Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug–Drug Interaction Studies
出版年份 2020 全文链接
标题
Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug–Drug Interaction Studies
作者
关键词
-
出版物
CLINICAL PHARMACOKINETICS
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-02-13
DOI
10.1007/s40262-020-00867-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmacokinetics, Pharmacodynamics, and PKPD Modeling of Curcumin in Regulating Antioxidant and Epigenetic Gene Expression in Healthy Human Volunteers
- (2019) David Cheng et al. MOLECULAR PHARMACEUTICS
- A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Model of Dabigatran Etexilate, Dabigatran and Dabigatran Glucuronide in Healthy Adults and Renally Impaired Patients
- (2019) Daniel Moj et al. CLINICAL PHARMACOKINETICS
- Renal Excretion of Dabigatran: The Potential Role of Multidrug and Toxin Extrusion (MATE) Proteins
- (2019) Hong Shen et al. MOLECULAR PHARMACEUTICS
- TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL REGULATION OF DUODENAL P-GLYCOPROTEIN AND MRP2 IN HEALTHY HUMAN SUBJECTS AFTER CHRONIC TREATMENT WITH RIFAMPIN AND CARBAMAZEPINE
- (2019) Susanne Brueck et al. MOLECULAR PHARMACEUTICS
- Population Pharmacokinetics of Talazoparib in Patients With Advanced Cancer
- (2019) Yanke Yu et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Organic solute transporter OSTα/β is overexpressed in nonalcoholic steatohepatitis and modulated by drugs associated with liver injury
- (2018) Melina M. Malinen et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine
- (2018) Justin D. Lutz et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 1: Establishing Induction Relationships Using Ascending Dose Rifampin
- (2018) Justin D. Lutz et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms
- (2018) Cen Guo et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Understanding drug interactions with St John's wort (Hypericum perforatum L.): impact of hyperforin content
- (2018) Sigrun Chrubasik-Hausmann et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban
- (2017) Yuri Tsuruya et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Clinically Relevant Multidrug Transporters Are Regulated by microRNAs along the Human Intestine
- (2017) Henrike Bruckmueller et al. MOLECULAR PHARMACEUTICS
- Effects of the P-glycoprotein Inducer Carbamazepine on Fexofenadine Pharmacokinetics
- (2017) Satoshi Yamada et al. THERAPEUTIC DRUG MONITORING
- The Application of Physiologically Based Pharmacokinetic Modeling to Predict the Role of Drug Transporters: Scientific and Regulatory Perspectives
- (2016) Yuzhuo Pan et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Role of Hepatic Drug Transporters in Drug Development
- (2016) Houfu Liu et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites
- (2016) Mitesh Patel et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes
- (2016) Eric A. Benson et al. Frontiers in Pharmacology
- Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs
- (2016) D. Ravikumar Reddy et al. SpringerPlus
- BDDCS Predictions, Self-Correcting Aspects of BDDCS Assignments, BDDCS Assignment Corrections, and Classification for more than 175 Additional Drugs
- (2015) Chelsea M. Hosey et al. AAPS Journal
- Effect of quercetin on P-glycoprotein transport ability in Chinese healthy subjects
- (2013) S-Y Wang et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Taurolithocholate-induced MRP2 retrieval involves MARCKS phosphorylation by protein kinase Cϵ in HUH-NTCP Cells
- (2013) Christopher M. Schonhoff et al. HEPATOLOGY
- Dose-Dependent Targeted Suppression of P-glycoprotein Expression and Function in Caco-2 Cells
- (2013) Stephen D. Lee et al. MOLECULAR PHARMACEUTICS
- ATP-dependent transport of statins by human and rat MRP2/Mrp2
- (2013) Lucy C.J. Ellis et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin
- (2012) Sebastian Härtter et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP
- (2012) Hiroyuki Kusuhara et al. BRITISH JOURNAL OF PHARMACOLOGY
- Physiologically Based Pharmacokinetics Joined With In Vitro–In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology
- (2012) A Rostami-Hodjegan CLINICAL PHARMACOLOGY & THERAPEUTICS
- Role of CAR and PXR in xenobiotic sensing and metabolism
- (2012) Yue-Ming Wang et al. Expert Opinion on Drug Metabolism & Toxicology
- Effects of curcumin on the pharmacokinetics of talinolol in human withABCB1polymorphism
- (2012) X. He et al. XENOBIOTICA
- BDDCS Applied to Over 900 Drugs
- (2011) Leslie Z. Benet et al. AAPS Journal
- Digoxin Is Not a Substrate for Organic Anion-Transporting Polypeptide Transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but Is a Substrate for a Sodium-Dependent Transporter Expressed in HEK293 Cells
- (2011) M. E. Taub et al. DRUG METABOLISM AND DISPOSITION
- Quercetin and Rutin Reduced the Bioavailability of Cyclosporine from Neoral, an Immunosuppressant, through Activating P-Glycoprotein and CYP 3A4
- (2011) Chung-Ping Yu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Effect of genistein on the activities of cytochrome P450 3A and P-glycoprotein in Chinese healthy participants
- (2011) C.-Q. Xiao et al. XENOBIOTICA
- Rifampin's Acute Inhibitory and Chronic Inductive Drug Interactions: Experimental and Model-Based Approaches to Drug–Drug Interaction Trial Design
- (2010) M L Reitman et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Regulation of hepatic ABCC transporters by xenobiotics and in disease states
- (2010) Xinsheng Gu et al. DRUG METABOLISM REVIEWS
- Pharmacokinetics and Pharmacodynamics of the Direct Oral Thrombin Inhibitor Dabigatran in Healthy Elderly Subjects
- (2009) Joachim Stangier et al. CLINICAL PHARMACOKINETICS
- Endogenous Gene and Protein Expression of Drug-Transporting Proteins in Cell Lines Routinely Used in Drug Discovery Programs
- (2009) G. Ahlin et al. DRUG METABOLISM AND DISPOSITION
- Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers
- (2009) Kyoung-Ah Kim et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Species Difference in the Effect of Grapefruit Juice on Intestinal Absorption of Talinolol between Human and Rat
- (2009) Y. Shirasaka et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Integration of Preclinical and Clinical Data with Pharmacokinetic Modeling and Simulation to Evaluate Fexofenadine as a Probe for Hepatobiliary Transport Function
- (2009) Brandon Swift et al. PHARMACEUTICAL RESEARCH
- The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs
- (2009) Sarah Shugarts et al. PHARMACEUTICAL RESEARCH
- Pharmacokinetics of Phenytoin: Reminders and Discoveries
- (2009) Epilepsy Currents
- Quercetin pharmacokinetics in humans
- (2008) Young J. Moon et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer
- (2008) H. E. Meyer zu Schwabedissen et al. CANCER RESEARCH
- Effects of Spice Constituents on P-Glycoprotein-Mediated Transport and CYP3A4-Mediated Metabolism in Vitro
- (2008) W. Zhang et al. DRUG METABOLISM AND DISPOSITION
- Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
- (2008) X. Tian et al. DRUG METABOLISM AND DISPOSITION
- The Inhibition of Human Multidrug and Toxin Extrusion 1 Is Involved in the Drug-Drug Interaction Caused by Cimetidine
- (2008) S. Matsushima et al. DRUG METABOLISM AND DISPOSITION
- Coordinated induction of drug transporters and phase I and II metabolism in human liver slices
- (2008) P. Olinga et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Gauging the clinical significance of P‐glycoprotein‐mediated herb‐drug interactions: Comparative effects of St. John's wort, Echinacea, clarithromycin, and rifampin on digoxin pharmacokinetics
- (2008) Bill J. Gurley et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Involvement of Multiple Efflux Transporters in Hepatic Disposition of Fexofenadine
- (2008) S. Matsushima et al. MOLECULAR PHARMACOLOGY
- Phenytoin half-life and clearance during maintenance therapy in adults and elderly patients with epilepsy
- (2008) J. E. Ahn et al. NEUROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation