Article
Green & Sustainable Science & Technology
Ranjit Gurav, Shashi Kant Bhatia, Tae-Rim Choi, Hyun-Joong Kim, Hong-Ju Lee, Jang-Yeon Cho, Sion Ham, Min-Ju Suh, Sang-Hyun Kim, Sun-Ki Kim, Dong-Won Yoo, Yung-Hun Yang
Summary: This study reports a newly isolated halotolerant strain Oceanisphaera arctica YHY1 capable of hydrolyzing seafood processing waste chitin biomass under high salt conditions, leading to stable electricity generation. By utilizing the by-products and metabolites from chitin degradation as electron donors, O. arctica YHY1 can generate electric current. Additionally, the involvement of outer membrane-bound cytochromes and extracellular redox mediators in the electron transfer mechanism was revealed through cyclic voltammetry investigation, FTIR, and XRD analysis of structural and functional group changes in chitin after degradation.
Article
Agricultural Engineering
Sha Long, Lin Zhao, Jinchen Chen, Juhee Kim, Ching-Hua Huang, Spyros G. Pavlostathis
Summary: The transformation of tetracycline in microbial fuel cells was mainly due to adsorption, with implications for the inhibition of biofilm activity and changes in microbial populations. The MFC-Fenton cathode proved to be an efficient and energy-saving process for tetracycline removal compared to anodic bio-oxidation.
BIORESOURCE TECHNOLOGY
(2021)
Article
Agricultural Engineering
Rashmi Kiran, Ravineet Yadav, Devangi Sathe, Sunil A. Patil
Summary: Using saline electrolytes with halophilic CO2-fixing lithotrophic microbial catalysts is seen as a promising strategy for an energy-efficient microbial electrosynthesis (MES) process for CO2 utilization. In this study, a marine microbial community dominated by Vibrio and Clostridium spp. was used to produce organic acids from CO2, achieving high production rates and energetic efficiency in saline conditions compared to non-saline electrolytes commonly used in other MES studies.
BIORESOURCE TECHNOLOGY
(2023)
Article
Chemistry, Physical
Chengzhi Wang, Yi Xing, Kangning Zhang, Huizi Zheng, Ya-nan Zhang, Xiaolin Zhu, Xing Yuan, Jiao Qu
Summary: A photocathode-microbial electrochemical coupling system (PC-MFC) using black phosphorus-doped titanium dioxide nanobelt (BP/TB) as a photocatalyst was constructed to degrade hydroxychloroquine (HCQ, used to treat COVID-19). The degradation efficiency of HCQ (100 mg/L) in the coupling system reached 73.7% within 8 hours, higher than photocatalysis (69.5%), MFC (25.6%), and adsorption (9.6%). The PC-MFC achieved complete degradation of HCQ (100 mg/L) within 96 hours, significantly higher than the MFC (51.1%).
JOURNAL OF POWER SOURCES
(2023)
Article
Environmental Sciences
Anina James
Summary: Microbial fuel cell (MFC) is a bio-electrochemical system that uses electrogenic bacteria to generate electricity. By utilizing wastewater as feed, MFC can generate clean electricity while treating the wastewater. However, there are challenges in scalability and commercialization of this technology, which can be overcome by the use of ceramics. Ceramics can provide chemical and structural stability as separators, chassis, or electrodes in MFCs, and they are low-cost, eco-friendly, and readily available.
ENVIRONMENTAL RESEARCH
(2022)
Article
Engineering, Environmental
Huimin Wang, Xiaoyan Qi, Siyu Chen, Xia Wang
Summary: In this study, breeding wastewater was efficiently treated using an electroactive microbial community screened from the native microorganisms of the wastewater in microbial fuel cells. The results showed good power generation and high pollutants removal efficiency. The morphology characterization demonstrated the formation of a thick biofilm by the screened electroactive microbial community. Microbial community analysis revealed an increase in microorganisms associated with electricity generation and pollutant degradation, while pathogenic microorganisms were greatly decreased. These findings suggest that the MFC constructed using the screened electroactive microbial community can be a sustainable method for breeding wastewater treatment.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Environmental Sciences
Mohd Jahir Khan, Sovik Das, Vandana Vinayak, Deepak Pant, M. M. Ghangrekar
Summary: This study explored the electrogenic properties of diatoms by comparing their effects on the electrical potential of microbial fuel cells (MFC). It was found that diatoms enhanced the output voltage of the MFC. Additionally, the fixed diatom cells at the anode showed an increase in lipid production and the formation of complex compounds during operation. This suggests that diatoms can substitute bacteria in MFCs to produce bioelectricity and other valuable compounds.
Article
Environmental Sciences
Wenchao Xue, Yifan He, Sahawat Yumunthama, Nutkritta Udomkittayachai, Yunxia Hu, Allan Sriratana Tabucanon, Xiaoyuan Zhang, Tonni Agustiono Kurniawan
Summary: The OsMFC integrates forward osmosis into microbial fuel cell to achieve efficient organic removal, bioenergy generation, and high-quality water extraction. Chemical cleaning method with 0.2% NaClO is effective in removing organic foulants, and optimizing operating parameters can enhance power density.
Article
Chemistry, Physical
Xiao-Li Yang, Tao Li, Yang-Guang Xia, Rajendra Prasad Singh, Hai-Liang Song, Heng Zhang, Ya-Wen Wang
Summary: This study investigated the performance of an ecological floating bed-microbial fuel cell (EFB-MFC) coupled system for electricity generation and nitrogen removal. Results showed that introducing plants into the MFC system reduced resistance and increased voltage, while also improving NH4+-N and TN removal efficiency. Water spinach system showed the best performance, but rotten roots of windmill grass released extra NH4+-N which impaired nitrogen removal. Radial oxygen loss and root exudates played significant roles in enhancing electricity generation and nitrogen removal. Electrical stimulation of enzyme activity related to nitrogen removal and migration of NH4+-N contributed to enhancing nitrogen removal.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Agricultural Engineering
Tamirat Redae Gebreslassie, Phan Khanh Thinh Nguyen, Hyon Hee Yoon, Jihyeon Kim
Summary: The study investigated a hybrid process of dark fermentation (DF) and microbial fuel cell (MFC), termed sDFMFC, for simultaneous H2 and electricity production from Saccharina japonica in a single reactor. The results showed that sDFMFC exhibited considerably enhanced energy recovery and confirmed the co-production of H2 and electricity. The process demonstrated a diverse microbial community suitable for microbial conversion of organic substrates.
BIORESOURCE TECHNOLOGY
(2021)
Article
Biophysics
Dan Sun, Bin Xie, Jiahao Li, Xuzhan Huang, Jiawang Chen, Fang Zhang
Summary: A chitin-carrying microbial fuel cell (MFC) based dissolved oxygen (DO) sensor was developed for long-term and inexpensive monitoring of DO. The sensor showed comparable performance to commercial sensors and had a long lifetime of over half a year. Field tests demonstrated the excellent performance and reliability of this low-cost MFC sensor.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Engineering, Chemical
Yangfan Song, Xinxin Wang, Yaling Liu, Hongwei Chen, Chao Zhao, Libin Liu, Hejia Jiang, Lou Zhu, Tianchao Ai
Summary: A novel type of pulsed anaerobic fluidized bed microbial fuel cell (PAFB-MFC) was studied, which showed better electrochemical performance and shorter wastewater treatment time compared to the conventional anaerobic fluidized bed microbial fuel cell (AFB-MFC).
Article
Environmental Sciences
Benhang Li, Dandan Xu, Li Feng, Yongze Liu, Liqiu Zhang
Summary: This review systematically introduced the advances and prospects of aquatic plant coupled with sediment microbial fuel cell (AP-SMFC), including research bibliometric results, reaction mechanisms, performance, and current challenges and future perspectives. It can serve as a guide for new entrants to the field and the further development of AP-SMFC application.
ENVIRONMENTAL POLLUTION
(2022)
Article
Energy & Fuels
Yasser A. Attia, Mohamed Samer, Mahmoud S. M. Mohamed, Elshaimaa Moustafa, Mohamed Salah, Essam M. Abdelsalam
Summary: This study presents a method to maximize the electrical power production from microbial fuel cells (MFCs) by coating the electrodes using nanomaterials. The nanocoated electrodes demonstrated higher voltage stability and power density compared to common electrodes. Additionally, the coulombic efficiency of MFCs with graphitic carbon nitride nanosheets coating was found to be higher than other materials tested.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Biotechnology & Applied Microbiology
Xiaoya Zheng, Shanshan Hou, Charles Amanze, Zichao Zeng, Weimin Zeng
Summary: It has been found that adding magnetic nanoparticles can significantly improve the electricity generation efficiency and COD removal efficiency of microbial fuel cells. By enhancing the biocatalytic activity of the anode, the performance of MFCs is improved. This method is cost-effective and easy to implement.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2022)
Article
Energy & Fuels
Suresh S. Suryawanshi, Prajakta P. Kamble, Ranjit Gurav, Yung-Hun Yang, Jyoti P. Jadhav
Summary: This study investigates the production of biochar from various agricultural and non-agricultural waste biomass for the sorption of methylene blue (MB) dye. The researchers optimized the pyrolysis temperature, dye solution pH, incubation temperature, and time using response surface methodologies (RSM). The results showed that water hyacinth biochar exhibited excellent sorption capability for MB dye and could effectively reduce its toxicity.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Energy & Fuels
Prangya Ranjan Rout, Mukesh Goel, Anee Mohanty, Daya Shankar Pandey, Nirmalya Halder, Sanjay Mukherjee, Shashi Kant Bhatia, Naresh Kumar Sahoo, Sunita Varjani
Summary: This review highlights the valorisation of wastewater during hydrothermal liquefaction (HTL) of biomass, focusing on the role of microalgae in wastewater utilization. The study findings suggest that the selection of appropriate technology is dependent on the characteristics of the microalgae. Recommendations for potential research opportunities are provided to improve the viability of HTL wastewater valorisation.
BIOENERGY RESEARCH
(2023)
Article
Green & Sustainable Science & Technology
A. E. Atabani, Eyas Mahmoud, Muhammed Aslam, Salman Raza Naqvi, Dagmar Juchelkova, Shashi Kant Bhatia, Irfan Anjum Badruddin, T. M. Yunus Khan, Anh Tuan Hoang, Petr Palacky
Summary: The global market for fuel pellets is growing due to coal substitutes, but sustainability and biomass availability are major issues. Spent coffee grounds can be used to produce high heating value fuel pellets, but burning 100% SCG leads to high NO R emissions and low boiler efficiency. Mixing SCG with other biomass improves combustion performance. Further research is needed on the combustion and emissions of defatted spent coffee grounds.
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2023)
Article
Chemistry, Physical
Chayanika Putatunda, Manya Behl, Preeti Solanki, Samriti Sharma, Shashi Kant Bhatia, Abhishek Walia, Ravi Kant Bhatia
Summary: Biohydrogen is considered a versatile future fuel that can replace fossil fuels in various sectors, and photofermentation is an attractive approach due to its efficiency and reduced environmental impacts. However, there are still significant challenges in commercial biohydrogen production through photofermentation. This review provides updated information on new technologies and discusses the prospects for the future of green biohydrogen production.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Review
Agricultural Engineering
Vinod Kumar, Pedro Brancoli, Vivek Narisetty, Stephen Wallace, Dimitris Charalampopoulos, Brajesh Kumar Dubey, Gopalakrishnan Kumar, Amit Bhatnagar, Shashi Kant Bhatia, Mohammad J. Taherzadeh
Summary: The management of a large amount of food waste, equivalent to 1.3 billion tons, is a major challenge. Bread waste (BW) is a promising feedstock for biorefineries, and this review focuses on its potential for sustainable production of important chemicals. The availability of over 100 million tons of BW as a feedstock for biorefineries is discussed, along with examples of platform chemicals produced from BW, such as ethanol, lactic acid, succinic acid, and 2,3-butanediol. The review compares BW-based production of these metabolites with other feedstocks. It also addresses logistic and supply chain challenges associated with using BW as feedstock, and concludes with a discussion on life cycle analysis and comparison with other feedstocks.
BIORESOURCE TECHNOLOGY
(2023)
Article
Agricultural Engineering
Jeyaprakash Dharmaraja, Sutha Shobana, Sundaram Arvindnarayan, Rusal Raj Francis, Rajesh Banu Jeyakumar, Rijuta Ganesh Saratale, Veeramuthu Ashokkumar, Shashi Kant Bhatia, Vinod Kumar, Gopalakrishnan Kumar
Summary: During the pretreatment of lignocellulose biomass, reducing sugars are released and can be used for the production of biofuels and other products. Innovative greener pretreatment techniques are being considered to improve the digestibility of lignocellulosic materials and remove hemicellulose/lignin to yield valid bioproducts.
BIORESOURCE TECHNOLOGY
(2023)
Article
Agricultural Engineering
Shashi Kant Bhatia, Ranjit Gurav, Do-Hyun Cho, Byungchan Kim, Hee Ju Jung, Su Hyun Kim, Tae -Rim Choi, Hyun-Joong Kim, Yung -Hun Yang
Summary: In this study, fourteen types of biochar produced from seven different biomasses at 300 degrees C and 600 degrees C were tested for their ability to remove phenolics including furfural and hydroxymethylfurfural (HMF). Eucheuma spinosum biochar (EB-BC 600) showed the highest adsorption capacity for furfural (258.94 +/- 3.2 mg/g) and HMF (222.81 +/- 2.3 mg/g). Detoxified hydrolysates using EB-BC 600 biochar resulted in significantly increased production of polyhydroxyalkanoates (PHA).
BIORESOURCE TECHNOLOGY
(2023)
Review
Agricultural Engineering
Nitin Kumar Singh, Manish Yadav, Vijai Singh, Hirendrasinh Padhiyar, Vinod Kumar, Shashi Kant Bhatia, Pau-Loke Show
Summary: Artificial intelligence (AI) and machine learning (ML) are currently being used in multiple domains, including the monitoring and design of biological wastewater treatment systems (WWTS). This paper reviews the available information on the applications of AI and ML models in WWTS, presenting bibliometric analyses, model descriptions, specific applications, and major findings. Predominantly used models in biological wastewater treatment include artificial neural networks (ANN), fuzzy logic (FL) algorithms, random forest (RF), and long short-term memory (LSTM), which are tested for predictive control of effluent parameters such as biological oxygen demand (BOD), chemical oxygen demand (COD), nutrient parameters, solids, and metallic substances. Commonly used model performance indicators for accuracy analysis include root mean squared error (RMSE), mean square error (MSE), and determination coefficient (DC). Additionally, this study summarizes the outcomes of various models.
BIORESOURCE TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Hong-Ju Lee, Hee Ju Jung, Byungchan Kim, Do-Hyun Cho, Su Hyun Kim, Shashi Kant Bhatia, Ranjit Gurav, Yun-Gon Kim, Sang-Won Jung, Hyun June Park, Yung-Hun Yang
Summary: This study aims to investigate the effect of heterologous phasins on the production of polyhydroxybutyrate (PHB) in E. coli and determine the best combination of phaP genes. By introducing a combination of phaP genes from a high-producing strain, Halomonas sp. YLGW01, into E. coli, the resulting strain showed a 2.9-fold increase in PHB production, with increased cell mass and PHB content reaching 65%. This strain also exhibited increased tolerance to inhibitors and could utilize lignocellulosic biomass as a carbon source.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Polymer Science
Vishal Ahuja, Arvind Kumar Bhatt, J. Rajesh Banu, Vinod Kumar, Gopalakrishnan Kumar, Yung-Hun Yang, Shashi Kant Bhatia
Summary: Microbial exopolysaccharides (EPSs) such as xanthan, dextran, gellan, and curdlan have various applications in industries due to their biocompatibility, nontoxicity, and functional characteristics. However, their commercial use in healthcare practices is hindered by biodegradability issues, poor cell adhesion, mineralization, and low enzyme activity. Blending EPSs with other polymers can improve their characteristics and make the composites suitable for diverse applications, especially tissue engineering. More research is needed to address the challenges and commercialize these products.
Editorial Material
Polymer Science
Shashi Kant Bhatia
Review
Environmental Sciences
Eunice O. Babatunde, Ranjit Gurav, Sangchul Hwang
Summary: Plant biomass, especially aquatic plant biomass, has gained significant attention for its potential as an alternative feedstock for bioenergy production. Pretreatment of invasive aquatic plant biomass is necessary to improve the conversion efficiency and yield. This review analyzed existing literature on the pretreatment of aquatic lignocellulosic biomass, highlighting the need for further research on different types of aquatic plants to explore their potential for producing high-value products and biofuels.
WASTE AND BIOMASS VALORIZATION
(2023)
Review
Environmental Sciences
Sonika Kumari, Varruchi Sharma, Savita Soni, Ajay Sharma, Abhinay Thakur, Satish Kumar, Kuldeep Dhama, Anil Kumar Sharma, Shashi Kant Bhatia
Summary: Layered double hydroxides (LDHs) are a class of materials with unique structures and properties that have a wide range of applications. LDHs can be synthesized in a cost-effective and environmentally friendly manner through aqueous synthetic pathways, and they have the advantages of easy modification and controlled release. LDHs have great potential in drug delivery, as they can stabilize drugs, enhance solubility, and control release. Additionally, LDHs have good biocompatibility and cellular uptake. This study demonstrates the applications of LDHs and their hybrids/composites in drug, cosmeceutical, and gene delivery systems.
ENVIRONMENTAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Priyanga Kumar, Noel Nesakumar, Jayashree Gopal, Sakthivel Sivasubramanian, Srinivasan Vedantham, John Bosco Balaguru Rayappan
Summary: This study developed an electrochemical biosensor for measuring MG levels in the plasma of type-2 diabetes mellitus patients. The biosensor showed a wide linear concentration range, high sensitivity, and a 90% correlation with ELISA data. It also exhibited a significant correlation with HbA1c and fasting plasma glucose levels.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Cristina Tortolini, Valeria Gigli, Antonio Angeloni, Federico Tasca, Nguyen T. K. Thanh, Riccarda Antiochia
Summary: The development of a novel voltammetric immunosensor for the detection of salivary MMP-8 at the point-of-care is described. The sensor showed good performance and comparable results to the conventional ELISA method when tested in real saliva samples. This biosensor is single-use, cost-effective, and requires a small quantity of test medium and a short preparation time.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Rimsha B. Jamal, Ulrich Bay Gosewinkel, Elena E. Ferapontova
Summary: Pathogen-triggered infections are a severe global threat to human health. Researchers have developed a fast and inexpensive electrocatalytic aptamer assay for the specific and ultrasensitive detection of E. coli, allowing for timely treatment and prevention. The method is fast, sensitive, and can be used in field and point-of-care applications for analysis of bacteria in the human environment.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Miao Liu, Yuwei Wang, Shanshan Tang, Wei Wang, Axin Liang, Aiqin Luo
Summary: An unlabeled ratiometric molecular imprinted electrochemiluminescence sensor was developed for the determination of trace uric acid using MXene@NaAsc, CdSe@ZnS quantum dots, and molecularly imprinted polymer composites modified glass carbon electrode. This sensor, with easy preparation, great selectivity, and excellent sensitivity, successfully detected uric acid in human serum.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Charlotte Da Silva, Camille Lamarche, Carole Pichereaux, Emmanuelle Mouton-Barbosa, Gauthier Demol, Sebastien Boisne, Etienne Dague, Odile Burlet-Schiltz, Flavien Pillet, Marie-Pierre Rols
Summary: Low-energy electron beams (LEEB) are a safe and practical sterilization solution for industrial applications. To address the limitations of LEEB, we developed a low-energy pulsed electron beam generator (LEPEB) that can effectively and efficiently eradicate bacteria in a wide range of industrial applications.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Daniel Dobrovodsky, Ales Danhel, Daniel Renciuk, Jean-Louis Mergny, Miroslav Fojta
Summary: In this study, N-methyl mesoporphyrin IX (NMM) was utilized as a voltammetric probe for the electrochemical detection of G4s. The detection of NMM was achieved by cyclic voltammetry on a hanging mercury drop electrode (HMDE) with a limit of detection (LOD) of 40 nM. The reduction signal of NMM was found to be significantly higher when G4 oligodeoxynucleotides (G4 ODNs) were present compared to single- or double-stranded ODNs or unfolded ODNs capable of forming G4s. Gradual transition from unstructured single strand to G4, induced by increasing concentrations of the G4 stabilizing K+ ions, was detected for the first time using electrochemical methods. Circular dichroism spectroscopy provided support for the obtained results. This work expands on the utilization of electrochemical probes for DNA secondary structure recognition and offers a proof of principle for the development of novel electroanalytical methods for nucleic acid structure studies.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Mengjiao Zhu, Yu Liu, Meiyue Wang, Tao Liu, Zhenyu Chu, Wanqin Jin
Summary: Early rapid diagnosis of COVID-19 is crucial for reducing the risk of severe symptoms and loss of lung function. Researchers have proposed an ultrafast and ultrasensitive DNA sensor that can accurately detect the virus in a short period of time, with outstanding selectivity.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Fatima-Zahra Ait-Itto, James A. Behan, Mathieu Martinez, Frederic Barriere
Summary: This study investigated the feasibility of using ancient marine sediments as inoculum for bioanode development in microbial fuel cells (MFC). The results showed the presence of two exoelectrogenic bacterial genera in these iron-rich sediments and confirmed that the development of the bioanode derived from the native microbiota. This study has important implications for understanding the role of these bacteria in broader paleoenvironmental phenomena.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Issa Fall, Bastien Doumeche, Sofiene Abdellaoui, Caroline Remond, Harivony Rakotoarivonina, Marjorie Ochs
Summary: This article presents a novel electrochemical tool based on lignin-coated paper electrodes for the detection and characterization of ligninolytic activity. The suitability of this method has been demonstrated using a catalaseperoxidase isolated from Thermobacillus xylanilyticus.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Chenyi Zhuo, Dehong Yu, Jiuying Cui, Zichun Song, Qianli Tang, Xianjiu Liao, Zhao Liu, Ning Xin, Lu Lou, Fenglei Gao
Summary: A label-free detection strategy for quantification of Apolipoprotein A4 (Apo-A4) has been developed based on rolling circle amplification (RCA) and proximity hybridization-induced DNAzyme-driven bipedal DNA walker. This method shows high sensitivity and selectivity for a wide range of protein targets.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Niloufar Fattahi, Jeffrey Reed, Evan Heronemus, Priyasha Fernando, Ryan Hansen, Prathap Parameswaran
Summary: In this study, polyethylene glycol hydrogels were developed as protective coatings for electroactive biofilms, improving their viability under low resource conditions and ammonia-N shocks.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Xiaopeng Hou, Qiongyi Cheng, Hui Wang
Summary: A self-cleaning paper-based microfluidic biosensor was developed using hydrophobic paper decorated with polymeric octadecyl trichlorosilane. The biosensor showed improved performance and could effectively measure the concentration of copper ions in livestock feed and manure.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Yanling Zhang, Jie Wang, Min Liu, Yun Ni, Yao Yue, Dawei He, Ruijiang Liu
Summary: An innovative electrochemical biosensor has been developed for sensitive detection of HER2 protein, an important tumor marker for breast cancer diagnosis and treatment evaluation. The biosensor utilizes specific recognition probes and nanomaterials, along with a unique sensing strategy, to achieve ultra-low detection limit and demonstrate excellent selectivity, reproducibility, and stability.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Humayun Amir, Vasanth Subramanian, Sundaram Sornambikai, Nagamony Ponpandian, Chinnusamy Viswanathan
Summary: In this study, the electrochemical detection of breast cancer biomarker HER2 was successfully achieved using the N-CQDs/GS as the detector. The BSA-modified HER2 Antibody/N-CQDs/GS immunoelectrode preserved excellent activity for the biosensor, while the GS electrode provided high stability and conductivity. The method exhibited a low detection limit and optimal specificity, stability, and reproducibility for detecting HER-2 protein in untreated blood samples from breast cancer patients.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ilona Uzieliene, Anton Popov, Raminta Vaiciuleviciute, Gailute Kirdaite, Eiva Bernotiene, Almira Ramanaviciene
Summary: This review discusses the application of polypyrrole (Ppy), an electroconductive polymer, in cell culture experiments with electrical stimulation (ES) and its potential for tissue regeneration. Ppy can direct ES to cells and stimulate differentiation towards different cell lineages. Different types of Ppy materials and their combination with active molecules are explored.
BIOELECTROCHEMISTRY
(2024)