Review
Biochemistry & Molecular Biology
Helge Waldum, Reidar Fossmark
Summary: Chronic inflammation is associated with the development of carcinogenesis in the digestive organs. This review focuses on chronic hepatitis, chronic inflammatory bowel disease, and chronic gastritis, which are conditions that predispose individuals to malignancy. The mechanisms by which chronic inflammation can cause malignancy are discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Psychology, Multidisciplinary
Xue Tian, Yuan-hong Li, Lan-zhi Deng, Wen-ze Han, Dan Pu, Xiang-long Han, Shu-fang Du, Wei Deng
Summary: Anxiety and depression play a mediating role in the relationship between gastrointestinal conditions and oral health in orthodontic patients. In particular, anxiety has a significant mediating effect. Future clinical practices and monitoring should pay more attention to the psychological status of patients.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Angela E. Dean, Francois Reichardt, Sayeepriyadarshini Anakk
Summary: Sex differences exist in nutrient metabolism and hormone regulation in the gastrointestinal tract, possibly influenced by nuclear receptors. Some nuclear receptors show different activity and target gene expression between males and females, potentially affecting overall metabolic decisions.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2021)
Article
Public, Environmental & Occupational Health
Kirsten R. R. Panton, James P. P. Fitzpatrick, Carmela F. F. Pestell
Summary: Fetal alcohol spectrum disorder (FASD) is underdiagnosed in Australia due to a lack of trained clinicians and diagnostic services. This project aimed to increase FASD knowledge and diagnostic capacity nationwide through training clinics, diagnostic clinics, and community education sessions. The project led to a significant increase in FASD diagnoses and positive feedback from community education sessions. Participants in the training clinics showed increased knowledge and confidence in FASD diagnosis. This evaluation highlights the benefits of a coordinated approach to FASD prevention, assessment, diagnosis, and training.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Biochemistry & Molecular Biology
N. Perales-Garcia, D. Tovar-Ramirez, M. G. Martinez-Morales, B. P. Ceballos-Vazquez, D. A. Corona-Rojas, M. A. Salcedo-Meza, A. Garrido-Mora, F. Vega-Villasante, H. Nolasco-Soria
Summary: This study provides the first report on the digestive tract pH of the pygmy octopus. The pH of the digestive tract regions was found to be lower than 7.0 and did not differ significantly between wild and captive octopuses. The digestive gland had the lowest pH values, but they were still above 5.0.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Oncology
Nina Afshar, S. Ghazaleh Dashti, Victoria Mar, Luc te Marvelde, Sue Evans, Roger L. Milne, Dallas R. English
Summary: Women diagnosed with melanoma have better survival rates than men, and factors such as tumor thickness and tumor site play a significant role in reducing the survival gap between genders.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Environmental Sciences
Nadine Schubert, Viviana Pena, Vinicius W. Salazar, Paulo A. Horta, Pedro Neves, Claudia Ribeiro, Francisco Otero-Ferrer, Fernando Tuya, Fernando Espino, Kathryn Schoenrock, Laurie C. Hofmann, Line Le Gall, Rui Santos, Joao Silva
Summary: The study investigates the photosynthetic and calcification mechanisms of different species of Atlantic rhodoliths, finding significant differences and influences from local environmental conditions.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Biology
Samira Lafraxo, Meryem Souaidi, Mohamed El Ansari, Lahcen Koutti
Summary: Colorectal cancer is a common malignancy and the leading cause of cancer death worldwide. Wireless capsule endoscopy is the most frequent method for detecting precancerous digestive diseases. Scientists have proposed computational techniques to automatically segment anomalies from endoscopic images, addressing the time-consuming and tedious manual examination for doctors.
Article
Chemistry, Physical
Feng Chen, Manish Shetty, Meng Wang, Hui Shi, Yuanshuai Liu, Donald M. Camaioni, Oliver Y. Gutierrez, Johannes A. Lercher
Summary: The rate of acid-base-catalyzed dehydration of alcohols depends strongly on the solvent and the environment of the acid sites. Brønsted acidic sites in large-pore zeolites catalyze cyclohexanol dehydration at significantly higher rates than hydrated hydronium ions in aqueous phase. The difference in turnover rates between the two solvents is much larger in large-pore zeolites compared to medium-pore zeolites. Additionally, the mechanism of cyclohexanol dehydration varies depending on the zeolite structure, with E1 elimination being dominant except for a monomer dehydration route on H-MFI which follows an E2-type mechanism.
Article
Public, Environmental & Occupational Health
Liza A. Hoveling, Aart C. Liefbroer, Ute Bultmann, Nynke Smidt
Summary: Education and occupational prestige were inversely associated with MetS, while income was not related. Health behaviors played a partial role in explaining these associations, with smoking and physical activity being the key factors. Individuals with higher SEP had a lower risk of MetS mainly due to non-smoking, less excessive alcohol intake, and better diet quality, despite being less physically active.
PREVENTIVE MEDICINE
(2021)
Article
Agriculture, Multidisciplinary
Ralf Greiner
Summary: The study showed that the current in vitro model does not sufficiently mimic the in vivo situation in birds to evaluate the bioefficacy of phytase products under real conditions. However, it can be used as a complementary tool in the pre-selection of promising phytase candidates to reduce the number of feeding trials in the initial screening phase.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Psychology, Clinical
Daniel J. Paulus, Matthew W. Gallagher, Michael J. Zvolensky, Adam M. Leventhal
Summary: This study found that anxiety sensitivity has a predictive effect on adolescent alcohol problems, but not on their alcohol consumption; anxiety indirectly mediated the impact of anxiety sensitivity on alcohol problems throughout high school; race/ethnicity did not moderate the relationships between anxiety sensitivity, anxiety, and alcohol outcomes.
BEHAVIOUR RESEARCH AND THERAPY
(2021)
Article
Engineering, Mechanical
Changgen Yan, Huaixin Li, Yuling Shi, Hengxing Lan, Linhao Zhao, Han Bao, Zhuolong Jia, Zherui Liang
Summary: This paper analyzes the impact of repeated improper treatment on bridge site slopes and proposes solutions based on long-term field monitoring data. The results show that the destruction of the bridge is mainly attributed to the deformation of the landslide and the sliding force induced by natural rainfall. By adding antislide piles, increasing the cross-sectional area of the bridge pier foundation, and installing drainage pipes, the safety of the bridge is effectively guaranteed.
ENGINEERING FAILURE ANALYSIS
(2023)
Article
Nutrition & Dietetics
Liza A. Hoveling, Aart C. Liefbroer, Ute Bultmann, Nynke Smidt
Summary: Higher education and income are positively associated with MetS remission, with education having a partial mediation effect through healthier behaviors. However, income is directly associated with MetS remission irrespective of health behaviors, while occupational prestige shows no significant association.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2021)
Article
Psychology, Clinical
Warren Logge, Andrew Baillie, Paul Haber, Ellen Towers, Benjamin C. Riordan, Kirsten Morley
Summary: This study aimed to evaluate the role of sex in the relationship between daily alcohol consumption, stress, and craving in response to baclofen treatment. The results showed that baclofen abolished the association between stress and drinking in females, but this was not observed in males.
ADDICTIVE BEHAVIORS
(2023)
Article
Peripheral Vascular Disease
Shohei Chatani, Ryota Tsukii, Kyohei Nagasawa, Takaaki Hasegawa, Shinichi Murata, Mina Kato, Hidekazu Yamaura, Hiroaki Onaya, Keitaro Matsuo, Yoshiyuki Watanabe, Yoshitaka Inaba
Summary: This study investigated the difficulty in removing totally implantable venous access devices (TIVADs) and identified associated risk factors. Interventional radiology (IR) approaches for difficult removal were also explored. The results showed that indwelling duration and subcutaneous leakage of fluid were significant risk factors for difficult removal. IR techniques were found to be minimally invasive and useful in some cases.
JOURNAL OF VASCULAR ACCESS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Neerav Goyal, Max Hennessy, Erik Lehman, Wenxue Lin, Antonio Agudo, Wolfgang Ahrens, Stefania Boccia, Paul Brennan, Hermann Brenner, Gabriella Cadoni, Cristina Canova, Chu Chen, David Conway, Maria Paula Curado, Luigino Dal Maso, Alexander W. Daudt, Valeria Edefonti, Eleonora Fabianova, Leticia Fernandez, Silvia Franceschi, Werner Garavello, Maura Gillison, Richard B. Hayes, Claire Healy, Rolando Herrero, Ivana Holcatova, Jossy L. Kanda, Karl Kelsey, Bo T. Hansen, Rosalina Koifman, Pagona Lagiou, Carlo La Vecchia, Fabio Levi, Guojun Li, Jolanta Lissowska, Rossana Mendoza Lopez, Daniele Luce, Gary Macfarlane, Dana Mates, Keitaro Matsuo, Michael McClean, Ana Menezes, Gwenn Menvielle, Hal Morgenstern, Kirsten Moysich, Eva Negri, Andrew F. Olshan, Tamas Pandics, Jerry Polesel, Mark Purdue, Loredana Radoi, Heribert Ramroth, Lorenzo Richiardi, Stimson Schantz, Stephen M. Schwartz, Diego Serraino, Oxana Shangina, Elaine Smith, Erich M. Sturgis, Beata Swiatkowska, Peter Thomson, Thomas L. Vaughan, Marta Vilensky, Deborah M. Winn, Victor Wunsch-Filho, Guo-Pei Yu, Jose P. Zevallos, Zuo-Feng Zhang, Tongzhang Zheng, Ariana Znaor, Paolo Boffetta, Mia Hashibe, Yuan-Chin A. Lee, Joshua E. Muscat
Summary: This study analyzed the relationship between cigarette smoking, alcohol consumption, and head and neck cancer risk factors in less developed and more developed countries. The results showed that the duration of smoking and alcohol consumption had different effects on the risk of specific cancer sites depending on the country's level of development. These findings suggest that the degree of industrialization and economic development affects the relationship between smoking, alcohol, and head and neck cancer.
Article
Ophthalmology
Akiko Hanyuda, Atsushi Goto, Masahiro Nakatochi, Yoichi Sutoh, Akira Narita, Shiori Nakano, Ryoko Katagiri, Kenji Wakai, Naoyuki Takashima, Teruhide Koyama, Kokichi Arisawa, Issei Imoto, Yukihide Momozawa, Kozo Tanno, Atsushi Shimizu, Atsushi Hozawa, Kengo Kinoshita, Taiki Yamaji, Norie Sawada, Masao Iwagami, Kenya Yuki, Kazuo Tsubota, Kazuno Negishi, Keitaro Matsuo, Masayuki Yamamoto, Makoto Sasaki, Shoichiro Tsugane, Motoki Iwasaki
Summary: This study conducted a Mendelian randomization analysis to assess the causal association between genetically predicted glycemic traits and the risk of primary open-angle glaucoma (POAG). The results did not provide strong evidence to support the association between genetically predicted glycemic traits and POAG in the Japanese population.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Takaaki Hasegawa, Haruyuki Takaki, Hiroshi Kodama, Keitaro Matsuo, Takashi Yamanaka, Atsuhiro Nakatsuka, Motoshi Takao, Hideo Gobara, Sadao Hayashi, Yoshitaka Inaba, Koichiro Yamakado
Summary: The purpose of this study was to explore the impact of ablative margin depicted by CT immediately after RF ablation on reducing LTP for CRC lung metastases. A retrospective study was conducted on 70 patients who underwent RF ablation for CRC lung metastases. The results indicated that an ablative margin of at least 2 mm is important to reduce LTP after RF ablation for CRC lung metastases.
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Hematology
Kimimori Kamijo, Yoshimitsu Shimomura, Akihito Shinohara, Shohei Mizuno, Minoru Kanaya, Yoshiaki Usui, Sung-Won Kim, Takahide Ara, Ishikazu Mizuno, Takuro Kuriyama, Hideyuki Nakazawa, Ken-ichi Matsuoka, Shigeru Kusumoto, Nobuo Maseki, Masaki Yamaguchi, Takashi Ashida, Makoto Onizuka, Takahiro Fukuda, Yoshiko Atsuta, Eisei Kondo
Summary: By comparing the effects of Flu/Bu2 and Flu/Bu4 on patients with non-Hodgkin lymphoma undergoing allogeneic hematopoietic cell transplantation, the study found that Flu/Bu4 was associated with higher nonrelapse mortality and lower 5-year overall survival compared to Flu/Bu2.
ANNALS OF HEMATOLOGY
(2023)
Article
Hematology
Yui Kambara, Nobuharu Fujii, Yoshiaki Usui, Akira Yamamoto, Hisao Higo, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Keiko Fujii, Ken-ichi Matsuoka, Yoshinobu Maeda
Summary: Non-infectious pulmonary complications (NIPCs) after allogeneic hematopoietic stem cell transplantation (HSCT) are associated with poor outcomes. Early initiation of corticosteroid therapy is associated with long-term survival in NIPCs.
INTERNATIONAL JOURNAL OF HEMATOLOGY
(2023)
Article
Ophthalmology
Shinichiro Doi, Shuhei Kimura, Shoko Saito, Makoto Inoue, Toshiya Sakurai, Akira Kobori, Toshio Hisatomi, Hisanori Imai, Shoji Kuriyama, Ippei Takasu, Mio Morizane Hosokawa, Yusuke Shiode, Ryo Matoba, Etsuji Suzuki, Yuki Morizane
Summary: The effects of macular intraretinal hemorrhage (IRH) and macular hole (MH) on best-corrected visual acuity (BCVA) after displacement of submacular hemorrhage (SMH) due to retinal arterial macroaneurysm (RAM) rupture were compared in this study. The results showed that patients with IRH and MH had worse BCVA postoperatively, lower central retinal thickness, and discontinuity in the external limiting membrane and ellipsoid zone. Both IRH(+)MH(+) and IRH(+)MH(-) were associated with postoperative BCVA.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2023)
Article
Medicine, General & Internal
Yoshiaki Usui, Yukari Taniyama, Mikiko Endo, Yuriko N. Koyanagi, Yumiko Kasugai, Isao Oze, Hidemi Ito, Issei Imoto, Tsutomu Tanaka, Masahiro Tajika, Yasumasa Niwa, Yusuke Iwasaki, Tomomi Aoi, Nozomi Hakozaki, Sadaaki Takata, Kunihiko Suzuki, Chikashi Terao, Masanori Hatakeyama, Makoto Hirata, Kokichi Sugano, Teruhiko Yoshida, Yoichiro Kamatani, Hidewaki Nakagawa, Koichi Matsuda, Yoshinori Murakami, Amanda B. Spurdle, Keitaro Matsuo, Yukihide Momozawa
Summary: This study reveals that certain genetic variants associated with Helicobacter pylori infection can increase the risk of gastric cancer. Individuals carrying these genetic variants and infected with H. pylori have an even higher risk of developing gastric cancer.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Ryohei Fujimoto, Etsuji Suzuki, Saori Kashima, Kazufumi Nakamura, Hiromichi Naito, Atsunori Nakao, Hiroshi Ito, Takashi Yorifuji
Summary: This study investigated the associations between short-term heat exposure and the risk of cardiovascular disease in elderly individuals in Japan, with a focus on the effects of rainy seasons. The study found that heat exposure during the month after the rainy season was associated with an increased risk of cardiovascular disease.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Oncology
Yoshiaki Usui, Hidemi Ito, Kota Katanoda, Tomohiro Matsuda, Yoshinobu Maeda, Keitaro Matsuo
Summary: The introduction of rituximab has led to a decline in mortality rates of non-Hodgkin lymphoma in both Japan and the United States, despite an increase in incidence. However, the trends in mortality rates have differed between the two countries, with the mortality rate declining continuously in the United States but stopping in Japan.
Review
Oncology
Yoshiaki Usui, Yukihide Momozawa
Summary: Rare germline pathogenic variants in cancer-predisposing genes have a significant impact on clinical practice. Existing personalized medicine approaches based on European populations may not fully apply to other populations, as we discovered differences in associations between cancer-predisposing genes and diseases in the Japanese population. Our research highlights the importance of population and region-specific studies for improved personalized medicine and a better understanding of disease mechanisms.
Article
Multidisciplinary Sciences
Yukari Okawa, Etsuji Suzuki, Toshiharu Mitsuhashi, Toshihide Tsuda, Takashi Yorifuji
Summary: This study examined the relationship between HbA1c levels and subsequent CKD development in non-diabetic individuals. The results showed no association between HbA1c in the prediabetic range and subsequent CKD development.
SCIENTIFIC REPORTS
(2023)
Article
Oncology
Yukihiro Sugimoto, Yuriko N. Koyanagi, Yukino Kawakatsu, Isao Oze, Yukari Taniyama, Yumiko Kasugai, Tsutomu Tanaka, Tetsuya Abe, Masahiro Tajika, Yasuhiro Shimizu, Hidemi Ito, Kenji Wakai, Keitaro Matsuo
Summary: Alcohol is metabolized to acetaldehyde and acetate through the actions of alcohol dehydrogenase and aldehyde dehydrogenase. The ADH1B rs1229984 polymorphism is associated with drinking habits and the risk of esophageal cancer. Mediation analysis showed that this genetic variant increases the risk of esophageal cancer by affecting alcohol metabolism and drinking intensity.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Hiroshi Tsuge, Daisuke Kawakita, Yukari Taniyama, Isao Oze, Yuriko N. Koyanagi, Megumi Hori, Kayo Nakata, Hiromi Sugiyama, Isao Miyashiro, Izumi Oki, Yoshikazu Nishino, Kota Katanoda, Yuri Ito, Akiko Shibata, Tomohiro Matsuda, Shinichi Iwasaki, Keitaro Matsuo, Hidemi Ito
Summary: This study aimed to assess subsite-specific survival trends for head and neck cancer patients in Japan. The study found that while there was an overall improvement in 5-year survival, there were variations in survival rates among different subsites.
Article
Oncology
Isao Oze, Hidemi Ito, Yuriko N. Koyanagi, Sarah Krull Abe, Md. Shafiur Rahman, Md. Rashedul Islam, Eiko Saito, Prakash C. Gupta, Norie Sawada, Akiko Tamakoshi, Xiao-Ou Shu, Ritsu Sakata, Reza Malekzadeh, Ichiro Tsuji, Jeongseon Kim, Chisato Nagata, San-Lin You, Sue K. Park, Jian-Min Yuan, Myung-Hee Shin, Sun-Seog Kweon, Mangesh S. Pednekar, Shoichiro Tsugane, Takashi Kimura, Yu-Tang Gao, Hui Cai, Akram Pourshams, Yukai Lu, Seiki Kanemura, Keiko Wada, Yumi Sugawara, Chien-Jen Chen, Yu Chen, Aesun Shin, Renwei Wang, Yoon-Ok Ahn, Min-Ho Shin, Habibul Ahsan, Paolo Boffetta, Kee Seng Chia, You-Lin Qiao, Nathaniel Rothman, Wei Zheng, Manami Inoue, Daehee Kang, Keitaro Matsuo
Summary: This study found that BMI is associated with BTC mortality in Asians, with cholelithiasis appearing to contribute to this association. Additionally, obesity appears to increase BTC risk without cholelithiasis.
INTERNATIONAL JOURNAL OF CANCER
(2023)
