Article
Environmental Sciences
Kaihang Mi, Xi Chen, Kaiyuan Lu, Yujie Zhu, Meng Zhang, Hui Yang, Wenzhi Wei, Yingying Zhang
Summary: The study showed that BPA exposure significantly increased hepatic lipid deposition in male rare minnow, with an increase in triglyceride level and a decrease in diglyceride level. The expression of lipid metabolism related genes indicated that BPA up-regulates TG synthesis related genes expression and down-regulates TG degradation genes expression, disrupting TG transport related genes as well. Overall, the study enriches the understanding of how environmental endocrine disruptors like BPA affect lipid accumulation in fish.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Long Zhu, Yan Liu, Xue Xue, Cong Yuan, Zaizhao Wang
Summary: The research found that parental exposure to BPA negatively affects offspring ovarian development by reducing the number of mature oocytes and affecting the expression of steroidogenic genes. However, the adverse effects of parental BPA exposure on offspring are reversible.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Marine & Freshwater Biology
Long Zhu, Lihong Wang, Xiaoteng Fan, Chenglong Dong, Gaoxue Wang, Zaizhao Wang
Summary: Chronic exposure to BPA in fish can impair male reproductive capacity, leading to decreased fertilization ability and motility of sperm. BPA induces oxidative stress, inflammatory response, and DNA/histone methylation, affecting the normal function of the reproductive system.
AQUATIC TOXICOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Zhu Zhu, Jian Ju, Meng Zhang, Hui Yang, Wenzhi Wei, Yingying Zhang
Summary: The study found that BPA can disrupt hepatic ApoA1 expression by regulating Esrrg recruitment and DNA methylation, ultimately increasing ApoA1 protein levels. This leads to elevated hepatic ApoA1 levels, improved HDL-C levels, enhanced RCT, and disturbed cholesterol levels.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Environmental Sciences
Jianlu Zhang, Zhu Zhu, Jiqin Huang, Hui Yang, Qijun Wang, Yingying Zhang
Summary: This study found that BPA exposure can disrupt lipid metabolism in the testes of rare minnows, leading to abnormalities in sperm morphology and function.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Environmental Sciences
Junxia Shi, Chenyu Liu, Mingyue Chen, Jinhui Yan, Chonggang Wang, Zhenghong Zuo, Chengyong He
Summary: The study demonstrates that exposure to environmentally relevant levels of BPA can disrupt steroid hormone synthesis in human ovarian granulosa cells, leading to decreased gene expression in hormone synthesis and inhibition of the FSHR/GS/AC signaling pathway.
ENVIRONMENTAL TOXICOLOGY
(2021)
Article
Environmental Sciences
Yingying Zhang, Zhu Zhu, Qiao Liu, Meng Zhang, Hui Yang, Wenzhi Wei
Summary: Studies have shown that BPA can cause lipid metabolism disorder, with few focusing on its effect on lipid transport. This study found that BPA exposure affected the expression of ApoE in rare minnows, potentially disrupting fish lipid metabolism. Additionally, the recruitment of Esrrg and methylation status of CpG sites near ApoE were identified as potential mechanisms for these effects.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Biochemistry & Molecular Biology
Juan Chen, Hang Chen, Yingyi Wu, Juanzhu Meng, Li Jin
Summary: This study evaluated the toxicity of CdSe/ZnS quantum dots on the skeletal development of the rare minnows' next generation using rare minnows as model animals. The results showed that maternal exposure to quantum dots led to decreased body length, overall calcium content, and increased deformity and mortality rates in the F1 embryos. The quantum dots also affected the craniofacial bone and inhibited the expression of several genes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Microbiology
Jiangwen Cheng, Hong Zou, Ming Li, Jianwei Wang, Guitang Wang, Wenxiang Li
Summary: This study investigated dactylogyrid infection in the rare minnow Gobiocypris rarus and determined the species of Dactylogyrus collected from this fish. Histopathology analysis showed that heavy dactylogyrid infection caused necrosis of gill filaments and inflammatory responses. The morphological characteristics and 18S-ITS1 rDNA sequence provided basic data for identification of this parasite species.
Article
Marine & Freshwater Biology
Jing Yang, Yumeng Chen, Haiyang Luan, Jingwen Li, Wei Liu
Summary: The persistent adverse effects of developmental exposure to Cl-PFESA on fish's gonadal development are of significant concern. After 4 weeks of exposure, the body weight and length of juvenile fish increased, while gene expression of gnrh3, lh beta, and cyp19a decreased and ar and er alpha were upregulated. After 12 weeks of depuration, the gonadosomatic indices decreased in female fish, with increasing numbers of degenerating oocytes and perinucleolar oocytes, and decreasing numbers of mature vitellogenic oocytes. The exposed male fish showed an enlarged interstitial space of the testis, and gene expression levels of gnrh3, lh beta, ar, er alpha, and vtg were upregulated in the adult fish.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Miaoling Lin, Rui Hua, Jing Ma, Yao Zhou, Pei Li, Xiya Xu, Zhiqiang Yu, Song Quan
Summary: This study demonstrated that BPA exposure could significantly decrease human ovarian functions and lead to abnormal folliculogenesis by activating autophagy in GCs through the AMPK/mTOR/ULK1 pathway.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Fisheries
Yuefeng Lv, Yingying Wang, Qing Wang, Yingying Li, Jiyuan Yin, Guang Yang, Cunbin Shi, Bo Li, Yahui Wang, Sven M. Bergmann, Weiwei Zeng
Summary: The GrB cell line, established from brain tissues of the rare minnow, is suitable for transfection studies and has shown susceptibility to Tilapia Lake Virus infection. The cells require specific temperature and medium conditions for optimal growth, making them a valuable model for fish virology and immunology research.
AQUACULTURE RESEARCH
(2022)
Article
Physiology
Liangxia Su, Huanhuan Li, Ning Qiu, Yinrui Wu, Bing Hu, Rui Wang, Jun Liu, Jianwei Wang
Summary: Cadmium exposure at low concentrations can affect the reproductive activity of rare minnows, reducing the success rate of pair spawning and prolonging the time for first spawning. However, it increases the mean egg production. Cadmium exposure also affects the gonads of rare minnows, but has minimal impact on their condition factor and gonadosomatic index. The reproductive risk of low-dose cadmium exposure to fish species remains a cause for concern.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Multidisciplinary Sciences
Xudong Hu, Haorong Li, Yusheng Lin, Zhongkai Wang, Haohao Feng, Man Zhou, Lixia Shi, Hong Cao, Yandong Ren
Summary: Gobiocypris rarus is sensitive to environmental pollution, and genetic deciphering of its unique immune system can enhance our understanding of its adaptive strategies. The de novo genome of Gobiocypris rarus has been obtained, and its sex determination mechanism is ZZ/ZW. Analysis of specific mutation genes and gene expression levels reveals the sensitivity of Gobiocypris rarus to environmental stimuli. Additionally, Gobiocypris rarus shows potential as an emerging experimental model for genetic manipulation.
Article
Genetics & Heredity
Qingfeng Liu, Xuanyi Zhang, Junmei Liu, Fanglei Liu, Fangming Shi, Qinbo Qin, Min Tao, Chenchen Tang, Shaojun Liu
Summary: This study obtained an allodiploid fish BR with 49 chromosomes through distant hybridization, which showed significantly different morphological traits and growth rates compared to its parent species. The 5S rDNA of BR inherited specific bands from its parents and exhibited obvious recombination and heredity.
FRONTIERS IN GENETICS
(2021)
Article
Marine & Freshwater Biology
Julin Yuan, Zhimin Gu, Yao Zheng, Yingying Zhang, Jiancao Gao, Shu Chen, Zaizhao Wang
AQUATIC TOXICOLOGY
(2016)
Article
Environmental Sciences
Yingying Zhang, Cong Yuan, Jiancao Gao, Yan Liu, Zaizhao Wang
Article
Environmental Sciences
Yingying Zhang, Shiyu Tao, Cong Yuan, Yan Liu, Zaizhao Wang
Article
Environmental Sciences
Yingying Zhang, Yongjing Guan, Ting Zhang, Cong Yuan, Yan Liu, Zaizhao Wang
Article
Environmental Sciences
Jia Jia, Yongjing Guan, Mengqian Cheng, Hong Chen, Jiafa He, Song Wang, Zaizhao Wang
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Environmental Sciences
Song Wang, Zeliang Zhu, Jiafa He, Xiaoya Yue, Jianxiong Pan, Zaizhao Wang
ENVIRONMENTAL POLLUTION
(2018)
Article
Endocrinology & Metabolism
Ting Zhang, Yongjing Guan, Song Wang, Lihong Wang, Mengqian Cheng, Cong Yuan, Yan Liu, Zaizhao Wang
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2018)
Article
Marine & Freshwater Biology
Yongjing Guan, Ting Zhang, Jiafa He, Jia Jia, Long Zhu, Zaizhao Wang
AQUATIC TOXICOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Lang Wu, Qiuguo Yu, Guo Zhang, Feili Wu, Yingying Zhang, Cong Yuan, Ting Zhang, Zaizhao Wang
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2019)
Article
Environmental Sciences
Xiaoteng Fan, Tingting Hou, Shuai Zhang, Yongjing Guan, Jia Jia, Zaizhao Wang
Article
Environmental Sciences
Xiaoteng Fan, Tingting Hou, Tianzi Sun, Long Zhu, Shuai Zhang, Kui Tang, Zaizhao Wang
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Environmental Sciences
Xiaoteng Fan, Tingting Hou, Yongjing Guan, Xiangju Li, Shuai Zhang, Zaizhao Wang
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Ecology
Lihong Wang, Long Zhu, Kui Tang, Mengyu Liu, Xue Xue, Gaoxue Wang, Zaizhao Wang
Summary: The study analyzed the genetic structure of Sharpbelly Hemiculter leucisculus across different environments by using genetic and morphological data, revealing significant differences in body size and shape among populations primarily influenced by selective pressures along climate gradients. Southern populations had deeper-bodied fish, while individuals in the north were more slender, and inland individuals more streamlined compared to coastal individuals with deeper bodies.
ECOLOGY AND EVOLUTION
(2021)
Article
Environmental Sciences
Cong Yuan, Yingying Zhang, Yan Liu, Song Wang, Zaizhao Wang