Intraocular VEGF deprivation induces degeneration and fibrogenic response in retina

Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation

(2018) Xueting Luo et al.   Disease Models & Mechanisms

Fewer Functional Deficits and Reduced Cell Death after Ranibizumab Treatment in a Retinal Ischemia Model

(2018) Marina Palmhof et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Overview of Systematic Reviews and Meta-analyses on Systemic Adverse Events Associated With Intravitreal Anti–Vascular Endothelial Growth Factor Medication Use

(2018) Marie Thulliez et al.   JAMA Ophthalmology

Pharmacological inhibition of CCR2/5 signaling prevents and reverses alcohol-induced liver damage, steatosis and inflammation in mice

(2018) Aditya Ambade et al.   HEPATOLOGY

New approach for understanding genome variations in KEGG

(2018) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Intrinsic renal cells induce lymphocytosis of Th22 cells from IgA nephropathy patients through B7–CTLA-4 and CCL-CCR pathways

(2017) Lu Gan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Incidence and Growth of Geographic Atrophy during 5 Years of Comparison of Age-Related Macular Degeneration Treatments Trials

(2017) Juan E. Grunwald et al.   OPHTHALMOLOGY

Protective effects on the retina after ranibizumab treatment in an ischemia model

(2017) Stephanie C. Joachim et al.   PLoS One

The relationship between anti-vascular endothelial growth factor and fibrosis in proliferative retinopathy: clinical and laboratory evidence

(2016) Qi Zhang et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Distal retinal ganglion cell axon transport loss and activation of p38 MAPK stress pathway following VEGF-A antagonism

(2016) R Foxton et al.   Cell Death & Disease

Phase 2a Randomized Clinical Trial: Safety and Post Hoc Analysis of Subretinal rAAV.sFLT-1 for Wet Age-related Macular Degeneration

(2016) Ian J. Constable et al.   EBioMedicine

Induction With Intravitreal Bevacizumab Every Two Weeks in the Management of Neovascular Age-Related Macular Degeneration

(2015) Anita Barikian et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Parainflammation, chronic inflammation, and age-related macular degeneration

(2015) M. Chen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial

(2015) Elizabeth P Rakoczy et al.   LANCET

Improvement in Vision-Related Function with Intravitreal Aflibercept

(2015) Mitsuko Yuzawa et al.   OPHTHALMOLOGY

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet–Biedl syndrome

(2015) Poppy Datta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Feedback Induction of a Photoreceptor-specific Isoform of Retinoid-related Orphan Nuclear Receptor β by the Rod Transcription Factor NRL

(2014) Yulong Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Müller glial cell reprogramming and retina regeneration

(2014) Daniel Goldman   NATURE REVIEWS NEUROSCIENCE

Safety and Efficacy of Conbercept in Neovascular Age-Related Macular Degeneration

(2014) Xiaoxin Li et al.   OPHTHALMOLOGY

Electrophysiological toxicity testing of VEGF Trap-Eye in an isolated perfused vertebrate retina organ culture model

(2013) Kai Januschowski et al.   ACTA OPHTHALMOLOGICA

VEGF-A Is Necessary and Sufficient for Retinal Neuroprotection in Models of Experimental Glaucoma

(2013) Richard H. Foxton et al.   AMERICAN JOURNAL OF PATHOLOGY

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

(2013) Tamara Tchkonia et al.   JOURNAL OF CLINICAL INVESTIGATION

Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON

(2013) Soraya Rofagha et al.   OPHTHALMOLOGY

Risk of Scar in the Comparison of Age-related Macular Degeneration Treatments Trials

(2013) Ebenezer Daniel et al.   OPHTHALMOLOGY

Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1

(2013) Ling Luo et al.   eLife

Effect of Intravitreous Anti–Vascular Endothelial Growth Factor Therapy on Choroidal Thickness in Neovascular Age-Related Macular Degeneration Using Spectral-Domain Optical Coherence Tomography

(2013) Lauren Branchini et al.   JAMA Ophthalmology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Effects of bevacizumab on neuronal viability of retinal ganglion cells in rats

(2012) Maria Rosaria Romano et al.   BRAIN RESEARCH

Retinal Function and Morphology in Rabbit After Intravitreal Injection of VEGF Inhibitors

(2012) Anna Cardiakidis Myers et al.   CURRENT EYE RESEARCH

Targeted deletion of Vegfa in adult mice induces vision loss

(2012) Toshihide Kurihara et al.   JOURNAL OF CLINICAL INVESTIGATION

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Ranibizumab versus Bevacizumab to Treat Neovascular Age-related Macular Degeneration

(2012) Usha Chakravarthy et al.   OPHTHALMOLOGY

Cone arrestin confers cone vision of high temporal resolution in zebrafish larvae

(2011) Sabine L. Renninger et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Preclinical safety evaluation of subretinal AAV2.sFlt-1 in non-human primates

(2011) C-M Lai et al.   GENE THERAPY

Characteristics of Patients Losing Vision after 2 Years of Monthly Dosing in the Phase III Ranibizumab Clinical Trials

(2010) Philip J. Rosenfeld et al.   OPHTHALMOLOGY

The orphan nuclear hormone receptor ERR  controls rod photoreceptor survival

(2010) A. Onishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central Retinal Sensitivity After Intravitreal Injection of Bevacizumab for Myopic Choroidal Neovascularization

(2009) Yuko Yodoi et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Inhibition of Choroidal Neovascularization via Brief Subretinal Exposure to a Newly Developed Lentiviral Vector Pseudotyped with Sendai Viral Envelope Proteins

(2009) Yusuke Murakami et al.   HUMAN GENE THERAPY

CCR3 is a target for age-related macular degeneration diagnosis and therapy

(2009) Atsunobu Takeda et al.   NATURE

Retinoid-related orphan nuclear receptor ROR  is an early-acting factor in rod photoreceptor development

(2009) L. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris

(2009) M. Saint-Geniez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular signaling and factors involved in Müller cell gliosis: Neuroprotective and detrimental effects

(2009) Andreas Bringmann et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Hepatoprotective Effect of Infliximab, an Anti-TNF-α Agent, on Carbon Tetrachloride-Induced Hepatic Fibrosis

(2008) Ibrahim Halil Bahcecioglu et al.   INFLAMMATION

Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase

(2008) Laia Tolosa et al.   JOURNAL OF NEUROCHEMISTRY

The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy

(2008) Esther J. Kuiper et al.   PLoS One

Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Müller Cells and Photoreceptors

(2008) Magali Saint-Geniez et al.   PLoS One