Article
Engineering, Chemical
Fatemeh Ahmadpoor, Mahmoud Nasrollahzadeh, Mahsa Mohammad
Summary: This study successfully designed an efficient and green hierarchical copper phosphate-lignosulfonate nanoflowers using an eco-friendly self-assembly method for catalytic reduction of organic dyes in water. Lignosulfonate played a critical role in controlling the size and morphology of Cu-LS nanoflowers, which showed high stability and reusability in catalytic tests.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Ayse Demirbas, Baris Karsli, Ismail Ocsoy
Summary: In this study, two amino acids, Glycine and Phenylalanine, interacted with copper ions to form flower-shaped amino acid-copper hybrid nanostructures. The catalytic activity of these structures was tested using peroxidase-like assays. The morphology and composition of the nanostructures were carefully characterized and optimized. The results of this investigation are expected to have significant implications in various technical and scientific sectors.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Chemistry, Physical
Hossein Jafari-Nodoushan, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Nasrin Samadi
Summary: Organic-inorganic hybrid nanoflowers (HNFs) are hierarchical flower-shaped microstructures composed of organic and inorganic constituents. They have a high surface-to-volume ratio and are mainly used for efficient biocatalysis and highly sensitive biosensing. They also have other important applications. However, there are still unknown aspects and future directions of research in this field.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Article
Polymer Science
Fatih Dogan Koca, Haydar Matz Muhy, Mehmet Gokhan Halici
Summary: This study reports the synthesis of organic-inorganic hybrid nanoflowers (hNFs) using brown macroalgae extract as the organic component. The hNFs exhibited ideal flower morphology and showed excellent catalytic and antioxidant activities, making them suitable as catalyst and antioxidant agents.
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2023)
Article
Green & Sustainable Science & Technology
Yang Liu, Ziyuan Wang, Yuxiao Feng, Yi Jiao, Le Zhong, Geling Kuang, Yingjie Du, Muhammad Bilal, Shiru Jia, Jiandong Cui
Summary: Isoorotic acid-zinc phosphate hybrid nanoflowers (IA-ZP NF) using zinc (II) ions as the inorganic component and isoorotic acid as the organic component have been developed as a new kind of antibacterial material. The IA-ZP NF exhibit enhanced antibacterial activity and low toxicity due to the synergistic effects of zinc (II) release, generation of reactive oxygen species (ROS), and membrane interaction.
SUSTAINABLE MATERIALS AND TECHNOLOGIES
(2022)
Article
Biotechnology & Applied Microbiology
Harshada M. Salvi, Ganapati D. Yadav
Summary: Epoxide hydrolases are enzymes widely found in nature that catalyze the hydrolysis of epoxides to diols without the need for a cofactor. A method for immobilization of epoxide hydrolase based on biomimetic mineralization has been reported, resulting in organic-inorganic hybrid nanoflowers with higher catalytic activity and stability. The nanoflowers, consisting of enzyme epoxide hydrolase and Ca2+ ions, exhibit a unique hierarchical flower-like structure and have been applied for styrene oxide hydrolysis. Factors affecting morphology, catalytic activity, and stability were studied to understand the activity recovery of the synthesized hybrid nanoflowers.
JOURNAL OF BIOTECHNOLOGY
(2021)
Review
Materials Science, Biomaterials
Xiao Liang, Yong Liu, Kai Wen, Wei Jiang, Quanshun Li
Summary: Enzyme immobilization in inorganic hybrid nanoflowers is a biomimetic mineralization method with mild reaction conditions, which helps to obtain ideal biocatalysts. Immobilized enzymes in inorganic hybrid nanoflowers have been successfully used in biocatalysis, producing medical intermediates and biodiesel, as well as in developing biosensors for detecting toxic substances and disease biomarkers.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Review
Chemistry, Analytical
Indra Gandi Subramani, Veeradasan Perumal, Subash C. B. Gopinath, Khor Shing Fhan, Norani Muti Mohamed
Summary: Nanotechnology has seen significant advancements in the past decade, particularly in the field of organic-inorganic hybrid nanoflowers with green synthesis methods. Despite their high surface-to-volume ratio and enzymatic activity, challenges such as low mechanical strength and difficulties in recovery have hindered their wide industrial application.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Miaorong Zhang, Yan Zhang, Chuankai Yang, Chunyun Ma, Jianguo Tang
Summary: Enzyme-inorganic hybrid nanoflowers (HNFs) are a novel hybrid nanomaterial with superior performances, involving classification, synthesis, functionalization, and various potential application areas. The focus of the review is on developing classification, synthesis methods and applications of enzyme-inorganic HNFs in the field of biocatalysis. Current problems and prospects for further study are proposed.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Environmental Sciences
Chao-Yun Feng, Kang-Hong Wang, Shuangfei Li, Dong-Shen Liu, Zhen Yang
Summary: In this work, enzymatic methods using mushroom tyrosinase immobilized as enzyme-metal hybrid composites were developed for efficient removal of phenolic pollutants from industrial wastewaters. The immobilized enzymes showed superior dephenolization efficiency and reusability compared to other supports. The hybrid biocomposites demonstrated complete elimination of typical phenolic pollutants within a short time period and their operability and reusability were enhanced by entrapping or incorporating with magnetic nanoparticles. The magnetic biocatalyst exhibited high dephenolization efficiency after multiple cycles and continuous treatment for at least 24 hours.
Article
Chemistry, Analytical
Huijuan Zhao, Tingting Liu, Lin Cui, Yanhong Li, Fei Yang, Xiaomei Zhang
Summary: A label-free and dual-amplified electrochemical bioanalysis was developed for ultrasensitive detection of the tumor biomarker MUC1, using an inorganic-organic polymer hybrid mimic peroxidase and catalytic hairpin assembly. The biosensor exhibited high sensitivity, low detection limits, and excellent selectivity, showing promise for biomedical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Jiaojiao Gao, Hui Liu, Kexin Wu, Jifeng Yan, Huayu Li, Ruixuan Yang, Cheng Tong, Lingyan Pang, Junqi Li
Summary: In this study, dual-functional nanoflowers Cu-NFs were prepared through a simple method and utilized to construct a sensitive colorimetric biosensor for the detection of carcinoembryonic antigen. The colorimetric sensor showed a wide linear range and low detection limit, with successful application in human serum samples, suggesting promising applications in medical diagnosis and portable detection.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Dongying Zhao, Zhongji Pu, Qiao Su, Yue Zhang, Wenhui Sun, Yongming Bao
Summary: In this study, a novel self-assembled nanoflower structure CaNF@CgkPZ was synthesized, with significantly improved catalytic efficiency and good stability and reusability.
ENZYME AND MICROBIAL TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Dawei Xu, Cong Li, Yuqiu Zi, Dafeng Jiang, Fei Qu, Xian-En Zhao
Summary: A new strategy for cholesterol determination was developed using MOF@MnO2 nanocomposites and hybrid nanoflowers, which greatly improved the stability of enzymes and demonstrated good detection performance and specificity. The concentration of cholesterol showed a positive correlation with fluorescence recovery in the range of 10 to 360 μM, with a low detection limit of 1.57 μM.
Article
Engineering, Chemical
Chen Gao, Bright Appiah, Zhi-Cheng Zou, Bo-Wei Zhang, Jin-Hui Zhou, Chen Yu, Ling-Ling Li, Can Quan, Zhong-Hua Yang
Summary: Organic-inorganic hybrid nanoflowers (hNFs) have attracted extensive attention as a novel enzyme immobilization mode due to their unique high specific surface area and distinctive microstructure. In this study, a NP1-inorganic hNF (NP1-hNF) was prepared by self-assembly co-precipitation method using CaCl2 and BSA. The NP1-hNFs showed significantly enhanced catalytic activity and improved thermal stability compared to the free enzyme. The NP1-hNFs were further entrapped in calcium alginate microbeads for improved reusability, retaining 65% of residual activity after five recycle uses and 96% after 50 days of storage.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Polymer Science
Burcu Onal, Omur Acet, Volha Dzmitruk, Inessa Halets-Bui, Dzmitry Shcharbin, Nalan Ozdemir, Mehmet Odabasi
Summary: A new pure inorganic copper phosphate nanoflowers were synthesized and evaluated for their binding mechanism with human serum albumin under different environmental conditions. The maximum HSA adsorption capacity was found as 225.7 mg/g with Langmuir model determined as the fittest adsorption model.
Article
Polymer Science
Inessa Halets-Bui, Volha Dzmitruk, Viktar Abashkin, Svetlana Loznikova, Omur Acet, Burcu Onal, Nalan Ozdemir, Maria Bryszewska, Mehmet Odabasi, Dzmitry Shcharbin
Summary: Nanoflowers, a special class of nanomaterials, have sparked the interest of scientists due to their high surface-to-volume ratio. Their main value lies in serving as enzyme stabilizers through charge affinity and covalent bonding. The interaction of Cu nanoflowers and Fe3+-attached Cu nanoflowers with fluorescent probes and proteins showed significant differences, highlighting the potential applications of nanoflowers in sorption of fluorescent probes and proteins.
Article
Biochemistry & Molecular Biology
Canan Gulmez, Cevahir Altinkaynak, Merve Turk, Nalan Ozdemir, Onur Atakisi
Summary: Protein-inorganic hybrid nanoflowers show great potential in bionanotechnology due to their ease of preparation, stability, and superior properties. In this study, hemoglobin-inorganic hybrid nanoflowers with different metal ions were synthesized and evaluated for their oxygen carrying capacity and safety as potential blood substitutes. Results indicated that Zn-NF had significant oxygen content and AOC, with low hemolysis rate, high antioxidant capacity, and low oxidative stress index, suggesting it could be a superior artificial oxygen carrier.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Polymer Science
N. Ozdemir, C. Altinkaynak, M. Turk, F. Gecili, S. Tavlasoglu
Summary: This study synthesized and characterized amino acid-metal phosphate hybrid nanoflowers, demonstrating their potential as radical scavengers and antioxidants. The AaHNFs were characterized morphologically and chemically using various techniques, showing superior peroxidase-like activity and antioxidant capabilities compared to free amino acids. These novel AaHNFs could serve as effective natural antioxidants in a range of potential applications.
Article
Chemistry, Multidisciplinary
Burcu Somturk Yilmaz, Serkan Dayan, Nalan Ozdemir, Nilgun Kalaycioglu Ozpozan
Summary: In this study, flower-like enzyme-inorganic hybrid nanoflowers were synthesized for the first time. These nanoflowers were used as catalysts in the reduction of organic pollutants, showing promising catalytic properties for water-based reduction reactions.
Article
Engineering, Electrical & Electronic
Serkan Dayan, Nalan Ozdemir, Mustafa Akbulut, Nilgun Kalaycioglu Ozpozan
Summary: In this study, modified flower-like hybrid nanomaterials were fabricated and tested as Pt-free counter electrodes in dye-sensitized solar cells. The addition of multi-walled carbon nanotubes to the structure significantly improved the photovoltaic parameters, leading to a fivefold increase in power conversion efficiency.
JOURNAL OF ELECTRONIC MATERIALS
(2022)
Article
Anatomy & Morphology
Sezer Demirbuga, Serkan Dayan, Hacer Balkaya
Summary: The aim of this study was to evaluate the drug release, degree of conversion (DC), and surface properties of resin composites containing chlorhexidine (CHX)-loaded mesoporous (mHAP) and nonporous hydroxyapatite (HAP) nanocarriers. Controlled CHX release was achieved by mHAP and HAP nanocarriers for 120 days. The addition of 5% nanocarrier increased the surface roughness but did not negatively affect the DC and the surface hardness of the resin composites.
MICROSCOPY RESEARCH AND TECHNIQUE
(2023)
Article
Biochemistry & Molecular Biology
Cevahir Altinkaynak, Merve Turk, Nazlican Yangin, Nalan Ozdemir
Summary: In this study, myoglobin-zinc assisted hybrid nanoflowers (MbNFs@Zn) were fabricated and characterized for their morphology and catalytic performance. The optimum morphology was obtained at pH 6 and 0.1 mg mL(-1), with a size of 5-6 μm and an encapsulation yield of 95%. MbNFs@Zn showed high peroxidase mimic activity at pH 4 and exhibited efficient decolorization of azo dyes, making it a potential material for industrial applications.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Biotechnology & Applied Microbiology
Cevahir Altinkaynak, Ebru Haciosmanoglu, Murat Ekremoglu, Mayram Hacioglu, Nalan Ozdemir
Summary: This study synthesized Aloe vera-incorporated hybrid nanoflowers (AV-Nfs) using different concentrations of Aloe vera extract. The most uniform morphologies were obtained at a concentration of 2 mL. The AV-Nfs were well characterized and showed high peroxidase-mimicking activity, antioxidant activity, and enhanced wound healing and antimicrobial properties.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
M. Sakir, N. Torun, N. Kayaci, I. Torun, M. Kalay, M. S. Onses
Summary: This manuscript presents a method for the fabrication of silver nanoflowers with high surface-enhanced Raman scattering (SERS) activity and unique morphology. The nanoflowers are formed through seed-mediated growth of silver nanostructures over gold nanoparticles on hemispherical polymer features. The silver nanoflowers exhibit high SERS activity, allowing for detection of rhodamine 6G at a concentration of 100 pM. This fabrication method has great potential for anti-counterfeiting applications.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Nanoscience & Nanotechnology
Abidin Esidir, Nilgun Kayaci, N. Burak Kiremitler, Mustafa Kalay, Furkan Sahin, Gulay Sezer, Murat Kaya, M. Serdar Onses
Summary: Counterfeit products in the pharmaceutical and food industries pose increasing threats to health. A study has developed security labels using food-grade materials, such as corn starch, to prevent counterfeiting. These labels, composed of fluorescent microparticles, offer a low-cost and sustainable solution in the fight against counterfeiting, with promising performance in terms of uniqueness and randomness.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Abidin Esidir, Nilgun Kayaci, N. Burak Kiremitler, Mustafa Kalay, Furkan Sahin, Gulay Sezer, Murat Kaya, M. Serdar Onses
Summary: Counterfeit products in the pharmaceutical and food industries are a growing threat to health. This study presents the development of security labels using food-grade materials, specifically food-grade corn starch and a food colorant. The labels are created through spin-coating and transfer onto an edible gelatin film, with randomly positioned particles used to construct a physically unclonable function (PUF)-based security label. The performance of the PUFs demonstrates their potential in preventing counterfeiting, and their biocompatibility is confirmed through cell assays.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Serkan Dayan, Namik Ozdemir, Digdem Erdener, Osman Dayan, Bekir cetinkaya
Summary: A new cationic ruthenium(II) complex (2) was synthesized and fully characterized. The immobilized Ru(II)-RGO-TiO2@FTO electrode showed moderately good sensitivity for glucose sensing. Modifications of the electrode can be made to improve the performance of future biosensor devices.
NEW JOURNAL OF CHEMISTRY
(2023)