A Dysregulated DNA Methylation Landscape Linked to Gene Expression in MLL-Rearranged AML

Ranking genomic features using an information-theoretic measure of epigenetic discordance

(2019) Garrett Jenkinson et al.   BMC BIOINFORMATICS

A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium

(2018) Weili Sun et al.   BLOOD

An information-theoretic approach to the modeling and analysis of whole-genome bisulfite sequencing data

(2018) Garrett Jenkinson et al.   BMC BIOINFORMATICS

Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements

(2018) C. Roolf et al.   Journal of Hematology & Oncology

The MLL recombinome of acute leukemias in 2017

(2017) C Meyer et al.   LEUKEMIA

Potential energy landscapes identify the information-theoretic nature of the epigenome

(2017) Garrett Jenkinson et al.   NATURE GENETICS

Chromatin-state discovery and genome annotation with ChromHMM

(2017) Jason Ernst et al.   Nature Protocols

A DNA methylation map of human cancer at single base-pair resolution

(2017) E Vidal et al.   ONCOGENE

Mixed-Lineage Leukemia Fusions and Chromatin in Leukemia

(2017) Andrei V. Krivtsov et al.   Cold Spring Harbor Perspectives in Medicine

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

(2016) Eric R. Lechman et al.   CANCER CELL

Intratumoral Heterogeneity of the Epigenome

(2016) Tali Mazor et al.   CANCER CELL

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

(2016) M Ryan Corces et al.   NATURE GENETICS

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia

(2016) Sheng Li et al.   NATURE MEDICINE

TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes

(2016) John S. Welch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic Classification and Prognosis in Acute Myeloid Leukemia

(2016) Elli Papaemmanuil et al.   NEW ENGLAND JOURNAL OF MEDICINE

The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias

(2015) Vincent-Philippe Lavallée et al.   NATURE GENETICS

Epigenomic evolution in diffuse large B-cell lymphomas

(2015) Heng Pan et al.   Nature Communications

EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations

(2014) Vincent-Philippe Lavallée et al.   BLOOD

Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia

(2014) Dan A. Landau et al.   CANCER CELL

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

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STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Regulated Noise in the Epigenetic Landscape of Development and Disease

(2012) Elisabet Pujadas et al.   CELL

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

(2011) Christopher N Hahn et al.   NATURE GENETICS

Redefining CpG islands using hidden Markov models

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GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY