Mucosal inflammation downregulates PHD1 expression promoting a barrier‐protective HIF‐1α response in ulcerative colitis patients

Hypoxia and inflammatory bowel disease

(2017) Eoin P. Cummins et al.   MICROBES AND INFECTION

Intestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD

(2017) Sophie Van Welden et al.   Nature Reviews Gastroenterology & Hepatology

Betulinic acid alleviates dextran sulfate sodium-induced colitis and visceral pain in mice

(2017) Jaspreet Kalra et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

ChIPBase v2.0: decoding transcriptional regulatory networks of non-coding RNAs and protein-coding genes from ChIP-seq data

(2016) Ke-Ren Zhou et al.   NUCLEIC ACIDS RESEARCH

Role of hypoxia-inducible factor-1α in pathogenesis and disease evaluation of ulcerative colitis

(2016) CHUNMEI XU et al.   Experimental and Therapeutic Medicine

Development and validation of the Nancy histological index for UC

(2015) Aude Marchal-Bressenot et al.   GUT

Activation of HIF-1α does not increase intestinal tumorigenesis

(2014) Xiang Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

(2014) Eric L. Campbell et al.   IMMUNITY

Hypoxia-inducible factor 2  regulates key neutrophil functions in humans, mice, and zebrafish

(2013) A. A. R. Thompson et al.   BLOOD

Targeting the HIF pathway in inflammation and immunity

(2013) Carsten C Scholz et al.   CURRENT OPINION IN PHARMACOLOGY

Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice

(2013) Xiang Xue et al.   GASTROENTEROLOGY

Hypoxia-Inducible Factor-2  Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis

(2012) X. Xue et al.   CANCER RESEARCH

HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitis

(2012) Masaaki Higashiyama et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Protocol: Chromatin immunoprecipitation (ChIP) methodology to investigate histone modifications in two model diatom species

(2012) Xin Lin et al.   Plant Methods

Hypoxia and Metabolic Factors That Influence Inflammatory Bowel Disease Pathogenesis

(2011) Louise E. Glover et al.   GASTROENTEROLOGY

Loss of Prolyl Hydroxylase-1 Protects Against Colitis Through Reduced Epithelial Cell Apoptosis and Increased Barrier Function

(2010) Murtaza M. Tambuwala et al.   GASTROENTEROLOGY

A CTCF-independent role for cohesin in tissue-specific transcription

(2010) D. Schmidt et al.   GENOME RESEARCH

Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

(2010) Hongxia Z. Imtiyaz et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis

(2008) C L Noble et al.   GUT

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

(2007) Eoin P. Cummins et al.   GASTROENTEROLOGY