It is rocket science - why dietary nitrate is hard to ‘beet’!Part II:further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway

Effect of dietary nitrate supplementation on metabolic rate during rest and exercise in human: A systematic review and a meta-analysis

(2016) Mehdi Pawlak-Chaouch et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study

(2015) Shanti Velmurugan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Sodium Nitrite Blocks the Activity of Aminoglycosides against Pseudomonas aeruginosa Biofilms

(2015) Anna C. Zemke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interactions between cocoa flavanols and inorganic nitrate: Additive effects on endothelial function at achievable dietary amounts

(2015) Ana Rodriguez-Mateos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of dietary nitrate supplementation on the oxygen cost of exercise and walking performance in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled crossover trial

(2015) Anthony I. Shepherd et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sodium Nitrite Improves Exercise Hemodynamics and Ventricular Performance in Heart Failure With Preserved Ejection Fraction

(2015) Barry A. Borlaug et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Carcinogenicity of consumption of red and processed meat

(2015) Véronique Bouvard et al.   LANCET ONCOLOGY

Dietary nitrate supplementation in COPD: An acute, double-blind, randomized, placebo-controlled, crossover trial☆

(2015) Conor P. Kerley et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Acute whole body UVA irradiation combined with nitrate ingestion enhances time trial performance in trained cyclists

(2015) David J. Muggeridge et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

The effect of dietary nitrate supplementation on the oxygen cost of cycling, walking performance and resting blood pressure in individuals with chronic obstructive pulmonary disease: A double blind placebo controlled, randomised control trial

(2015) Anthony I. Shepherd et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Dietary nitrate supplementation improves exercise performance and decreases blood pressure in COPD patients

(2015) Michael J. Berry et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

A double blind randomized placebo control crossover trial on the effect of dietary nitrate supplementation on exercise tolerance in stable moderate chronic obstructive pulmonary disease

(2015) Paul Leong et al.   BMC Pulmonary Medicine

Acute Dietary Nitrate Supplementation and Exercise Performance in COPD: A Double-Blind, Placebo-Controlled, Randomised Controlled Pilot Study

(2015) Katrina J. Curtis et al.   PLoS One

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects

(2014) Peter J. Rix et al.   CLINICAL PHARMACOKINETICS

Nitrite modulates bacterial antibiotic susceptibility and biofilm formation in association with airway epithelial cells

(2014) Anna C. Zemke et al.   FREE RADICAL BIOLOGY AND MEDICINE

UVA Irradiation of Human Skin Vasodilates Arterial Vasculature and Lowers Blood Pressure Independently of Nitric Oxide Synthase

(2014) Donald Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase

(2014) R. L. Charles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes

(2013) Mark Gilchrist et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex

(2013) Shanti Velmurugan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Safety and pharmacokinetics of sodium nitrite in patients with subarachnoid hemorrhage: a Phase IIA study

(2013) Edward H. Oldfield et al.   JOURNAL OF NEUROSURGERY

Sodium nitrite in patients with peripheral artery disease and diabetes mellitus: Safety, walking distance and endothelial function

(2013) Emile R Mohler et al.   VASCULAR MEDICINE

Co-treatment with conjugated linoleic acid and nitrite protects against myocardial infarction

(2013) Natia Qipshidze-Kelm et al.   Redox Biology

Cytotoxic Effect of the Red Beetroot (Beta vulgaris L.) Extract Compared to Doxorubicin (Adriamycin) in the Human Prostate (PC-3) and Breast (MCF-7) Cancer Cell Lines

(2012) Govind J. Kapadia et al.   Anti-Cancer Agents in Medicinal Chemistry

Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway

(2012) Satnam Lidder et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Dietary Nitrate Ameliorates Pulmonary Hypertension

(2012) Reshma S. Baliga et al.   CIRCULATION

Ingested nitrate and nitrite and stomach cancer risk: An updated review

(2012) Nathan S. Bryan et al.   FOOD AND CHEMICAL TOXICOLOGY

Dietary nitrate improves muscle but not cerebral oxygenation status during exercise in hypoxia

(2012) Evi Masschelein et al.   JOURNAL OF APPLIED PHYSIOLOGY

Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans

(2011) Filip J. Larsen et al.   Cell Metabolism

Flavonoid-rich apples and nitrate-rich spinach augment nitric oxide status and improve endothelial function in healthy men and women: a randomized controlled trial

(2011) Catherine P. Bondonno et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease

(2011) Aarti A. Kenjale et al.   JOURNAL OF APPLIED PHYSIOLOGY

Dietary nitrate reduces muscle metabolic perturbation and improves exercise tolerance in hypoxia

(2011) Anni Vanhatalo et al.   JOURNAL OF PHYSIOLOGY-LONDON

All-natural nitrite and nitrate containing dietary supplement promotes nitric oxide production and reduces triglycerides in humans

(2011) Janet Zand et al.   NUTRITION RESEARCH

Red and Processed Meat and Colorectal Cancer Incidence: Meta-Analysis of Prospective Studies

(2011) Doris S. M. Chan et al.   PLoS One

Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise

(2010) Anni Vanhatalo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Nitro–Fatty Acids Reduce Atherosclerosis in Apolipoprotein E–Deficient Mice

(2010) Tanja K. Rudolph et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nitrate and Nitrite Content of Human, Formula, Bovine, and Soy Milks: Implications for Dietary Nitrite and Nitrate Recommendations

(2010) Norman G. Hord et al.   Breastfeeding Medicine

Inorganic Nitrate Supplementation Lowers Blood Pressure in Humans

(2010) Vikas Kapil et al.   HYPERTENSION

Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans

(2010) Stephen J. Bailey et al.   JOURNAL OF APPLIED PHYSIOLOGY

Drinking Water with Red Beetroot Food Color Antagonizes Esophageal Carcinogenesis in N-Nitrosomethylbenzylamine-Treated Rats

(2010) John F. Lechner et al.   JOURNAL OF MEDICINAL FOOD

Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion

(2009) Volker Rudolph et al.   CARDIOVASCULAR RESEARCH

Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase–Dependent Nitric Oxide Generation

(2009) Brian S. Zuckerbraun et al.   CIRCULATION

Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash

(2009) Joel Petersson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitrated oleic acid up-regulates PPARγ and attenuates experimental inflammatory bowel disease

(2009) Sara Borniquel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans

(2009) Stephen J. Bailey et al.   JOURNAL OF APPLIED PHYSIOLOGY

Nitrate and nitrite in biology, nutrition and therapeutics

(2009) Jon O Lundberg et al.   Nature Chemical Biology

Dietary nitrate in Japanese traditional foods lowers diastolic blood pressure in healthy volunteers

(2009) Tanja Sobko et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation

(2009) Bárbara S. Rocha et al.   TOXICOLOGY

Mitochondrial nitroalkene formation and mild uncoupling in ischaemic preconditioning: implications for cardioprotection

(2008) Sergiy M. Nadtochiy et al.   CARDIOVASCULAR RESEARCH

The potent vasodilator ethyl nitrite is formed upon reaction of nitrite and ethanol under gastric conditions

(2008) Bruno Gago et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acute Blood Pressure Lowering, Vasoprotective, and Antiplatelet Properties of Dietary Nitrate via Bioconversion to Nitrite

(2008) Andrew J. Webb et al.   HYPERTENSION

Nitric Oxide Production from Nitrite Occurs Primarily in Tissues Not in the Blood

(2008) Haitao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzyme-Independent NO Stores in Human Skin: Quantification and Influence of UV Radiation

(2008) Megan Mowbray et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular recognition of nitrated fatty acids by PPARγ

(2008) Yong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY