shoupeng Fu, Juxiong Liu, Chuan Zhang
Summary: The overexpression of MafK increases susceptibility to Salmonella infection and exacerbates the disease by promoting epithelial cell apoptosis, leading to bacterial dissemination and inflammation.
Article
Chemistry, Physical
Zhaohui Guo, Chunyan Chen, Jiancheng Zhao, Xiaoya Guo, Lingyu Jia, Pengfei Liu, Christian Marcus Pedersen, Xianglin Hou, Yan Qiao, Yingxiong Wang
Summary: This study proposed a method for the conversion of N-acetyl-D-glucosamine to 3-acetamido-5-acetylfuran using boric acid and 1-allyl-3-methylimidazolium chloride catalyst. The mechanism was investigated using primary nuclear magnetic resonance technology, and the catalytic interactions were studied through chemical shift titration and mass spectroscopy.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Physics, Applied
Shuaiyan Liu, Kuibo Lan, Zhi Wang, Lixia Long, Junqing Wei, Ruibing Chen, Guoxuan Qin
Summary: Detection of bacterial contamination in food is crucial for public health and safety. In this study, we developed a highly sensitive olfactory receptor-derived peptide (ORP) sensor for detecting 3-methyl-1-butanol, a by-product of common meat-borne bacteria. The sensor, which was attached to carbon nanotubes (CNTs) using a combination of substrate modification, thioester modification, and chemical ligation, exhibited remarkable sensitivity with a detection limit three orders of magnitude lower than previous reports. The selectivity and stability of the sensor make it a promising tool for applications in food safety, medical detection, and environmental protection.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Organic
Anupam Karmakar, Po-Cheng Yu, Femil J. Shajan, Vijay K. Chatare, William A. Sabbers, Eduardo M. Sproviero, Rodrigo B. Andrade
Summary: The diastereoselective alpha-hydroxylation of N-tertbutanesulfinyl metallodienenamine and metalloenamines with Davis oxaziridine has been achieved with high yields and diastereomeric ratios. The choice of metal bases dramatically influences the diastereoselectivity and stereoselectivity of the reaction. DFT computational modeling has provided mechanistic insights, suggesting the importance of aza-enolate geometry in the facial approach. A one-pot protocol for the asymmetric synthesis of 1,2-amino alcohols has been developed.
Article
Geochemistry & Geophysics
Junfeng Pan, Taotao Du, Jiaming Gao, Fei Xie
Summary: This study analyzed a case study of the Hongqinghe coal mine in order to reveal the occurrence mechanism of rockburst in deep multipillar gob-side entry. The research discovered an essential difference between the surrounding rock load characteristics of multipillar gob-side entry and single-pillar gob-side entry. New control methods were also proposed to reduce both the foundation static load and the opportune static load that induce rockburst.
Article
Biochemistry & Molecular Biology
Junsheng Liu, Zhennan Gu, Wenwei Lu, Diangeng Hu, Xi Zhao, Hongxuan Huang, Hao Zhang, Jianxin Zhao, Wei Chen
Article
Biochemistry & Molecular Biology
Junsheng Liu, Diangeng Hu, Yingqi Chen, Hongxuan Huang, Hao Zhang, Jianxin Zhao, Zhennan Gu, Wei Chen
Article
Microbiology
Junsheng Liu, Zhennan Gu, Fanfen Song, Hao Zhang, Jianxin Zhao, Wei Chen
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Food Science & Technology
Junsheng Liu, Zhennan Gu, Hao Zhang, Jianxin Zhao, Wei Chen
LWT-FOOD SCIENCE AND TECHNOLOGY
(2019)
Article
Nutrition & Dietetics
Fanfen Song, Junsheng Liu, Wenyu Zhao, Hongxuan Huang, Diangeng Hu, Haiqin Chen, Hao Zhang, Wei Chen, Zhennan Gu
Article
Food Science & Technology
Junsheng Liu, Jun Liu, Liu Liu, Guangwen Zhang, Aimei Zhou, Xichun Peng
FOOD RESEARCH INTERNATIONAL
(2020)
Article
Agriculture, Multidisciplinary
Junsheng Liu, Jun Liu, Shan Duan, Liu Liu, Guangwen Zhang, Xichun Peng
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2020)
Article
Food Science & Technology
Yunjing Chen, Shuxiu Zheng, Guangwen Zhang, Jianming Luo, Junsheng Liu, Xichun Peng
Summary: This study investigated the macronutrients, trace elements, microbial community, and extracellular metabolites of artificially cultured Taisui, discovering that most of the metabolites are beneficial to human health. While acTS may not be a good source of macronutrients and trace elements, and the safety of some microorganisms remains unknown, it does provide probiotics and beneficial metabolites for human consumption. Further research is needed to ensure the safety of each microorganism before developing acTS into food products.
FOOD SCIENCE & NUTRITION
(2021)
Article
Food Science & Technology
Junsheng Liu, Xiangfei Li, Fanfen Song, Shumao Cui, Wenwei Lu, Jianxin Zhao, Hao Zhang, Zhennan Gu, Wei Chen
Summary: The study found that low dose xylooligosaccharide (XOS) can promote the anti-Salmonella activity of probiotic Lactiplantibacillus plantarum ZS2058 by increasing survival rate and changing gut microbiota to protect the host.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Junsheng Liu, Liu Liu, Guangwen Zhang, Xichun Peng
Summary: Both Poria cocos polysaccharides (PPs) and finasteride have therapeutic effects on chronic nonbacterial prostatitis (CNP) rats, but they work through different mechanisms, with PPs alleviating CNP symptoms by modulating the gut microbiota.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Youying Tu, Hyunuk Kang, Eunhye Kim, Jiangfan Yang, Puming He, Yuanyuan Wu, Bo Li, Xiaobo Liu, Junsheng Liu
Summary: The study found that Tieguanyin tea extracts could alter fecal metabolites in AD mice, with Tgy-C being the most effective. Metabolomics analysis showed Tgy-C's reduction effect on fecal metabolites in AD mice, which may involve pathways like protein digestion and absorption, and amino acid biosynthesis.
Article
Biochemistry & Molecular Biology
Junsheng Liu, Jun Liu, Liu Liu, Guangwen Zhang, Xichun Peng
Summary: Researchers found that dexamethasone-induced osteoporosis and APS-ameliorated osteoporosis altered the gene expression profile of the intestine, resulting in intestinal dysfunction. APS was able to restore intestinal functions by affecting 53 differentially expressed genes, contributing to the improvement of osteoporosis. This study supports the concept of a gut-bone axis and suggests new therapeutic opportunities for osteoporosis treatment through this axis.
Article
Agriculture, Multidisciplinary
Junsheng Liu, Juntong Yu, Xichun Peng
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2020)