Article
Biotechnology & Applied Microbiology
Satyendra Jyoti, Satyendra Singh, Sumistha Das, Shaili Srivastava
Summary: A comparative study was conducted to remove hexavalent chromium from wastewater using synthesized nanoparticles such as chitin, chitosan, zinc oxide, and ZnO-chitosan composite. The results showed that the ZnO-chitosan nanobiocomposite had the highest uptake capacity for chromium (VI). The optimal conditions for adsorption were found to be a concentration of 20 ppm, a dosage of 0.5 g/l, pH 3, and a time of 60 min.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2023)
Article
Chemistry, Physical
Mazdak Hashempour, Mariangela Longhi, Luigi Brambilla, Antonello Vicenzo
Summary: This study reports on the formation of reduced graphene oxide/chitosan hybrids via L -ascorbic acid reduction and provides a detailed characterization of the hybrids. The study shows that the hybrids exhibit improved electrochemical performance and packing behavior compared to pure reduced graphene oxide.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Physical
Sabra Rostami, Fatih Puza, Meltem Ucak, Erdogan Ozgur, Ozgur Gul, Utku Kursat Ercan, Bora Garipcan
Summary: The study demonstrates that sharkskin topography possesses excellent antibacterial activity, while sharkskin mimicked membranes coated with graphene oxide exhibit superior cytocompatibility, indicating significant potential for diverse biomedical applications.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Applied
Ming-Hong Lin, Yan-Hsiung Wang, Cheng-Hsien Kuo, Shih-Fu Ou, Pin-Zhen Huang, Tzu-Yu Song, Yi-Cheng Chen, Shyi-Tien Chen, Chien-Hui Wu, Yi-Huang Hsueh, Fang-Yu Fan
Summary: The biocomposite coating consisting of chitosan and ZnO shows enhanced antibacterial properties and bioactivity, effectively inhibiting bacterial adhesion and biofilm formation. The release of Zn2+ ions is attributed to the improved properties, including increased antibacterial activity and corrosion resistance. Additionally, the coating exhibits good cytocompatibility in MG-63 cells compared to pure Ti.
CARBOHYDRATE POLYMERS
(2021)
Article
Infectious Diseases
Lemiha Yildizbakan, Neelam Iqbal, Payal Ganguly, Eric Kumi-Barimah, Thuy Do, Elena Jones, Peter V. V. Giannoudis, Animesh Jha
Summary: To address bone damage-related complications, highly porous chitosan scaffolds were engineered with iron-doped dicalcium phosphate dihydrate minerals and different concentrations of cerium oxide nanoparticles. The scaffolds exhibited altered physicochemical properties and enhanced antibacterial characteristics with increasing cerium oxide concentrations. They showed promising potential for tissue regeneration, mitigating infection risks, and inhibiting bacterial growth, while exhibiting negligible cytotoxic effects.
Article
Biochemistry & Molecular Biology
Anbazhagan Sathiyaseelan, Kandasamy Saravanakumar, Xin Zhang, Kumar Vishven Naveen, Myeong-Hyeon Wang
Summary: Drug-resistant microorganisms can be overcome by using combinational drug delivery systems based on biopolymer chitosan (CS) and metal nanoparticles. Therefore, PEGylated zinc oxide nanoparticles (P-ZnO NPs) decorated chitosan-based nanoparticles (CS NPs) were prepared to deliver ampicillin (AMP) for improved antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Biomedical
Anandhavelu Sanmugam, S. Abbishek, S. Logesh Kumar, Ananda Babu Sairam, Vishnu Vardhan Palem, Raju Suresh Kumar, Abdulrahman I. Almansour, Natarajan Arumugam, Dhanasekaran Vikraman
Summary: The unique characteristics of chitosan, reduced graphene oxide (rGO), and cerium oxide (CeO2) based hybrid bionano-composites make them potential biomaterials for drug delivery and antimicrobial applications. The addition of biopolymers to rGO and CeO2 based nanocomposites has shown excellent performance in various applications such as biosensors, wound dressings, electrodes, microfluidic chips, drug delivery systems, and energy storage. The physiochemical characterization of the hybrid bionano-composites revealed their crystalline structure, interaction between chitosan and rGO-CeO2, and better thermal stability up to 550 degrees C. Additionally, the nanocomposites exhibited antibacterial properties and superior cell adhesion.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Nguyen Minh Dat, Le Minh Huong, Che Quang Cong, Nguyen Duy Hai, Nguyen Thanh Hoai Nam, Doan Ba Thinh, Huynh Khanh Duy, Tong Thanh Danh, Pham Hoang Huy Phuoc Loi, Mai Thanh Phong, Nguyen Huu Hieu
Summary: In this study, selenium microparticles were synthesized using plant leaf extract and decorated onto graphene oxide to create a composite material. The composite exhibited strong antibacterial properties and good thermal and mechanical characteristics.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Paper & Wood
O. L. Evdokimova, M. E. Belousova, A. V. Evdokimova, T. V. Kusova, A. E. Baranchikov, K. S. Antonets, A. A. Nizhnikov, A. V. Agafonov
Summary: A new water-based approach was developed for producing antibacterial nanocellulose/Cu2O hybrid films, showing good antibacterial activity against bacteria strains. The Cu2O NPs exhibit different sensitivities towards different bacterial strains, making them a potential application in the treatment of wounds and skin infections.
Review
Environmental Sciences
Thiruchelvi Pulingam, Kwai Lin Thong, Jimmy Nelson Appaturi, Chin Wei Lai, Bey Fen Leo
Summary: The recent advances in nanotechnology have led to increased use of nanomaterials in various fields. Graphene oxide (GO) shows promise as an antibacterial material, but further research is needed to fully understand its mechanism of action.
Article
Chemistry, Analytical
Yueshui Lyu, Yingying Shi, Sen Zhu, Yuan Jia, Chunfeng Tong, Shixiong Liu, Bo Sun, Jingxiang Zhang
Summary: In this study, an antibacterial device was developed by combining silver nanoparticles with reduced graphene oxide, demonstrating excellent bacterial removal capacity and potential applications in sewage treatment and sensor protection.
Article
Spectroscopy
Eman I. Khalaf, Nagi M. El-Shafai, Ali M. Nassar, Essam E. Assem, Ibrahim S. Yahia, Ibrahim M. El-Mehasseb
Summary: This study developed a novel nano-combination membrane by integrating terbium oxide nanoparticles and nickel oxide nanoparticles onto the surface of graphene oxide. The fabricated membrane showed efficient removal of organic pollutants and photocatalytic activity. Furthermore, low cytotoxicity was observed on cancer cells treated with the membrane.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Materials Science, Multidisciplinary
D. Sanchez-Campos, M. G. Pena-Juarez, D. Salado-Leza, D. Mendoza-Anaya, V. Rodriguez-Lugo, J. A. Gonzalez-Calderon, E. Perez
Summary: A composite material containing hydroxyapatite, graphene oxide and silver nanoparticles was synthesized using a microwave-assisted hydrothermal method. The addition of dietary quercetin was utilized for the formation and deposition of silver nanoparticles. The composite exhibited cytotoxicity in human keratinocytes dependent on the presence of graphene oxide, while samples containing hydroxyapatite showed superior cytocompatibility. The ternary system displayed increased inhibition zone against S. aureus and E. coli compared to silver nanoparticles alone, making it a potential bactericidal material for tissue replacement and surface coating.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Materials Science, Textiles
Lihuan Zhao, Siyu Zhang, Yuwen Wang, Jun Li, Yanyan Li, Yujie Yang, Silu Liu
Summary: An antibacterial compression garment fabric was prepared using a graphene oxide/chitosan composite as an antibacterial agent. The durability and physical properties of the fabric were improved by modifying it with silane coupling agent gamma-(methacryloxy) propyl trimethoxysilane. The fabric showed antibacterial activity against both gram-negative and gram-positive bacteria, with high bacteriostatic rates. While the comfort of the fabric was slightly affected, it showed no potential cytotoxicity or skin irritation. The antibacterial fabric could effectively reduce bacterial infection rates in patients wearing compression garments, alleviating patient suffering.
FIBERS AND POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Antonysamy Jeyaseelan, Norah Salem Alsaiari, Khadijah Mohammedsaleh M. Katubi, Mu Naushad, Natrayasamy Viswanathan
Summary: The AGO@CS composite beads with promising defluoridation capacity were efficiently prepared and studied, showing a possible mechanism of electrostatic attraction for fluoride removal. They are reusable and applicable in field circumstances.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Food Science & Technology
Elham Assadpour, Asli Can Karaca, Mahdis Fasamanesh, Sahar Akhavan Mahdavi, Mahya Shariat-Alavi, Jianguo Feng, Mohammad Saeed Kharazmi, Abdur Rehman, Seid Mahdi Jafari
Summary: There is an urgent need for sustainable and eco-friendly pesticide formulations due to the adverse effects of common synthetic pesticides on human health and the environment. Essential oils (EOs) from medicinal plants have shown efficacy against pests and pathogenic fungi, making them suitable as sustainable and environmentally friendly biopesticides. However, challenges such as reduced stability and efficiency under environmental conditions need to be addressed for widespread commercial use of EO-based biopesticides.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Behavioral Sciences
Kirti Agrawal, Pratik Chakraborty, Saikat Dewanjee, Saniya Arfin, Sabya Sachi Das, Abhijit Dey, Mahmoud Moustafa, Prabhu Chandra Mishra, Seid Mahdi Jafari, Niraj Kumar Jha, Saurabh Kumar Jha, Dhruv Kumar
Summary: Quercetin, a naturally occurring bioactive flavonoid, has shown therapeutic potential in preclinical tests against neurological disorders. Its protective role against oxidative stress and neuroinflammation make it a possible choice for treatment. However, the specific molecular targets of quercetin and its derivatives, such as nuclear receptors and proinflammatory mediators, are yet to be explored.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Engineering, Biomedical
Xin Li, Seid Mahdi Jafari, Feibai Zhou, Hui Hong, Xin Jia, Xiaohong Mei, Guohua Hou, Yu Yuan, Bin Liu, Shanan Chen, Yifu Gong, Huiling Yan, Ruxin Chang, Jiayin Zhang, Fazheng Ren, Yuan Li
Summary: Nanocarriers with different physical properties were prepared to study their impact on endocytosis mechanisms, internalization pathways, transport efficiency, and bioavailability. Nanospheres were mainly internalized via clathrin-mediated endocytosis, while macropinocytosis was the primary pathway for nanotubes. Nanotubes showed the ability to overcome multi-drug resistance and open intercellular tight-junctions for transport into blood circulation. The bioavailability of hydrophobic bioactive mangiferin was improved by nanocarriers, with the highest bioavailability observed for cross-linked short nanotubes. Furthermore, Mgf-loaded CSNT showed excellent therapeutic efficiency for diabetes intervention.
Review
Food Science & Technology
Shima Jafarzadeh, Mehrdad Forough, Vahid Javan Kouzegaran, Masoumeh Zargar, Farhad Garavand, Maryam Azizi-Lalabadi, Mehdi Abdollahi, Seid Mahdi Jafari
Summary: This review article discusses a new generation of biodegradable active and smart packaging based on porous nanomaterials (PNMs), which maintains food quality and freshness while meeting biodegradability requirements. PNMs have gained significant attention in the field of food packaging due to their large surface area, peculiar structures, functional flexibility, and thermal stability. The review presents recent literature on the incorporation of PNMs into renewable materials for the development of advanced, environmentally friendly packaging technology. It also explores the effects of PNMs on the functionality of biopolymeric films and how smart packaging loaded with PNMs can improve food shelf life and reduce waste.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Review
Food Science & Technology
Fatemeh Rafieian, Reza Amani, Atefe Rezaei, Asli Can Karaca, Seid Mahdi Jafari
Summary: Fennel, a hardy and perennial herb, has become widespread worldwide and is used as a medicinal and culinary herb. It has shown various pharmacological activities including antibacterial, antifungal, antiviral, antioxidant, anti-inflammatory, antimutagenic, antinociceptive, hepatoprotective, bronchodilatory, and memory-enhancing activities. It has also been effective in infantile colic, dysmenorrhea, polycystic ovarian syndrome, and milk production. This review aims to summarize recent research on the chemical composition, functional properties, and toxicology of fennel, and identify gaps in the literature for future research.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Tolulope Joshua Ashaolu, Mohammad Zarei, Himani Agrawal, Mohammad Saeed Kharazmi, Seid Mahdi Jafari
Summary: Plant protein components contribute positively to human well-being as they modulate immune status. This study aimed to search for relevant information on plant-based immunomodulatory peptides over the past three decades. The core of immunomodulation and types of immunomodulatory agents, as well as the production and mechanisms of plant-based immunomodulatory peptides, were discussed. Applications and challenges associated with these peptides were also addressed.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Nabila Belyagoubi-Benhammou, Larbi Belyagoubi, Bouchra Loukidi, Mudasir A. Mir, Elham Assadpour, Mohammed Boudghene-Stambouli, Mohammad Saeed Kharazmi, Seid Mahdi Jafari
Summary: Saffron, a plant of the Iridaceae family, has been used in traditional medicine, culinary preparations, and cosmetics. The saffron tepals, which contain bioactive compounds, are the main by-product of saffron processing. This review aims to explore the characteristics, composition, biological activities, and uses of saffron flower tepals in cosmetology and perfumery.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Amir Akbarmehr, Seyed Hadi Peighambardoust, Maral Soltanzadeh, Seid Mahdi Jafari, Khashayar Sarabandi
Summary: The effects of hydrolyzed whey protein concentrate (WPC) and its combination with polysaccharides as wall material in spray-drying microencapsulation of Yerba mate extract (YME) were investigated. The results showed that the surface-active properties of WPC or WPC-hydrolysate may improve various properties of the spray-dried microcapsules compared to control samples. The study produced microcapsules loaded with YME using different carrier combinations and evaluated their physicochemical, functional, structural, antioxidant, and morphological characteristics.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Shahida Anusha Siddiqui, Muhammad Qudrat Ullah Farooqi, Shuva Bhowmik, Zahra Zahra, M. M. Chayan Mahmud, Elham Assadpour, Ren-You Gan, Mohammad Saeed Kharazmi, Seid Mahdi Jafari
Summary: Microfluidics and nanofluidics techniques show great potential in encapsulating bioactive compounds in various industries. They offer advantages such as improved stability, bioavailability, and solubility of bioactives, along with controlled release and protection against degradation. However, further studies are needed to fully explore the potential efficacy of these techniques in food processing and encapsulation.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Food Science & Technology
Wanli Zhang, Hamed Ahari, Zhengke Zhang, Seid Mahdi Jafari
Summary: Due to environmental pollution and health concerns caused by plastic packaging films, research on degradable food packaging films (DFPFs) based on biopolymers and nano-additives has become popular. Studies have shown that DFPFs containing silica (SiO2) are potential alternatives to plastic packaging materials.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Food Science & Technology
Alireza Sadeghi, Maryam Ebrahimi, Fahimeh Hajinia, Mohammad Saeed Kharazmi, Seid Mahdi Jafari
Summary: This review discusses the correlation between sourdough and high-throughput meta-omics strategies, as well as the importance of sourdough in food biotechnology. The use of foodOmics provides insights into the microbial metabolome of sourdough and its effects on the techno-nutritional potentials of baked goods, such as their nutritional, textural, and sensorial properties, as well as their mold-free shelf-life.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Food Science & Technology
Christian O. Diaz-Ovalle, Seid Mahdi Jafari
Summary: Evaporators are crucial equipment in the food processing industry and can be found in various sectors such as sugar, fruit juices, dairy products, edible oils, tomato paste, and coffee. To reduce energy consumption, multiple-effect evaporators (MEEs) are recommended, where the vapor from one stage is used to heat the next stage. MEEs come in different designs and can be equipped with vapor compression systems and steam ejectors for better energy efficiency. This article provides a comprehensive overview of the fundamentals, design, simulation, control, and application of MEEs in the food industry, discussing recent advancements in the field.
FOOD ENGINEERING REVIEWS
(2023)
Article
Food Science & Technology
Dina Shahrampour, Seyed M. A. Razavi
Summary: In this study, the effect of incorporating rosemary essential oil (REO) nanoemulsions with different droplet sizes (98.14 nm and 148.04 nm) and concentrations (0%, 2%, and 4% v/v) in Eremurus luteus root gum (ELRG) coating solution on the microbial, chemical, and sensory qualities of chicken fillets during cold storage was investigated. The results showed that the active ELRG coating significantly reduced the pH, TBA value, and total viable microbial count (TVC) of chicken meat samples compared to the uncoated sample. The concentration of REO nanoemulsions had a greater impact on the properties of the active ELRG coatings than the size of their droplets. Coated samples containing 4% (v/v) REO nanoemulsions exhibited higher antimicrobial and antioxidant activities.
FOOD SCIENCE & NUTRITION
(2023)
Article
Engineering, Chemical
Katarzyna Samborska, Khashayar Sarabandi, Renata Tonon, Ayhan Topuz, Emrah Eroglu, Figen Kaymak-Ertekin, Narjes Malekjani, Seid Mahdi Jafari
Summary: Spray drying of sugar-rich foods often leads to problems such as high stickiness, reduced drying efficiency, and lower yield. Various methods have been explored to overcome these issues, including the use of conventional carriers like maltodextrin and gum Arabic, as well as novel carriers with health-promoting properties. Modifying raw materials using membrane techniques to decrease sugar content and increase glass transition temperature is another approach. Additionally, reducing drying temperature by using dehumidified air has shown promising results in reducing stickiness and minimizing the need for excessive carrier usage.
Article
Food Science & Technology
Wanli Zhang, Maryam Azizi-Lalabadi, Swarup Roy, Shamimeh Azimi Salim, Roberto Castro-Munoz, Seid Mahdi Jafari
Summary: The increasing interest in biodegradable, biocompatible, sustainable, and renewable biomaterials has led to the development of biopolymeric food packaging films (BFPFs) with green ingredients and strategies. This article discusses the use of Maillard reaction as a promising approach to enhance the performance of degradable BFPFs by modifying or combining biopolymer molecules with additives. The study highlights that Maillard reaction can improve the properties of BFPFs through effective cross-linking and provide functional additives with antibacterial and antioxidant activities. Rating: 8/10.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
