A review of the pharmacokinetics of M3 muscarinic receptor antagonists used for the treatment of asthma

Inhaled Therapy in Respiratory Disease: The Complex Interplay of Pulmonary Kinetic Processes

(2018) Jens Markus Borghardt et al.   Canadian Respiratory Journal

Pharmacokinetics of tiotropium in asthmatic children aged 6-11 years support its safety profile

(2018) Ashish Sharma et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

The mode of action of anticholinergics in asthma

(2018) Reinoud Gosens et al.   EUROPEAN RESPIRATORY JOURNAL

Pharmacokinetic considerations concerning the use of bronchodilators in the treatment of chronic obstructive pulmonary disease

(2018) Maria Gabriella Matera et al.   Expert Opinion on Drug Metabolism & Toxicology

Pharmacokinetics of tiotropium administered by Respimat® in asthma patients: Analysis of pooled data from Phase II and III clinical trials

(2017) Ashish Sharma et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Role of muscarinic antagonists in asthma therapy

(2017) Mario Cazzola et al.   Expert Review of Respiratory Medicine

Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers

(2016) Jaime Algorta et al.   CLINICAL DRUG INVESTIGATION

Population Pharmacokinetics Modeling of Inhaled Umeclidinium for Adult Patients with Asthma

(2016) Shuying Yang et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Pharmacodynamics and Pharmacokinetics Following Once-Daily and Twice-Daily Dosing of Tiotropium Respimat®in Asthma Using Standardized Sample-Contamination Avoidance

(2016) Kai-Michael Beeh et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Tiotropium improves lung function, exacerbation rate, and asthma control, independent of baseline characteristics including age, degree of airway obstruction, and allergic status

(2016) Huib A.M. Kerstjens et al.   RESPIRATORY MEDICINE

New techniques for studying airway drug pharmacokinetics for asthma therapeutics

(2016) Staffan Edsbäcker   Expert Review of Clinical Pharmacology

Pharmacokinetics of Glycopyrronium Following Repeated Once-Daily Inhalation in Healthy Chinese Subjects

(2015) Romain Sechaud et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

A randomized, three-period crossover study of umeclidinium as monotherapy in adult patients with asthma

(2015) Laurie A. Lee et al.   RESPIRATORY MEDICINE

Once-daily tiotropium Respimat® 5 μg is an efficacious 24-h bronchodilator in adults with symptomatic asthma

(2015) Wolfgang Timmer et al.   RESPIRATORY MEDICINE

Pharmacokinetics and Tolerability of Inhaled Umeclidinium and Vilanterol Alone and in Combination in Healthy Chinese Subjects: A Randomized, Open-Label, Crossover Trial

(2015) Chaoying Hu et al.   PLoS One

Tiotropium may improve asthma symptoms and lung function in asthmatic patients with irreversible airway obstruction: the real-life data

(2014) Oznur Abadoglu et al.   Clinical Respiratory Journal

Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modelling approach

(2013) Christian Bartels et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Inhaled Doses of Umeclidinium in Healthy Subjects: Two Randomized Studies

(2013) Anthony Cahn et al.   CLINICAL DRUG INVESTIGATION

A new perspective on muscarinic receptor antagonism in obstructive airways diseases

(2013) Herman Meurs et al.   CURRENT OPINION IN PHARMACOLOGY

Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease

(2013) J.M. Hohlfeld et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Tiotropium in Asthma Poorly Controlled with Standard Combination Therapy

(2012) Huib A.M. Kerstjens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Long-acting muscarinic receptor antagonists for the treatment of respiratory disease

(2012) Mario Cazzola et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS