Article
Chemistry, Multidisciplinary
Ermides Chavez-Baldovino, Carlos A. Malca-Reyes, Roberto Masso, Peter Feng, Adrian Camacho, Janeth Sarmiento, Justin I. Borrero Negron, Yomaira J. Pagan-Torres, Liz M. Diaz-Vazquez
Summary: In this study, carrageenan membranes with different concentrations of titanium dioxide nanoparticles (TiO2 NPs) and Ni/CeO2 were used to prepare a novel fuel cell electrode for the oxidation of ethanol. The physicochemical properties of each membrane were characterized, and the carrageenan nanocomposite with 5 wt % TiO2 NPs showed the highest ionic conductivity (2.08 x 10(-4) S/cm). The CR5% membrane was mixed with Ni/CeO2 to prepare the working electrode, and cyclic voltammetry measurements showed peak current density values of 9.52 and 12.22 mA/cm(2) for the oxidation of ethanol over CR5% + Ni/CeO2 at forward and reverse scan voltages, respectively. The CR5% + Ni/CeO2 membrane was found to be more efficient in the oxidation of ethanol compared with commercially available Nafion membranes containing Ni/CeO2.
Article
Biotechnology & Applied Microbiology
Melanie H. Hughes, Patricia I. Leonardi, Diego B. Genovese
Summary: This study investigates the effects of carrageenan concentration, salt concentration, and KCl center dot CaCl2 ratio on the gelation properties of carrageenans from Sarcopeltis skottsbergii and Sarcothalia crispata. The results show that higher concentrations of carrageenan and salt increase gel strength but also increase turbidity. Increasing the KCl fraction also increases gel strength. The optimal compositions predicted by the models are in line with the observed responses. Considering the increasing demand for carrageenan in the food industry, S. skottsbergii and S. crispata could be potential sources of these biopolymers.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Food Science & Technology
Anna Vincova, Kristyna Santova, Vendula Kurova, Alena Kratochvilova, Veronika Halamkova, Marketa Suchankova, Eva Lorencova, Daniela Sumczynski, Richardos Nikolaos Salek
Summary: The study aimed to evaluate the effects of different algal hydrocolloids (κ-carrageenan, η-carrageenan, furcellaran, and sodium alginate) at three concentrations (0.50%, 0.75%, and 1.00%) on the physicochemical, viscoelastic, textural, and organoleptic properties of model cream cheese. The samples with κ-carrageenan showed the highest viscoelastic moduli and hardness values. Increasing the concentrations of the tested hydrocolloids resulted in higher viscoelastic moduli and hardness values. It is recommended to use 0.50%-0.75% (w/w) κ-carrageenan for softer-consistency cream cheese or 1.00% (w/w) furcellaran and sodium alginate. A higher concentration of κ-carrageenan (>0.75% w/w) is recommended for a more rigid consistency.
Article
Food Science & Technology
Myat NOE. Khin, Shabbir Ahammed, Fang Zhong
Summary: This study explored the potential use of DTAF for labeling polysaccharides with different functional groups, especially anionic functional groups, without affecting their physio-chemical properties. The results showed that DTAF labeling did not impact the gelation properties and stability of polysaccharides, while maintaining their mechanical strength and visibility.
Article
Polymer Science
Lester C. Geonzon, Kei Hashimoto, Tatsuro Oda, Shingo Matsukawa, Koichi Mayumi
Summary: This study investigated the viscoelastic properties and temperature-dependent hierarchical structure of carrageenan gels using various methods, and found that different gels exhibited different responses and structural characteristics.
Article
Biochemistry & Molecular Biology
Maria Froeba, Maximilian Grosse, Christian Setz, Pia Rauch, Janina Auth, Lucas Spanaus, Jan Muench, Natalia Ruetalo, Michael Schindler, Martina Morokutti-Kurz, Philipp Graf, Eva Prieschl-Grassauer, Andreas Grassauer, Ulrich Schubert
Summary: This study demonstrates that iota-carrageenan, among other types of carrageenans extracted from red seaweed, exhibits antiviral activity against SARS-CoV-2 and its variants, making it a potential prophylaxis and treatment option, independent of present and potentially future strains.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Agriculture, Multidisciplinary
Shuang Li, Songyi Lin, Pengfei Jiang, Zhijie Bao, Xueqing He, Na Sun
Summary: The contribution and mechanism of different hydration characteristics of kappa-/iota-carrageenan on the gelling properties of shrimp myofibrillar protein were studied. It was found that an appropriate amount of carrageenan enhanced the gel strength, water-holding capacity, and viscoelastic properties of the gel, while excessive carrageenan caused fragmentation of the gel network. Different types of carrageenan had different effects on the hardness and tenderness of the gel, which may be attributed to their interaction with myosin.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Construction & Building Technology
Asma Boukhatem, Kamal Bouarab, Ammar Yahia
Summary: The effect of kappa-iota carrageenan on the rheological behavior, hydration kinetics, and strength development of cement-based materials was investigated. The results showed that the addition of kappa-iota carrageenan increased the flowability and structural stability of cement suspensions. However, when combined with high-range water reducer (HRWR), the effect of kappa-iota carrageenan was reduced. Furthermore, the addition of kappa-iota carrageenan delayed the hardening time of cement suspensions, but had no significant impact on early-age compressive strength development.
ACI MATERIALS JOURNAL
(2022)
Article
Chemistry, Analytical
Yanqin Sun, Xudong Zhu, Xixi Shen, Wei Wang
Summary: The study developed a rapid and accurate method for measuring carrageenan content in livestock and poultry meat using UHPLC-MS/MS. By employing a triple quadrupole mass spectrometer and gradient elution on a chromatographic column, successful separation and quantification of carrageenan was achieved.
INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY
(2021)
Article
Agriculture, Dairy & Animal Science
Dimitrios Kouzounis, Jos A. Hageman, Natalia Soares, Joris Michiels, Henk A. Schols
Summary: This study demonstrates that fiber-degrading enzymes can enhance nutrient digestibility and fiber fermentability in broilers, particularly in wheat-based diets, by breaking down fibers into smaller, more easily fermentable structures. Their impact is believed to be higher in wheat-based diets due to the complex structure of maize fibers and the higher nutritional value of maize.
Article
Biology
Guelcin Ozcan Ates, Mueserref Otkun
Summary: This study determined the yeast load and species in the oral mycobiota of young individuals. The results showed the presence of Candida species in the oral cavity of individuals aged 18-25. These findings are important for understanding the oral health and microbiota of young individuals.
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2023)
Article
Clinical Neurology
Zelal Zuhal Kaya, Mete Bora Tuzuner, Betul Sahin, Emel Akgun, Fehime Aksungar, Sebile Koca, Muhittin Serdar, Sevki Sahin, Nilgun Cinar, Sibel Karsidag, Hasmet Ayhan Hanagasi, Meltem Kilercik, Mustafa Serteser, Ahmet Tari K. Baykal
Summary: In this study, a biomarker-based, high-throughput screening test was developed for accurate diagnosis of Alzheimer's disease, which can significantly reduce cost and time.
CURRENT ALZHEIMER RESEARCH
(2022)
Article
Religion
W. Gil Shin
Summary: The rare word ΣΚΗΝΟΠΟΙΟΖ may reveal the socio-economic nature of Paul, but historically reconstructing his trade has proven difficult. Luke's choice of vocabulary may be for rhetorical purposes, enhancing the word's symbolic value.
Article
Chemistry, Applied
E. V. Sokolova, A. O. Kravchenko, N. V. Sergeeva, V. N. Davydova, L. N. Bogdanovich, I. M. Yermak
CARBOHYDRATE POLYMERS
(2020)
Article
Biochemistry & Molecular Biology
Irina M. Yermak, Viktoria N. Davydova, Anna O. Kravchenko, Dmitry A. Chistyulin, Evgeniya A. Pimenova, Valery P. Glazunov
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Chemistry, Medicinal
Irina M. Yermak, Aleksandra V. Volod'ko, Eleonora Khasina, Viktoriya N. Davydova, Evgeniy A. Chusovitin, Dmitry L. Goroshko, Anna O. Kravchenko, Tamara F. Solov'eva, Victor V. Maleev
Article
Chemistry, Applied
E. Sokolova, A. O. Kravchenko, N. Sergeeva, A. Kalinovsky, V. P. Glazunov, L. N. Bogdanovich, I. M. Yermak
Summary: The research revealed that sulfated galactans and carrageenans have varied effects on complement system activation, with the sulfation degree playing a key role in their binding capacity to specific complement components.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Medicinal
Viktoriya N. Davydova, Irina V. Sorokina, Aleksandra V. Volod'ko, Ekaterina V. Sokolova, Marina S. Borisova, Irina M. Yermak
Article
Biochemistry & Molecular Biology
Irina Yermak, Stanislav Anastyuk, Anna Kravchenko, William Helbert, Valery Glazunov, Andrey Shulgin, Pavel Spirin, Vladimir Prassolov
Summary: New insights into the hybrid structure of kappa/beta-carrageenan in the red alga Tichocarpus crinitus have been obtained, demonstrating its potential to inhibit the replication of various viruses, particularly the human immunodeficiency virus. The study revealed the antiviral activity of carrageenan oligosaccharides against lentiviral particles pseudotyped with different envelope proteins, with CRG oligosaccharides showing significantly higher activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Medicinal
Natalia V. Krylova, Anna O. Kravchenko, Olga V. Iunikhina, Anastasia B. Pott, Galina N. Likhatskaya, Aleksandra V. Volod'ko, Tatyana S. Zaporozhets, Mikhail Y. Shchelkanov, Irina M. Yermak
Summary: The study compared the antiviral activities of different structural types of red algae carrageenans (CRGs) against HSV-1 and ECHO-1, revealing that CRGs have varying effects on different stages of virus infection due to their structural features.
Article
Biochemistry & Molecular Biology
Irina M. Yermak, Anna O. Kravchenko, Eleonora Khasina, Ekaterina S. Menchinskaya, Evgeny A. Pislyagin, Ekaterina Sokolova, Galina N. Likhatskaya, Dmitry L. Aminin
Summary: The study demonstrates that the CRG/Ech complex has anti-inflammatory effects by reducing the production of ROS and NO, and can prevent endotoxin-induced damage and lower the levels of proinflammatory cytokines.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Anna Kravchenko, Stanislav Anastyuk, Valery Glazunov, Ekaterina Sokolova, Vladimir Isakov, Irina Yermak
Summary: The sulfated polysaccharides from cystocarpic plants of Mazzaella parksii were fractionated and determined to consist of several carrageenans with different structures and molecular weights. Nine gelling fractions and one non-gelling fraction were obtained through stepwise fractionation with KCl. The structures of the main fractions were investigated in detail, and their ability to activate the complement system was also studied.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Natalia V. V. Krylova, Vladimir I. I. Gorbach, Olga V. V. Iunikhina, Anastasia B. B. Pott, Valery P. P. Glazunov, Anna O. O. Kravchenko, Mikhail Y. Y. Shchelkanov, Irina M. M. Yermak
Summary: This study investigated the antiherpetic activity of complexes of kappa- and sigma-carrageenans with echinochrome A, as well as their liposomal forms, showing promising results in inhibiting HSV-1 infection. The liposomal form of the sigma-CRG/Ech complex demonstrated three times higher virus-inhibiting activity compared to the complex itself, indicating potential for the development of effective antiherpetic drugs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Anna O. Kravchenko, Ekaterina S. Menchinskaya, Vladimir V. Isakov, Valery P. Glazunov, Irina M. Yermak
Summary: Comparative structural analysis was carried out on gelling polysaccharides from A. flabelliformis and M. pacificus, and their effect on human colon cancer cell lines was studied. The polysaccharides from M. pacificus predominantly contained kappa units, while the polysaccharides from A. flabelliformis predominantly contained iota units. Oligosaccharides derived from these polysaccharides showed antiproliferative effects on the tested cell lines, with kappa/iota-oligosaccharides having a greater effect on colony formation and iota/kappa-oligosaccharides having a stronger inhibitory effect on cell migration.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)