Article
Obstetrics & Gynecology
Lining Wang, Jingwen Zhang, Chengtian Zhao, Zhenzhen Jia, Xizeng Feng
Summary: HCPT has adverse effects on mouse oocyte maturation and quality, while MT administration alleviated the negative influence of HCPT.
REPRODUCTIVE SCIENCES
(2021)
Article
Reproductive Biology
Tianyi Lv, Beijia Cao, Jianpeng Qin, Yaozong Wei, Bo Pan, Jiangfeng Ye, Guangbin Zhou
Summary: This study investigates whether melatonin can modulate oxidative stress in parthenogenetic 2-cell embryos derived from vitrified-warmed oocytes through SIRT1. The results demonstrate that melatonin can reduce oxidative stress by regulating SIRT1 and promote the development of vitrified-warmed mouse MII oocytes.
Article
Pharmacology & Pharmacy
Peipei Qiao, Yingbing Zhang, Ying Yang, Ru Meng, Zhiming Xu, Xianlei Jiang, Yong Zhang, Chengtu Zhang, Jianmin Su
Summary: Isoniazid (INH) significantly impairs meiotic progression, increases oxidative stress, induces apoptosis, and disrupts mitochondrial function in mouse oocytes. These effects ultimately lead to reduced fertility and damage to the mammalian reproductive system.
Article
Reproductive Biology
Chenglin Zhan, Xu Cao, Tianrui Zhang, Jing Guo, Gaoqing Xu, Hongyan Wang, Wenyan Yang, Lianyu Yang, Dongsheng Che, Wenfa Lu, Xin Ma
Summary: This study investigated the effects of copper on porcine oocytes and revealed that copper leads to abnormalities in mitochondrial function and epigenetic modification, resulting in increased oxidative stress and levels of ROS, ultimately leading to decreased porcine oocyte quality. Melatonin can protect porcine oocytes from copper-induced damages, and copper activates the Nrf2 pathway, impairing oocyte maturation.
Article
Environmental Sciences
Yue Wang, Yao Xu, Jia-Qian Ju, Jing-Cai Liu, Shao-Chen Sun
Summary: This study found that exposure to FB1 affects the quality of mouse oocytes mainly by disrupting spindle structure, leading to dysfunction of mitochondria, lysosomes, and endoplasmic reticulum, and inducing oxidative stress, apoptosis, autophagy, and DNA damage in oocytes.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Food Science & Technology
Peramaiyan Rajendran, Abdullah M. Alzahrani, Vishnu Priya Veeraraghavan, Emad A. Ahmed
Summary: The study demonstrated that flavokawain A (FKA) can protect against endothelial injury induced by ochratoxin A (OTA) through the Nrf2 pathway and inhibition of NF kappa B, while also activating antioxidative and antiapoptotic signaling to prevent oxidative stress damage to endothelial cells.
Article
Biochemistry & Molecular Biology
Feifei Zhao, Sara Whiting, Sarah Lambourne, R. John Aitken, Ying-pu Sun
Summary: The study demonstrates that melatonin can protect human sperm from heat-induced oxidative stress by suppressing sperm mitochondrial ROS generation, increasing mitochondrial membrane potential, reducing lipid peroxidation product 4-HNE formation, and decreasing sperm DNA damage and apoptosis. This suggests melatonin as a potential treatment option for male infertility caused by heat-induced oxidative stress.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Rui Yan, Jie Ding, Yuanjie Wei, Qianlei Yang, Xiaoyun Zhang, Hairu Huang, Zhuoyue Shi, Yue Feng, Heran Li, Hengdong Zhang, Wenjun Ding, Yan An
Summary: Melatonin protects against NaAsO2-induced heart malformations in zebrafish by inhibiting oxidative stress and apoptosis.
Article
Immunology
Swaimanti Sarkar, Ankur Das, Ankan Mitra, Songita Ghosh, Sreya Chattopadhyay, Debasish Bandyopadhyay
Summary: This study found that adrenaline-copper complex can cause damage to cardiomyocytes, while melatonin can protect them. The results indicate that melatonin exerts cardioprotective effects through multiple mechanisms, including reducing oxidative stress, regulating inflammation, and inhibiting cell apoptosis.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Article
Environmental Sciences
Zhijie Yang, Yuqin He, Haifang Wang, Qiong Zhang
Summary: The study investigated the potential protective effect of melatonin (MT) against cadmium-induced hepatic injury. Results showed that MT exerts hepatoprotective effect by improving the redox state, suppressing inflammatory reaction and cell apoptosis, as well as ameliorating the histopathological variations of liver tissue.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Agriculture, Dairy & Animal Science
Sicong Yu, Lepeng Gao, Yang Song, Xin Ma, Shuang Liang, Hainan Lan, Xin Zheng, Suo Li
Summary: In this study, a mitochondrial damage model was induced in porcine oocytes with the Bcl-2-specific antagonist ABT-199, and the protective effects of glycine (Gly) against ABT-199-induced mitochondrial dysfunction were investigated. Gly was found to significantly ameliorate mitochondrial dysfunction, oxidative stress, and apoptosis, as well as regulate intracellular calcium levels and IP(3)R1 cellular distribution, thereby protecting oocyte maturation.
JOURNAL OF ANIMAL SCIENCE
(2021)
Review
Biochemistry & Molecular Biology
Magdalena Wieckowska, Rafal Szelenberger, Marcin Niemcewicz, Piotr Harmata, Tomasz Poplawski, Michal Bijak
Summary: Ochratoxin A (OTA) is a highly toxic mycotoxin produced by fungi, which commonly contaminates food and beverages, posing risks to animal and human health. The exact mechanism of OTA's toxicity and effective preventive measures are still not well understood, highlighting the need for further research.
Article
Agriculture, Dairy & Animal Science
Xiaoya Li, Jiaxin Duan, Shiyou Wang, Jianyong Cheng, Huali Chen, Zelin Zhang, Li Yang, Rongmao Hua, Qingwang Li
Summary: This study found that isorhamnetin can protect oocytes from damage caused by ZEA through the PI3K/Akt signaling pathway, improving developmental capability and inhibiting early apoptosis, oxidative stress, and endoplasmic reticulum stress.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2023)
Article
Environmental Sciences
Shaista Chaudhary, Upasana Sahu, Suhel Parvez
Summary: This study investigates the cellular mechanisms underlying VPA-induced neuronal cell death and the neuroprotective role of exogenous melatonin. The results show that melatonin pre-treatment protects cells from VPA-induced toxicity by regulating apoptotic proteins and pro-inflammatory cytokines, emphasizing novel insights of melatonin as a supplement for preventing and treating neuronal dysfunction induced by VPA.
ENVIRONMENTAL TOXICOLOGY
(2021)
Article
Pharmacology & Pharmacy
Shuang Chen, You Li, Shuai Fu, Yang Li, Chao Wang, Ping Sun, Hairu Li, Jiawei Tian, Guo-Qing Du
Summary: High levels of AVP induce cardiomyoblast apoptosis and mitochondrial dysfunction, while melatonin can reduce apoptosis and enhance antioxidative responses through the Mst1-Nrf2 pathway re-activation.
BIOCHEMICAL PHARMACOLOGY
(2022)
Review
Environmental Sciences
Attila Csaba Kondor, Anna Viktoria Vancsik, Laszlo Bauer, Lili Szabo, Zoltan Szalai, Gergely Jakab, Gabor Maasz, Marta Pedrosa, Maria Jose Sampaio, Ana Rita Lado Ribeiro
Summary: This review provides a critical overview of research on the removal efficiency of priority substances and compounds of emerging concern through bank filtration, discussing influencing factors and future challenges. The findings show that the efficiency of bank filtration is influenced by multiple factors and varies for different substances.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinyan Wang, Shuai Zhang, Huihui Yan, Zhao Ma, Yunshan Zhang, Haining Luo, Xueli Yang
Summary: This study investigated the association between ambient PM2.5, O3 pollution, and ovarian reserve in reproductive-aged Chinese women. The results showed that increased exposure to PM2.5 and O3 was associated with decreased AMH levels, indicating reduced ovarian reserve. Notably, the effects of O3 exposure on ovarian reserve were different from those of PM2.5 exposure.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Tingting Ma, Yanjuan Ding, Fengjiao Xu, Chen Zhang, Min Zhou, Ya Tang, Yanrong Chen, Yating Wen, Rufei Chen, Bin Tang, Shigui Wang
Summary: The dragonfly species Orthetrum albistylum can accumulate heavy metals, and its heat shock protein genes have the potential to serve as biomarkers for monitoring environmental pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Naoto Ishiwaka, Koya Hashimoto, Masayoshi K. Hiraiwa, Francisco Sanchez-Bayo, Taku Kadoya, Daisuke Hayasaka
Summary: Systemic insecticides and rising temperatures have combined effects on the abundance of Odonata nymphs in paddy fields. The standalone effect of insecticide exposure decreased the Odonata community, while nymphs decreased synergistically with temperature rise in paddy water. However, the impacts of each stressor alone varied among species.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Marco Vecchiato, Carlo Barbante, Elena Barbaro, Francois Burgay, Warren R. L. Cairns, Alice Callegaro, David Cappelletti, Federico Dallo, Marianna D'Amico, Matteo Feltracco, Jean-Charles Gallet, Andrea Gambaro, Catherine Larose, Niccolo Maffezzoli, Mauro Mazzola, Ivan Sartorato, Federico Scoto, Clara Turetta, Massimiliano Varde, Zhiyong Xie, Andrea Spolaor
Summary: The Arctic region is facing contamination from long-range pollution and local human activities. Polycyclic Aromatic Hydrocarbons (PAHs) are used as environmental indicators for emission, transport, and deposition processes. Research conducted in the Arctic surface snow in Ny-Ålesund, Svalbard from October 2018 to May 2019 shows that long-range inputs of PAHs mainly occur in winter, while the most abundant analyte retene exhibits opposite seasonal trends.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Maoshui Zhuo, Zhijie Chen, Xiaoqing Liu, Wei Wei, Yansong Shen, Bing-Jie Ni
Summary: This paper discusses the application of three catalytic processes (photocatalysis, electrocatalysis, and biocatalysis) in the management of microplastic pollution, and introduces the efficiency and catalytic mechanisms of different catalysts. It also proposes the development prospects for sustainable management of microplastic pollution.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Shiyu Chen, Zhenzhen Shi, Qiang Zhang
Summary: In this study, a human physiologically based pharmacokinetic (PBPK) model of diethyl phthalate (DEP) was developed to assess its toxicity. The model considers the distribution and metabolism of DEP and its active metabolite monoethyl phthalate (MEP) in different tissue compartments. Sensitivity analysis and Bayesian Markov chain Monte Carlo (MCMC) simulations were performed to evaluate the uncertainty and variability of the model parameters. The results suggest that dermal absorption is an important route of exposure to DEP in the environment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Bangguo Wang, Lijing Wang, Wenxi Cen, Tao Lyu, Peter Jarvis, Yang Zhang, Yuanxun Zhang, Yinghui Han, Lei Wang, Gang Pan, Kaili Zhang, Wei Fan
Summary: This study investigates the feasibility and mechanisms of a chemical-free nanobubble-based AOP for treating organic micropollutants in water. The results show that the oxygen nanobubble AOP has a significantly higher removal efficiency compared to air and nitrogen nanobubbles. The treatment performance is not affected by pH and the presence of ions. Higher initial concentrations of the micropollutant lead to slower treatment processes, but similar removal performance is achieved in the end. The presence of organic matter reduces the removal rate of the micropollutant. The results have practical feasibility for water and wastewater treatment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yingmei Huang, Jicai Yi, Yao Huang, Songxiong Zhong, Bin Zhao, Jing Zhou, Yuxuan Wang, Yiwen Zhu, Yanhong Du, Fangbai Li
Summary: This study investigates the impact of biochar on methylmercury (MeHg) accumulation in rice. The results show that biochar reduces MeHg levels in paddy soils by decreasing bioavailable Hg and microbial Hg methylation. Additionally, biochar decreases the uptake and translocation of MeHg in rice plants, resulting in a reduction of MeHg accumulation in rice grains.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Nengde Zeng, Fei Huang, Jiani Du, Chenghao Huang, Qian Yang, Xinhua Zhan, Baoshan Xing
Summary: This study investigates the protein targets and protein-ligand interactions related to PAH contamination in crop xylem sap using computational tools. The results show that phenanthrene has a more pronounced effect on the xylem sap proteins of maize and wheat, with maize DEPs associated with lipid biosynthesis and wheat DEPs exhibiting an increase in ABC transporters. This study provides insights into the regulation and movement of PAHs within plant xylem.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinwei Chen, Hao Ma, Run Wang, Man Wang, Binbin Zhu, Yanqing Cong, Xiayue Zhu, Guoqin Wang, Yi Zhang
Summary: Co3O4/TiO2-NRs electrodes with excellent photoresponse were prepared via plasma-assisted modification of Co3O4 on TiO2. The combination of Co3O4 and TiO2 improved the light utilization efficiency and showed potential for degradation of pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Wenjing Ji, Liying Song, Jing Wang, Hongqing Song
Summary: This study conducted a life-cycle assessment to examine the correlation between natural gas consumption and carbon emissions in different end uses in China. The results showed that both natural gas consumption and life-cycle carbon emissions have been increasing since 2017. Significant variations in NG life-cycle carbon emissions were found across different provinces and sectors, highlighting the need for targeted efforts to reduce carbon emissions.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Youyi Chen, Boxuan Zhang, Pojun Zhang, Guogui Shi, Hao Liang, Wu Cai, Jingyu Gao, Sumin Zhuang, Kaiyin Luo, Jiaqi Zhu, Chaoxiang Chen, Kunyu Ma, Jinrong Chen, Chun Hu, Xueci Xing
Summary: The synergistic effects of trace sulfadiazine and cast-iron corrosion scales on the formation of disinfection by-products in drinking water distribution systems were investigated. The presence of magnetite resulted in increased concentrations of DBPs due to the higher microbial activity and enhanced microbial extracellular electron transport pathway. The study highlights the importance of considering trace antibiotics pollution and corrosion scales in water sources for DBP control.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Bishwa Raj Pokharel, Vijay Sheri, Manoj Kumar, Zhiyong Zhang, Baohong Zhang
Summary: This review summarizes the interactions, uptake, and transport of aluminum nanoparticles (Al-NPs) in plants, highlighting their negative effects on plant growth and development, as well as their potential to alter plant defense systems and gene expression.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yonglu Wang, Fengsong Zhang, Xiaoyong Liao, Xiao Yang, Guixiang Zhang, Liyun Zhang, Chaojun Wei, Pengge Shi, Jiongxin Wen, Xiaorong Ju, Can Xu, Yang Liu, Ying Lan
Summary: This study aims to explore the effects of thiencarbazone-methyl center dot isoxaflutole on soil microflora and the potential mitigation mechanisms to bacterial communities. It was found that increasing the application of thiencarbazone-methyl center dot isoxaflutole resulted in increased stress on soil bacterial community structure and diversity. Increasing soil pH was recognized as a key factor in improving the diversity and structure of soil microflora. Supplemental use of nitrapyrin or modified attapulgite can increase soil pH and improve bacterial diversity.
ENVIRONMENTAL POLLUTION
(2024)