期刊
CARBOHYDRATE POLYMERS
卷 228, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2019.115378
关键词
Antimicrobial adhesion; Borneol; Chitosan; Stereochemistry; Skin flora
资金
- National Natural Science Foundation of China [21574008, 21204004]
- Fundamental Research Funds for the Central Universities of China [PYBZ1806, BHYC1705B]
Antimicrobial modifications of chitosan usually endow the products with strong bactericidal activities. However, if the products come into direct contact with human skin, the skin flora, which is beneficial to human health, may be damaged. To address this issue, we developed a stereochemical antimicrobial strategy by grafting borneol 4-formylbenzoate to chitosan using a stable Schiff base bond; this process yielded borneol-modified chitosan (BMC) as a novel antimicrobial material. This material was challenged with gram-negative Escherichia coli, gram-positive Bacillus subtilis, and Aspergillus niger. All tests showed excellent antimicrobial adhesive properties. Guinea pig skin experiments further demonstrated that BMC did not damage the skin flora. Owing to the antimicrobial mechanism of borneol stereochemistry, BMC successfully defended against pathogens and protected the skin flora. Thus, this material may have excellent potential applications in multifunctional textiles, healthcare, and flexible skin electronics.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据