CD200 maintains the region‐specific phenotype of microglia in the midbrain and its role in Parkinson's disease

Microglial immune checkpoint mechanisms

(2018) Aleksandra Deczkowska et al.   NATURE NEUROSCIENCE

Role of the CD200-CD200R Axis During Homeostasis and Neuroinflammation

(2018) Gemma Manich et al.   NEUROSCIENCE

Location, Location, Location: Microglia Are Where They Live

(2017) Margaret M. McCarthy   NEURON

Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia

(2017) Lindsay M. De Biase et al.   NEURON

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

Electroacupuncture Produces the Sustained Motor Improvement in 6-Hydroxydopamine-Lesioned Mice

(2016) Yan Yu et al.   PLoS One

α-Synuclein-Based Animal Models of Parkinson's Disease: Challenges and Opportunities in a New Era

(2016) Naomi P. Visanji et al.   TRENDS IN NEUROSCIENCES

EP2-PKA signaling is suppressed by triptolide in lipopolysaccharide-induced microglia activation

(2015) Ting Zhang et al.   Journal of Neuroinflammation

Correction: Zhang et al., An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2015)   JOURNAL OF NEUROSCIENCE

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Brain Innate Immunity in the Regulation of Neuroinflammation: Therapeutic Strategies by Modulating CD200-CD200R Interaction Involve the Cannabinoid System

(2014) Miriam Hernangomez et al.   CURRENT PHARMACEUTICAL DESIGN

Microglial phagocytosis of live neurons

(2014) Guy C. Brown et al.   NATURE REVIEWS NEUROSCIENCE

Classical activation of microglia in CD200-deficient mice is a consequence of blood brain barrier permeability and infiltration of peripheral cells

(2013) Stephanie Denieffe et al.   BRAIN BEHAVIOR AND IMMUNITY

AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model

(2013) Xinmiao Ren et al.   EXPERIMENTAL NEUROLOGY

NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration

(2013) Liya Qin et al.   GLIA

Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells

(2013) Tamara C. Hornik et al.   JOURNAL OF NEUROCHEMISTRY

rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration

(2013) Marusela Oliveras-Salvá et al.   Molecular Neurodegeneration

Factors regulating microglia activation

(2013) Katrin Kierdorf et al.   Frontiers in Cellular Neuroscience

Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia

(2012) Anthony Lyons et al.   Journal of Neuroinflammation

Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system

(2012) Susan M. Sunkin et al.   NUCLEIC ACIDS RESEARCH

Long Term Potentiation Is Impaired in Membrane Glycoprotein CD200-deficient Mice

(2011) Derek A. Costello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Microglial Phagocytosis Is Sufficient To Prevent Inflammatory Neuronal Death

(2011) J. J. Neher et al.   JOURNAL OF IMMUNOLOGY

CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease

(2011) Shi Zhang et al.   Journal of Neuroinflammation

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Downstream of Tyrosine Kinase 1 and 2 Play Opposing Roles in CD200 Receptor Signaling

(2010) R. Mihrshahi et al.   JOURNAL OF IMMUNOLOGY

Distribution of the Immune Inhibitory Molecules CD200 and CD200R in the Normal Central Nervous System and Multiple Sclerosis Lesions Suggests Neuron-Glia and Glia-Glia Interactions

(2009) Nathalie Koning et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Triptolide inhibits COX-2 expression and PGE2release by suppressing the activity of NF-κB and JNK in LPS-treated microglia

(2008) Yuntao Gong et al.   JOURNAL OF NEUROCHEMISTRY