Review
Environmental Sciences
Claire Lepault, Franck Lecocq
Summary: This study provides a comprehensive survey of country-level mitigation pathways literature, showing variations in research focus among different countries, especially in Africa. The time horizons of 2030 and 2050 are major points of interest, with uneven distribution of research topics across countries reflecting national circumstances and priorities.
ENVIRONMENTAL RESEARCH LETTERS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Dimitra Karapetsa, Arianna Consensi, Giulia Castagnoli, Morena Petrini, Matteo Tonelli, Stefano Gennai, Laura Bazzichi, Filippo Graziani
Summary: The study found a high prevalence and severity of periodontitis among Italian patients with rheumatoid arthritis. Patients with both periodontitis and rheumatoid arthritis were more likely to have moderate to severe RA.
Article
Rheumatology
Sytske Anne Bergstra, Alexandre Sepriano, Arvind Chopra, Lai-Ling Winchow, David Vega-Morales, Karen Salomon-Escoto, Xanthe M. E. Matthijssen, Robert B. M. Landewe
Summary: The age of onset of rheumatoid arthritis (RA) is influenced by geographical latitude. This study investigated the extent to which patient-specific factors and country-level socioeconomic indicators explain this variability. The results showed that patients living closer to the equator have a younger age at RA diagnosis, and this gradient is primarily explained by countries' socioeconomic status.
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Multidisciplinary Sciences
Theis Christian Tonnessen, Arne Olav Melleby, Ida Marie Hauge-Iversen, Emil Knut Stenersen Espe, Mohammed Shakil Ahmed, Thor Ueland, Espen Andre Haavardsholm, Sara Marie Atkinson, Espen Melum, Havard Attramadal, Ivar Sjaastad, Leif Erik Vinge
Summary: Patients with rheumatoid arthritis have an increased risk of heart failure, but the experimental RA model in mice did not cause or modify HF caused by aortic constriction. This suggests that there are other prerequisites for RA-induced cardiac dysfunction.
Article
Rheumatology
Teresa A. Simon, Lixian Dong, Samy Suissa, Kaleb Michaud, Sofia Pedro, Marc Hochberg, Maarten Boers, Johan Askling, Thomas Frisell, Anja Strangfeld, Yvette Meissner, Vadim Khaychuk, Alyssa Dominique, Michael A. Maldonado
Summary: This study evaluated the risk of non-melanoma skin cancer associated with abatacept treatment for rheumatoid arthritis. The results suggest a potential increase in NMSC risk with abatacept use compared to conventional synthetic disease-modifying antirheumatic drugs.
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Rheumatology
Farzin Khosrow-Khavar, Seoyoung C. Kim, Hemin Lee, Su Been Lee, Rishi J. Desai
Summary: The study did not find evidence of increased cardiovascular risk with tofacitinib in patients with RA in a real-world setting. However, tofacitinib was associated with an increased risk of cardiovascular outcomes, although statistically non-significant, in patients with RA with cardiovascular risk factors.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Rheumatology
Dafne Capelusnik, Sizheng Steven Zhao, Annelies Boonen, Nelly Ziade, Clementina Lopez Medina, Maxime Dougados, Elena Nikiphorou, Sofia Ramiro
Summary: This study investigated the association between individual-level and country-level socio-economic factors and health outcomes across different spondyloarthritis phenotypes. The results showed that factors such as gender, education level, marital status, and GDP of the country were associated with health outcomes, with varying degrees of influence. Furthermore, the study revealed that country-level socio-economic factors played a significant role in health outcomes, independent of disease phenotypes.
Article
Multidisciplinary Sciences
Mohammad Movahedi, Angela Cesta, Xiuying Li, Claire Bombardier
Summary: This study described the disease activity trajectories in early and established rheumatoid arthritis (RA). The findings showed better treatment outcomes in early RA compared to established RA, and demonstrated the impact of sociodemographic characteristics and early treatment on disease course.
Review
Rheumatology
Khalid B. Almutairi, Johannes C. Nossent, David B. Preen, Helen I. Keen, Charles A. Inderjeeth
Summary: The prevalence of rheumatoid arthritis varies widely based on population and data collection methods, with an average point prevalence of 51 in 10,000 and average period prevalence of 56 in 10,000. Urban settings tend to have higher RA prevalence than rural areas, potentially due to differences in healthcare access or risk environment. Studies using population databases and validated diagnoses by rheumatologists are more consistent in estimating RA prevalence.
JOURNAL OF RHEUMATOLOGY
(2021)
Article
Rheumatology
James M. Gwinnutt, Husain Alsafar, Kimme L. Hyrich, Mark Lunt, Anne Barton, Suzanne M. M. Verstappen
Summary: The study found that a significant proportion of patients with early RA reduced or stopped their physical activity levels over the first year of MTX treatment. Factors such as smoking, higher disability, and greater socioeconomic deprivation were associated with stopping physical activity.
Article
Rheumatology
Fan Cao, Da-Peng Li, Guo-Cui Wu, Yi-Sheng He, Yu-Chen Liu, Jing-Jing Hou, Qin-Yu Ni, Li-Ming Tao, Zheng-Xuan Jiang, Hai-Feng Pan
Summary: This study provides an overview and analysis of the temporal trends in the prevalence of musculoskeletal disorders in women of childbearing age at global, regional, and national levels over the past 30 years. The results indicate a favorable overall trend in the prevalence of these disorders globally, but there are still 138 countries experiencing unfavorable rising trends. This raises concerns about the timely achievement of the Sustainable Development Goals.
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Rheumatology
Jeffrey A. Sparks, Yinzhu Jin, Soo-Kyung Cho, Seanna Vine, Rishi Desai, Tracy J. Doyle, Seoyoung C. Kim
Summary: This study investigated the prevalence, incidence, and cause-specific mortality of RA-associated interstitial lung disease (RA-ILD) among older US patients with RA. The results showed that RA-ILD was present or developed in nearly 5% of patients, and RA-ILD was associated with excess total, respiratory, and cancer mortality compared with RA without ILD.
Article
Rheumatology
Anthony J. Esposito, Jeffrey A. Sparks, Ritu R. Gill, Hiroto Hatabu, Eric J. Schmidlin, Partha Hota, Sergio Poli, Elaine A. Fletcher, Wesley Xiong, Michelle L. Frits, Christine K. Iannaccone, Maria Prado, Alessandra Zaccardelli, Allison Marshall, Paul F. Dellaripa, Michael E. Weinblatt, Nancy A. Shadick, Ivan O. Rosas, Tracy J. Doyle
Summary: Pulmonary disease is a common manifestation of RA, associated with increased morbidity and mortality. This study found a high prevalence of undiagnosed parenchymal lung disease in RA patients, primarily manifested as preclinical emphysema. High resolution CT scans may be the most effective screening modality for detecting lung abnormalities in RA patients.
Article
Rheumatology
Johanna M. Maassen, Sytske Anne Bergstra, Arvind Chopra, Nimmisha Govind, Elizabeth A. Murphy, David Vega-Morales, Tom W. J. Huizinga, Cornelia F. Allaart
Summary: This study found that RA patients onset above 65 years old include more men and seronegative arthritis, and were initially treated slightly differently than younger patients. However, there were no clinically relevant differences in timing of a next treatment step or response to treatment between different age groups.
Review
Rheumatology
Gregory C. McDermott, Tracy J. Doyle, Jeffrey A. Sparks
Summary: RA-ILD is a serious extra-articular manifestation of RA, with high prevalence throughout the disease course. Autoantibodies like ACPA may play a central role in the development of ILD in RA patients. Further studies are needed to better understand the risk factors, prognosis, and potential therapies for RA-ILD.
CURRENT OPINION IN RHEUMATOLOGY
(2021)
Article
Rheumatology
Santiago Munoz-Fernandez, Teresa Oton-Sanchez, Loreto Carmona, Jaime Calvo-Alen, Alejandro Escudero, Javier Narvaez, Jose Manuel Rodriguez Heredia, Susana Romero Yuste, Paloma Vela, Sara Lujan Valdes, Ana Royo Garcia, Jose Luis Baquero
RHEUMATOLOGY INTERNATIONAL
(2018)
Article
Rheumatology
Teresa Oton, Loreto Carmona, Ana Urruticoechea-Arana, Jaime Calvo-Alen, Maria J. Arteaga, Luis Cea-Calvo
RHEUMATOLOGY INTERNATIONAL
(2019)
Article
Rheumatology
Teresa Oton, Carlos Sastre, Loreto Carmona
Summary: This study explored the perspectives of patients and healthcare professionals on non-radiographic axial spondyloarthritis (nr-axSpA) and identified unmet needs along the patient journey from diagnosis to treatment. Discussions included the appropriateness of terminologies, management of back pain, waiting list issues, and unmet needs from both practitioner's and patient's perspectives. The study also proposed solutions such as strengthening interdisciplinary relationships and providing better information to patients.
CLINICAL RHEUMATOLOGY
(2021)
Review
Rheumatology
Javier Narvaez, Teresa Oton, Judit LLuch, Maribel Mora-Liminana, Joan Miquel Nolla, Estibaliz Loza
Summary: The study found that in patients with active rheumatoid arthritis, biologic-naive patients had a more rapid reduction in disease activity after receiving tocilizumab and sarilumab therapy. However, after 6 to 12 months of treatment, patients tended to have similar treatment responses regardless of the number of previous biologic DMARDs used.
Article
Rheumatology
Teresa Oton, Loreto Carmona, Jose Luis Andreu
Summary: The study identified barriers and facilitators to adherence to methotrexate in patients with rheumatic diseases, including drug-related aspects, patient-physician relationship, social environment, and medical care practicalities. To improve adherence, providing quality information, especially on adverse events, and enhancing shared decision-making are important factors.
MUSCULOSKELETAL CARE
(2022)
Article
Pediatrics
Juan Jose Fernandez-Perez, Paloma Mascaraque-Ruiz, Carlos Martin Gomez, Ignacio Martinez-Caballero, Teresa Oton, Loreto Carmona, Sergio Lerma Lara
Summary: This study aimed to examine the quality of life and daily functioning of Spanish children and adolescents with Stickler syndrome (SS) and estimate the prevalence of associated disease features. The results showed a high variability in syndrome-related manifestations, with a large prevalence of visual and hearing deficits, pain, and maxillofacial alterations.
Article
Rheumatology
Teresa Oton, Loreto Carmona, Jose Luis Andreu
Summary: This study assessed the experience and needs of patients receiving MTX treatment through an online survey. The results showed that patients were not satisfied with the quality of information provided by clinics and had a demand for more and better-quality written or web-based information.
RHEUMATOLOGY INTERNATIONAL
(2023)
Article
Rheumatology
Javier Narvaez, Teresa Oton, Jaime Calvo-Alen, Alejandro Escudero-Contreras, Santiago Munoz-Fernandez, Jose Manuel Rodriguez-Heredia, Susana Romero-Yuste, Paloma Vela-Casasempere, Sara Lujan, Jose Luis Baquero, Loreto Carmona
Summary: Among the poor prognostic factors in rheumatoid arthritis, the presence of interstitial lung disease (ILD) significantly influences treatment selection, with abatacept or rituximab being the preferred options. Other factors such as high disease activity, disability, seropositivity, and erosions do not seem to significantly impact rheumatologists' treatment decisions.
Article
Rheumatology
Jose Rosas, Maria Martin-Lopez, Teresa Oton, Alejandro Balsa, Jaime Calvo-Alen, Raimon Sanmarti, Jesus Tornero, Loreto Carmona
REUMATOLOGIA CLINICA
(2020)
Article
Rheumatology
Javier de Toro, Carlos M. Gonzalez, Luis Cea-Calvo, Maria J. Arteaga, Sabela Fernandez, Loreto Carmona, Teresa Oton
MUSCULOSKELETAL CARE
(2020)
Article
Rheumatology
Carlos Gonzalez, Rafael Curbelo Rodriguez, Juan Carlos Torre-Alonso, Eduardo Collantes, Santos Castaneda, M. Victoria Hernandez, Ana Urruticoechea-Arana, Juan Carlos Nieto-Gonzalez, Javier Garcia, Miguel Angel Abad, Julio Ramirez, Carmen Suarez, Regina Dalmau, Maria Dolores Martin-Arranz, Leticia Leon, Juan Carlos Hermosa, Juan Carlos Obaya, Teresa Oton, Loreto Carmona
REUMATOLOGIA CLINICA
(2018)
Review
Rheumatology
Raquel Almodovar, Pedro Zarco, Teresa Oton, Loreto Carmona
REUMATOLOGIA CLINICA
(2018)
Article
Rheumatology
V. Torrente-Segarra, T. C. Salman Monte, I. Rua-Figueroa, F. Alonso, F. J. Lopez-Longo, M. Galindo-Izquierdo, J. Calvo-Alen, A. Olive-Marques, J. Ibanez-Ruan, L. Horcada, A. Sanchez-Atrio, C. Montilla, R. B. Melero-Gonzalez, E. Diez-Alvarez, V. Martinez-Taboada, J. L. Andreu, O. Fernandez-Berrizbeitia, J. A. Hernandez-Beriain, M. Gantes, B. Hernandez-Cruz, A. Pecondon-Espanol, C. Marras, G. Bonilla, J. M. Pego-Reigosa
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
(2017)
Article
Rheumatology
Victoria Navarro-Compan, Teresa Oton, Estibaliz Loza, Raquel Almodovar, Rafael Ariza-Ariza, Wilson Bautista-Molano, Ruben Burgos-Vargas, Eduardo Collantes-Estevez, Eugenio de Miguel, Carlos Gonzalez-Fernandez, Jordi Gratacos, Sebastian Ibanez, Xavier Juanola, Jose Maldonado-Cocco, Anna Molto, Juan Mulero, Cesar Pacheco-Tena, Cesar Ramos-Remus, Jesus Sanz-Sanz, Rafael Valle-Onate, Pedro Zarco, Helena Marzo-Ortega
REUMATOLOGIA CLINICA
(2020)
