The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan

The Gid-complex: an emerging player in the ubiquitin ligase league

(2019) Huaize Liu et al.   BIOLOGICAL CHEMISTRY

Role of Bicaudal C1 in renal gluconeogenesis and its novel interaction with the CTLH complex

(2018) Lucia Carolina Leal-Esteban et al.   PLoS Genetics

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation

(2018) Fabienne Lampert et al.   eLife

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Landscape of nuclear transport receptor cargo specificity

(2017) Marie‐Therese Mackmull et al.   Molecular Systems Biology

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK

(2017) Chen-Song Zhang et al.   NATURE

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes

(2017) Shun-Jia Chen et al.   SCIENCE

Non-linear impact of glutathione depletion on C. elegans life span and stress resistance

(2017) Nadine Urban et al.   Redox Biology

Drugging the undruggables: exploring the ubiquitin system for drug development

(2016) Xiaodong Huang et al.   CELL RESEARCH

Autophagy and primary cilia: dual interplay

(2016) Olatz Pampliega et al.   CURRENT OPINION IN CELL BIOLOGY

Deubiquitination and Activation of AMPK by USP10

(2016) Min Deng et al.   MOLECULAR CELL

Roles of mTOR complexes in the kidney: implications for renal disease and transplantation

(2016) Daniel Fantus et al.   Nature Reviews Nephrology

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

(2016) Alessandro Bitto et al.   eLife

Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

(2015) Carlos T. Pineda et al.   CELL

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

RMND5 from Xenopus laevis Is an E3 Ubiquitin-Ligase and Functions in Early Embryonic Forebrain Development

(2015) Thorsten Pfirrmann et al.   PLoS One

Nutrient Excess and AMPK Downregulation in Incubated Skeletal Muscle and Muscle of Glucose Infused Rats

(2015) Kimberly A. Coughlan et al.   PLoS One

Longevity, aging and rapamycin

(2014) Dan Ehninger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Where is mTOR and what is it doing there?

(2014) Charles Betz et al.   JOURNAL OF CELL BIOLOGY

Elution Profile Analysis of SDS-induced Subcomplexes by Quantitative Mass Spectrometry

(2014) Yves Texier et al.   MOLECULAR & CELLULAR PROTEOMICS

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

Functional interaction between autophagy and ciliogenesis

(2013) Olatz Pampliega et al.   NATURE

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

(2013) Zaiming Tang et al.   NATURE

SOMA: A Single Oligonucleotide Mutagenesis and Cloning Approach

(2013) Thorsten Pfirrmann et al.   PLoS One

Molecular Phylogeny of a RING E3 Ubiquitin Ligase, Conserved in Eukaryotic Cells and Dominated by Homologous Components, the Muskelin/RanBPM/CTLH Complex

(2013) Ore Francis et al.   PLoS One

Exploring the Topology of the Gid Complex, the E3 Ubiquitin Ligase Involved in Catabolite-induced Degradation of Gluconeogenic Enzymes

(2012) Ruth Menssen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MSnbase-an R/Bioconductor package for isobaric tagged mass spectrometry data visualization, processing and quantitation

(2011) Laurent Gatto et al.   BIOINFORMATICS

Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processes

(2011) Martin Sadowski et al.   IUBMB LIFE

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism

(2009) Marnix Jansen et al.   PHYSIOLOGICAL REVIEWS

Control of AMPK-related kinases by USP9X and atypical Lys29/Lys33-linked polyubiquitin chains

(2008) Abdallah K. Al-Hakim et al.   BIOCHEMICAL JOURNAL

The Yeast GID Complex, a Novel Ubiquitin Ligase (E3) Involved in the Regulation of Carbohydrate Metabolism

(2008) Olivier Santt et al.   MOLECULAR BIOLOGY OF THE CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Components of the Vid30c are needed for the rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p inSaccharomyces cerevisiae

(2007) Chris Snowdon et al.   FEMS YEAST RESEARCH