Chemoradiation and granulocyte-colony or granulocyte macrophage-colony stimulating factors (G-CSF or GM-CSF): time to think out of the box?

Radiation therapy and immunotherapy: what is the optimal timing or sequencing?

(2018) Maureen L Aliru et al.   Immunotherapy

Abscopal effect of radiotherapy combined with immune checkpoint inhibitors

(2018) Yang Liu et al.   Journal of Hematology & Oncology

Radiation therapy and immunotherapy—a potential combination in cancer treatment

(2018) N. Asna et al.   Current Oncology

A clinical study of polyethylene glycol recombinant human granulocyte colony-stimulating factor prevention neutropenia syndrome in patients with esophageal carcinoma and lung cancer after concurrent chemoradiotherapy

(2017) Fang Liu et al.   Journal of Cancer Research and Therapeutics

Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial

(2017) Corinne Faivre-Finn et al.   LANCET ONCOLOGY

Safety and activity of pembrolizumab in patients with locally advanced or metastatic urothelial cancer (KEYNOTE-012): a non-randomised, open-label, phase 1b study

(2017) Elizabeth R Plimack et al.   LANCET ONCOLOGY

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

(2017) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

A randomized, open-label, Phase III clinical trial of nivolumab vs. therapy of investigator’s choice in recurrent squamous cell carcinoma of the head and neck: A subanalysis of Asian patients versus the global population in checkmate 141

(2017) Naomi Kiyota et al.   ORAL ONCOLOGY

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

(2017) Dung T. Le et al.   SCIENCE

Dosimetric predictors of acute hematologic toxicity during concurrent intensity-modulated radiotherapy and chemotherapy for anal cancer

(2016) P. Franco et al.   Clinical & Translational Oncology

Radiation Therapy Noncompliance and Clinical Outcomes in an Urban Academic Cancer Center

(2016) Nitin Ohri et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The immune system and cancer evasion strategies: therapeutic concepts

(2016) S. Muenst et al.   JOURNAL OF INTERNAL MEDICINE

Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage

(2016) Irina Ushach et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF

(2016) Tsuguhide Takeshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel GM-CSF-based vaccines: One small step in GM-CSF gene optimization, one giant leap for human vaccines

(2016) Ting-Wei Yu et al.   Human Vaccines & Immunotherapeutics

GM-CSF: An immune modulatory cytokine that can suppress autoimmunity

(2015) Palash Bhattacharya et al.   CYTOKINE

Safety and Survival With GVAX Pancreas Prime and Listeria Monocytogenes–Expressing Mesothelin (CRS-207) Boost Vaccines for Metastatic Pancreatic Cancer

(2015) Dung T. Le et al.   JOURNAL OF CLINICAL ONCOLOGY

G-CSF and GM-CSF in Neutropenia

(2015) Hrishikesh M. Mehta et al.   JOURNAL OF IMMUNOLOGY

Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy

(2015) Palash Bhattacharya et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial

(2015) Encouse B Golden et al.   LANCET ONCOLOGY

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

(2015) Julie Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Can dosimetric parameters predict acute hematologic toxicity in rectal cancer patients treated with intensity-modulated pelvic radiotherapy?

(2015) Juefeng Wan et al.   Radiation Oncology

Intensity-Modulated Radiotherapy versus 3-Dimensional Conformal Radiotherapy Strategies for Locally Advanced Non-Small-Cell Lung Cancer

(2015) Ugur Selek et al.   Balkan Medical Journal

Role of Local Radiation Therapy in Cancer Immunotherapy

(2015) Sandra Demaria et al.   JAMA Oncology

Consequences of irradiation on bone and marrow phenotypes, and its relation to disruption of hematopoietic precursors

(2014) Danielle E. Green et al.   BONE

Ipilimumab Plus Sargramostim vs Ipilimumab Alone for Treatment of Metastatic Melanoma

(2014) F. Stephen Hodi et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

(2014) Roy S. Herbst et al.   NATURE

Feasibility of omitting clinical target volume for limited-disease small cell lung cancer treated with chemotherapy and intensity-modulated radiotherapy

(2014) Shuhua Cai et al.   Radiation Oncology

GM-CSF Promotes the Immunosuppressive Activity of Glioma-Infiltrating Myeloid Cells through Interleukin-4 Receptor- 

(2013) G. Kohanbash et al.   CANCER RESEARCH

Hematologic Toxicity in RTOG 0418: A Phase 2 Study of Postoperative IMRT for Gynecologic Cancer

(2013) Ann H. Klopp et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Risk factors for hematological toxicity of chemotherapy for bone and soft tissue sarcoma

(2013) ZHENGXIAO OUYANG et al.   Oncology Letters

Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy

(2012) L. van de Laar et al.   BLOOD

Comparative Effectiveness of Filgrastim, Pegfilgrastim, and Sargramostim as Prophylaxis Against Hospitalization for Neutropenic Complications in Patients With Cancer Receiving Chemotherapy

(2011) Derek Weycker et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial

(2011) Christopher M Nutting et al.   LANCET ONCOLOGY

Radiation Enhances Regulatory T Cell Representation

(2010) Evelyn L. Kachikwu et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Meta-Analysis of Concomitant Versus Sequential Radiochemotherapy in Locally Advanced Non–Small-Cell Lung Cancer

(2010) Anne Aupérin et al.   JOURNAL OF CLINICAL ONCOLOGY

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Limited-Stage Small Cell Lung Cancer: Current Chemoradiotherapy Treatment Paradigms

(2010) T. E. Stinchcombe et al.   ONCOLOGIST

Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer

(2009) Celestia S. Higano et al.   CANCER

Chemoradiation in locally advanced cervical carcinoma: An analysis of cisplatin dosing and other clinical prognostic factors

(2009) Elizabeth K. Nugent et al.   GYNECOLOGIC ONCOLOGY

Systemic effects of local radiotherapy

(2009) Silvia C Formenti et al.   LANCET ONCOLOGY

T-Cell Responses to Survivin in Cancer Patients Undergoing Radiation Therapy

(2008) D. Schaue et al.   CLINICAL CANCER RESEARCH