AMP‐activated protein kinase (AMPK) regulates astrocyte oxidative metabolism by balancing TCA cycle dynamics

Integrative Characterization of the R6/2 Mouse Model of Huntington’s Disease Reveals Dysfunctional Astrocyte Metabolism

(2018) Niels H. Skotte et al.   Cell Reports

Neuroprotective Role of Trans-Resveratrol in a Murine Model of Familial Alzheimer's Disease

(2018) David Porquet et al.   JOURNAL OF ALZHEIMERS DISEASE

Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation

(2017) Michaela C Hohnholt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Metformin Prevents Dopaminergic Neuron Death in MPTP/P-Induced Mouse Model of Parkinson’s Disease via Autophagy and Mitochondrial ROS Clearance

(2016) Ming Lu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

(2016) J. A. Bayliss et al.   JOURNAL OF NEUROSCIENCE

Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases

(2016) Mary C. McKenna et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Alterations in Cerebral Cortical Glucose and Glutamine Metabolism Precedes Amyloid Plaques in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease

(2016) Jens V. Andersen et al.   NEUROCHEMICAL RESEARCH

Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-13C]Glucose and [1,2-13C]Acetate as Substrates

(2016) Laura F. McNair et al.   NEUROCHEMICAL RESEARCH

Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology

(2016) Vladimir Parpura et al.   NEUROCHEMICAL RESEARCH

Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model

(2015) Dolena R. Ledee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Adenosine Monophosphate–activated Protein Kinase Regulates Interleukin-1β Expression and Glial Glutamate Transporter Function in Rodents with Neuropathic Pain

(2015) Dylan W. Maixner et al.   ANESTHESIOLOGY

Dysfunctional TCA-Cycle Metabolism in Glutamate Dehydrogenase Deficient Astrocytes

(2015) Jakob D. Nissen et al.   GLIA

Conditional Deletion of the Glutamate Transporter GLT-1 Reveals That Astrocytic GLT-1 Protects against Fatal Epilepsy While Neuronal GLT-1 Contributes Significantly to Glutamate Uptake into Synaptosomes

(2015) G. T. Petr et al.   JOURNAL OF NEUROSCIENCE

AMPK Activation Affects Glutamate Metabolism in Astrocytes

(2015) Caroline M. Voss et al.   NEUROCHEMICAL RESEARCH

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution

(2015) Melis Karaca et al.   Cell Reports

Glutamate synthesis has to be matched by its degradation - where do all the carbons go?

(2014) Ursula Sonnewald   JOURNAL OF NEUROCHEMISTRY

Single-Cell Imaging of Bioenergetic Responses to Neuronal Excitotoxicity and Oxygen and Glucose Deprivation

(2014) N. M. C. Connolly et al.   JOURNAL OF NEUROSCIENCE

Effects of pharmacological inhibition of AMP-activated protein kinase on GLUT3 expression and the development of ischemic tolerance in astrocytes

(2014) Sadahiro Iwabuchi et al.   NEUROSCIENCE RESEARCH

Development of Mice with Brain-Specific Deletion of Floxed Glud1 (Glutamate Dehydrogenase 1) Using Cre Recombinase Driven by the Nestin Promoter

(2013) Melis Karaca et al.   NEUROCHEMICAL RESEARCH

Glutamate Pays Its Own Way in Astrocytes

(2013) Mary C. McKenna   Frontiers in Endocrinology

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission

(2012) Francesca Frigerio et al.   JOURNAL OF NEUROCHEMISTRY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate

(2012) Dorte M. Skytt et al.   NEUROCHEMISTRY INTERNATIONAL

Astrocytic energy metabolism and glutamate formation — relevance for 13C-NMR spectroscopy and importance of cytosolic/mitochondrial trafficking

(2011) Leif Hertz   MAGNETIC RESONANCE IMAGING

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

Inducible astrocytic glucose transporter-3 contributes to the enhanced storage of intracellular glycogen during reperfusion after ischemia

(2011) Sadahiro Iwabuchi et al.   NEUROCHEMISTRY INTERNATIONAL

Down-regulation of Na+-coupled glutamate transporter EAAT3 and EAAT4 by AMP-activated protein kinase

(2010) Mentor Sopjani et al.   JOURNAL OF NEUROCHEMISTRY

AMPK in the brain: its roles in energy balance and neuroprotection

(2009) Gabriele V. Ronnett et al.   JOURNAL OF NEUROCHEMISTRY

Regulation of Glucose Transporter 3 Surface Expression by the AMP-Activated Protein Kinase Mediates Tolerance to Glutamate Excitation in Neurons

(2009) P. Weisova et al.   JOURNAL OF NEUROSCIENCE

Deletion of Glutamate Dehydrogenase in ß-Cells Abolishes Part of the Insulin Secretory Response Not Required for Glucose Homeostasis

(2008) Stefania Carobbio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)

(2008) D.N. Furness et al.   NEUROSCIENCE