Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart

Reconceptualization of the Molecular Mechanism by Which Sodium-Glucose Cotransporter 2 Inhibitors Reduce the Risk of Heart Failure Events

(2019) Milton Packer   CIRCULATION

Enhancing fatty acid utilization ameliorates mitochondrial fragmentation and cardiac dysfunction via rebalancing optic atrophy 1 processing in the failing heart

(2018) Yongzheng Guo et al.   CARDIOVASCULAR RESEARCH

saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription

(2016) Victoria Portnoy et al.   CELL RESEARCH

MicroRNA-21 Lowers Blood Pressure in Spontaneous Hypertensive Rats by Upregulating Mitochondrial TranslationClinical Perspective

(2016) Huaping Li et al.   CIRCULATION

Viral Vector-Based Targeting of miR-21 in Cardiac Nonmyocyte Cells Reduces Pathologic Remodeling of the Heart

(2016) Deepak Ramanujam et al.   MOLECULAR THERAPY

Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells

(2015) Dianke Yu et al.   BIOCHEMICAL PHARMACOLOGY

MicroRNA profiling unveils hyperglycaemic memory in the diabetic heart

(2015) Sarah Costantino et al.   EUROPEAN HEART JOURNAL

MiR-320a contributes to atherogenesis by augmenting multiple risk factors and down-regulating SRF

(2015) Chen Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Heart failure in diabetes: effects of anti-hyperglycaemic drug therapy

(2015) Richard E Gilbert et al.   LANCET

Regulation of AMPK Activation by CD36 Links Fatty Acid Uptake to β-Oxidation

(2014) Dmitri Samovski et al.   DIABETES

MicroRNAs as non-invasive biomarkers of heart transplant rejection

(2014) J.-P. Duong Van Huyen et al.   EUROPEAN HEART JOURNAL

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

Myocardial Loss of IRS1 and IRS2 Causes Heart Failure and Is Controlled by p38  MAPK During Insulin Resistance

(2013) Y. Qi et al.   DIABETES

A comprehensive characterization of the nuclear microRNA repertoire of post-mitotic neurons

(2013) Sharof A. Khudayberdiev et al.   Frontiers in Molecular Neuroscience

Short-Term Hyperinsulinemia and Hyperglycemia Increase Myocardial Lipid Content in Normal Subjects

(2012) Yvonne Winhofer et al.   DIABETES

Protective Effects of Acyl-coA Thioesterase 1 on Diabetic Heart via PPARα/PGC1α Signaling

(2012) Shenglan Yang et al.   PLoS One

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

(2012) Ahmet Ucar et al.   Nature Communications

RNAi-independent role for Argonaute2 in CTCF/CP190 chromatin insulator function

(2011) N. Moshkovich et al.   GENES & DEVELOPMENT

Diabetic cardiomyopathy, causes and effects

(2010) Sihem Boudina et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells

(2009) Takeshi Haraguchi et al.   NUCLEIC ACIDS RESEARCH

Myocardial Steatosis Is an Independent Predictor of Diastolic Dysfunction in Type 2 Diabetes Mellitus

(2008) Luuk J. Rijzewijk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Antisense transcripts are targets for activating small RNAs

(2008) Jacob C Schwartz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY