期刊
CLINICAL INFECTIOUS DISEASES
卷 71, 期 6, 页码 1554-1557出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciz1245
关键词
broad-range universal PCR; DNA sequencing; molecular diagnostics; pathogen identification
资金
- National Institute of Allergy and Infectious Diseases [K23AI134327]
We assessed the real-world utility of universal broad-range polymerase chain reaction sequencing for pathogen detection. Among 1062 clinical samples, 107/1062 (10.1%) had a clinically significant, positive result, with substantial variation by specimen type. Clinical management was changed in 44/1062 (4.1%). These data can help maximize utility of this emerging diagnostic.
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