Review
Nutrition & Dietetics
Sangeetha Shyam, Ke Xin Lee, Angeline Shu Wei Tan, Tien An Khoo, Shivani Harikrishnan, Shehzeen Alnoor Lalani, Amutha Ramadas
Summary: Personalized nutrition is an approach that tailors nutrition advice based on individuals' genetic information. Despite interest among scholars, the impact of this approach on lifestyle habits and health has not been adequately explored. A systematic review of randomized trials suggests that there is limited evidence supporting the consistent benefits of personalized nutrition in improving dietary, behavioral, or health outcomes. Future trials should focus on improving methodological quality and expanding the generalizability of the results.
Article
Genetics & Heredity
Sara Mahdavi, David J. A. Jenkins, Ahmed El-Sohemy
Summary: This study found that the 9p21 risk genotypes have an impact on insulin sensitivity and there is an interaction between dietary patterns and genes. Following a prudent dietary pattern may protect against the effects of 9p21 risk genotypes on insulin sensitivity.
FRONTIERS IN GENETICS
(2022)
Review
Food Science & Technology
Fabio Caradonna, Ilenia Cruciata, Claudio Luparello
Summary: The intake of alcoholic beverages may have negative effects on genetic and epigenetic regulation, leading to different risks of cancer in populations based on genotypes. This review summarizes selected studies on the impact of low-dose alcohol consumption on tumorigenic pathways, including the relationship between dietary compounds and alcohol, the effects of other components in alcoholic drinks on oncogenes and oncosuppressors, and the role of alcohol within specific dietary regimens.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Nutrition & Dietetics
Anto Cordelia T. A. Dhanapal, Ramatu Wuni, Eduard F. F. Ventura, Teh Kuan Chiet, Eddy S. G. Cheah, Annaletchumy Loganathan, Phoon Lee Quen, Mahenderan Appukutty, Mohd F. M. Noh, Ian Givens, Karani Santhanakrishnan Vimaleswaran
Summary: This study aims to address malnutrition in Malaysia and proposes a conceptual framework for implementing precision nutrition strategies. The framework includes research in the fields of genetics, genomics, transcriptomics, and more, as well as training and resource development for stakeholders.
Article
Health Care Sciences & Services
Sapna Batheja, Emma M. Schopp, Samantha Pappas, Siri Ravuri, Susan Persky
Summary: This study aims to characterize the landscape of precision nutrition content on Twitter, focusing on nutrigenetics and nutrigenomics. Tweet authors, content types, and the presence of misinformation were examined.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Genetics & Heredity
Phoebe Yam, Jody Albright, Melissa VerHague, Erik R. Gertz, Fernando Pardo-Manuel de Villena, Brian J. Bennett
Summary: This study analyzed the effects of different macronutrient diets on body composition and obesity-related traits in a genetically diverse mouse population, showing significant variation in phenotypic responses among different genetic strains. The findings underscore the importance of considering genetic diversity when making dietary recommendations for weight management.
FRONTIERS IN GENETICS
(2021)
Article
Food Science & Technology
Anna Janczuk-Grabowska, Tomasz Czernecki, Aneta Brodziak
Summary: With the availability of molecular tools, population studies now consider gen-diet interactions, allowing for more uniform research groups and reduced group size while maintaining research precision. This approach can be used to select personalized ingredients and foods for dietary interventions. In terms of treating overweight and obesity, it is crucial to select bioactive ingredients that suit specific consumer groups.
Review
Agriculture, Dairy & Animal Science
Mehmet Kizilaslan, Yunus Arzik, Mehmet Ulas Cinar, Yusuf Konca
Summary: The use of genomic information in ruminant production systems can address concerns related to food security and sustainability. Nutritional genomics focuses on the interactions between nutrients and genomes, affecting gene expression patterns and genetic variations. The emerging field of ruminant nutrigenomics aims to modify ruminant nutrition based on individual genetic backgrounds, impacting productivity, quality, efficiency, disease resistance, fertility, and greenhouse gas emissions. Challenges and future directions in ruminant nutrigenomics are important areas of focus.
ANNALS OF ANIMAL SCIENCE
(2022)
Review
Genetics & Heredity
Omar Ramos-Lopez
Summary: Currently, metabolic-associated fatty liver disease (MAFLD) is a leading cause of chronic liver disease globally and is anticipated to become a common indication for liver transplantation. MAFLD is closely associated with obesity and involves multiple mechanisms. The onset and progression of MAFLD vary among individuals due to intrinsic and extrinsic factors. Structural variants in the human genome, epigenetic phenomena, gut microbiota dysbiosis, and metabolomics/lipidomic fingerprints may contribute to differences in MAFLD outcomes through interactions with nutritional features. This knowledge enhances our understanding of the molecular and physiological processes underlying MAFLD pathogenesis and heterogeneity and aids in the identification of biomarkers for disease progression and therapeutic targets for tailored nutritional strategies.
Review
Environmental Sciences
Shambhavi Srivastava, Ankit Kumar Dubey, Reecha Madaan, Rajni Bala, Yugam Gupta, Bahadur Singh Dhiman, Suresh Kumar
Summary: This article discusses the characteristics of cancer and the development of tumors, as well as the relationship between nutrition and genes. Nutrients can influence gene expression and cancer risk. Altering dietary habits can potentially reduce individual cancer risk.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Review
Nutrition & Dietetics
Amira Kohil, Spyridon Chouliaras, Shaikha Alabduljabbar, Arun Prasath Lakshmanan, Salma Hayder Ahmed, Johnny Awwad, Annalisa Terranegra
Summary: Female infertility is a significant public health concern and global challenge. The impact of dietary factors on female reproductive health and assisted reproductive technologies is substantial.
FRONTIERS IN NUTRITION
(2022)
Review
Andrology
Shelley M. Vanderhout, Matineh Rastegar Panah, Bibiana Garcia-Bailo, Patricia Grace-Farfaglia, Konrad Samsel, Judith Dockray, Keith Jarvi, Ahmed El-Sohemy
Summary: Infertility affects around 50 million couples globally, with 40-50% of cases having a male factor. Nutritional status has a significant impact on reproductive health, and genetic variation may influence fertility through nutrient metabolism.
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2021)
Review
Nutrition & Dietetics
Lynnette Ferguson, Matthew Barnett
Summary: Nutrigenomics New Zealand (NuNZ) was a collaborative research programme established by three organizations with the aim of studying the application of nutrigenomics in New Zealand and exploring its potential benefits in the plant food and agricultural sectors. The programme divided nutrigenomics into personalized nutrition and nutrigenomics, utilizing various science laboratories for comprehensive analysis to understand the impact of food products and diets on health.
Article
Medicine, Research & Experimental
Sandra Caramujo-Balseiro, Carlos Faro, Lina Carvalho
Summary: This study discusses the link between dietary habits, genes, and colorectal cancer occurrence, proposing four fundamental metabolic pathways and analyzing related gene polymorphisms. It also highlights the association between diet and genes, as well as the importance in CRC prevention or treatment.
MEDICAL HYPOTHESES
(2021)
Review
Biochemistry & Molecular Biology
Marica Franzago, Elisa Alessandrelli, Stefania Notarangelo, Liborio Stuppia, Ester Vitacolonna
Summary: The human circadian system, influenced by lifestyle and environmental factors, can be disrupted, leading to adverse effects on health. There is a complex relationship between metabolism and the circadian system, with genetic variants in clock genes playing a role. The circadian rhythm, gut microbiome, and epigenome are interconnected, and diet can modulate this complex link. Understanding these interactions can have implications for personalized nutrition and chronic disease prevention.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Lauren A. Fowler, Audrey D. Powers, Michael B. Williams, James L. Davis, Robert J. Barry, Louis R. D'Abramo, Stephen A. Watts
Summary: The study aimed to evaluate the interactions of different sources of saturated fat with sex and total dietary lipid intake on weight gain and body composition in adult zebrafish. The findings suggest that the effects of saturated fat intake on body weight gain are dependent on the intake of total dietary lipid. It is hypothesized that the impacts of saturated fat intake on energy allocation and obesity-related phenotypes are influenced by both sex and the intake of other dietary lipid components.