A Practical Method for Continuous Production of sp3‐Rich Compounds from (Hetero)Aryl Halides and Redox‐Active Esters
出版年份 2019 全文链接
标题
A Practical Method for Continuous Production of sp3‐Rich Compounds from (Hetero)Aryl Halides and Redox‐Active Esters
作者
关键词
-
出版物
CHEMISTRY-A EUROPEAN JOURNAL
Volume 26, Issue 1, Pages 186-191
出版商
Wiley
发表日期
2019-11-06
DOI
10.1002/chem.201905048
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Quaternary Centers via Ni-Catalyzed Cross-Coupling of Tertiary Carboxylic Acids and Aryl Zinc Reagents
- (2019) Phil S. Baran et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ni-catalyzed Reductive Liebeskind-Srogl Alkylation of Heterocycles
- (2019) Yuanhong Ma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ni-catalyzed Reductive Deaminative Arylation at sp3 Carbon Centers
- (2019) Raul Martin-Montero et al. ORGANIC LETTERS
- Deaminative Reductive Cross-Electrophile Couplings of Alkylpyridinium Salts and Aryl Bromides
- (2019) Jennie Liao et al. ORGANIC LETTERS
- Selective Syntheses of Z-Alkenes via Photocatalyzed Decarboxylative Coupling of N-Hydroxyphthalimide Esters with Terminal Arylalkynes
- (2019) Guo-Li Dai et al. ORGANIC LETTERS
- One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp2–Sp3 Cross-Coupling
- (2019) Takaoki Koyanagi et al. ORGANIC LETTERS
- Harnessing Alkylpyridinium Salts as Electrophiles in Deaminative Alkyl–Alkyl Cross-Couplings
- (2019) Shane Plunkett et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines
- (2019) Shengyang Ni et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ketones from Nickel-Catalyzed Decarboxylative, Non-Symmetric Cross-Electrophile Coupling of Carboxylic Acid Esters
- (2019) Jiang Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Are We Opening the Door to a New Era of Medicinal Chemistry or Being Collapsed to a Chemical Singularity?
- (2019) Yan A. Ivanenkov et al. JOURNAL OF MEDICINAL CHEMISTRY
- Desulfonylative Arylation of Redox-Active Alkyl Sulfones with Aryl Bromides
- (2019) Jonathan M. E. Hughes et al. ORGANIC LETTERS
- Metal-Reductant-Free Electrochemical Nickel-Catalyzed Couplings of Aryl and Alkyl Bromides in Acetonitrile
- (2019) Robert J. Perkins et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Ni-Catalyzed Carbon–Carbon Bond-Forming Reductive Amination
- (2018) Christoph Heinz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Organic synthesis provides opportunities to transform drug discovery
- (2018) David C. Blakemore et al. Nature Chemistry
- On-demand synthesis of organozinc halides under continuous flow conditions
- (2018) Mateo Berton et al. Nature Protocols
- Impact of a five-dimensional framework on R&D productivity at AstraZeneca
- (2018) Paul Morgan et al. NATURE REVIEWS DRUG DISCOVERY
- Ni-Catalyzed Electrochemical Decarboxylative C–C Couplings in Batch and Continuous Flow
- (2018) Hui Li et al. ORGANIC LETTERS
- Decarboxylative Negishi Coupling of Redox-Active Aliphatic Esters by Cobalt Catalysis
- (2018) Xu-Ge Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct arylation of strong aliphatic C–H bonds
- (2018) Ian B. Perry et al. NATURE
- Ni-Catalyzed Reductive Coupling of Electron-Rich Aryl Iodides with Tertiary Alkyl Halides
- (2018) Xuan Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Zn-Mediated Fragmentation of Tertiary Alkyl Oxalates Enabling Formation of Alkylated and Arylated Quaternary Carbon Centers
- (2018) Yang Ye et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Generation and Cross-Coupling of Organozinc Reagents in Flow
- (2018) Ananda Herath et al. ORGANIC LETTERS
- Cross-Coupling and Related Reactions: Connecting Past Success to the Development of New Reactions for the Future
- (2018) Louis-Charles Campeau et al. ORGANOMETALLICS
- Nickel-Catalyzed Enantioselective Reductive Cross-Coupling of Styrenyl Aziridines
- (2017) Brian P. Woods et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Decarboxylative alkenylation
- (2017) Jacob T. Edwards et al. NATURE
- Decarboxylative Borylation of Aliphatic Esters under Visible-Light Photoredox Conditions
- (2017) Dawei Hu et al. ORGANIC LETTERS
- Recent Advances in Nickel Catalysis Enabled by Stoichiometric Metallic Reducing Agents
- (2017) Edward Richmond et al. SYNTHESIS-STUTTGART
- Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteres
- (2016) Chad M. Kormos et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Improving Drug Design: An Update on Recent Applications of Efficiency Metrics, Strategies for Replacing Problematic Elements, and Compounds in Nontraditional Drug Space
- (2016) Nicholas A. Meanwell CHEMICAL RESEARCH IN TOXICOLOGY
- Chemoinformatic expedition of the chemical space of fungal products
- (2016) Mariana González-Medina et al. Future Medicinal Chemistry
- Practical Ni-Catalyzed Aryl–Alkyl Cross-Coupling of Secondary Redox-Active Esters
- (2016) Josep Cornella et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Decarboxylative Cross-Electrophile Coupling of N-Hydroxyphthalimide Esters with Aryl Iodides
- (2016) Kierra M. M. Huihui et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Metallaphotoredox-catalysed sp3–sp3 cross-coupling of carboxylic acids with alkyl halides
- (2016) Craig P. Johnston et al. NATURE
- A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents
- (2016) T. Qin et al. SCIENCE
- Methods and Mechanisms for Cross-Electrophile Coupling of Csp2 Halides with Alkyl Electrophiles
- (2015) Daniel J. Weix ACCOUNTS OF CHEMICAL RESEARCH
- Machine-Assisted Organic Synthesis
- (2015) Steven V. Ley et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds
- (2015) Jian-Siang Poh et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Explosion behaviour of metallic nano powders
- (2015) Arne Krietsch et al. JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES
- Enantioselective Cross-Coupling of meso-Epoxides with Aryl Halides
- (2015) Yang Zhao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Generation of Reactive Ketenes under Flow Conditions through Zinc-Mediated Dehalogenation
- (2015) Steven Ley et al. SYNLETT
- Cobalt co-catalysis for cross-electrophile coupling: diarylmethanes from benzyl mesylates and aryl halides
- (2015) Laura K. G. Ackerman et al. Chemical Science
- Flow chemistry as a discovery tool to access sp2–sp3 cross-coupling reactions via diazo compounds
- (2015) Duc N. Tran et al. Chemical Science
- Nickel-catalyzed reductive coupling of alkyl halides with other electrophiles: concept and mechanistic considerations
- (2015) Jun Gu et al. Organic Chemistry Frontiers
- Continuous Synthesis of Organozinc Halides Coupled to Negishi Reactions
- (2014) Nerea Alonso et al. ADVANCED SYNTHESIS & CATALYSIS
- A Systems Approach towards an Intelligent and Self-Controlling Platform for Integrated Continuous Reaction Sequences
- (2014) Richard J. Ingham et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Merging photoredox with nickel catalysis: Coupling of -carboxyl sp3-carbons with aryl halides
- (2014) Z. Zuo et al. SCIENCE
- Nickel-Catalyzed Regiodivergent Opening of Epoxides with Aryl Halides: Co-Catalysis Controls Regioselectivity
- (2013) Yang Zhao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Escape from Flatland 2: complexity and promiscuity
- (2012) Frank Lovering MedChemComm
- Nickel-Catalyzed Reductive Cross-Coupling of Aryl Halides with Alkyl Halides
- (2010) Daniel A. Everson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles
- (2010) P. A. Clemons et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
- (2009) Frank Lovering et al. JOURNAL OF MEDICINAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started