Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo

Hemithioindigos for cellular photopharmacology: desymmetrised molecular switch scaffolds enabling design control over the isomer-dependency of potent antimitotic bioactivity

(2019) Alexander Sailer et al.   CHEMBIOCHEM

Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse

(2019) Pedro Guedes-Dias et al.   CURRENT BIOLOGY

Optical Control of Cardiac Function with a Photoswitchable Muscarinic Agonist

(2019) Fabio Riefolo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Microtubule control of functional architecture in neurons

(2019) Michael T Kelliher et al.   CURRENT OPINION IN NEUROBIOLOGY

In Vivo Photopharmacology

(2018) Katharina Hüll et al.   CHEMICAL REVIEWS

Polarized microtubule dynamics directs cell mechanics and coordinates forces during epithelial morphogenesis

(2018) Amrita Singh et al.   NATURE CELL BIOLOGY

Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held

(2017) Kohgaku Eguchi et al.   JOURNAL OF NEUROSCIENCE

A microtubule-organizing center directing intracellular transport in the early mouse embryo

(2017) J. Zenker et al.   SCIENCE

Structural Basis of cis - and trans -Combretastatin Binding to Tubulin

(2017) Roberto Gaspari et al.   Chem

Photoswitchable anticancer activity via trans–cis isomerization of a combretastatin A-4 analog

(2016) Jonathon E. Sheldon et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death

(2015) Malgorzata Borowiak et al.   CELL

Synthesis, Characterization, and Bioactivity of the Photoisomerizable Tubulin Polymerization Inhibitor azo-Combretastatin A4

(2015) Ashton J. Engdahl et al.   ORGANIC LETTERS

Hemithioindigo—an emerging photoswitch

(2015) Sandra Wiedbrauk et al.   TETRAHEDRON LETTERS

Optical control of antibacterial activity

(2013) Willem A. Velema et al.   Nature Chemistry

Fluorescence lifetime imaging of E-combretastatin uptake and distribution in live mammalian cells

(2011) Roger H. Bisby et al.   EUROPEAN JOURNAL OF CANCER

LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness

(2011) Natalia Caporale et al.   MOLECULAR THERAPY

Kinetic study of the fast thermal cis-to-trans isomerisation of para-, ortho- and polyhydroxyazobenzenes

(2010) Jaume Garcia-Amorós et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

pH-Dependent cis → trans Isomerization Rates for Azobenzene Dyes in Aqueous Solution†

(2009) Nicholas J. Dunn et al.   JOURNAL OF PHYSICAL CHEMISTRY A