Article
Chemistry, Analytical
V. Ruzsanyi, H. Wiesenhofer, C. Ager, J. Herbig, G. Aumayr, M. Fischer, M. Renzler, T. Ussmueller, K. Lindner, C. A. Mayhew
Summary: Human smuggling is a significant part of transnational organized crime, posing a growing threat to national and international security. Detecting and intercepting hidden humans in containers or trucks at transportation hubs is crucial. A portable device combining ion mobility spectrometry and sensor array system can quickly detect volatile organic compounds emitted by humans, with a classification algorithm providing a simple YES or NO decision. Field measurements show that it takes 20 to 30 minutes for emitted trace compounds to reach detectable concentrations.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Oncology
Ekaterina Smirnova, Christopher Mallow, John Muschelli, Yuan Shao, Jeffrey Thiboutot, Andres Lam, Ana M. Rule, Ciprian Crainiceanu, Lonny Yarmus
Summary: The study evaluated the performance of Acetoin concentration in exhaled breath for the diagnosis of stage 1 lung cancer, with results showing an accuracy of 0.610 in the test data. In multivariate logistic models, the best performing models included Acetoin alone (AUC = 0.650).
TRANSLATIONAL LUNG CANCER RESEARCH
(2022)
Article
Plant Sciences
Shixing Zhou, Toshmatov Zokir, Yu Mei, Lijing Lei, Kai Shi, Ting Zou, Chi Zhang, Hua Shao
Summary: The study revealed that the shrub Serphidium kaschgaricum in northwestern China releases volatile organic compounds (VOCs) to inhibit the growth of surrounding plants, with eucalyptol and camphor being the dominant constituents in the oils. Less abundant compounds in the oils also significantly contribute to the phytotoxic activity observed.
Article
Engineering, Environmental
Thomas Virdis, Christophe Walgraeve, Angelos Ioannidis, Herman Van Langenhove, Joeri F. M. Denayer
Summary: Metal-Organic Frameworks (MOFs) have been extensively researched for applications like gas storage and heterogeneous catalysis, but the study of VOCs adsorption on MOFs is still behind compared to traditional adsorbent materials. This research used innovative methods to explore VOCs adsorption on MOFs at ultra-low concentrations, finding that UiO-66 exhibited higher uptake compared to ZIF-8 and both MOFs showed preference for hydrophobic molecules.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Myriam Guillevic, Aurore Guillevic, Martin K. Vollmer, Paul Schlauri, Matthias Hill, Lukas Emmenegger, Stefan Reimann
Summary: A new data analysis method was proposed for automated fragment formula annotation of unknown compounds measured by GC-EI-HRMS. Validated on a variety of halocarbons and hydrocarbons, the method reliably reconstructed fragment chemical formulae in a vast majority of cases, demonstrating its suitability for non-targeted analysis.
JOURNAL OF CHEMINFORMATICS
(2021)
Article
Biochemistry & Molecular Biology
Wojciech Fabianowski, Miroslaw Maziejuk, Monika Szyposzynska, Monika Wisnik-Sawka
Summary: The article presents a technique of differential ion mobility spectrometry (DMS) for the detection and identification of volatile organic compounds (VOCs) from various categories. It analyzes the possibility of mixture identification using only the DMS spectrometer and provides several examples. The article also discusses the analysis of different compounds, their mechanisms of fragmentation, influence on effective ion temperature, and high electric field intensity.
Review
Environmental Sciences
Zhujun Yu, Ying Li
Summary: Volatile organic compounds (VOCs) are crucial in global atmospheric chemistry, with marine VOC distribution and their role still unclear, necessitating further research.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Food Science & Technology
Lili Chang, Songyi Lin, Bowen Zou, Xiaohan Zheng, Simin Zhang, Yue Tang
Summary: This study investigated the effects of different frying conditions on the quality characteristics of fried Spanish mackerel, with findings indicating that frying at 160 degrees C with 65% moisture content resulted in the highest food quality of fish filets. The results provide a theoretical basis for improving the food quality of self-heated fish products.
Article
Chemistry, Applied
Siyang Deng, Yunhe Liu, Feng Huang, Jiqian Liu, Dong Han, Chunhui Zhang, Christophe Blecker
Summary: The study showed that white pig and black pig bacon have different volatile components during refrigerated storage, with white pig bacon having higher phenols and acids while black pig bacon containing more alcohols, ketones, and nitrogen-containing compounds. White pig bacon was more affected by storage compared to black pig bacon, and the difference in raw materials between the two types of bacon was found to be the main reason for their flavor variations.
Article
Food Science & Technology
Yanqiu Han, Chen Wang, Xiaoli Zhang, Xiao Li, Ya Gao
Summary: This study investigated the characteristic volatile compounds across the fermentation process of Dongbei Suancai (DS) using HS-GC-IMS combined with PCA, identifying 19 representative flavor substances in the samples. Differences in volatiles between naturally and inoculated-fermented DS at different fermentation stages were detected, with notable changes in flavor profile observed as fermentation progressed, particularly with the addition of Lactobacillus Plantarum as a starter culture. The combination of HS-GC-IMS and PCA proved to be an effective tool for analyzing the characteristic volatiles in DS samples, showing potential for identification and classification of DS flavor.
JOURNAL OF FOOD SCIENCE
(2022)
Review
Biotechnology & Applied Microbiology
Nils Kunze-Szikszay, Maximilian Euler, Thorsten Perl
Summary: Traditional microbiological methods for diagnosing bacterial infections have led to long turnaround times, but detecting VOCs emitted by bacteria presents a potential innovative approach for rapid diagnosis. Spectrometric methods allow for the detection and quantification of bacterial VOCs with high sensitivity.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Peng Leng, Hang-Wei Hu, Ai-Hua Cui, Hong-Jie Tang, Yun-Guo Liu
Summary: This study developed the flavor fingerprint of post-harvest peach fruits from Amygdalus persica L. Yingshuanghong (YSH) using HS-GC-IMS and identified the impact of different preservation methods on volatile organic compounds (VOCs). The results showed an increase in VOCs content in YSH with storage time, primarily esters, while aldehydes and alcohols decreased.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Medicine, General & Internal
Thanikan Sukaram, Terapap Apiparakoon, Thodsawit Tiyarattanachai, Darlene Ariyaskul, Kittipat Kulkraisri, Sanparith Marukatat, Rungsun Rerknimitr, Roongruedee Chaiteerakij
Summary: This study investigated the potential of volatile organic compounds (VOCs) as biomarkers for hepatocellular carcinoma (HCC) diagnosis and treatment monitoring. The combination of 9 VOCs showed promising sensitivity, specificity, and accuracy for HCC diagnosis. Acetone dimer had a better performance than alpha-fetoprotein (AFP) in differentiating early HCC from cirrhotic patients. Isopropyl alcohol was found to be associated with the survival of HCC patients. VOC analysis offers a feasible noninvasive approach for diagnosing and monitoring HCC.
Article
Food Science & Technology
Ruixiao Wu, Chunjie Yang, Linjie Xi, Tian Wang, Ju Zhang, Liping Kou, Wu Ding
Summary: This study investigated the impact of high pressure and temperature (HTHP) and electron-beam irradiations on the volatile compounds and sensory characteristics of cooked bacon. The results showed that higher irradiation doses significantly reduced the variety of volatile compounds and sensory features, but increased the concentration of certain compounds. Treatments with doses below 5 kGy did not affect the volatile compounds and sensory properties. High-temperature-high-pressure conditions had a significant impact on the concentrations of volatile compounds and sensory traits. Electronic nose was effective in detecting flavor differences among different sterilization methods. Fingerprinting analysis revealed significant differences between the HTHP and 9 kGy-treated groups and other treatments. The study suggested that 5 kGy might be the optimal dose for maintaining the original flavor and sensory properties of cooked bacon.
Article
Biochemical Research Methods
Xu Jia, Hanghang Zhang, Xiangfu Jiang, Yaling Lu, Wenjie Liu, Jianna Yu
Summary: This study used ambient pressure electrospray ionisation ion mobility spectrometry coupled to HPLC to detect alkaloids from different parts of Sophora alopecuroides L. extracts, revealing the distribution of major alkaloids and providing extra separation ability to resolve co-eluted peaks. The method improved signal-to-noise ratio and maintained high resolving power, demonstrating its potential for qualitative and quantitative analysis of alkaloids.
PHYTOCHEMICAL ANALYSIS
(2021)
Article
Biochemistry & Molecular Biology
Bartosz Michalczuk, Wieslawa Barszczewska, Waldemar Wysocki, Stefan Matejcik
Summary: In this study, rate coefficients and activation energies for several silicon chlorides in the gas phase were measured using the pulsed Townsend technique. A linear relation between rate coefficients and activation energies for chlorosilanes was demonstrated. The study also found a relationship between geometry changes associated with negative ion formation and the polarizability of the attaching center.
Review
Physics, Multidisciplinary
S. A. Pshenichnyuk, N. L. Asfandiarov, A. S. Vorob'ev, S. Matejcik
Summary: This paper presents the latest achievements in experimental and theoretical studies of resonance scattering of low-energy electrons from molecular targets, leading to the formation and decay of negative ions. The focus is on dissociative electron attachment spectroscopy for studying the dynamics of molecules with an excess electron. The paper aims to draw attention to these rapidly developing studies abroad that have been scarcely presented in domestic literature.
Article
Biochemical Research Methods
Ladislav Moravsky, Bartosz Michalczuk, Arian Fateh Borkhari, Peter Papp, Alexey A. Sysoev, Stefan Matejcik
Summary: The study utilized CD-APCI in combination with IMS and IMS-oaTOF-MS for the fast and sensitive detection of phthalates, showing the potential to differentiate some isomeric compounds.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2021)
Article
Chemistry, Physical
Juraj Orszagh, Anita Ribar, Marian Danko, Dennis Bodewits, Stefan Matejcik, Wieslawa Barszczewska
Summary: This study investigated the excitation of nitromethane through electron impact and recorded the emission spectrum at different electron energies. New dissociative excitation channels were observed, and the emission spectrum had significantly higher resolution compared to previous studies.
Article
Biochemical Research Methods
Vahideh Ilbeigi, Younes Valadbeigi, Ladislav Moravsky, Stefan Matejcik
Summary: In this study, ion mobility spectrometry (IMS) equipped with a corona discharge (CD) ion source was used to measure three auxin plant hormones. The effects of ion polarity and dopants on separation performance were investigated.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Ladislav Moravsky, Arian Fateh Borkhari, Alexey Yu Adamov, Alexey A. Sysoev, Peter Papp, Stefan Matejcik
Summary: This study investigated the atmospheric pressure chemical ionization of selected chlorinated hydrocarbons using ion mobility spectrometry and mass spectrometry techniques. The experiments revealed the formation of Cl- ions and [O2H center dot center dot Cl](-) ions for all substances, with the latter being absent in perchlorinated substances. Quantum-chemical calculations supported the experimental observations.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Physics, Fluids & Plasmas
Jan Durian, Peter Hartmann, Stefan Matejcik, Andrew R. Gibson, Zoltan Donko
Summary: A low-pressure capacitively coupled RF helium discharge with a structured electrode was investigated experimentally and via kinetic simulations. The experiment used phase resolved optical emission spectroscopy to provide information on the excitation dynamics of high energy electrons with high spatial and nanosecond temporal resolution. The numerical studies were based on a newly developed particle-in-cell/Monte Carlo collisions code and studied the fluxes of He+ ions and vacuum ultraviolet photons incident on different surfaces.
PLASMA SOURCES SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Physical
Ashin Shaji, Karol Vegso, Michaela Sojkova, Martin Hulman, Peter Nadazdy, Yuriy Halahovets, Lenka Pribusova Slusna, Tatiana Vojtekova, Jana Hrda, Matej Jergel, Eva Majkova, Joerg Wiesmann, Peter Siffalovic
Summary: This study provides a comprehensive in-situ investigation of the chemical reactions during the growth of MoS2 thin film using chemical vapor deposition (CVD). The results demonstrate the phase transformations of MoO3 to MoO2 and MoO2 to MoS2, highlighting the importance of understanding these chemical reactions for optimizing the properties of the final 2D TMD films.
APPLIED SURFACE SCIENCE
(2022)
Article
Agriculture, Multidisciplinary
Vahideh Ilbeigi, Younes Valadbeigi, L'udmila Slovakova, Stefan Matejcik
Summary: In this study, a method combining solid phase microextraction (SPME) with multicapillary column (MCC) and ion mobility spectrometry (IMS) was developed to detect MeSA in tomato leaves. The two-dimensional separation provided by MCC and IMS enabled efficient detection of MeSA, and the negative polarity operation reduced interferences.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Instruments & Instrumentation
Karol Vegso, Ashin Shaji, Michaela Sojkova, Lenka Pribusova Slusna, Tatiana Vojtekova, Jana Hrda, Yuriy Halahovets, Martin Hulman, Matej Jergel, Eva Majkova, Joerg Wiesmann, Peter Siffalovic
Summary: This article introduces an in situ observation method for the growth of few-layer MoS2, utilizing a microfocus X-ray source and a 2D X-ray detector to easily distinguish the orientation of the MoS2 layers, and monitoring the growth in real time by tracking the width of the diffraction peak.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2022)
Article
Nanoscience & Nanotechnology
Michal Koci, Tibor Izsak, Gabriel Vanko, Michaela Sojkova, Jana Hrda, Ondrej Szabo, Miroslav Husak, Karol Vegso, Marian Varga, Alexander Kromka
Summary: This study synthesizes MoS2 and H-NCD thin films using appropriate physical/chemical deposition methods, and analyzes their performance in gas sensing properties. The results show that the MoS2/H-NCD heterostructure-based gas sensor exhibits improved sensitivity to oxidizing NO2 and reducing NH3 gases. Different gas interaction model pathways were developed to describe the current flow mechanism through the sensing area.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Physical
Michaela Sojkova, Igor Pis, Jana Hrda, Tatiana Vojtekova, Lenka Pribusova Slusna, Karol Vegso, Peter Siffalovic, Peter Nadazdy, Edmund Dobrocka, Milos Krbal, Paul J. Fons, Frans Munnik, Elena Magnano, Martin Hulman, Federica Bondino
Summary: It has been found that lithium can promote the epitaxial growth and horizontal alignment of MoS2, and lithiation can cause a vertical-to-horizontal reorientation in vertically aligned MoS2 films. The horizontally aligned Li-doped MoS2 exhibits good long-term stability and preserved chemical composition.
CHEMISTRY OF MATERIALS
(2023)
Article
Biochemical Research Methods
Vahideh Ilbeigi, Younes Valadbeigi, Ladislav Moravsky, Stefan Matejcik
Summary: Formic acid (FA) is a powerful dopant in atmospheric pressure chemical ionization (APCI) for ion mobility spectrometry (IMS) and mass spectrometry (MS). The dopant produces HCOO-&FA reactant ions and improves detection sensitivity, suppression of fragmentation, and changes in ion mobilities for analytes with suitable molecular structures and gas acidity. The ionization mechanism depends on the gas-phase acidity of the compounds.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Arian Fateh Borkhari, Ladislav Moravsky, Stefan Matejcik
Summary: An Atmospheric Pressure Field Effect (APFE) ionization source has been developed for positive and negative polarities in drift tube ion mobility spectrometry. The formation of negative and positive ions in synthetic air was compared with the Atmospheric Pressure Corona Discharge (APCD) ionization source. The APFE ionization source showed reliable generation of reactant ions in both polarities, making it a promising chemical ionization source at atmospheric pressure.
ANALYTICAL METHODS
(2022)
Article
Physics, Atomic, Molecular & Chemical
Daniel D. Vallejo, Joseph L. Corstvet, Facundo M. Fernandez
Summary: Electrospray ionization (ESI) is a popular method for generating ions in mass spectrometry (MS). The use of triboelectric nanogenerators as power sources for ESI shows promise in improving the analytical capabilities. This review highlights the fundamentals of ESI driven by DC power supplies, the contrasting qualities to triboelectric nanogenerator power supplies, and its applications in forensics, metabolomics, and protein structure analysis.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2024)
Article
Physics, Atomic, Molecular & Chemical
Florian Kluibenschedl, Anna Ploner, Christina Meisenbichler, Robert Konrat, Thomas Mueller
Summary: Mass spectrometry imaging (MSI) is a powerful analytical technique for localizing chemicals on surfaces. A new interactive approach, called interactive mass spectrometry imaging (IMSI), has been developed using a pen-like ionization interface connected to a mass spectrometer. This approach allows for real-time tracking of the pen's motion on a surface to obtain chemical data. The IMSI method was successfully tested on inkjet-printed letters and mouse brain tissue samples.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2024)
Article
Physics, Atomic, Molecular & Chemical
Shubhangee S. Gaikwad, Saurabh D. Kalkate, Amruta A. Bankar, Amol S. Bansode
Summary: A stable high-performance thin layer chromatographic technique was developed and validated for estimating the content of Paracetamol and Prochlorperazine. The method was validated according to the International Conference on Harmonization requirements. The study also investigated the degradation products of the drugs.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2024)
Article
Physics, Atomic, Molecular & Chemical
Ioan Marginean
Summary: In this study, a coherent classification of electrospray axial regimes is provided based on non-linear fluid dynamics. This classification includes periodic, transient/chaotic, and stationary regimes, and emphasizes the importance of spray current measurements and electrospray characteristic curves in diagnosing the operation and transitions between these regimes. The effect of the electrospray operating regime on the mass spectrometer signal is also summarized.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2024)
Article
Physics, Atomic, Molecular & Chemical
Le Thao Anh Nguyen, Chris J. Bowen, Laura Burchill, Spencer J. Williams, Richard A. J. O'Hair
Summary: D-Cysteinolic acid (D-CA) is an important metabolite in the biosulfur cycle, while a structural isomer, (R)-3-amino-2-hydroxypropanesulfonate ((R)-AHPS), is less common. Through mass spectrometry and density-functional theory, this study reveals the fragmentation reactions of these two isomers and methods to distinguish them.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2024)
Article
Physics, Atomic, Molecular & Chemical
Frank J. Wensink, Deepak Pradeep, P. B. Armentrout, Joost M. Bakker
Summary: Methane and cyclopropane were reacted with Ru+ ions, and the resulting products were identified and characterized using mass spectrometry, IR action spectroscopy, and density functional theory calculations.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
(2024)
