Single Cell Sequencing and Kidney Organoids Generated from Pluripotent Stem Cells

Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

(2019) Alexander N. Combes et al.   Genome Medicine

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

(2019) Mazène Hochane et al.   PLOS BIOLOGY

Tubuloids derived from human adult kidney and urine for personalized disease modeling

(2019) Frans Schutgens et al.   NATURE BIOTECHNOLOGY

How to rebuild the kidney: recent advances in kidney organoids

(2019) Mazharul Islam et al.   JOURNAL OF BIOCHEMISTRY

Reporter‐based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

(2019) Sara E Howden et al.   EMBO REPORTS

Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial

(2019) Hiddo J L Heerspink et al.   LANCET

A comparison of single-cell trajectory inference methods

(2019) Wouter Saelens et al.   NATURE BIOTECHNOLOGY

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

(2019) Vlado Perkovic et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms

(2018) Thomas A. Forbes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

(2018) Stefan M. Czerniecki et al.   Cell Stem Cell

Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning

(2018) Nils O. Lindström et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney

(2018) Nils O. Lindström et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis

(2018) Nils O. Lindström et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

(2018) Krijn K. Dijkstra et al.   CELL

Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes

(2018) Shunsuke Tanigawa et al.   Stem Cell Reports

Organoid Modeling of the Tumor Immune Microenvironment

(2018) James T. Neal et al.   CELL

Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

(2018) Haojia Wu et al.   Cell Stem Cell

Single-cell mapping of lineage and identity in direct reprogramming

(2018) Brent A. Biddy et al.   NATURE

Evaluation of variability in human kidney organoids

(2018) Belinda Phipson et al.   NATURE METHODS

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

(2018) Lorna J. Hale et al.   Nature Communications

The promise of single-cell RNA sequencing for kidney disease investigation

(2017) Haojia Wu et al.   KIDNEY INTERNATIONAL

Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease

(2017) Nelly M. Cruz et al.   NATURE MATERIALS

Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development

(2017) Yong Kyun Kim et al.   STEM CELLS

The Human Cell Atlas

(2017) Aviv Regev et al.   eLife

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

(2016) Atray Dixit et al.   CELL

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

(2016) Britt Adamson et al.   CELL

Adriamycin susceptibility among C57BL/6 substrains

(2016) Ehtesham Arif et al.   KIDNEY INTERNATIONAL

Bridging Translation by Improving Preclinical Study Design in AKI

(2015) M. de Caestecker et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

(2015) Ryuji Morizane et al.   NATURE BIOTECHNOLOGY

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

(2015) Benjamin S. Freedman et al.   Nature Communications

Comparison of the transcriptional landscapes between human and mouse tissues

(2014) Shin Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lineage-tracing methods and the kidney

(2013) Benjamin D. Humphreys et al.   KIDNEY INTERNATIONAL

Mature cells can be rejuvenated

(2012) Janet Rossant et al.   NATURE

Mammalian Kidney Development: Principles, Progress, and Projections

(2012) M. H. Little et al.   Cold Spring Harbor Perspectives in Biology

C57BL/6 and 129/Sv mice: genetic difference to renal ischemia-reperfusion

(2011) Xia Lu et al.   JOURNAL OF NEPHROLOGY

Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding

(2010) D. Schmidt et al.   SCIENCE