Recent Advances in Lipopolysaccharide Recognition Systems

Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis

(2019) Xiaoli Huang et al.   Cell and Bioscience

Innate immunity to intracellular LPS

(2019) Vijay A. K. Rathinam et al.   NATURE IMMUNOLOGY

Differential effects of lipopolysaccharide on mouse sensory TRP channels

(2018) Brett Boonen et al.   CELL CALCIUM

LPS targets host guanylate‐binding proteins to the bacterial outer membrane for non‐canonical inflammasome activation

(2018) José Carlos Santos et al.   EMBO JOURNAL

A historical perspective on the role of sensory nerves in neurogenic inflammation

(2018) João Sousa-Valente et al.   Seminars in Immunopathology

A Thermodynamic Funnel Drives Bacterial Lipopolysaccharide Transfer in the TLR4 Pathway

(2018) Roland G. Huber et al.   STRUCTURE

Differential interactions of bacterial lipopolysaccharides with lipid membranes: implications for TRPA1-mediated chemosensation

(2018) Justyna B. Startek et al.   Scientific Reports

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

(2018) Meihong Deng et al.   IMMUNITY

A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death

(2018) Shigetoshi Yokoyama et al.   eLife

Reconstruction of LPS Transfer Cascade Reveals Structural Determinants within LBP, CD14, and TLR4-MD2 for Efficient LPS Recognition and Transfer

(2017) Je-Kyung Ryu et al.   IMMUNITY

The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll-Like Receptor 4 (TLR4) Signalling

(2017) Florent Cochet et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization

(2017) Carmen L. Krüger et al.   Science Signaling

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins

(2017) Ryan Finethy et al.   mBio

Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization

(2017) Carmen L. Krüger et al.   Science Signaling

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

(2016) Sivapriya Kailasan Vanaja et al.   CELL

Structure and function: Lipid A modifications in commensals and pathogens

(2016) Alex Steimle et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Complement pathway amplifies caspase-11–dependent cell death and endotoxin-induced sepsis severity

(2016) Brooke A. Napier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gustatory-mediated avoidance of bacterial lipopolysaccharides via TRPA1 activation in Drosophila

(2016) Alessia Soldano et al.   eLife

High Mobility Group Box 1 Protein Binding to Lipopolysaccharide Facilitates Transfer of Lipopolysaccharide to CD14 and Enhances Lipopolysaccharide-Mediated TNF-  Production in Human Monocytes

(2014) J. H. Youn et al.   JOURNAL OF IMMUNOLOGY

Recognition of LPS by TLR4: Potential for Anti-Inflammatory Therapies

(2014) Reindert Nijland et al.   Marine Drugs

A Cross-Disciplinary Perspective on the Innate Immune Responses to Bacterial Lipopolysaccharide

(2014) Yunhao Tan et al.   MOLECULAR CELL

Inflammatory caspases are innate immune receptors for intracellular LPS

(2014) Jianjin Shi et al.   NATURE

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

(2014) Etienne Meunier et al.   NATURE

TRPV4: physiological role and therapeutic potential in respiratory diseases

(2014) Neil M. Goldenberg et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS

(2014) D. M. Pilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins

(2014) Victor Meseguer et al.   Nature Communications

TRPV4-Mediated Calcium Influx and Ciliary Activity in Human Native Airway Epithelial Cells

(2013) Lisa Alenmyr et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

The atypical lipopolysaccharide ofFrancisella

(2013) Nihal A. Okan et al.   CARBOHYDRATE RESEARCH

The Structural Basis for Endotoxin-induced Allosteric Regulation of the Toll-like Receptor 4 (TLR4) Innate Immune Receptor

(2013) Teresa Paramo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis

(2013) Brittany D. Needham et al.   NATURE REVIEWS MICROBIOLOGY

Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila

(2013) C. L. Case et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Caspase-11 Protects Against Bacteria That Escape the Vacuole

(2013) Y. Aachoui et al.   SCIENCE

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

(2013) N. Kayagaki et al.   SCIENCE

Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens

(2012) Prajwal Gurung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Endotoxin·albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

(2011) Gregory A Esparza et al.   Innate Immunity

LPS Sensitizes TRPV1 via Activation of TLR4 in Trigeminal Sensory Neurons

(2011) A. Diogenes et al.   JOURNAL OF DENTAL RESEARCH

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

The transient receptor potential family of ion channels

(2011) Bernd Nilius et al.   GENOME BIOLOGY

Differential Induction of Innate Immune Responses by Synthetic Lipid A Derivatives

(2010) Jidnyasa Gaekwad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide From Porphyromonas gingivalis Sensitizes Capsaicin-Sensitive Nociceptors

(2010) Caio Cezar Randi Ferraz et al.   JOURNAL OF ENDODONTICS

C-Type Lectin SIGN-R1 Has a Role in Experimental Colitis and Responsiveness to Lipopolysaccharide

(2010) Sean P. Saunders et al.   JOURNAL OF IMMUNOLOGY

Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception

(2010) Kyeongjin Kang et al.   NATURE

Erratum to “Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: Chemical synthesis and functional studies”

(2010) Shoichi KUSUMOTO et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

(2010) W. Everaerts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heteromerization of TRP channel subunits: extending functional diversity

(2010) Wei Cheng et al.   Protein & Cell

TRPV1 controls acid- and heat-induced calcitonin gene-related peptide release and sensitization by bradykinin in the isolated mouse trachea

(2009) Tatjana I. Kichko et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Variation of Neisseria gonorrhoeae Lipooligosaccharide Directs Dendritic Cell–Induced T Helper Responses

(2009) Sandra J. van Vliet et al.   PLoS Pathogens

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

(2008) Natsuko Tanimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Innate signaling by the C-type lectin DC-SIGN dictates immune responses

(2008) Jeroen den Dunnen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Caspases — An update

(2008) Indrajit Chowdhury et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I

(2008) K. S. Thorneloe et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY

TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells

(2008) I. M. Lorenzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY