IDOL G51S Variant Is Associated With High Blood Cholesterol and Increases Low-Density Lipoprotein Receptor Degradation

Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins

(2019) Jian Xiao et al.   Science China-Life Sciences

A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis

(2018) Karin E. Bornfeldt et al.   AMERICAN JOURNAL OF PATHOLOGY

Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies—Statement From ATVB CouncilHighlights

(2018) Peggy Robinet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inactivation of the E3 Ubiquitin Ligase IDOL (Inducible Degrader of the Low-Density Lipoprotein Receptor) Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

(2018) Nienke M. van Loon et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ALIMA1variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

(2018) Ying-Yu Zhang et al.   SCIENCE

The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking

(2018) Yacheng Liao et al.   Science China-Life Sciences

Corrigendum: Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

(2017) Yong-Jian Wang et al.   NATURE CELL BIOLOGY

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes

(2017) Jian Wei et al.   Cell Reports

Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterol

(2016) Salam Ibrahim et al.   CARDIOVASCULAR RESEARCH

The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOLNovelty and Significance

(2015) Jessica Kristine Nelson et al.   CIRCULATION RESEARCH

Adverse Effects of Statins - Myths and Reality

(2015) Iveta Simic et al.   CURRENT PHARMACEUTICAL DESIGN

IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population

(2015) Ashish Dhyani et al.   PLoS One

Prevalence of Isolated Diastolic Hypertension and Associated Risk Factors among Different Ethnicity Groups in Xinjiang, China

(2015) Fen Liu et al.   PLoS One

The LXR–Idol Axis Differentially Regulates Plasma LDL Levels in Primates and Mice

(2014) Cynthia Hong et al.   Cell Metabolism

Transgenic Expression of Dominant-Active IDOL in Liver Causes Diet-Induced Hypercholesterolemia and Atherosclerosis in Mice

(2014) Anna C. Calkin et al.   CIRCULATION RESEARCH

Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein

(2013) V. Sorrentino et al.   EUROPEAN HEART JOURNAL

Appropriate Body Mass Index and Waist Circumference Cutoffs for Categorization of Overweight and Central Adiposity among Uighur Adults in Xinjiang

(2013) Shuo Pan et al.   PLoS One

Genetic Determinants of Statin-Induced Low-Density Lipoprotein Cholesterol Reduction

(2012) Daniel I. Chasman et al.   Circulation-Cardiovascular Genetics

Post-transcriptional regulation of lipoprotein receptors by the E3-ubiquitin ligase inducible degrader of the low-density lipoprotein receptor

(2012) Vincenzo Sorrentino et al.   CURRENT OPINION IN LIPIDOLOGY

MYLIP p.N342S polymorphism is not associated with lipid profile in the Brazilian population

(2012) Paulo C J L Santos et al.   Lipids in Health and Disease

Type 2 Diabetes in Xinjiang Uygur Autonomous Region, China

(2012) Yi-Ning Yang et al.   PLoS One

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

(2011) L. Zhang et al.   GENES & DEVELOPMENT

Distinct Functional Domains Contribute to Degradation of the Low Density Lipoprotein Receptor (LDLR) by the E3 Ubiquitin Ligase Inducible Degrader of the LDLR (IDOL)

(2011) Vincenzo Sorrentino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans

(2011) Daphna Weissglas-Volkov et al.   JOURNAL OF CLINICAL INVESTIGATION

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors

(2011) A. C. Calkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demographic history and rare allele sharing among human populations

(2011) S. Gravel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE