Review
Chemistry, Analytical
Muthaiah Shellaiah, Kien Wen Sun
Summary: Biothiols, such as cysteine, homocysteine, and glutathione, play a crucial role in various biological processes, but abnormal levels can lead to serious diseases. Carbon-dots (CDs) have emerged as a promising tool for biothiols quantification due to their easy synthesis, nanosize, low toxicity, and real-time applicability. However, a comprehensive review on fluorescent CDs-based biothiols detection is lacking. This review provides valuable information on the assays, mechanisms, applications, selection of probes/CDs, sensory requirements, merits, limitations, and future prospects.
Article
Spectroscopy
Nayomi Camilus, Stephanie Gao, Musonda Mitti, Jun-Ray Macairan, Rafik Naccache, Sanela Martic
Summary: The post-translational modification of amino acids plays a critical role in normal and diseased biological states. This study achieved selective detection of nitrotyrosine (nTyr) using dual-fluorescent carbon dots (CDs), even in the presence of common biological interferences. These findings highlight the potential of CDs as viable sensors for key biological modifications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Review
Chemistry, Applied
Yongming Guo, Ruiqing Wang, Chengwei Wei, Yijin Li, Tiancheng Fang, Tao Tao
Summary: NO2- is commonly found in foods and the environment, and excessive intake poses serious hazards to human health. Traditional instrumental approaches for detection of NO2- are limited by expensive instruments and complicated operations. The emergence of carbon quantum dots (CQDs) provides a solution with their integrated merits, including easy fabrication, low-cost, high quantum yield, excellent photostability, tunable emission behavior, good water solubility, and low toxicity. This review presents the synthetic strategies of CQDs and highlights their advances in fluorescent detection of NO2-, while also discussing the challenges and perspectives in the field.
Article
Chemistry, Physical
Jiaying Zhao, Junsheng Yang, Yi Ma, Dong Zhao, Huibo Luo, Xiaogang Luo, Changjun Hou, Danqun Huo
Summary: A Fe3+-triggered multifunctional nitrogen-doped carbon quantum dots (N-CQDs) on-off-on fluorescent sensing platform was successfully established for the ultrasensitive detection of biothiols (GSH, Cys and Hcy). The fluorescence of N-CQDs was quenched by Fe3+ through coordination, but recovered after the addition of biothiols due to stronger coordination between Fe3+ and biothiols. The platform exhibited a relatively lower limit of detection and showed good anti-interference ability, reproducibility, and repeatability in serum samples.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Green & Sustainable Science & Technology
Gwajeong Jeong, Chan Ho Park, Dongchan Yi, Hyunseung Yang
Summary: This study presents a sustainable, high throughput method for producing uniform carbon dots using spent coffee grounds via a simple wet ball-milling process. The versatility of this approach extends to the synthesis of heteroatom-doped carbon dots and the preparation of carbon dots from various sources of spent coffee grounds. Manipulating the functional groups of the carbon dots through the addition of citric acids during the ball-milling process, carboxylic acid-functionalized carbon dots were produced. These carbon dots exhibited highly selective and sensitive detection of Fe3+ ions in aqueous solution, and the relevant quenching mechanism was investigated. Additionally, a fluorescent microgel sensor was demonstrated to exhibit a rapid, ratiometric fluorescence change upon the addition of Fe3+ ions by encapsulating the carboxylic acid-functionalized carbon dots within the microgel matrix.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Biochemistry & Molecular Biology
Pingping Liu, Lu Ga, Yong Wang, Jun Ai
Summary: Water-soluble nitrogen-doped carbon dots (N-CDs) with excellent optical and fluorescence thermal properties were prepared by the hydrothermal method using 4-dimethylaminopyridine and N,N'-methylenebisacrylamide as precursors. Co2+ selectively burst the fluorescence of N-CDs, showing high sensitivity and detection limit. In addition, the N-CDs' temperature response and optical properties make them potential candidates in the field of fluorescent inks and temperature sensing.
Review
Chemistry, Multidisciplinary
Vinay Sharma, Pranav Tiwari, Navpreet Kaur, Shaikh M. Mobin
Summary: The increasing contamination of environmental media poses a serious health issue that requires advanced methods for detecting pollutants. Carbon dot sensors show unique advantages in detecting contaminants in water samples, with high sensitivity and wide applicability.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Xinglei He, Huijun Li, Jiwei Wang, Yanli Li, Meijie Su, Zhouqing Xu
Summary: This study introduced a multifunctional luminescent material with multiple luminescence modes, which is sensitive and reversible to HCl gas and can be used as anti-counterfeiting ink. The material can obtain specific stored information under different excitations and can repeatedly read hidden information when treated with acid/base vapor.
CRYSTAL GROWTH & DESIGN
(2021)
Article
Chemistry, Analytical
Piyali Sabui, Sadhucharan Mallick, Kshitij R. B. Singh, Arunadevi Natarajan, Ranjana Verma, Jay Singh, Ravindra Pratap Singh
Summary: Food safety and quality is a significant research area globally. The development of high-performance sensors based on carbon nanomaterials has made notable progress in food safety investigation. This review summarizes different detection approaches and the integration of carbon nanomaterials with optical sensors for identifying multiple contaminants in food products.
Article
Biochemical Research Methods
Xiaoxiao Gao, Yan Zhang, Zheng Fu, Fengling Cui
Summary: In this paper, carbon dots (CDs) with strong blue fluorescence were successfully synthesized through hydrothermal method. The prepared CDs showed excellent fluorescence properties and stability. The presence of Hg2+ selectively quenched the fluorescence of CDs, which could be recovered with the introduction of biothiols. Moreover, there was a good linear relationship between the fluorescence of CDs and the concentration of Hg2+, with a low detection limit.
JOURNAL OF FLUORESCENCE
(2022)
Review
Chemistry, Inorganic & Nuclear
Wenjuan Liu, Jie Chen, Zhaochao Xu
Summary: Biothiols are small molecules with vital physiological functions, and their detection is mainly achieved by changing the fluorescence emission of fluorophores through the nucleophilic reaction ability of sulfhydryl groups. In recent years, many fluorescent probes recognizing biothiols based on the coordination ability of sulfhydryl groups and metals have been reported. The review of progress in this field is deemed timely and essential.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Analytical
Xiaoping Chen, Yafeng Zhuang, Jing Chen, Jianwei Lin, Jinghua Chen, Zhizhong Han
Summary: Novel norepinephrine modified carbon dots (NECDs) were prepared and showed improved fluorescence properties compared to unmodified carbon dots (CDs). A dual-mode sensing platform based on NECDs was developed for the detection of Cu2+ and biothiols, which exhibited high sensitivity and selectivity through fluorescence resonance energy transfer and absorption changes.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Xiu Ye, Dongyang Zhang, Sai Wang, Peng Zhou, Pengli Zhu
Summary: The study demonstrates that tetraphenylethylene-based fluorescent cellulose nanocrystals exhibit excellent fluorescence properties and high selectivity and sensitivity for detecting nitrophenol explosives and Fe3+ in aqueous solutions.
Article
Engineering, Environmental
Lin Luo, Shi-Qi Lin, Zhuo-Yu Wu, Hong Wang, Zi-Jian Chen, Hao Deng, Yu-Dong Shen, Wen-Feng Zhang, Hong-Tao Lei, Zhen-Lin Xu
Summary: A nanobody-alkaline phosphatase fusion protein-based fluorescent ELISA method was developed for highly sensitive detection of fenitrothion (FN) residue in food. The detection limit of this method was 0.14 ng mL-1, which is 25-fold lower than that of conventional colorimetric ELISAs.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Analytical
Saeedeh Narimani, Naser Samadi
Summary: Novel highly fluorescent carbon dots were synthesized from chicken waste through a green, low-cost hydrothermal method. These carbon dots exhibited blue fluorescence with a high quantum yield and excellent selectivity for detecting ceftriaxone. This simple and economical method proved to be reliable for rapid determination of ceftriaxone in spiked urine samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Hao Zhang, Chen Nie, Jiahui Wang, Ruifang Guan, Duxia Cao
Article
Nanoscience & Nanotechnology
Hao Zhang, Xuezhe Dong, Jiahui Wang, Ruifang Guan, Duxia Cao, Qifeng Chen
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Optics
Hao Zhang, Jiajian You, Chen Nie, Jiahui Wang, Xuezhe Dong, Ruifang Guan, Duxia Cao, Qifeng Chen
JOURNAL OF LUMINESCENCE
(2019)
Article
Materials Science, Multidisciplinary
Hao Zhang, Zihan Yuan, Mingkun Wang, Lin Zhu, Xiao Cheng, Duxia Cao, Ruifang Guan, Chuanjian Zhou
Summary: Graphene quantum dots with a simple structure can serve as excellent probes for detecting Hg2+ and ClO in aqueous solution.
DIAMOND AND RELATED MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Lin Zhu, Xin Chen, Ruirui Shi, Hao Zhang, Rui Han, Xiao Cheng, Chuanjian Zhou
Summary: The study synthesized tetraphenylphenyl-modified damping additives and investigated their effects on the mechanical and morphological properties of silicone rubber. Experimental results demonstrated significant improvements in damping performance while maintaining excellent mechanical properties. Molecular dynamics simulations revealed that enhanced intermolecular interactions and steric hindrance were crucial factors for enhancing damping performance.
MATERIALS & DESIGN
(2021)
Article
Spectroscopy
Yunqian Ma, Hao Zhang, Kexin Wang, Duxia Cao, Mingkai Wang, Ruifang Guan, Chuanjian Zhou
Summary: This study introduces a biomimetic fluorescent molecule CA-AEP with a dipeptide structure that emits bright biomimetic fluorescence in aqueous solutions by adjusting the pH, a characteristic explained by the clustering-triggered emission (CTE) mechanism. CA-AEP can also be used to monitor the maximum dynamic pH in alkaline aqueous systems, and cytotoxicity assays show it is non-toxic to A549 cells. This work provides a new type of luminogen with potential applications in environmental monitoring and cell biology.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Polymer Science
Zhe Liu, Yuqi Xiong, Jinghao Hao, Hao Zhang, Xiao Cheng, Hua Wang, Wei Chen, Chuanjian Zhou
Summary: A novel liquid crystal-based organosilicon elastomer with supreme mechanical adaptability and tunable tensile strength is developed. Compared to conventional silicone rubbers, this elastomer can effectively inhibit stress increasing during deformation, exhibiting better tensile properties. It also maintains stability over a wide temperature range.
Article
Chemistry, Physical
Hao Zhang, Chen Nie, Duxia Cao, Xiao Cheng, Ruifang Guan
Summary: Recently, unconventional fluorescent compounds without conventional chromophores have gained significant attention. This paper utilized the imidazoline ring, an unconventional chromophore, as the raw material for constructing fluorescent molecules. The fluorescence of the molecules was found to be greatly increased when acetic acid was introduced. The study also analyzed the impact of clusters of aggregated oxygen atoms on molecular fluorescence by examining the change in fluorescence in the crystal and solution states. Additionally, the applications of the imidazoline compound and its ionic liquid in metal ion recognition, pH sensing, and fluorescent staining in living cells were explored.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Polymer Science
Wenlu Su, Hao Zhang, Shaohua Yang, Yushu Xu, Chengpeng Zhang, Xiao Cheng, Chuanjian Zhou
Summary: A Dual-D-4(Vi) monomer is designed for one-pot synthesis of multifunctional silicone elastomer, functioning both as monomer and cross-linker. This method offers a simple and efficient way of preparing silicone elastomer with wide applicability, fast polymerization rate, and controllable viscosity and polymerization.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Biochemical Research Methods
Ning Du, Hao Zhang, Jiahui Wang, Xuezhe Dong, Jinqiu Li, Kexin Wang, Ruifang Guan
Summary: Green synthetic silicon nanoparticles were synthesized and used for free hemin detection in serum. The results confirmed that multiple redox centers of hemin led to enhanced dynamic quenching, and the inner filter effect also played a role in the quenching.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Hao Zhang, Ludan Qin, Duxia Cao, Ruifang Guan, Xiao Cheng, Chuanjian Zhou
Summary: In recent years, the challenge of achieving a high quantum yield (QY) in dilute solutions of non-aromatic fluorescent materials has received widespread attention. This study successfully designed a bioinspired molecule with a dipeptide-like structure and active silanol groups, inspired by the Clustering-triggered emission (CTE) phenomenon. The hydrolysate hPDs obtained by simple heating of the bioinspired molecule can emit strong blue fluorescence in dilute solution, and this is the first time that the emission behavior of non-aromatic fluorescent materials has been realized under sunlight. The high QY of h-PDs in aqueous solution and solid state, attributed to the condensation of active silanol groups and the presence of hydrogen bonds and N-Si coordination bonds, allows small molecules to cross-link and aggregate into dense clusters.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Hao Zhang, Duxia Cao, Xiao Cheng, Ruifang Guan, Chuanjian Zhou
Summary: This article describes a novel and simple approach of using amide salt pyrolysis to produce photoluminescent graphene nanosheets with a thickness of <1 nm and a diameter of about 100-200 nm. The method has characteristics of high water solubility, low toxicity, easy manufacturing, etc., and has potential application prospects in analytical chemistry and biomedicine.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Analytical
Ke-Xin Wang, Chen Nie, Rui-Fang Guan, Hao Zhang
Summary: Unconventional fluorescent molecules without conjugated rings have gained significant attention in recent years due to their excellent fluorescence properties, simple preparation process, good water solubility, and excellent biocompatibility. This study presents a new strategy to construct dual emission fluorescent probes using unconventional fluorescent molecules and fluorescein isothiocyanate. The resulting polymer dots exhibit two fluorescence emission peaks under excitation, allowing for the quantitative detection of Cu2+ and ClO-. The method demonstrates high detection sensitivity and linear fluorescence quenching.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Ruifang Guan, Baoli Dong, Cui Xu, Hao Zhang, Duxia Cao, Weiying Lin
CHEMICAL COMMUNICATIONS
(2020)
Article
Chemistry, Applied
Leping Chen, Yanfen Wang, Tingyu Shi, Tiantian Ma, Yang Li, Huayu Qiu, Shouchun Yin, Meier Gu
Summary: This study successfully overcame the limitations of the heavy atom effect by introducing iodine atoms and innovatively enhancing the structure while weakening stacking behavior, achieving high efficiency and precision in photodynamic therapy and photothermal therapy.
Article
Chemistry, Applied
Bingpeng Guo, Honghan Sa, Peng Zhang, Guiwen Hao, Mengyu Li, Qingqing Jiang, Baoying Li, Wei Shu, Changxiang Shao
Summary: The design of ratiometric fluorescence probes with large Stokes shift is of great significance in detecting and imaging target substances in complex organisms. In this study, a novel fluorophore with a large Stokes shift was easily obtained, and a fluorescence probe based on it demonstrated rapid response, high selectivity, and sensitivity towards peroxynitrite. The probe also showed excellent biocompatibility and remarkable mitochondrial targeting ability, making it suitable for proportional imaging of peroxynitrite in living cells and zebrafish.
Review
Chemistry, Applied
Haidong Huang, Xiaohui Wang, Xinyang Li, Yichen Li, Guojin Liu, Lan Zhou, Jianzhong Shao
Summary: This article introduces the application of responsive photonic crystals in anti-counterfeiting technology, with a focus on the preparation principle, classification, and preparation methods.
Article
Chemistry, Applied
Yunpeng Wang, Tao Zhao, Xiaoye Bi, Chencheng Lv
Summary: In this study, three novel carbene dyes were designed to achieve environmentally friendly dyeing processes. The dyes formed covalent bonds with fibers and exhibited good dyeing performance and high color fastness. These findings highlight the potential of the novel carbene dyes in promoting green production in the textile industry.
Review
Chemistry, Applied
Yizhe Yan, Xiaopei Zhu, Jia-Xin Cao, Yuan He, Shaoqing Li, Jian-Yong Wang
Summary: In this paper, 1,3,5-triazine dyes were successfully synthesized and their photophysical properties were studied. Two probes were selected for further investigation, showing promising applications in various fields.
Article
Chemistry, Applied
Xin Hu, Tongsheng Huang, Lihua Chen, Weifeng Zhu, Fengjie Deng, Xiancai Li, Jianwen Tian, Meiying Liu, Xiaoyong Zhang, Yen Wei
Summary: This study presents the synthesis of fluorescent cyclomatrix polyphosphazene spheres with aggregation-induced emission (AIE) feature and biodegradable potential for controlled drug delivery. The resulting micelles exhibit high water dispersibility, desirable fluorescence performance, and high drug loading capacity. They can effectively release the encapsulated drug in physiological solution and show excellent biological imaging ability and cytotoxicity against cancer cells.
Article
Chemistry, Applied
Yanzhu Liu, Yanghui Lei, Dongyan Li, Guangkui Li, Dongping Li, Yongxiu Li
Summary: In this study, luminescent lanthanide nanoparticles were synthesized as a dual emission turn-off probe for detecting 2,6-pyridinedicarboxylic acid (DPA) in water. The nanoparticles showed good dispersion and water stability, and achieved low detection limits for DPA. They also exhibited high recoveries in various samples.
Article
Chemistry, Applied
Jung Jae Do, Jong Ryeol Kwon, Donghan Kim, Jae Woong Jung
Summary: This study presents a defect passivation approach using coumarin dye as a multi-functional passivating agent of perovskite films to boost power conversion efficiency and operating stability of PSCs. The incorporation of coumarin dye improves the film morphology, enhances carrier extraction/transport, and suppresses trap-assisted recombination in the perovskite films. The optimized device demonstrates impressive reliability and practical applicability, maintaining over 90% of its initial PCE after being exposed to continuous indoor lighting irradiation for 2000 hours.
Article
Chemistry, Applied
Gang Wang, Yu-Chang Wang, Jing Lu, Wen-Fu Yan, Juan Jin, Yuan-Peng Wang, Jia-Jia Zhang, Hui-Jie Zhang, Hao Dong, Xi-Guang Liu
Summary: A new Ni(II) compound with good solid-state fluorescence performance and stability was synthesized, and it showed outstanding detection properties for various substances in aqueous solutions. This compound has the potential to be a multifunctional sensor.
Article
Chemistry, Applied
Luyao Wei, Shenglong Shang, Yu Zheng, Jie Liu, Ping Zhu
Summary: This study developed a facile method to create high saturation and durable structural colors on cotton fabrics. The colors are regulated by adjusting the size of magnetic particles and can be conveniently printed on fabrics using photo masks on transparent films.
Article
Chemistry, Applied
Zhao Jiang, Qing Zhang, Zhaoyu Kong, Ruijie Qiao, Zichuan Liu, Linzhou Song, Senqiang Zhu, Rui Liu, Hongjun Zhu
Summary: Three heteroleptic Ir(III) complexes with different electron-donating aryl groups were synthesized and their optical properties were investigated. It was found that all three complexes exhibited aggregation-induced phosphorescence emission (AIPE) behaviors, and the relationship between the size of organic ligands and AIPE behaviors was characterized. Ir-PhCz showed the best imaging of latent fingerprints due to its green light emission and high quantum yield.
Article
Chemistry, Applied
Zhijun Ruan, Chunxia Fan, Xuanrong Wang, Dong Shao, Xiaodong Yang, Wentao He, Tao Xu, Junqi Lin, Zhengfang Tian
Summary: A novel thioketal-based probe has been designed for rapid and accurate detection of mercury (II) ions, showing different fluorescence characteristics in various states. The probe exhibits excellent selectivity and specificity, making it suitable for Hg2+ detection in water solutions.
Article
Chemistry, Applied
Jianjun Huang, Xuan Zhao, Daniel Escudero, Luc Van Meervelt, Dongbin Zheng, Yuyu Fang, Wim Dehaen
Summary: A series of BOAHY compounds were successfully synthesized and showed versatile applications as a platform for designing novel fluorescent probes, especially in selective recognition.
Article
Chemistry, Applied
Roman V. Larkovich, Victoria E. Shambalova, Savva A. Ponomarev, Alexander S. Aldoshin, Boris N. Tarasevich, Konstantin A. Lyssenko, Valentine G. Nenajdenko
Summary: An efficient synthetic protocol for the preparation of novel 1,7-difluorinated BODIPYs was elaborated. Their photophysical properties were studied and the effect of 2,6-substituents was evaluated using DFT calculations.
Article
Chemistry, Applied
Haneul Kim, Byungjin Koo
Summary: In this study, a lithium ion sensing methodology based on fluorinated naphthalene compounds using 19F NMR and UV-vis spectroscopy is reported. The binding of lithium ions to the compounds is confirmed by changes in chemical shifts and peak broadening. Additionally, the effect of different crown ether ring sizes on the binding ability is observed. This study provides a new method for lithium ion sensing using spectroscopy.