Cancer Liquid Biopsy Using Integrated Microfluidic Exosome Analysis Platforms

Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip

(2019) Peng Zhang et al.   Nature Biomedical Engineering

A Novel Tissue‐Based Liver–Kidney‐on‐a‐Chip Can Mimic Liver Tropism of Extracellular Vesicles Derived from Breast Cancer Cells

(2019) Hongzhu Tian et al.   Biotechnology Journal

Integrated Analysis of Exosomal Protein Biomarkers on Alternating Current Electrokinetic Chips Enables Rapid Detection of Pancreatic Cancer in Patient Blood

(2018) Jean M. Lewis et al.   ACS Nano

An Exosome-Based Vaccine Platform Imparts Cytotoxic T Lymphocyte Immunity Against Viral Antigens

(2018) Simona Anticoli et al.   Biotechnology Journal

Extracellular Vesicles in Oncology: Progress and Pitfalls in the Methods of Isolation and Analysis

(2018) Donatella Lucchetti et al.   Biotechnology Journal

Exosomes Enter Vaccine Development: Strategies Meeting Global Challenges of Emerging Infections

(2018) Alois Jungbauer   Biotechnology Journal

Single-Exosome-Counting Immunoassays for Cancer Diagnostics

(2018) Chunchen Liu et al.   NANO LETTERS

An Exosome-Based Vaccine Platform Imparts Cytotoxic T Lymphocyte Immunity Against Viral Antigens

(2018) Simona Anticoli et al.   Biotechnology Journal

Extracellular Vesicles in Oncology: Progress and Pitfalls in the Methods of Isolation and Analysis

(2018) Donatella Lucchetti et al.   Biotechnology Journal

Exosomes Enter Vaccine Development: Strategies Meeting Global Challenges of Emerging Infections

(2018) Alois Jungbauer   Biotechnology Journal

ctDNA and CTCs in Liquid Biopsy – Current Status and Where We Need to Progress

(2018) Martin H.D. Neumann et al.   Computational and Structural Biotechnology Journal

A Magnetic-Based Microfluidic Device for On-Chip Isolation and Detection of Tumor-Derived Exosomes

(2018) Huiying Xu et al.   ANALYTICAL CHEMISTRY

Torquetenovirus detection in exosomes enriched vesicles circulating in human plasma samples

(2018) Francesco Martelli et al.   Virology Journal

Exosomes for Non-Invasive Cancer Monitoring

(2018) Kalimuthu Kalishwaralal et al.   Biotechnology Journal

Optimizing Multiplexed Detections of Diabetes Antibodies via Quantitative Microfluidic Droplet Array

(2017) Kai Duan et al.   Small

Exosome separation using microfluidic systems: size-based, immunoaffinity-based and dynamic methodologies

(2017) Fang Yang et al.   Biotechnology Journal

Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires

(2017) Takao Yasui et al.   Science Advances

Clinical application of a microfluidic chip for immunocapture and quantification of circulating exosomes to assist breast cancer diagnosis and molecular classification

(2017) Shimeng Fang et al.   PLoS One

An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer

(2017) Li-Guo Liang et al.   Scientific Reports

Integrated Magneto–Electrochemical Sensor for Exosome Analysis

(2016) Sangmoo Jeong et al.   ACS Nano

Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices

(2016) Jina Ko et al.   ANALYST

Electrochemical Sandwich Immunosensor for Determination of Exosomes Based on Surface Marker-Mediated Signal Amplification

(2016) Ximena Doldán et al.   ANALYTICAL CHEMISTRY

Extracellular vesicles concentration is a promising and important parameter for industrial bioprocess monitoring

(2016) Apolonija Bedina Zavec et al.   Biotechnology Journal

Autophagy and the endo/exosomal pathways in health and disease

(2016) Margarita-Elena Papandreou et al.   Biotechnology Journal

AC Electrokinetic Fast Mixing in Non-Parallel Microchannels

(2016) Fang Yang et al.   CHEMICAL ENGINEERING COMMUNICATIONS

Ultrasensitive microfluidic analysis of circulating exosomes using a nanostructured graphene oxide/polydopamine coating

(2016) Peng Zhang et al.   LAB ON A CHIP

A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis

(2016) Zheng Zhao et al.   LAB ON A CHIP

Development of an aptasensor for electrochemical detection of exosomes

(2016) Qing Zhou et al.   METHODS

Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20 nm

(2016) Benjamin H. Wunsch et al.   Nature Nanotechnology

Isolation of extracellular vesicle from blood plasma using electrophoretic migration through porous membrane

(2016) Siwoo Cho et al.   SENSORS AND ACTUATORS B-CHEMICAL

Extracellular vesicles concentration is a promising and important parameter for industrial bioprocess monitoring

(2016) Apolonija Bedina Zavec et al.   Biotechnology Journal

Autophagy and the endo/exosomal pathways in health and disease

(2016) Margarita-Elena Papandreou et al.   Biotechnology Journal

Integrated Microfluidic Lectin Barcode Platform for High-Performance Focused Glycomic Profiling

(2016) Yuqin Shang et al.   Scientific Reports

Real time and label free profiling of clinically relevant exosomes

(2016) Abu Ali Ibn Sina et al.   Scientific Reports

Smartphone-enabled optofluidic exosome diagnostic for concussion recovery

(2016) Jina Ko et al.   Scientific Reports

Acoustic Purification of Extracellular Microvesicles

(2015) Kyungheon Lee et al.   ACS Nano

Clonal analysis of individual human embryonic stem cell differentiation patterns in microfluidic cultures

(2015) Darek J. Sikorski et al.   Biotechnology Journal

Exosome isolation: a microfluidic road-map

(2015) A. Liga et al.   LAB ON A CHIP

Clonal analysis of individual human embryonic stem cell differentiation patterns in microfluidic cultures

(2015) Darek J. Sikorski et al.   Biotechnology Journal

Detecting Exosomes Specifically: A Multiplexed Device Based on Alternating Current Electrohydrodynamic Induced Nanoshearing

(2014) Ramanathan Vaidyanathan et al.   ANALYTICAL CHEMISTRY

Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrack

(2014) David Henderson et al.   Biotechnology Journal

Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology

(2014) Mei He et al.   LAB ON A CHIP

Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

(2014) Shailender Singh Kanwar et al.   LAB ON A CHIP

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

(2014) Hyungsoon Im et al.   NATURE BIOTECHNOLOGY

Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles

(2013) Junsung Rho et al.   ACS Nano

Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles

(2013) Zongxing Wang et al.   LAB ON A CHIP

Inertial Focusing for Tumor Antigen-Dependent and -Independent Sorting of Rare Circulating Tumor Cells

(2013) E. Ozkumur et al.   Science Translational Medicine

Microfluidic filtration system to isolate extracellular vesicles from blood

(2012) Ryan T. Davies et al.   LAB ON A CHIP

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

(2012) Huilin Shao et al.   NATURE MEDICINE

Dielectrophoretic Separation of Prostate Cancer Cells

(2012) Fang Yang et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

Microfluidic Mixing: A Review

(2011) Chia-Yen Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Microfluidic isolation and transcriptome analysis of serum microvesicles

(2009) Chihchen Chen et al.   LAB ON A CHIP

Chip–NMR biosensor for detection and molecular analysis of cells

(2008) Hakho Lee et al.   NATURE MEDICINE