Article
Acoustics
T. Ikegawa, K. -s. Kim, M. Kawataki, Y. Ichikawa, S. Ono, S. Yanagi, H. Ueda
Summary: This study aimed to investigate the criteria, based on fetal TR waveforms in late gestation, to predict biventricular circulation (BV) after birth in cases of tricuspid valve dysplasia (TVD) or Ebstein's anomaly diagnosed during the fetal period. The study included 35 consecutive cases diagnosed with TVD or Ebstein's anomaly, and the data on the maximum velocity and change in pressure over time of tricuspid regurgitation (TR) jet (dP/dt) were collected. The results showed that dP/dt >= 350 mmHg/s and TR maximum velocity >= 2.9 m/s were identified as criteria for predicting the outcome in cases with a TR maximum velocity of 2.4-3.3 m/s. The performance of dP/dt >= 350 mmHg/s in predicting BV after birth was higher compared to that of TR maximum velocity >= 2.9 m/s.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shiqin Yu, Kai Yang, Xiuyu Chen, Minjie Lu, Kankan Zhao, Shujuan Yang, Jialin Song, Keshan Ji, Shihua Zhao
Summary: This study evaluated the cardiac remodeling in Ebstein's anomaly patients after surgery using cardiac magnetic resonance (CMR). The results showed that the volumes of the right ventricle and right atrium decreased significantly immediately after surgery and at follow-up, but the global longitudinal strain and right atrial reservoir strain were impaired. However, indexed left ventricular end-diastolic volume, stroke volume, and global longitudinal strain increased from preoperative to follow-up. Preoperative factors such as severity index, right ventricle and right atrium volumes, left ventricular ejection fraction, and right atrial reservoir strain were associated with RV volume normalization.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Yozo Teramachi, Lisa K. Hornberger, Lisa Howley, Mary E. van der Velde, Luke G. Eckersley
Summary: The study revealed that neonates with EA/TVD had reduced cardiac output, impaired left ventricular strain, and increased circumferential dyssynchrony. Decreased cardiac output, increased circumferential dyssynchrony, and absence of pulmonary valve flow were associated with higher mortality risk in these patients.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2022)
Article
Medicine, General & Internal
Masashi Yoshida, Hisakatsu Ito, Mitsuaki Yamazaki
Summary: Postoperative stenosis or regurgitation of the tricuspid valve is a common complication after repair surgery of Ebstein's anomaly and affects the prognosis. This article reports a case of a 17-year-old female undergoing cone reconstruction procedure for Ebstein's anomaly with intraoperative echocardiography. Intraoperative echocardiography helps evaluate the form and function of the tricuspid valve.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Paola Veronese, Alvise Guariento, Claudia Cattapan, Marny Fedrigo, Maria Teresa Gervasi, Annalisa Angelini, Arianna Riva, Vladimiro Vida
Summary: This study investigated the diagnostic performance of fetal intelligent navigation echocardiography (FINE) in identifying atrioventricular septal defects (AVSD) in prenatal cases. By using intelligent navigation technology, 100% of AVSD diagnoses were detected in the ultrasound examinations.
Article
Obstetrics & Gynecology
Jennifer E. Powel, Elena Kraus, Chetana Reddy, Kia Lannaman
Summary: This case report discusses a successful treatment of a severe fetal Ebstein's anomaly with hydrops using modest doses of nonsteroidal anti-inflammatory drug (NSAID) therapy, resulting in reversal of hydrops and avoidance of postnatal cardiac surgical intervention.
FETAL DIAGNOSIS AND THERAPY
(2022)
Review
Medicine, General & Internal
Pawel Sadlecki, Malgorzata Walentowicz-Sadlecka
Summary: Congenital malformations refer to defects in the formation of organs or body parts that can be identified during intrauterine life or at birth. Advances in prenatal detection have made it possible to identify many of these disorders early through routine fetal ultrasound. This systematic review aims to organize current knowledge on the mode of delivery in pregnancies with fetal anomalies. After analyzing 546 studies, 18 articles on delivery mode and neonatal outcomes were chosen. Spontaneous vaginal delivery is generally recommended for most pregnancies with fetal anomalies, while cesarean delivery may be indicated for certain anomalies that carry risks such as dystocia, bleeding, or rupture of protective sac. Early fetal anatomy ultrasound is crucial in providing parents with all available options, including pregnancy termination, if an anomaly is detected.
Article
Radiology, Nuclear Medicine & Medical Imaging
Irene Ferrari, Nerejda Shehu, Nicole Nagdyman, Stefan Martinoff, Peter Ewert, Heiko Stern, Christian Meierhofer
Summary: This study found that during submaximal exercise, patients with mild to moderate Ebstein's anomaly improved their cardiovascular system's total efficiency by increasing cardiac index. This was achieved by an increase in heart rate and by the recruitment of volume, as shown by an increased left ventricular end-diastolic volume and stroke volume, with simultaneous decrease in tricuspid regurgitation.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Review
Medicine, General & Internal
Kasemsri Srisupundit, Suchaya Luewan, Theera Tongsong
Summary: Fetal heart failure is a condition where the fetal heart is unable to deliver sufficient blood flow to organs, leading to various complications. Fetal echocardiography is crucial in diagnosing FHF and its underlying causes.
Article
Obstetrics & Gynecology
Karolina Rydzewska, Oskar Sylwestrzak, Michal Krekora, Maciej Slodki, Maria Respondek-Liberska
Summary: Echocardiographic examination plays a crucial role in perinatal care. Fetal Ebstein's anomaly occurred in healthy young women and was not related to fetus gender or maternal health condition.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Pediatrics
Taehong Kim, Hoon Ko, Joung-Hee Byun, Hyoung Doo Lee, Hyungtae Kim, Kwangho Choi, Joo-Young Na
Summary: Uhl's anomaly is a rare malformation characterized by the absence of right ventricular myocardium, causing right heart failure and other complications. Diagnosis is often made during fetal life.
Article
Cardiac & Cardiovascular Systems
Pin Shen, Qin Xie, Runwei Ma, Yunxing Dong, Qiang Wang, Yi Sun
Summary: This article reports a rare case of tricuspid valve malformations in twins. Through detailed analysis of the case, the necessity of individualized diagnosis and treatment, long-term follow-up observation, and the significance of choosing the appropriate timing for surgery are proposed.
JOURNAL OF CARDIOTHORACIC SURGERY
(2022)
Article
Genetics & Heredity
Ke Liu, Ming Zhu, Su-Zhen Dong
Summary: In this retrospective study, cases of fetal ectopia cordis were reported and the utility of fetal cardiovascular magnetic resonance imaging (MRI) for diagnosing this rare anomaly was evaluated. The results showed that fetal MRI combined with prenatal echocardiography can improve the accuracy of prenatal diagnosis of fetal ectopia cordis.
PRENATAL DIAGNOSIS
(2022)
Review
Pediatrics
Heather Y. Sun
Summary: Prenatal diagnosis of congenital heart defects through fetal echocardiography is crucial for early identification and protection of fetal health, allowing for timely treatment after birth to reduce complications. Therefore, prenatal screening, delivery guidance, multidisciplinary collaboration, and other measures are all vital for improving the quality of life for fetuses.
TRANSLATIONAL PEDIATRICS
(2021)
Article
Medicine, General & Internal
Mircea-Octavian Poenaru, Bashar Haj Hamoud, Romina-Marina Sima, Ionut-Didel Valcea, Radu Chicea, Liana Ples
Summary: Persistent left superior vena cava (PLSVC) is a rare congenital heart anomaly with a low incidence in the general population. Prenatal identification of PLSVC is important for a comprehensive fetal examination. Our study found a low association between PLSVC and cardiac and extracardiac anomalies. Standard ultrasound sections are insufficient to exclude cardiac anomalies when PLSVC is found.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Patricia Barbero, Laura Muguerza, Ignacio Herraiz, Antonio Garcia Burguillo, Rafael San Juan, Laura Forcen, Inmaculada Mejia, Emma Batllori, Maria Dolores Montanez, Paloma Vallejo, Olga Villar, Diana Garcia Alcazar, Alberto Galindo
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Acoustics
M. Perez-Cruz, O. Gomez, M. Gibert, N. Masoller, E. Marimon, D. Lip-Sosa, M. Bennasar, E. Bonet-Carne, M. D. Gomez-Roig, J. M. Martinez-Crespo, E. Gratacos, E. Eixarch
Summary: The study aimed to evaluate corpus callosum size in fetuses with isolated major congenital heart defects using neurosonography. Findings revealed that fetuses with major CHD had a smaller corpus callosum compared to controls, particularly in the subgroup with expected poorer brain oxygen supply. This suggests sonographic corpus callosum size could serve as a clinically feasible marker of abnormal white matter development in congenital heart defects.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Article
Obstetrics & Gynecology
Cecilia Villalain, Alberto Galindo, Daniele Di Mascio, Danilo Buca, Jose Morales-Rossello, Gabriela Loscalzo, Filomena Giulia Sileo, Alessandra Finarelli, Emma Bertucci, Fabio Facchinetti, Giuseppe Rizzo, Roberto Brunelli, Antonella Giancotti, Ludovico Muzii, Giuseppe Maria Maruotti, Luigi Carbone, Alice D'Amico, Sara Tinari, Roberta Morelli, Chiara Cerra, Luigi Nappi, Pantaleo Greco, Marco Liberati, Francesco D'Antonio, Ignacio Herraiz
Summary: The cerebroplacental (CPR) and umbilicocerebral (UCR) ratios were found to be poor predictors of adverse perinatal outcomes (APO) in both appropriate for gestational age (AGA) fetuses and those affected by late fetal growth restriction (FGR), regardless of fetal weight.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Jose Morales-Rosello, Alberto Galindo, Elisa Scarinci, Ignacio Herraiz, Silvia Buongiorno, Gabriela Loscalzo, Paula Isabel Gomez Arriaga, Antonio Jose Canada Martinez, Paolo Rosati, Antonio Lanzone, Alfredo Perales Marin
Summary: By measuring the cerebroplacental ratio (CPR) and estimated fetal weight (EFW), adverse perinatal outcome (APO) can be predicted before 34 weeks of gestation.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Beatriz Fernandez-Rodriguez, Ana Roche Gomez, Blanca Sofia Jimenez Moreno, Concepcion de Alba, Alberto Galindo, Cecilia Villalain, Carmen Pallas, Ignacio Herraiz
Summary: Smoking during pregnancy is associated with fetal growth restriction, low birthweight, and higher umbilical artery Doppler resistances, especially in late gestation.
JOURNAL OF PERINATAL MEDICINE
(2022)
Article
Biochemical Research Methods
Rosana Navajas, Antonio Ramos-Fernandez, Ignacio Herraiz, Alberto Galindo, Jose Luis Bartha, Fernando Corrales, Alberto Paradela
Summary: This study identified and validated differential exosomal proteins in liquid biopsy of pregnant women, opening up new possibilities for early detection of pre-eclampsia. In addition, the functional impact of the proteome composition of purified pre-eclamptic exosomes in target cells provides new information to better understand changes in embryo-maternal interactions and the pathogenesis of this diseas.
CLINICAL PROTEOMICS
(2022)
Editorial Material
Endocrinology & Metabolism
Ricardo Saviron-Cornudella, Ignacio Herraiz
GYNECOLOGICAL ENDOCRINOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Cecilia Villalain, Ignacio Herraiz, Paula Dominguez-Del Olmo, Pablo Angulo, Jose Luis Ayala, Alberto Galindo
Summary: This study aims to develop prediction models using machine-learning tools for the need for delivery within 7 days of diagnosis and the risk of developing HELLP syndrome or abruptio placentae in women with early onset preeclampsia. The study concludes that using maternal characteristics and routine markers at the time of diagnosis provides valuable predictive information for assessing hospitalization and timing of antenatal corticosteroid administration.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Obstetrics & Gynecology
Cecilia Villalain, Enery Gomez-Montes, Eva Felipe, David Escribano, Enrique Garcia-Torres, Miguel Angel Granados, Ignacio Herraiz, Alberto Galindo
Summary: A retrospective cohort study found that CAT can be accurately diagnosed by experts, but it still has a high perinatal mortality rate. The association with other anomalies is the most important prognostic factor.
FETAL DIAGNOSIS AND THERAPY
(2023)
Article
Acoustics
J. Rodriguez-Calvo, C. Villalain, P. I. Gomez-Arriaga, M. S. Quezada, I. Herraiz, A. Galindo
Summary: The study aimed to analyze the ability to predict perinatal survival and severe neonatal morbidity in cases of early-onset fetal growth restriction (eoFGR) using maternal variables, ultrasound parameters, and angiogenic markers at the time of diagnosis. The results showed that a model combining estimated fetal weight and maternal serum PlGF accurately predicts perinatal survival in eoFGR cases diagnosed before 28 weeks of gestation.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Review
Obstetrics & Gynecology
Paula I. Gomez-Arriaga, David Escribano, Enery Gomez-Montes, Cecilia Villalain, Alberto Mendoza, Alberto Galindo
Summary: This study evaluated isolated coronary artery fistula (CAF), and found that most cases developed symptoms during the fetal period and required perinatal treatment. Prenatal diagnosis of CAF can effectively predict the subsequent development of the disease.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Paula I. Gomez-Arriaga, Noemi Nunez, Berta Zamora, Cecilia Villalain, Beatriz Risco, Constanza Liebana, Ignacio Herraiz, Alberto Galindo
Summary: This study investigated the intrauterine evolution, associated anomalies, and neurodevelopmental outcome of fetuses with isolated mild ventriculomegaly. The results showed that 53% of the children had abnormal neurodevelopmental test scores at 2-6 years of age, but only 30% of them were diagnosed with neurological disorders.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2023)
Review
Acoustics
C. Villalain, A. J. Moon-Grady, U. Herberg, J. Strainic, J. L. Cohen, A. Shah, D. S. Levi, E. Gomez-Montes, I. Herraiz, A. Galindo
Summary: This study evaluated the accuracy of published models for predicting postnatal circulation in cases of pulmonary atresia/critical stenosis with intact ventricular septum (PA/CS-IVS). The results showed that multiparametric models performed well in predicting biventricular repair, but had low sensitivity in predicting univentricular circulation.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Enery Gomez-Montes, Enrique Salcedo Lobato, Alberto Galindo Izquierdo, Diana Garcia Alcazar, Cecilia Villalain Gonzalez, Maria Teresa Moral-Pumarega, Gerardo Bustos Lozano, Carmen Luna-Paredes
Summary: Introduction: The development of CFTR modulators has greatly improved the management of cystic fibrosis by enhancing the function of the faulty CFTR protein. Only two cases of pregnant women taking CFTR modulators therapy with CF fetuses have been reported, suggesting its potential in resolving prenatal complications. We report a case of a healthy pregnant patient who underwent CFTR modulator therapy and successfully prevented bowel obstruction in the fetus.
FETAL DIAGNOSIS AND THERAPY
(2023)
