期刊
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
卷 46, 期 -, 页码 S109-S121出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/ICL.0000000000000688
关键词
Allergic conjunctival diseases; Biomarkers; Pathophysiology
资金
- National Eye Institute [U10EY022881, U10EY022879]
- Office of Dietary Supplements, National Institutes of Health
Allergic conjunctival diseases (ACDs) are a group of ocular allergies that include allergic conjunctivitis, atopic keratoconjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis. Although a large body of information exists on the pathophysiology of ACDs, this has not yet lead to the development of clear recommendations and guidelines for the diagnosis of ACDs or development of conclusive and objective diagnostic tools. Identification of objectively measurable biomarkers that represent the molecular and cellular mechanisms associated with ACDs will be an important step toward achieving these aims. This is a comprehensive review of biological markers that have the potential to become biomarker(s) for ACDs and aid in the classification, diagnosis, and development of new therapeutic strategies for these group of allergic conditions.
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