Editorial Material
Geosciences, Multidisciplinary
Jonathan M. Pownall, Kathryn A. Cutts
Summary: Jon Pownall and Kathryn Cutts delve into the past and future implications of garnet as a valuable tool for measuring pressure, temperature, and time.
Editorial Material
Biochemistry & Molecular Biology
Neil A. Hanchard, Ananyo Choudhury
Summary: This article discusses the release of expanded high-depth sequencing data for the fourth phase of the 1000 Genomes Project. It explores how this dataset can serve as a more comprehensive and accurate resource for global genomics through extensive comparisons and benchmarks.
Review
Hematology
Bjorn Dahlback
Summary: The complex reactions of blood coagulation are balanced by natural anticoagulants, including antithrombin, activated protein C (APC), thrombomodulin, and factor V (FV). These anticoagulants play important roles in regulating hemostasis and preventing thrombosis. The discovery of new anticoagulants, such as FV-Short, provides valuable insights into the mechanisms of blood coagulation and has implications for understanding and treating bleeding disorders.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2023)
Review
Chemistry, Multidisciplinary
Elena Boldyreva
Summary: Despite its small size and achirality, glycine exhibits diverse behaviors across different phenomena. Research on glycine highlights the critical importance of phenomena at interfaces in areas such as crystal growth, dissolution, and physical properties.
ISRAEL JOURNAL OF CHEMISTRY
(2021)
Editorial Material
Hematology
Mitchell S. Cairo
Summary: In this study, it was found that the Epstein-Barr virus (EBV) is linked to immune deficiency associated lymphoproliferative disorders (IA-LPD) in children with acute lymphoblastic leukemia (ALL). EBV, also known as human herpesvirus 4 (HHV-4), is a member of the gammaherpesvirus group and is highly prevalent, infecting 80% to 95% of the human population. While immunocompetent individuals, especially young children, are usually asymptomatic during primary EBV infection, adolescents and young adults often experience symptoms of infectious mononucleosis.
Article
Fisheries
Monal M. Lal, Salote S. Waqairatu, Kyall R. Zenger, Maria G. Nayfa, Timothy D. Pickering, Avinash Singh, Paul C. Southgate
Summary: Genetic analysis of the GIFT strain of Nile tilapia in Fiji revealed mild declines in genetic diversity, with some ponds showing signs of reduced effective population size and allelic diversity. Management practices and potential wild interbreeding were identified as factors influencing genetic structure and relatedness within the broodstock nucleus. Regular genetic monitoring and evaluation of performance are recommended to preserve valuable genetic diversity in the long term.
Article
Communication
Donyale Griffin R. Padgett, Lindsay Toman, Annisa M. P. Rochadiat, Vinita Parekh
Summary: This article reflects on the experience of conducting a qualitative study through focus group interviews to explore organ and tissue donation attitudes among African Americans, Arab Americans, and Hispanic-Latinx people in Southeast Michigan. The importance of conducting in-depth qualitative research to understand religious and cultural barriers to donation and to inform evidence-based campaigns for organ and tissue donation among ethnoracial minorities is emphasized in this study.
HOWARD JOURNAL OF COMMUNICATIONS
(2023)
Article
Business, Finance
Jennifer L. Brown, G. Ryan Huston, Brian S. Wenzel
Summary: This study examines the overlooked type of insider transaction where CEOs gift stocks to family members. The findings suggest that these CEO freeze gifts typically occur after temporary price suppressions and before significant price appreciation, resulting in substantial estate tax savings. Furthermore, positive market returns are observed one and two years following the disclosure of these gifts.
REVIEW OF ACCOUNTING STUDIES
(2022)
Review
Biochemistry & Molecular Biology
Adrian Boicean, Victoria Birlutiu, Cristian Ichim, Paula Anderco, Sabrina Birsan
Summary: Inflammatory bowel diseases (IBD) are complex diseases characterized by chronic inflammation in the gastrointestinal tract. Fecal microbiota transplantation (FMT) has shown increasing effectiveness and safety in treating recurrent Clostridium difficile infection (CDI) and co-infection of SARS-CoV-2 and CDI. By modifying the gut microbiota, FMT offers an alternative approach to indirectly influence the host's immune system in a safe way, improving clinical symptoms and endoscopic findings in IBD patients. Further validation is needed to establish a clinical protocol for FMT in IBD.
Review
Biochemistry & Molecular Biology
Adrian Boicean, Victoria Birlutiu, Cristian Ichim, Olga Brusnic, Danusia Maria Onisor, Amedeo Amedei, Ryota Niikura
Summary: Imbalances in the gut microbiota play a crucial role in the development of liver diseases, and fecal microbiota transplantation has shown promise as an effective treatment for chronic liver diseases and cirrhosis.
Review
Biochemistry & Molecular Biology
Catia Almeida, Rita Oliveira, Pilar Baylina, Ruben Fernandes, Fabio G. Teixeira, Pedro Barata
Summary: The disturbance of gut microbiota is correlated with various diseases, and fecal microbiota transplantation (FMT) has emerged as a potential therapeutic tool. FMT involves introducing fecal material from a healthy donor into the patient's gastrointestinal tract to restore gut microbiota. However, FMT may have side effects such as diarrhea and abdominal pain. This review summarizes the recent advances in understanding FMT mechanisms and its impact on different pathological conditions, as well as the associated side effects.
Review
Gastroenterology & Hepatology
Rohma Ghani, Benjamin H. Mullish, Lauren A. Roberts, Frances J. Davies, Julian R. Marchesi
Summary: Disruption to the intestinal microbiota increases the risk of infection, and restoring its composition is a potential strategy to mitigate this risk. Fecal microbiota transplantation is currently the major therapeutic approach, with potential use in treating other infectious diseases.
Article
Hematology
Melissa K. Hyde, Barbara M. Masser, Lianne Spears
Summary: Blood collection agencies hosting stool donor programs often defer a high percentage of potential donors, resulting in the loss of future eligible donors. This study explored the experiences of ineligible donors and found that many did not know the reason for their ineligibility, leading to permanent loss of potential donors. Motives for donation included altruism, curiosity, and a desire to contribute to scientific research.
Article
Gastroenterology & Hepatology
Jessica R. Allegretti, Shama R. Mehta, Zain Kassam, Colleen R. Kelly, Dina Kao, Huiping Xu, Monika Fischer
Summary: This study reviewed data of patients who underwent at least one FMT for CDI, and found that risk factors for failing a second FMT include inpatient status, presence of pseudomembranes, and immunocompromised state.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Immunology
Jiuxi Liu, Jiapei Cai, Naisheng Zhang, Jiandong Tai, Peng Fan, Xue Dong, Yongguo Cao
Summary: Salidroside, a plant compound, can ameliorate high-fat diet-induced obesity by modulating gut microbiota. It reduces body weight and fat accumulation, decreases liver inflammation and metabolic endotoxemia, and repairs intestinal damage.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Review
Gastroenterology & Hepatology
Harleen Chela, Syed Bilal Pasha, Xiu-Feng Wan, Yezaz A. Ghouri
Summary: The COVID-19 pandemic has raised concerns about the management of high-risk patients, including those with compromised immune systems, especially individuals with inflammatory bowel disease. Limited data and suggestions from medical societies aim to minimize the risk of infection in these patients during the ongoing pandemic.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Endocrinology & Metabolism
Mary Mikhael, Bilal Pasha, Harleen Chela, Veysel Tahan, Ebubekir Daglilar
Summary: This review article discusses the immunological and metabolic changes associated with esophageal cancer, as well as the multifactorial mechanisms that contribute to the development of this disease.
ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS
(2022)
Editorial Material
Surgery
Ebubekir Daglilar, Harleen Kaur Chela, Omer Basar, Veysel Tahan
Review
Endocrinology & Metabolism
Burak C. C. Sevim, Harleen Chela, Hamza Ertugrul, Lyiba S. S. Malik, Suha Malik, Omer Basar, Ebubekir Daglilar, Sami Samiullah, Ayman H. H. Gaballah, Veysel Tahan
Summary: Non-alcoholic fatty pancreas disease (NAFPD) is a relatively new and emerging disease that is associated with metabolic syndrome and obesity. While the definitive treatment is not yet established, weight loss is the primary approach. Further research is needed to explore the pathophysiology, clinical impact, and management of NAFPD.
ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS
(2023)
Letter
Medicine, General & Internal
Umer Farooq, Zahid Tarar, Muddasir Ashraf, Veysel Tahan, Ebubekir Daglilar
MAYO CLINIC PROCEEDINGS
(2023)
Letter
Medicine, General & Internal
Fan-Yun Lan, Stephen D. Kasteler, Amalia Sidossis, Eirini Iliaki, Jane Buley, Neetha Nathan, Rebecca Osgood, Lou Ann Bruno-Murtha, Stefanos N. Kales
MAYO CLINIC PROCEEDINGS
(2023)
Article
Pharmacology & Pharmacy
Mohamad Yousef, Harleen Chela, Hamza Ertugrul, Abdulmajeed Albarrak, Omer Basar, Syed Pasha, Yousef Mousa, Alhareth Al Juboori, Shellaine Frazier, Veysel Tahan, Ebubekir Daglilar
Summary: Background: Lymphocytic esophagitis (LE) is a poorly understood clinical finding that has been increasingly identified in the last decade. Previous studies proposed increased frequency of LE in elderly females, as well as associations with smoking and pediatric Crohn's disease. Objective: This study aimed to determine the patient characteristics and clinical features of adult LE patients and describe the association between LE and cancer. However, no cases of malignant transformation have been reported in those with underlying lymphocytic esophagitis.
RECENT ADVANCES IN INFLAMMATION & ALLERGY DRUG DISCOVERY
(2023)
Review
Medicine, Research & Experimental
Zahid Ijaz Tarar, Umer Farooq, Mustafa Gandhi, Faisal Kamal, Moosa Feroze Tarar, Veysel Tahan, Harleen Kaur Chela, Ebubekir Daglilar
Summary: There is increasing evidence of the association between Microscopic Colitis (MC) and the use of certain medications such as PPIs, SSRIs, NSAIDs, Statins, and H2RA. A study was conducted to calculate the pooled odds of MC in patients using these drugs. Thirteen studies with a total of 304,482 patients were included in the analysis. The results showed higher odds of MC in patients taking PPIs, SSRIs, NSAIDs, and Statins compared to the control group, but no difference in odds of MC in patients using H2RA.
Review
Medicine, Research & Experimental
Mustafa Gandhi, Syed Bilal Pasha, Emily Reznicek, Syed Raheel Pasha, Hamza Ertugrul, Adel Araslanova, Feng Yin, Veysel Tahan
Summary: Light chain deposition disease (LCDD) is a rare monoclonal immunoglobulin deposition disease that primarily affects the kidney but can also involve the liver and heart. This article presents a case of an 83-year-old woman with hepatic LCDD and highlights the challenges in timely diagnosis and treatment due to the rarity of the condition and limited data. The prognosis for liver failure in LCDD is poor, and while chemotherapy options are available, their success rates vary. The low prevalence of the condition makes further clinical trials difficult.
Review
Medicine, Research & Experimental
Zeynep Deniz, Suleyman Uraz, Ryan Holem, Resat Ozaras, Veysel Tahan
Summary: The human papillomavirus (HPV) is a common sexually transmitted infection with a 50% lifetime risk of infection for both men and women. While most infections resolve within 2 years, 10% of individuals develop persistent infections and have an increased risk of developing cancer. HPV is well established to be associated with genital cancer and may also be associated with gastrointestinal cancers.
Review
Medicine, Research & Experimental
Harleen Kaur Chela, Karthik Gangu, Hamza Ertugrul, Alhareth Al Juboori, Ebubekir Daglilar, Veysel Tahan
Summary: Esophageal cancer is a devastating malignancy with diverse underlying factors, including inflammation. Diagnosis is based on clinical symptomatology, imaging, and endoscopy, and treatment and prognosis depend on the disease stage.
Article
Medicine, Research & Experimental
Karthik Gangu, Aniesh Bobba, Harleen Kaur Chela, Omer Basar, Robert W. Min, Veysel Tahan, Ebubekir Daglilar
Summary: Untreated biliary tract diseases during hospitalization can lead to worse outcomes. Our study reveals that postponing definitive management to a subsequent visit is associated with higher 30-day readmission rates, increased mortality rates, and added financial burden for patients.
Review
Pharmacology & Pharmacy
Maliha Naseer, Shiva Poola, Suleyman Uraz, Veysel Tahan
CURRENT CLINICAL PHARMACOLOGY
(2020)
Review
Pharmacology & Pharmacy
Maliha Naseer, Shiva Poola, Syed Ali, Sami Samiullah, Veysel Tahan
CURRENT CLINICAL PHARMACOLOGY
(2020)
Review
Medicine, Research & Experimental
Hakan Akin, Ramazan Kurt, Fatih Tufan, Ahmed Swi, Resat Ozaras, Veysel Tahan, Ghassan Hammoud
